Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aryl hydrocarbon receptor (Rattus norvegicus) | BDBM50240990 (2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosol | J Med Chem 51: 5135-9 (2008) Article DOI: 10.1021/jm800418z BindingDB Entry DOI: 10.7270/Q23X86F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383051 (CHEMBL2031302) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383049 (CHEMBL2031300) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383047 (CHEMBL2031298) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383052 (CHEMBL2031303) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383046 (CHEMBL2031297) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383054 (CHEMBL2031305) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383053 (CHEMBL2031304) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383048 (CHEMBL2031299) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383056 (CHEMBL2031307) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383055 (CHEMBL2031306) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.46 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383043 (CHEMBL2031309) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.02 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383057 (CHEMBL2031308) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383044 (CHEMBL2031311 | US10774068, Example 96 | US1142756...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383050 (CHEMBL2031301) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383045 (CHEMBL2031312) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aryl hydrocarbon receptor (Rattus norvegicus) | BDBM50240990 (2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosol | J Med Chem 51: 5135-9 (2008) Article DOI: 10.1021/jm800418z BindingDB Entry DOI: 10.7270/Q23X86F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383059 (CHEMBL2031313) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383058 (CHEMBL2031310) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50383044 (CHEMBL2031311 | US10774068, Example 96 | US1142756...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of ErbB2 by time-resolved fluorometry | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50383045 (CHEMBL2031312) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of ErbB2 by time-resolved fluorometry | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair |