Compile Data Set for Download or QSAR

Found 157 hits with Last Name = 'barnaby' and Initial = 'o'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50240277 (CHEMBL4061793) Show SMILES Fc1cc(NCC23CCCN2CCC3)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C17H20ClFN4O2S2/c18-12-9-15(27(24,25)22-16-20-5-8-26-16)13(19)10-14(12)21-11-17-3-1-6-23(17)7-2-4-17/h5,8-10,21H,1-4,6-7,11H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Mus musculus)	BDBM50261077 (CHEMBL4072883) Show SMILES Fc1cc(NC[C@H]2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-6-14(25(21,22)20-15-18-3-5-24-15)12(17)7-13(11)19-8-10-2-1-4-23-9-10/h3,5-7,10,19H,1-2,4,8-9H2,(H,18,20)/t10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of Nav1.7 in adult mouse DRG neurons assessed as inhibition of fast-inactivating TTX-sensitive sodium currents				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261096 (CHEMBL4075332 | US10836758, Example 73) Show SMILES Fc1cc(NCCC2CCS(=O)(=O)CC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O4S3/c17-12-9-15(28(24,25)21-16-20-5-6-26-16)13(18)10-14(12)19-4-1-11-2-7-27(22,23)8-3-11/h5-6,9-11,19H,1-4,7-8H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261088 (CHEMBL4094490 | US10836758, Example 72) Show SMILES Fc1cc(NCCC2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-8-15(26(22,23)21-16-20-5-7-25-16)13(18)9-14(12)19-4-3-11-2-1-6-24-10-11/h5,7-9,11,19H,1-4,6,10H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261090 (CHEMBL4102624) Show SMILES Fc1cc(NCC2CCCC(=O)C2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H17ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-4-5-25-16)13(18)8-14(12)20-9-10-2-1-3-11(22)6-10/h4-5,7-8,10,20H,1-3,6,9H2,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Mus musculus)	BDBM50261077 (CHEMBL4072883) Show SMILES Fc1cc(NC[C@H]2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-6-14(25(21,22)20-15-18-3-5-24-15)12(17)7-13(11)19-8-10-2-1-4-23-9-10/h3,5-7,10,19H,1-2,4,8-9H2,(H,18,20)/t10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav1.7 inactivated state form expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophys...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261075 (CHEMBL4087220 | US10836758, Example 7) Show SMILES Fc1cc(NCC2COCCO2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O4S2/c15-10-5-13(25(20,21)19-14-17-1-4-24-14)11(16)6-12(10)18-7-9-8-22-2-3-23-9/h1,4-6,9,18H,2-3,7-8H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261077 (CHEMBL4072883) Show SMILES Fc1cc(NC[C@H]2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-6-14(25(21,22)20-15-18-3-5-24-15)12(17)7-13(11)19-8-10-2-1-4-23-9-10/h3,5-7,10,19H,1-2,4,8-9H2,(H,18,20)/t10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261140 (CHEMBL4102233) Show SMILES Fc1cc(NC[C@H]2CCCO[C@@H]2c2ccccc2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C21H21ClFN3O3S2/c22-16-11-19(31(27,28)26-21-24-8-10-30-21)17(23)12-18(16)25-13-15-7-4-9-29-20(15)14-5-2-1-3-6-14/h1-3,5-6,8,10-12,15,20,25H,4,7,9,13H2,(H,24,26)/t15-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50261077 (CHEMBL4072883) Show SMILES Fc1cc(NC[C@H]2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-6-14(25(21,22)20-15-18-3-5-24-15)12(17)7-13(11)19-8-10-2-1-4-23-9-10/h3,5-7,10,19H,1-2,4,8-9H2,(H,18,20)/t10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human recombinant Nav1.7 inactivated state form expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophys...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261141 (CHEMBL4100176) Show SMILES [#6]-[#8]\[#7]=[#6]-1/[#6]-[#6]-[#6](-[#6]-[#7]-c2cc(F)c(cc2Cl)S(=O)(=O)[#7]-c2nccs2)-[#6]-[#6]-1 Show InChI InChI=1S/C17H20ClFN4O3S2/c1-26-22-12-4-2-11(3-5-12)10-21-15-9-14(19)16(8-13(15)18)28(24,25)23-17-20-6-7-27-17/h6-9,11,21H,2-5,10H2,1H3,(H,20,23)/b22-12-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261097 (CHEMBL4104727) Show SMILES [H][C@@]12OCC[C@]1(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)CCO2 |r,wU:5.6,1.0,(5.91,-10.76,;5.92,-12.31,;7.27,-11.85,;8.24,-13.05,;7.4,-14.34,;5.92,-13.94,;5.91,-15.48,;7.25,-16.25,;8.58,-15.48,;8.58,-13.94,;9.91,-13.17,;9.91,-11.63,;11.25,-13.93,;11.25,-15.48,;9.92,-16.25,;9.92,-17.79,;12.58,-13.15,;11.8,-11.81,;13.35,-11.81,;13.91,-13.92,;15.25,-13.15,;16.65,-13.77,;17.68,-12.62,;16.9,-11.29,;15.4,-11.62,;4.48,-14.49,;3.51,-13.29,;4.35,-12,)| Show InChI InChI=1S/C16H17ClFN3O4S2/c17-10-7-13(27(22,23)21-15-19-3-6-26-15)11(18)8-12(10)20-9-16-1-4-24-14(16)25-5-2-16/h3,6-8,14,20H,1-2,4-5,9H2,(H,19,21)/t14-,16+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261129 (CHEMBL4064762 | US10836758, Example 71) Show SMILES Fc1cc(NCCC2CCOCC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-9-15(26(22,23)21-16-20-5-8-25-16)13(18)10-14(12)19-4-1-11-2-6-24-7-3-11/h5,8-11,19H,1-4,6-7H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261137 (CHEMBL4102647 | US10836758, Example 11) Show SMILES Fc1cc(NCC2CCOCC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-7-14(25(21,22)20-15-18-3-6-24-15)12(17)8-13(11)19-9-10-1-4-23-5-2-10/h3,6-8,10,19H,1-2,4-5,9H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261122 (CHEMBL4073353 | US10836758, Example 37) Show SMILES Fc1cc(NCCCC2CCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-8-15(26(22,23)21-16-20-5-7-25-16)13(18)9-14(12)19-4-1-2-11-3-6-24-10-11/h5,7-9,11,19H,1-4,6,10H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261092 (CHEMBL4073324) Show SMILES Fc1cc(NCC2CCC(=O)CC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H17ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-5-6-25-16)13(18)8-14(12)20-9-10-1-3-11(22)4-2-10/h5-8,10,20H,1-4,9H2,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261147 (CHEMBL4094879) Show SMILES O[C@@H]1CCC[C@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)C1 |r| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-4-5-25-16)13(18)8-14(12)20-9-10-2-1-3-11(22)6-10/h4-5,7-8,10-11,20,22H,1-3,6,9H2,(H,19,21)/t10-,11+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261139 (CHEMBL4064295) Show SMILES CC(C)(C)[C@H]1OCCC[C@@H]1CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C19H25ClFN3O3S2/c1-19(2,3)17-12(5-4-7-27-17)11-23-15-10-14(21)16(9-13(15)20)29(25,26)24-18-22-6-8-28-18/h6,8-10,12,17,23H,4-5,7,11H2,1-3H3,(H,22,24)/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261094 (CHEMBL4092435) Show SMILES O[C@H]1CC[C@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)CC1 |r,wU:4.4,wD:1.0,(42.45,-33.72,;43.79,-32.96,;45.12,-33.73,;46.46,-32.97,;46.45,-31.43,;47.79,-30.66,;47.79,-29.12,;49.12,-28.35,;49.13,-26.81,;50.46,-26.04,;50.45,-24.5,;51.79,-26.8,;51.8,-28.35,;50.46,-29.12,;50.46,-30.66,;53.12,-26.02,;52.34,-24.69,;53.89,-24.68,;54.46,-26.79,;55.79,-26.02,;57.19,-26.64,;58.22,-25.49,;57.44,-24.16,;55.94,-24.49,;45.12,-30.66,;43.79,-31.42,)| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-5-6-25-16)13(18)8-14(12)20-9-10-1-3-11(22)4-2-10/h5-8,10-11,20,22H,1-4,9H2,(H,19,21)/t10-,11-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261073 (CHEMBL4074392) Show SMILES Fc1cc(NCC2CCCC3(C2)OCCO3)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C18H21ClFN3O4S2/c19-13-8-16(29(24,25)23-17-21-4-7-28-17)14(20)9-15(13)22-11-12-2-1-3-18(10-12)26-5-6-27-18/h4,7-9,12,22H,1-3,5-6,10-11H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261118 (CHEMBL4071736) Show SMILES O[C@]12CCC[C@@]1(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)CCC2 |r,wU:5.6,1.0,(24.36,-1.35,;24.38,-2.89,;22.8,-2.58,;21.96,-3.88,;22.93,-5.07,;24.37,-4.52,;24.37,-6.06,;25.7,-6.83,;27.03,-6.06,;27.04,-4.52,;28.36,-3.75,;28.36,-2.21,;29.7,-4.51,;29.71,-6.06,;28.37,-6.83,;28.37,-8.37,;31.03,-3.73,;30.25,-2.4,;31.8,-2.39,;32.37,-4.5,;33.7,-3.73,;35.1,-4.35,;36.13,-3.2,;35.35,-1.87,;33.85,-2.2,;25.86,-4.92,;26.69,-3.63,;25.72,-2.43,)| Show InChI InChI=1S/C18H21ClFN3O3S2/c19-12-9-15(28(25,26)23-16-21-7-8-27-16)13(20)10-14(12)22-11-17-3-1-5-18(17,24)6-2-4-17/h7-10,22,24H,1-6,11H2,(H,21,23)/t17-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261121 (CHEMBL4101414 | US10836758, Example 38) Show SMILES Fc1cc(NCC2CCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O3S2/c15-10-5-13(24(20,21)19-14-17-2-4-23-14)11(16)6-12(10)18-7-9-1-3-22-8-9/h2,4-6,9,18H,1,3,7-8H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261071 (CHEMBL4100208 | US10836758, Example 40) Show SMILES Fc1cc(NCC2CCCO2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O3S2/c15-10-6-13(24(20,21)19-14-17-3-5-23-14)11(16)7-12(10)18-8-9-2-1-4-22-9/h3,5-7,9,18H,1-2,4,8H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261161 (CHEMBL4076229) Show SMILES Fc1cc(NCCC2CCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-7-14(25(21,22)20-15-19-4-6-24-15)12(17)8-13(11)18-3-1-10-2-5-23-9-10/h4,6-8,10,18H,1-3,5,9H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261074 (CHEMBL4092463 | US10836758, Example 10) Show SMILES Fc1cc(NCC2CCCCO2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-7-14(25(21,22)20-15-18-4-6-24-15)12(17)8-13(11)19-9-10-3-1-2-5-23-10/h4,6-8,10,19H,1-3,5,9H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261136 (CHEMBL4083744) Show SMILES Fc1cc(NCC2OCCO2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C13H13ClFN3O4S2/c14-8-5-11(24(19,20)18-13-16-1-4-23-13)9(15)6-10(8)17-7-12-21-2-3-22-12/h1,4-6,12,17H,2-3,7H2,(H,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261143 (CHEMBL4061129) Show SMILES OC12CC3CC(C1)CC(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)(C3)C2 |TLB:28:8:2.3.4:6,THB:28:3:6:29.8.7,7:8:2:4.5.6,7:5:2:29.28.8,9:8:2.3.4:6| Show InChI InChI=1S/C20H23ClFN3O3S2/c21-14-4-17(30(27,28)25-18-23-1-2-29-18)15(22)5-16(14)24-11-19-6-12-3-13(7-19)9-20(26,8-12)10-19/h1-2,4-5,12-13,24,26H,3,6-11H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261142 (CHEMBL4082252) Show SMILES Fc1cc(NCC2CCS(=O)(=O)C2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O4S3/c15-10-5-13(26(22,23)19-14-17-2-3-24-14)11(16)6-12(10)18-7-9-1-4-25(20,21)8-9/h2-3,5-6,9,18H,1,4,7-8H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261091 (CHEMBL4084685) Show SMILES O[C@H]1CCC[C@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)C1 |r| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-4-5-25-16)13(18)8-14(12)20-9-10-2-1-3-11(22)6-10/h4-5,7-8,10-11,20,22H,1-3,6,9H2,(H,19,21)/t10-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	281	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261072 (CHEMBL4092025) Show SMILES Fc1cc(NC[C@@H]2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C15H17ClFN3O3S2/c16-11-6-14(25(21,22)20-15-18-3-5-24-15)12(17)7-13(11)19-8-10-2-1-4-23-9-10/h3,5-7,10,19H,1-2,4,8-9H2,(H,18,20)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261127 (CHEMBL4062009) Show SMILES Fc1cc(NC2CCOCC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O3S2/c15-10-7-13(24(20,21)19-14-17-3-6-23-14)11(16)8-12(10)18-9-1-4-22-5-2-9/h3,6-9,18H,1-2,4-5H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261159 (CHEMBL4098747) Show SMILES Fc1cc(NCCC2CCC3(CC2)OCCO3)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H23ClFN3O4S2/c20-14-11-17(30(25,26)24-18-23-7-10-29-18)15(21)12-16(14)22-6-3-13-1-4-19(5-2-13)27-8-9-28-19/h7,10-13,22H,1-6,8-9H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261095 (CHEMBL4068484) Show SMILES O[C@H]1CC[C@@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)CC1 |r,wU:4.4,1.0,(4.65,-11.88,;5.99,-11.12,;6,-9.58,;7.33,-8.82,;8.66,-9.59,;9.99,-8.82,;9.99,-7.28,;11.33,-6.51,;11.33,-4.97,;12.66,-4.2,;12.65,-2.66,;13.99,-4.96,;14,-6.51,;12.66,-7.28,;12.66,-8.82,;15.32,-4.18,;14.54,-2.85,;16.09,-2.84,;16.66,-4.95,;17.99,-4.18,;19.4,-4.8,;20.42,-3.66,;19.65,-2.33,;18.14,-2.65,;8.66,-11.13,;7.32,-11.89,)| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-5-6-25-16)13(18)8-14(12)20-9-10-1-3-11(22)4-2-10/h5-8,10-11,20,22H,1-4,9H2,(H,19,21)/t10-,11+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261148 (CHEMBL4095822) Show SMILES Fc1cc(NCC2CCC3(CC2)OCCO3)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C18H21ClFN3O4S2/c19-13-9-16(29(24,25)23-17-21-5-8-28-17)14(20)10-15(13)22-11-12-1-3-18(4-2-12)26-6-7-27-18/h5,8-10,12,22H,1-4,6-7,11H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261078 (CHEMBL4084268) Show SMILES CC(C)(C)[C@@H]1OCCC[C@@H]1CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C19H25ClFN3O3S2/c1-19(2,3)17-12(5-4-7-27-17)11-23-15-10-14(21)16(9-13(15)20)29(25,26)24-18-22-6-8-28-18/h6,8-10,12,17,23H,4-5,7,11H2,1-3H3,(H,22,24)/t12-,17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	415	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261093 (CHEMBL4064737) Show SMILES Fc1cc(-[#7]-[#6]-[#6]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#7]/[#8]-[#6]-c2ccccc2)c(Cl)cc1S(=O)(=O)[#7]-c1nccs1 Show InChI InChI=1S/C23H24ClFN4O3S2/c24-19-12-22(34(30,31)29-23-26-10-11-33-23)20(25)13-21(19)27-14-16-6-8-18(9-7-16)28-32-15-17-4-2-1-3-5-17/h1-5,10-13,16,27H,6-9,14-15H2,(H,26,29)/b28-18-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	444	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261098 (CHEMBL4071860) Show SMILES [H][C@@]12OCC[C@]1(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)CCCO2 |r| Show InChI InChI=1S/C17H19ClFN3O4S2/c18-11-8-14(28(23,24)22-16-20-4-7-27-16)12(19)9-13(11)21-10-17-2-1-5-25-15(17)26-6-3-17/h4,7-9,15,21H,1-3,5-6,10H2,(H,20,22)/t15-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	614	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261128 (CHEMBL4084713) Show SMILES CC1CC(CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)CC(C)O1 Show InChI InChI=1S/C17H21ClFN3O3S2/c1-10-5-12(6-11(2)25-10)9-21-15-8-14(19)16(7-13(15)18)27(23,24)22-17-20-3-4-26-17/h3-4,7-8,10-12,21H,5-6,9H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	706	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261095 (CHEMBL4068484) Show SMILES O[C@H]1CC[C@@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)CC1 |r,wU:4.4,1.0,(4.65,-11.88,;5.99,-11.12,;6,-9.58,;7.33,-8.82,;8.66,-9.59,;9.99,-8.82,;9.99,-7.28,;11.33,-6.51,;11.33,-4.97,;12.66,-4.2,;12.65,-2.66,;13.99,-4.96,;14,-6.51,;12.66,-7.28,;12.66,-8.82,;15.32,-4.18,;14.54,-2.85,;16.09,-2.84,;16.66,-4.95,;17.99,-4.18,;19.4,-4.8,;20.42,-3.66,;19.65,-2.33,;18.14,-2.65,;8.66,-11.13,;7.32,-11.89,)| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-5-6-25-16)13(18)8-14(12)20-9-10-1-3-11(22)4-2-10/h5-8,10-11,20,22H,1-4,9H2,(H,19,21)/t10-,11+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -50 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261118 (CHEMBL4071736) Show SMILES O[C@]12CCC[C@@]1(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)CCC2 |r,wU:5.6,1.0,(24.36,-1.35,;24.38,-2.89,;22.8,-2.58,;21.96,-3.88,;22.93,-5.07,;24.37,-4.52,;24.37,-6.06,;25.7,-6.83,;27.03,-6.06,;27.04,-4.52,;28.36,-3.75,;28.36,-2.21,;29.7,-4.51,;29.71,-6.06,;28.37,-6.83,;28.37,-8.37,;31.03,-3.73,;30.25,-2.4,;31.8,-2.39,;32.37,-4.5,;33.7,-3.73,;35.1,-4.35,;36.13,-3.2,;35.35,-1.87,;33.85,-2.2,;25.86,-4.92,;26.69,-3.63,;25.72,-2.43,)| Show InChI InChI=1S/C18H21ClFN3O3S2/c19-12-9-15(28(25,26)23-16-21-7-8-27-16)13(20)10-14(12)22-11-17-3-1-5-18(17,24)6-2-4-17/h7-10,22,24H,1-6,11H2,(H,21,23)/t17-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -50 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261076 (CHEMBL4099769) Show SMILES Fc1cc(NC2CCCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C14H15ClFN3O3S2/c15-10-6-13(24(20,21)19-14-17-3-5-23-14)11(16)7-12(10)18-9-2-1-4-22-8-9/h3,5-7,9,18H,1-2,4,8H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	796	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261122 (CHEMBL4073353 | US10836758, Example 37) Show SMILES Fc1cc(NCCCC2CCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-8-15(26(22,23)21-16-20-5-7-25-16)13(18)9-14(12)19-4-1-2-11-3-6-24-10-11/h5,7-9,11,19H,1-4,6,10H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -50 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261138 (CHEMBL4065798) Show SMILES Fc1cc(NCCC2CCCCO2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-9-15(26(22,23)21-16-20-6-8-25-16)13(18)10-14(12)19-5-4-11-3-1-2-7-24-11/h6,8-11,19H,1-5,7H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	874	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261119 (CHEMBL4089301) Show SMILES OC1C2CC3CC1CC(CNc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)(C3)C2 |TLB:29:8:1.2.3:5,0:1:7.29.8:3.4.5,0:1:5:7.8.28,THB:29:2:5:7.8.28,28:8:1:3.4.5,28:4:1:7.29.8,9:8:1.2.3:5,(19.79,-20.93,;21.33,-20.94,;22.18,-19.63,;21.12,-18.45,;21.09,-16.84,;20.39,-18.08,;21.39,-19.19,;22.7,-18.68,;23.51,-17.49,;24.85,-16.73,;24.85,-15.19,;26.18,-14.42,;26.19,-12.87,;27.51,-12.1,;27.51,-10.56,;28.85,-12.87,;28.85,-14.42,;27.52,-15.19,;27.52,-16.73,;30.18,-12.09,;29.4,-10.75,;30.95,-10.74,;31.52,-12.86,;32.85,-12.08,;34.25,-12.71,;35.28,-11.56,;34.5,-10.23,;33,-10.55,;22.51,-16.35,;23.6,-19.12,)| Show InChI InChI=1S/C20H23ClFN3O3S2/c21-14-5-17(30(27,28)25-19-23-1-2-29-19)15(22)6-16(14)24-10-20-7-11-3-12(8-20)18(26)13(4-11)9-20/h1-2,5-6,11-13,18,24,26H,3-4,7-10H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	916	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261120 (CHEMBL4069801) Show SMILES Fc1cc(NC2CC3CCC2O3)c(Cl)cc1S(=O)(=O)Nc1nccs1 |TLB:4:5:9.8:11| Show InChI InChI=1S/C15H15ClFN3O3S2/c16-9-6-14(25(21,22)20-15-18-3-4-24-15)10(17)7-11(9)19-12-5-8-1-2-13(12)23-8/h3-4,6-8,12-13,19H,1-2,5H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	931	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261094 (CHEMBL4092435) Show SMILES O[C@H]1CC[C@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)CC1 |r,wU:4.4,wD:1.0,(42.45,-33.72,;43.79,-32.96,;45.12,-33.73,;46.46,-32.97,;46.45,-31.43,;47.79,-30.66,;47.79,-29.12,;49.12,-28.35,;49.13,-26.81,;50.46,-26.04,;50.45,-24.5,;51.79,-26.8,;51.8,-28.35,;50.46,-29.12,;50.46,-30.66,;53.12,-26.02,;52.34,-24.69,;53.89,-24.68,;54.46,-26.79,;55.79,-26.02,;57.19,-26.64,;58.22,-25.49,;57.44,-24.16,;55.94,-24.49,;45.12,-30.66,;43.79,-31.42,)| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-5-6-25-16)13(18)8-14(12)20-9-10-1-3-11(22)4-2-10/h5-8,10-11,20,22H,1-4,9H2,(H,19,21)/t10-,11-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -50 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261145 (CHEMBL4073933) Show SMILES Fc1cc(NC[C@H]2CCCO[C@H]2c2ccccc2)c(Cl)cc1S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C21H21ClFN3O3S2/c22-16-11-19(31(27,28)26-21-24-8-10-30-21)17(23)12-18(16)25-13-15-7-4-9-29-20(15)14-5-2-1-3-6-14/h1-3,5-6,8,10-12,15,20,25H,4,7,9,13H2,(H,24,26)/t15-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261144 (CHEMBL4097000) Show SMILES Fc1cc(NC2CCOC2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C13H13ClFN3O3S2/c14-9-5-12(23(19,20)18-13-16-2-4-22-13)10(15)6-11(9)17-8-1-3-21-7-8/h2,4-6,8,17H,1,3,7H2,(H,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261089 (CHEMBL4086750) Show SMILES Fc1cc(NC2CC3(COC3)C2)c(Cl)cc1S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C15H15ClFN3O3S2/c16-10-3-13(25(21,22)20-14-18-1-2-24-14)11(17)4-12(10)19-9-5-15(6-9)7-23-8-15/h1-4,9,19H,5-8H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -60 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50261147 (CHEMBL4094879) Show SMILES O[C@@H]1CCC[C@H](CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)C1 |r| Show InChI InChI=1S/C16H19ClFN3O3S2/c17-12-7-15(26(23,24)21-16-19-4-5-25-16)13(18)8-14(12)20-9-10-2-1-3-11(22)6-10/h4-5,7-8,10-11,20,22H,1-3,6,9H2,(H,19,21)/t10-,11+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492-7660, USA. Electronic address: yong-jin.wu@bms.com. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 inactivated state form expressed in HEK293 cells at -50 mV holding potential by by automated patch clamp electrophysiology...				Bioorg Med Chem 25: 5490-5505 (2017) Article DOI: 10.1016/j.bmc.2017.08.012 BindingDB Entry DOI: 10.7270/Q20V8G8N
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 157 total )  |  Next  |  Last  >>

Jump to: