Found 321 hits with Last Name = 'zhang' and Initial = 'xq' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Probable maltase-glucoamylase 2
(Homo sapiens) | BDBM50457916
(CHEBI:67537 | Terphenyllin)Show SMILES COc1cc(c(OC)c(O)c1-c1ccc(O)cc1)-c1ccc(O)cc1 Show InChI InChI=1S/C20H18O5/c1-24-17-11-16(12-3-7-14(21)8-4-12)20(25-2)19(23)18(17)13-5-9-15(22)10-6-13/h3-11,21-23H,1-2H3 | UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description
Non-competitive inhibition of human alpha-glucosidase expressed in Saccharomyces cerevisiae using p-nitrophenyl-alpha-D-glucopyranoside as substrate ... |
Eur J Med Chem 146: 232-244 (2018)
Article DOI: 10.1016/j.ejmech.2018.01.057
BindingDB Entry DOI: 10.7270/Q29P3494 |
More data for this
Ligand-Target Pair | |
Probable maltase-glucoamylase 2
(Homo sapiens) | BDBM50457899
(CHEMBL4210494)Show SMILES COc1cc(-c2ccc(O)cc2)c(OC)c(OCCC(C)C)c1-c1ccc(O)cc1 Show InChI InChI=1S/C25H28O5/c1-16(2)13-14-30-25-23(18-7-11-20(27)12-8-18)22(28-3)15-21(24(25)29-4)17-5-9-19(26)10-6-17/h5-12,15-16,26-27H,13-14H2,1-4H3 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description
Non-competitive inhibition of human alpha-glucosidase expressed in Saccharomyces cerevisiae using p-nitrophenyl-alpha-D-glucopyranoside as substrate ... |
Eur J Med Chem 146: 232-244 (2018)
Article DOI: 10.1016/j.ejmech.2018.01.057
BindingDB Entry DOI: 10.7270/Q29P3494 |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50129952
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of PARP-1 (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human)) | BDBM27566
(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-2 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431782
(CHEMBL2347039)Show SMILES CC#CCn1c(nc2ccn(Cc3nc(C)c4ccccc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H27N7O/c1-3-4-13-32-24(33)23-21(29-25(32)31-12-7-8-18(26)15-31)11-14-30(23)16-22-27-17(2)19-9-5-6-10-20(19)28-22/h5-6,9-11,14,18H,7-8,12-13,15-16,26H2,1-2H3/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431785
(CHEMBL2347036)Show SMILES CC#CCn1c(nc2ccn(Cc3ccc4ccc(F)cc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H25FN6O/c1-2-3-12-32-24(33)23-21(29-25(32)31-11-4-5-19(27)15-31)10-13-30(23)16-20-9-7-17-6-8-18(26)14-22(17)28-20/h6-10,13-14,19H,4-5,11-12,15-16,27H2,1H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27566
(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431784
(CHEMBL2347037)Show SMILES CC#CCn1c(nc2ccn(Cc3cnc4ccccc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H25N7O/c1-2-3-12-31-23(32)22-21(28-24(31)30-11-6-7-17(25)15-30)10-13-29(22)16-18-14-26-19-8-4-5-9-20(19)27-18/h4-5,8-10,13-14,17H,6-7,11-12,15-16,25H2,1H3/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431791
(CHEMBL2346926)Show SMILES CC#CCn1c(nc2ccn(Cc3ccc4ccccc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H26N6O/c1-2-3-14-31-24(32)23-22(28-25(31)30-13-6-8-19(26)16-30)12-15-29(23)17-20-11-10-18-7-4-5-9-21(18)27-20/h4-5,7,9-12,15,19H,6,8,13-14,16-17,26H2,1H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50226527
(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)Show InChI InChI=1S/C10H15N3/c1-8(12)13-7-10-4-2-3-9(5-10)6-11/h2-5H,6-7,11H2,1H3,(H2,12,13) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human iNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hr |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00578
BindingDB Entry DOI: 10.7270/Q2H9993V |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431786
(CHEMBL2347035)Show SMILES CC#CCn1c(nc2ccn(Cc3ccc4ccc(Cl)cc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H25ClN6O/c1-2-3-12-32-24(33)23-21(29-25(32)31-11-4-5-19(27)15-31)10-13-30(23)16-20-9-7-17-6-8-18(26)14-22(17)28-20/h6-10,13-14,19H,4-5,11-12,15-16,27H2,1H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579039
(CHEMBL4853039)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3ccco3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431788
(CHEMBL2346929)Show SMILES CC#CCn1c(nc2ccn(Cc3ccc4cc(F)ccc4n3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H25FN6O/c1-2-3-12-32-24(33)23-22(29-25(32)31-11-4-5-19(27)15-31)10-13-30(23)16-20-8-6-17-14-18(26)7-9-21(17)28-20/h6-10,13-14,19H,4-5,11-12,15-16,27H2,1H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579053
(CHEMBL4868405)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4cccs4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431783
(CHEMBL2347038)Show SMILES CC#CCn1c(nc2ccn(Cc3nc4ccccc4nc3C)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H27N7O/c1-3-4-13-32-24(33)23-21(29-25(32)31-12-7-8-18(26)15-31)11-14-30(23)16-22-17(2)27-19-9-5-6-10-20(19)28-22/h5-6,9-11,14,18H,7-8,12-13,15-16,26H2,1-2H3/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579038
(CHEMBL4847227)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3cccs3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579054
(CHEMBL4876922)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccco4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579055
(CHEMBL4856808)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccncc4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579037
(CHEMBL4849380)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3ccccn3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579049
(CHEMBL4862002)Show SMILES COc1ccc(CN2CCN(Cc3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)CC2)c(OC)c1OC | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579035
(CHEMBL4848834)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3cccnc3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579048
(CHEMBL4863696)Show SMILES COc1cc(CN2CCN(Cc3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)CC2)cc(OC)c1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579036
(CHEMBL4867555)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3ccncc3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431793
(CHEMBL2346924)Show SMILES CC#CCn1c(nc2ccn(Cc3nc4ccccc4[nH]3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C23H25N7O/c1-2-3-12-30-22(31)21-19(27-23(30)29-11-6-7-16(24)14-29)10-13-28(21)15-20-25-17-8-4-5-9-18(17)26-20/h4-5,8-10,13,16H,6-7,11-12,14-15,24H2,1H3,(H,25,26)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579050
(CHEMBL4876971)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccc(cc4)C(F)(F)F)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50563975
(CHEMBL4799284) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of PARP-1 (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579065
(CHEMBL4873634)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)c3cncnc3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579045
(CHEMBL4876352)Show SMILES Cc1ccc(CN2CCN(Cc3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)CC2)cc1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579046
(CHEMBL4854276)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccc(Cl)cc4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579041
(CHEMBL4853266)Show SMILES Cc1cc(C)cc(COC(=O)N2CCN(Cc3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)CC2)c1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579047
(CHEMBL4865730)Show SMILES COc1ccc(CN2CCN(Cc3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)CC2)cc1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579051
(CHEMBL4875196)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccc(F)cc4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579058
(CHEMBL4855360)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)c3ccccc3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579059
(CHEMBL4848408)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)c3ccccc3O)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579026
(CHEMBL4868456)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)C3CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579029
(CHEMBL4870649)Show SMILES CC(C)C(=O)N1CCN(Cc2c(O)cc(O)c3c2oc(cc3=O)-c2ccc(O)cc2)CC1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579060
(CHEMBL4862834)Show SMILES Oc1ccc(cc1)N1CCN(Cc2c(O)cc(O)c3c2oc(cc3=O)-c2ccc(O)cc2)CC1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579052
(CHEMBL4874308)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC4CCCO4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579033
(CHEMBL4847485)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)c3cccc(c3)C(F)(F)F)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579030
(CHEMBL4863798)Show SMILES CC(=O)N1CCN(Cc2c(O)cc(O)c3c2oc(cc3=O)-c2ccc(O)cc2)CC1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579032
(CHEMBL4854910)Show SMILES COc1ccc(cc1)C(=O)N1CCN(Cc2c(O)cc(O)c3c2oc(cc3=O)-c2ccc(O)cc2)CC1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50381853
(CHEMBL2023067)Show SMILES N[C@@H]1CCCN(C1)c1nc2c(Br)c[nH]c2c(=O)n1Cc1ccccc1C#N |r| Show InChI InChI=1S/C19H19BrN6O/c20-15-9-23-17-16(15)24-19(25-7-3-6-14(22)11-25)26(18(17)27)10-13-5-2-1-4-12(13)8-21/h1-2,4-5,9,14,23H,3,6-7,10-11,22H2/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431795
(CHEMBL2346922)Show SMILES CC#CCn1c(nc2ccn(Cc3ncccn3)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C20H23N7O/c1-2-3-11-27-19(28)18-16(24-20(27)26-10-4-6-15(21)13-26)7-12-25(18)14-17-22-8-5-9-23-17/h5,7-9,12,15H,4,6,10-11,13-14,21H2,1H3/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431794
(CHEMBL2346923)Show SMILES CC#CCn1c(nc2ccn(Cc3c[nH]c4ccccc34)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H26N6O/c1-2-3-12-30-23(31)22-21(27-24(30)29-11-6-7-18(25)16-29)10-13-28(22)15-17-14-26-20-9-5-4-8-19(17)20/h4-5,8-10,13-14,18,26H,6-7,11-12,15-16,25H2,1H3/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579057
(CHEMBL4861133)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4ccoc4)CC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579040
(CHEMBL4850517)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)OCc3ccccc3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579028
(CHEMBL4866335)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)C3CCCCC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27496
((4Z)-4-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,2,...)Show InChI InChI=1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of PARP-1 (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50579027
(CHEMBL4869388)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(CC3)C(=O)C3CCC3)c2o1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human full-length PARP-1 using biotinylated substrate |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00735
BindingDB Entry DOI: 10.7270/Q2BC43DN |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50431792
(CHEMBL2346925)Show SMILES CC#CCn1c(nc2ccn(Cc3ccnc4ccccc34)c2c1=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H26N6O/c1-2-3-14-31-24(32)23-22(28-25(31)30-13-6-7-19(26)17-30)11-15-29(23)16-18-10-12-27-21-9-5-4-8-20(18)21/h4-5,8-12,15,19H,6-7,13-14,16-17,26H2,1H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins |
Bioorg Med Chem 21: 1749-55 (2013)
Article DOI: 10.1016/j.bmc.2013.01.062
BindingDB Entry DOI: 10.7270/Q2R78GMR |
More data for this
Ligand-Target Pair | |
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