Compile Data Set for Download or QSAR

Found 191 hits with Last Name = 'brewster' and Initial = 'ag'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034767 ((E)-7-(4-{5-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCCCCC[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C39H47NO8/c41-35-17-10-9-16-34(35)39-31(13-4-1-6-18-36(42)43)28-47-38(48-39)20-8-3-11-26-46-32-23-21-29(22-24-32)33(30-14-12-25-40-27-30)15-5-2-7-19-37(44)45/h1,4,9-10,12,14-17,21-25,27,31,38-39,41H,2-3,5-8,11,13,18-20,26,28H2,(H,42,43)(H,44,45)/b4-1-,33-15+/t31-,38+,39+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034762 ((E)-7-(4-{6-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES CC(C)(CCCCCc1ccc(cc1)C(=C/CCCCC(O)=O)\c1cccnc1)[C@H]1OC[C@@H](C\C=C/CCC(O)=O)[C@H](O1)c1ccccc1O Show InChI InChI=1S/C42H53NO7/c1-42(2,41-49-30-34(16-7-3-9-21-38(45)46)40(50-41)36-19-11-12-20-37(36)44)27-13-5-6-15-31-23-25-32(26-24-31)35(33-17-14-28-43-29-33)18-8-4-10-22-39(47)48/h3,7,11-12,14,17-20,23-26,28-29,34,40-41,44H,4-6,8-10,13,15-16,21-22,27,30H2,1-2H3,(H,45,46)(H,47,48)/b7-3-,35-18+/t34-,40+,41+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034758 ((E)-7-(3-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES OC(=O)CCCC\C=C(\c1cccnc1)c1cccc(OCc2ccc(cc2)[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)c1 Show InChI InChI=1S/C41H43NO8/c43-37-17-8-7-16-36(37)40-33(11-3-1-5-18-38(44)45)28-49-41(50-40)30-22-20-29(21-23-30)27-48-34-14-9-12-31(25-34)35(32-13-10-24-42-26-32)15-4-2-6-19-39(46)47/h1,3,7-10,12-17,20-26,33,40-41,43H,2,4-6,11,18-19,27-28H2,(H,44,45)(H,46,47)/b3-1-,35-15+/t33-,40+,41+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036368 ((Z)-6-[2-(1,1-Dimethyl-2-phenyl-ethyl)-4-pyridin-3...) Show SMILES CC(C)(Cc1ccccc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H31NO4/c1-25(2,16-19-10-5-3-6-11-19)24-29-18-21(12-7-4-8-14-22(27)28)23(30-24)20-13-9-15-26-17-20/h3-7,9-11,13,15,17,21,23-24H,8,12,14,16,18H2,1-2H3,(H,27,28)/b7-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036355 ((Z)-6-{2-[1-(2-Cyano-4-fluoro-phenoxy)-1-methyl-et...) Show SMILES CC(C)(Oc1ccc(F)cc1C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H27FN2O5/c1-25(2,33-21-11-10-20(26)13-19(21)14-27)24-31-16-18(7-4-3-5-9-22(29)30)23(32-24)17-8-6-12-28-15-17/h3-4,6,8,10-13,15,18,23-24H,5,7,9,16H2,1-2H3,(H,29,30)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50010960 ((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...) Show SMILES OC(=O)CCCC\C=C(/c1ccccc1)c1cccnc1 Show InChI InChI=1S/C18H19NO2/c20-18(21)12-6-2-5-11-17(15-8-3-1-4-9-15)16-10-7-13-19-14-16/h1,3-4,7-11,13-14H,2,5-6,12H2,(H,20,21)/b17-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034750 ((E)-7-(4-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCc2ccc(cc2)[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C41H43NO8/c43-37-14-8-7-13-36(37)40-33(10-3-1-5-15-38(44)45)28-49-41(50-40)31-19-17-29(18-20-31)27-48-34-23-21-30(22-24-34)35(32-11-9-25-42-26-32)12-4-2-6-16-39(46)47/h1,3,7-9,11-14,17-26,33,40-41,43H,2,4-6,10,15-16,27-28H2,(H,44,45)(H,46,47)/b3-1-,35-12+/t33-,40+,41+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50010960 ((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...) Show SMILES OC(=O)CCCC\C=C(/c1ccccc1)c1cccnc1 Show InChI InChI=1S/C18H19NO2/c20-18(21)12-6-2-5-11-17(15-8-3-1-4-9-15)16-10-7-13-19-14-16/h1,3-4,7-11,13-14H,2,5-6,12H2,(H,20,21)/b17-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036354 ((Z)-6-{2-[1-(4-Fluoro-2-nitro-phenoxy)-1-methyl-et...) Show SMILES CC(C)(Oc1ccc(F)cc1[N+]([O-])=O)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H27FN2O7/c1-24(2,34-20-11-10-18(25)13-19(20)27(30)31)23-32-15-17(7-4-3-5-9-21(28)29)22(33-23)16-8-6-12-26-14-16/h3-4,6,8,10-14,17,22-23H,5,7,9,15H2,1-2H3,(H,28,29)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036362 ((Z)-6-{2-[1-(4-Bromo-phenoxy)-1-methyl-ethyl]-4-py...) Show SMILES CC(C)(Oc1ccc(Br)cc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H28BrNO5/c1-24(2,31-20-12-10-19(25)11-13-20)23-29-16-18(7-4-3-5-9-21(27)28)22(30-23)17-8-6-14-26-15-17/h3-4,6,8,10-15,18,22-23H,5,7,9,16H2,1-2H3,(H,27,28)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036345 ((Z)-6-{2-[1-Methyl-1-(4-methylsulfanyl-2-nitro-phe...) Show SMILES CSc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C25H30N2O7S/c1-25(2,34-21-12-11-19(35-3)14-20(21)27(30)31)24-32-16-18(8-5-4-6-10-22(28)29)23(33-24)17-9-7-13-26-15-17/h4-5,7,9,11-15,18,23-24H,6,8,10,16H2,1-3H3,(H,28,29)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036362 ((Z)-6-{2-[1-(4-Bromo-phenoxy)-1-methyl-ethyl]-4-py...) Show SMILES CC(C)(Oc1ccc(Br)cc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H28BrNO5/c1-24(2,31-20-12-10-19(25)11-13-20)23-29-16-18(7-4-3-5-9-21(27)28)22(30-23)17-8-6-14-26-15-17/h3-4,6,8,10-15,18,22-23H,5,7,9,16H2,1-2H3,(H,27,28)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036364 ((Z)-6-[2-(4-Cyano-phenyl)-4-pyridin-3-yl-[1,3]diox...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H22N2O4/c23-13-16-8-10-17(11-9-16)22-27-15-19(5-2-1-3-7-20(25)26)21(28-22)18-6-4-12-24-14-18/h1-2,4,6,8-12,14,19,21-22H,3,5,7,15H2,(H,25,26)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036361 ((Z)-6-{2-[1-(2-Cyano-4-methyl-phenoxy)-1-methyl-et...) Show SMILES Cc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)C#N Show InChI InChI=1S/C26H30N2O5/c1-18-11-12-22(21(14-18)15-27)33-26(2,3)25-31-17-20(8-5-4-6-10-23(29)30)24(32-25)19-9-7-13-28-16-19/h4-5,7,9,11-14,16,20,24-25H,6,8,10,17H2,1-3H3,(H,29,30)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036361 ((Z)-6-{2-[1-(2-Cyano-4-methyl-phenoxy)-1-methyl-et...) Show SMILES Cc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)C#N Show InChI InChI=1S/C26H30N2O5/c1-18-11-12-22(21(14-18)15-27)33-26(2,3)25-31-17-20(8-5-4-6-10-23(29)30)24(32-25)19-9-7-13-28-16-19/h4-5,7,9,11-14,16,20,24-25H,6,8,10,17H2,1-3H3,(H,29,30)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036349 ((Z)-6-{2-[1-(3-Fluoro-phenoxy)-1-methyl-ethyl]-4-p...) Show SMILES CC(C)(Oc1cccc(F)c1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H28FNO5/c1-24(2,31-20-11-6-10-19(25)14-20)23-29-16-18(8-4-3-5-12-21(27)28)22(30-23)17-9-7-13-26-15-17/h3-4,6-7,9-11,13-15,18,22-23H,5,8,12,16H2,1-2H3,(H,27,28)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036365 ((Z)-6-{2-[1-Methyl-1-(4-methyl-2-nitro-phenoxy)-et...) Show SMILES Cc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C25H30N2O7/c1-17-11-12-21(20(14-17)27(30)31)34-25(2,3)24-32-16-19(8-5-4-6-10-22(28)29)23(33-24)18-9-7-13-26-15-18/h4-5,7,9,11-15,19,23-24H,6,8,10,16H2,1-3H3,(H,28,29)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036372 ((Z)-6-{2-[1-(2-Bromo-phenoxy)-1-methyl-ethyl]-4-py...) Show SMILES CC(C)(Oc1ccccc1Br)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H28BrNO5/c1-24(2,31-20-12-7-6-11-19(20)25)23-29-16-18(9-4-3-5-13-21(27)28)22(30-23)17-10-8-14-26-15-17/h3-4,6-8,10-12,14-15,18,22-23H,5,9,13,16H2,1-2H3,(H,27,28)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034759 (3-(2-{3-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...) Show SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1cccc(OCCOc2cc(ccc2OCCn2ccnc2)C(O)=O)c1 Show InChI InChI=1S/C36H38N2O10/c39-30-11-5-4-10-29(30)34-27(7-2-1-3-12-33(40)41)23-47-36(48-34)26-8-6-9-28(21-26)44-19-20-46-32-22-25(35(42)43)13-14-31(32)45-18-17-38-16-15-37-24-38/h1-2,4-6,8-11,13-16,21-22,24,27,34,36,39H,3,7,12,17-20,23H2,(H,40,41)(H,42,43)/b2-1-/t27-,34+,36+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034745 (3-(2-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...) Show SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccccc1OCCOc1cc(ccc1OCCn1ccnc1)C(O)=O Show InChI InChI=1S/C36H38N2O10/c39-29-11-6-4-9-27(29)34-26(8-2-1-3-13-33(40)41)23-47-36(48-34)28-10-5-7-12-30(28)45-20-21-46-32-22-25(35(42)43)14-15-31(32)44-19-18-38-17-16-37-24-38/h1-2,4-7,9-12,14-17,22,24,26,34,36,39H,3,8,13,18-21,23H2,(H,40,41)(H,42,43)/b2-1-/t26-,34+,36+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034751 ((E)-7-(4-{5-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES CC(C)(CCCCOc1ccc(cc1)C(=C/CCCCC(O)=O)\c1cccnc1)[C@H]1OC[C@@H](C\C=C/CCC(O)=O)[C@H](O1)c1ccccc1O Show InChI InChI=1S/C41H51NO8/c1-41(2,40-49-29-32(14-5-3-7-19-37(44)45)39(50-40)35-17-9-10-18-36(35)43)25-11-12-27-48-33-23-21-30(22-24-33)34(31-15-13-26-42-28-31)16-6-4-8-20-38(46)47/h3,5,9-10,13,15-18,21-24,26,28,32,39-40,43H,4,6-8,11-12,14,19-20,25,27,29H2,1-2H3,(H,44,45)(H,46,47)/b5-3-,34-16+/t32-,39+,40+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034763 ((E)-7-(4-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCC[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C36H41NO8/c38-32-14-8-7-13-31(32)36-28(10-3-1-5-15-33(39)40)25-44-35(45-36)21-23-43-29-19-17-26(18-20-29)30(27-11-9-22-37-24-27)12-4-2-6-16-34(41)42/h1,3,7-9,11-14,17-20,22,24,28,35-36,38H,2,4-6,10,15-16,21,23,25H2,(H,39,40)(H,41,42)/b3-1-,30-12+/t28-,35+,36+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036357 ((Z)-6-{2-[1-Methyl-1-(4-methyl-2-nitro-phenylsulfa...) Show SMILES Cc1ccc(SC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C25H30N2O6S/c1-17-11-12-21(20(14-17)27(30)31)34-25(2,3)24-32-16-19(8-5-4-6-10-22(28)29)23(33-24)18-9-7-13-26-15-18/h4-5,7,9,11-15,19,23-24H,6,8,10,16H2,1-3H3,(H,28,29)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034761 ((E)-7-[4-(2-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCCOc2ccccc2[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C42H45NO9/c44-37-17-9-7-15-35(37)41-32(12-3-1-5-19-39(45)46)29-51-42(52-41)36-16-8-10-18-38(36)50-27-26-49-33-23-21-30(22-24-33)34(31-13-11-25-43-28-31)14-4-2-6-20-40(47)48/h1,3,7-11,13-18,21-25,28,32,41-42,44H,2,4-6,12,19-20,26-27,29H2,(H,45,46)(H,47,48)/b3-1-,34-14+/t32-,41+,42+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034769 ((E)-7-(4-{1-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES CC(C)([C@H]1OC[C@@H](C\C=C/CCC(O)=O)[C@H](O1)c1ccccc1O)c1ccc(cc1)C(=C/CCCCC(O)=O)\c1cccnc1 Show InChI InChI=1S/C37H43NO7/c1-37(2,29-21-19-26(20-22-29)30(27-13-11-23-38-24-27)14-6-4-8-18-34(42)43)36-44-25-28(12-5-3-7-17-33(40)41)35(45-36)31-15-9-10-16-32(31)39/h3,5,9-11,13-16,19-24,28,35-36,39H,4,6-8,12,17-18,25H2,1-2H3,(H,40,41)(H,42,43)/b5-3-,30-14+/t28-,35+,36+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036385 ((Z)-6-{2-[1-(2-Hydroxy-phenoxy)-1-methyl-ethyl]-4-...) Show SMILES CC(C)(Oc1ccccc1O)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H29NO6/c1-24(2,31-20-12-7-6-11-19(20)26)23-29-16-18(9-4-3-5-13-21(27)28)22(30-23)17-10-8-14-25-15-17/h3-4,6-8,10-12,14-15,18,22-23,26H,5,9,13,16H2,1-2H3,(H,27,28)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036386 ((Z)-6-{2-[1-(4-Methanesulfonyl-phenoxy)-1-methyl-e...) Show SMILES CC(C)(Oc1ccc(cc1)S(C)(=O)=O)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H31NO7S/c1-25(2,33-20-11-13-21(14-12-20)34(3,29)30)24-31-17-19(8-5-4-6-10-22(27)28)23(32-24)18-9-7-15-26-16-18/h4-5,7,9,11-16,19,23-24H,6,8,10,17H2,1-3H3,(H,27,28)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036353 ((Z)-6-{2-[1-Methyl-1-(2-methylsulfanyl-phenoxy)-et...) Show SMILES CSc1ccccc1OC(C)(C)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H31NO5S/c1-25(2,31-20-12-7-8-13-21(20)32-3)24-29-17-19(10-5-4-6-14-22(27)28)23(30-24)18-11-9-15-26-16-18/h4-5,7-9,11-13,15-16,19,23-24H,6,10,14,17H2,1-3H3,(H,27,28)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036346 ((Z)-6-{2-[1-(4-Methoxy-2-nitro-phenoxy)-1-methyl-e...) Show SMILES COc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C25H30N2O8/c1-25(2,35-21-12-11-19(32-3)14-20(21)27(30)31)24-33-16-18(8-5-4-6-10-22(28)29)23(34-24)17-9-7-13-26-15-17/h4-5,7,9,11-15,18,23-24H,6,8,10,16H2,1-3H3,(H,28,29)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036380 ((Z)-6-{2-[2-(2-Cyano-phenyl)-1,1-dimethyl-ethyl]-4...) Show SMILES CC(C)(Cc1ccccc1C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C26H30N2O4/c1-26(2,15-19-9-6-7-10-20(19)16-27)25-31-18-22(11-4-3-5-13-23(29)30)24(32-25)21-12-8-14-28-17-21/h3-4,6-10,12,14,17,22,24-25H,5,11,13,15,18H2,1-2H3,(H,29,30)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036360 ((Z)-6-{2-[1-Methyl-1-(4-methylsulfanyl-phenoxy)-et...) Show SMILES CSc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)cc1 Show InChI InChI=1S/C25H31NO5S/c1-25(2,31-20-11-13-21(32-3)14-12-20)24-29-17-19(8-5-4-6-10-22(27)28)23(30-24)18-9-7-15-26-16-18/h4-5,7,9,11-16,19,23-24H,6,8,10,17H2,1-3H3,(H,27,28)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036374 ((Z)-6-[2-(4-Nitro-phenyl)-4-pyridin-3-yl-[1,3]diox...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22N2O6/c24-19(25)7-3-1-2-5-17-14-28-21(15-8-10-18(11-9-15)23(26)27)29-20(17)16-6-4-12-22-13-16/h1-2,4,6,8-13,17,20-21H,3,5,7,14H2,(H,24,25)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036390 ((Z)-6-[2-(1-Methyl-1-phenylsulfanyl-ethyl)-4-pyrid...) Show SMILES CC(C)(Sc1ccccc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C24H29NO4S/c1-24(2,30-20-12-6-4-7-13-20)23-28-17-19(10-5-3-8-14-21(26)27)22(29-23)18-11-9-15-25-16-18/h3-7,9,11-13,15-16,19,22-23H,8,10,14,17H2,1-2H3,(H,26,27)/b5-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036391 ((Z)-6-[2-(1-Benzenesulfonyl-1-methyl-ethyl)-4-pyri...) Show SMILES CC(C)(C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C24H29NO6S/c1-24(2,32(28,29)20-12-6-4-7-13-20)23-30-17-19(10-5-3-8-14-21(26)27)22(31-23)18-11-9-15-25-16-18/h3-7,9,11-13,15-16,19,22-23H,8,10,14,17H2,1-2H3,(H,26,27)/b5-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036383 ((Z)-6-{2-[1-(2-Cyano-phenylsulfanyl)-1-methyl-ethy...) Show SMILES CC(C)(Sc1ccccc1C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H28N2O4S/c1-25(2,32-21-12-7-6-9-18(21)15-26)24-30-17-20(10-4-3-5-13-22(28)29)23(31-24)19-11-8-14-27-16-19/h3-4,6-9,11-12,14,16,20,23-24H,5,10,13,17H2,1-2H3,(H,28,29)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036367 ((Z)-6-{2-[1-(4-Methoxy-2-nitro-phenylsulfanyl)-1-m...) Show SMILES COc1ccc(SC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C25H30N2O7S/c1-25(2,35-21-12-11-19(32-3)14-20(21)27(30)31)24-33-16-18(8-5-4-6-10-22(28)29)23(34-24)17-9-7-13-26-15-17/h4-5,7,9,11-15,18,23-24H,6,8,10,16H2,1-3H3,(H,28,29)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036366 ((Z)-6-(2-Naphthalen-1-yl-4-pyridin-3-yl-[1,3]dioxa...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1cccc2ccccc12 Show InChI InChI=1S/C25H25NO4/c27-23(28)14-3-1-2-9-20-17-29-25(30-24(20)19-11-7-15-26-16-19)22-13-6-10-18-8-4-5-12-21(18)22/h1-2,4-8,10-13,15-16,20,24-25H,3,9,14,17H2,(H,27,28)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034766 ((Z)-2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-4-...) Show SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)C(CCC\C=C(\c1ccccc1)c1cccnc1)C(O)=O Show InChI InChI=1S/C34H37NO7/c36-30-19-10-9-17-28(30)32-26(14-5-2-6-20-31(37)38)23-41-34(42-32)29(33(39)40)18-8-7-16-27(24-12-3-1-4-13-24)25-15-11-21-35-22-25/h1-5,9-13,15-17,19,21-22,26,29,32,34,36H,6-8,14,18,20,23H2,(H,37,38)(H,39,40)/b5-2-,27-16-/t26-,29?,32+,34+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034760 ((E)-7-(4-{10-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-e...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCCCCCCCCCC[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C44H57NO8/c46-40-22-15-14-21-39(40)44-36(18-9-7-11-23-41(47)48)33-52-43(53-44)25-13-5-3-1-2-4-6-16-31-51-37-28-26-34(27-29-37)38(35-19-17-30-45-32-35)20-10-8-12-24-42(49)50/h7,9,14-15,17,19-22,26-30,32,36,43-44,46H,1-6,8,10-13,16,18,23-25,31,33H2,(H,47,48)(H,49,50)/b9-7-,38-20+/t36-,43+,44+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034755 ((E)-7-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(cc1)[C@H]1OC[C@@H](C\C=C/CCC(O)=O)[C@H](O1)c1ccccc1O)c1cccnc1 Show InChI InChI=1S/C34H37NO7/c36-30-14-8-7-13-29(30)33-27(10-3-1-5-15-31(37)38)23-41-34(42-33)25-19-17-24(18-20-25)28(26-11-9-21-35-22-26)12-4-2-6-16-32(39)40/h1,3,7-9,11-14,17-22,27,33-34,36H,2,4-6,10,15-16,23H2,(H,37,38)(H,39,40)/b3-1-,28-12+/t27-,33+,34+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034753 ((E)-7-(4-{3-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCc2cccc(c2)[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C41H43NO8/c43-37-17-8-7-16-36(37)40-33(12-3-1-5-18-38(44)45)28-49-41(50-40)31-13-9-11-29(25-31)27-48-34-22-20-30(21-23-34)35(32-14-10-24-42-26-32)15-4-2-6-19-39(46)47/h1,3,7-11,13-17,20-26,33,40-41,43H,2,4-6,12,18-19,27-28H2,(H,44,45)(H,46,47)/b3-1-,35-15+/t33-,40+,41+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034748 ((E)-7-[4-(2-{3-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCCOc2cccc(c2)[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1 Show InChI InChI=1S/C42H45NO9/c44-38-17-8-7-16-37(38)41-33(11-3-1-5-18-39(45)46)29-51-42(52-41)31-12-9-14-35(27-31)50-26-25-49-34-22-20-30(21-23-34)36(32-13-10-24-43-28-32)15-4-2-6-19-40(47)48/h1,3,7-10,12-17,20-24,27-28,33,41-42,44H,2,4-6,11,18-19,25-26,29H2,(H,45,46)(H,47,48)/b3-1-,36-15+/t33-,41+,42+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50034744 (3-(6-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...) Show SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccc(OCCCCCCOc2cc(ccc2OCCn2ccnc2)C(O)=O)cc1 Show InChI InChI=1S/C40H46N2O10/c43-34-12-7-6-11-33(34)38-31(10-4-3-5-13-37(44)45)27-51-40(52-38)29-14-17-32(18-15-29)48-23-8-1-2-9-24-49-36-26-30(39(46)47)16-19-35(36)50-25-22-42-21-20-41-28-42/h3-4,6-7,11-12,14-21,26,28,31,38,40,43H,1-2,5,8-10,13,22-25,27H2,(H,44,45)(H,46,47)/b4-3-/t31-,38+,40+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase.				J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036381 ((Z)-6-{2-[1-(4-Methoxy-phenoxy)-1-methyl-ethyl]-4-...) Show SMILES COc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)cc1 Show InChI InChI=1S/C25H31NO6/c1-25(2,32-21-13-11-20(29-3)12-14-21)24-30-17-19(8-5-4-6-10-22(27)28)23(31-24)18-9-7-15-26-16-18/h4-5,7,9,11-16,19,23-24H,6,8,10,17H2,1-3H3,(H,27,28)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036363 ((Z)-6-[2-(3,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H21Cl2NO4/c22-17-9-8-14(11-18(17)23)21-27-13-16(5-2-1-3-7-19(25)26)20(28-21)15-6-4-10-24-12-15/h1-2,4,6,8-12,16,20-21H,3,5,7,13H2,(H,25,26)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036376 ((Z)-6-[2-(2,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H21Cl2NO4/c22-16-8-9-17(18(23)11-16)21-27-13-15(5-2-1-3-7-19(25)26)20(28-21)14-6-4-10-24-12-14/h1-2,4,6,8-12,15,20-21H,3,5,7,13H2,(H,25,26)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036347 ((Z)-6-[4-Pyridin-3-yl-2-(4-trifluoromethyl-phenyl)...) Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H22F3NO4/c23-22(24,25)18-10-8-15(9-11-18)21-29-14-17(5-2-1-3-7-19(27)28)20(30-21)16-6-4-12-26-13-16/h1-2,4,6,8-13,17,20-21H,3,5,7,14H2,(H,27,28)/b2-1-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036344 ((Z)-6-{2-[1-(2-Methanesulfonyl-phenoxy)-1-methyl-e...) Show SMILES CC(C)(Oc1ccccc1S(C)(=O)=O)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H31NO7S/c1-25(2,33-20-12-7-8-13-21(20)34(3,29)30)24-31-17-19(10-5-4-6-14-22(27)28)23(32-24)18-11-9-15-26-16-18/h4-5,7-9,11-13,15-16,19,23-24H,6,10,14,17H2,1-3H3,(H,27,28)/b5-4-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036351 ((Z)-6-{2-[1-(2-Cyano-phenoxy)-1-methyl-ethyl]-4-py...) Show SMILES CC(C)(Oc1ccccc1C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H28N2O5/c1-25(2,32-21-12-7-6-9-18(21)15-26)24-30-17-20(10-4-3-5-13-22(28)29)23(31-24)19-11-8-14-27-16-19/h3-4,6-9,11-12,14,16,20,23-24H,5,10,13,17H2,1-2H3,(H,28,29)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50036359 ((Z)-6-{2-[2-(4-Fluoro-phenyl)-1,1-dimethyl-ethyl]-...) Show SMILES CC(C)(Cc1ccc(F)cc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1 Show InChI InChI=1S/C25H30FNO4/c1-25(2,15-18-10-12-21(26)13-11-18)24-30-17-20(7-4-3-5-9-22(28)29)23(31-24)19-8-6-14-27-16-19/h3-4,6,8,10-14,16,20,23-24H,5,7,9,15,17H2,1-2H3,(H,28,29)/b4-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes				J Med Chem 38: 686-94 (1995) BindingDB Entry DOI: 10.7270/Q24Q7T2K
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 191 total )  |  Next  |  Last  >>

Jump to: