Compile Data Set for Download or QSAR

Found 221 hits with Last Name = 'caliandro' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.0960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029095 (CHEMBL3343300) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C40H50ClN3O14S/c1-22(2)44-15-13-27(14-16-44)39(49)42-35-29(9-7-10-30(35)53-20-28-19-31(58-43-28)33-11-12-34(41)59-33)50-17-8-18-51-40-38(56-26(6)48)37(55-25(5)47)36(54-24(4)46)32(57-40)21-52-23(3)45/h7,9-12,19,22,27,32,36-38,40H,8,13-18,20-21H2,1-6H3,(H,42,49)/t32-,36-,37+,38-,40-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Aldo Moro Curated by ChEMBL					Assay Description Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's method				ACS Med Chem Lett 11: 869-876 (2020) Article DOI: 10.1021/acsmedchemlett.9b00656 BindingDB Entry DOI: 10.7270/Q2WS8XS4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prothrombin (Bos taurus (Bovine))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50540764 (CHEMBL4648322) Show SMILES COc1cc2cc(NC(=O)[C@@H]3CCC[C@@H](C3)NCc3ccccc3)c(=O)oc2cc1OC |r| Show InChI InChI=1S/C25H28N2O5/c1-30-22-13-18-12-20(25(29)32-21(18)14-23(22)31-2)27-24(28)17-9-6-10-19(11-17)26-15-16-7-4-3-5-8-16/h3-5,7-8,12-14,17,19,26H,6,9-11,15H2,1-2H3,(H,27,28)/t17-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Aldo Moro Curated by ChEMBL					Assay Description Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's method				ACS Med Chem Lett 11: 869-876 (2020) Article DOI: 10.1021/acsmedchemlett.9b00656 BindingDB Entry DOI: 10.7270/Q2WS8XS4
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442069 (CHEMBL2441037) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1OC Show InChI InChI=1S/C26H29N3O4/c1-31-24-7-6-19(16-25(24)32-2)18-33-23-5-3-4-21(17-23)28-26(30)20-10-14-29(15-11-20)22-8-12-27-13-9-22/h3-9,12-13,16-17,20H,10-11,14-15,18H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442073 (CHEMBL2441035) Show SMILES O=C(Nc1cccc(OCc2ccc3OCOc3c2)c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H25N3O4/c29-25(19-8-12-28(13-9-19)21-6-10-26-11-7-21)27-20-2-1-3-22(15-20)30-16-18-4-5-23-24(14-18)32-17-31-23/h1-7,10-11,14-15,19H,8-9,12-13,16-17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442070 (CHEMBL2441054) Show SMILES Fc1cc(F)cc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H23F2N3O2/c25-19-12-17(13-20(26)14-19)16-31-23-3-1-2-21(15-23)28-24(30)18-6-10-29(11-7-18)22-4-8-27-9-5-22/h1-5,8-9,12-15,18H,6-7,10-11,16H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442071 (CHEMBL2441055) Show SMILES Fc1ccccc1COc1cccc(NC(=O)C2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-23-7-2-1-4-19(23)17-30-22-6-3-5-20(16-22)27-24(29)18-10-14-28(15-11-18)21-8-12-26-13-9-21/h1-9,12-13,16,18H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442074 (CHEMBL2441036) Show SMILES COc1cc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc(OC)c1 Show InChI InChI=1S/C26H29N3O4/c1-31-24-14-19(15-25(17-24)32-2)18-33-23-5-3-4-21(16-23)28-26(30)20-8-12-29(13-9-20)22-6-10-27-11-7-22/h3-7,10-11,14-17,20H,8-9,12-13,18H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50424045 (CHEMBL2314726) Show SMILES COc1cc2cc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccccc3)c(=O)oc2cc1OC |r| Show InChI InChI=1S/C25H28N2O5/c1-30-22-13-18-12-20(25(29)32-21(18)14-23(22)31-2)27-24(28)17-9-6-10-19(11-17)26-15-16-7-4-3-5-8-16/h3-5,7-8,12-14,17,19,26H,6,9-11,15H2,1-2H3,(H,27,28)/t17-,19+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Aldo Moro Curated by ChEMBL					Assay Description Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's method				ACS Med Chem Lett 11: 869-876 (2020) Article DOI: 10.1021/acsmedchemlett.9b00656 BindingDB Entry DOI: 10.7270/Q2WS8XS4
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50424045 (CHEMBL2314726) Show SMILES COc1cc2cc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccccc3)c(=O)oc2cc1OC |r| Show InChI InChI=1S/C25H28N2O5/c1-30-22-13-18-12-20(25(29)32-21(18)14-23(22)31-2)27-24(28)17-9-6-10-19(11-17)26-15-16-7-4-3-5-8-16/h3-5,7-8,12-14,17,19,26H,6,9-11,15H2,1-2H3,(H,27,28)/t17-,19+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Aldo Moro Curated by ChEMBL					Assay Description Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's method				ACS Med Chem Lett 11: 869-876 (2020) Article DOI: 10.1021/acsmedchemlett.9b00656 BindingDB Entry DOI: 10.7270/Q2WS8XS4
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442075 (CHEMBL2441047) Show SMILES CS(=O)(=O)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H27N3O4S/c1-33(30,31)24-7-5-19(6-8-24)18-32-23-4-2-3-21(17-23)27-25(29)20-11-15-28(16-12-20)22-9-13-26-14-10-22/h2-10,13-14,17,20H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442079 (CHEMBL2441033) Show SMILES Fc1ccc(CCOc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H26FN3O2/c26-21-6-4-19(5-7-21)12-17-31-24-3-1-2-22(18-24)28-25(30)20-10-15-29(16-11-20)23-8-13-27-14-9-23/h1-9,13-14,18,20H,10-12,15-17H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442093 (CHEMBL2441053) Show SMILES Clc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029095 (CHEMBL3343300) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C40H50ClN3O14S/c1-22(2)44-15-13-27(14-16-44)39(49)42-35-29(9-7-10-30(35)53-20-28-19-31(58-43-28)33-11-12-34(41)59-33)50-17-8-18-51-40-38(56-26(6)48)37(55-25(5)47)36(54-24(4)46)32(57-40)21-52-23(3)45/h7,9-12,19,22,27,32,36-38,40H,8,13-18,20-21H2,1-6H3,(H,42,49)/t32-,36-,37+,38-,40-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442072 (CHEMBL2441058) Show SMILES Fc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442094 (CHEMBL2441052) Show SMILES Clc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442069 (CHEMBL2441037) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1OC Show InChI InChI=1S/C26H29N3O4/c1-31-24-7-6-19(16-25(24)32-2)18-33-23-5-3-4-21(17-23)28-26(30)20-10-14-29(15-11-20)22-8-12-27-13-9-22/h3-9,12-13,16-17,20H,10-11,14-15,18H2,1-2H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	606	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442078 (CHEMBL2441030) Show SMILES Fc1ccc(OCc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-6-23(7-5-20)30-17-18-2-1-3-21(16-18)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	774	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442072 (CHEMBL2441058) Show SMILES Fc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442081 (CHEMBL2441039) Show SMILES COc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C25H27N3O3/c1-30-23-6-2-4-19(16-23)18-31-24-7-3-5-21(17-24)27-25(29)20-10-14-28(15-11-20)22-8-12-26-13-9-22/h2-9,12-13,16-17,20H,10-11,14-15,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442080 (CHEMBL2441040) Show SMILES COc1ccccc1COc1cccc(NC(=O)C2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C25H27N3O3/c1-30-24-8-3-2-5-20(24)18-31-23-7-4-6-21(17-23)27-25(29)19-11-15-28(16-12-19)22-9-13-26-14-10-22/h2-10,13-14,17,19H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442092 (CHEMBL2441051) Show SMILES Brc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24BrN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442082 (CHEMBL2441038) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H27N3O3/c1-30-23-7-5-19(6-8-23)18-31-24-4-2-3-21(17-24)27-25(29)20-11-15-28(16-12-20)22-9-13-26-14-10-22/h2-10,13-14,17,20H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442065 (CHEMBL2441032) Show SMILES Fc1cccc(CCOc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C25H26FN3O2/c26-21-4-1-3-19(17-21)11-16-31-24-6-2-5-22(18-24)28-25(30)20-9-14-29(15-10-20)23-7-12-27-13-8-23/h1-8,12-13,17-18,20H,9-11,14-16H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442086 (CHEMBL2441044) Show SMILES FC(F)(F)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H24F3N3O2/c26-25(27,28)20-6-4-18(5-7-20)17-33-23-3-1-2-21(16-23)30-24(32)19-10-14-31(15-11-19)22-8-12-29-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442076 (CHEMBL2441029) Show SMILES Fc1ccc(CCc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H26FN3O/c26-22-8-6-19(7-9-22)4-5-20-2-1-3-23(18-20)28-25(30)21-12-16-29(17-13-21)24-10-14-27-15-11-24/h1-3,6-11,14-15,18,21H,4-5,12-13,16-17H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442073 (CHEMBL2441035) Show SMILES O=C(Nc1cccc(OCc2ccc3OCOc3c2)c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H25N3O4/c29-25(19-8-12-28(13-9-19)21-6-10-26-11-7-21)27-20-2-1-3-22(15-20)30-16-18-4-5-23-24(14-18)32-17-31-23/h1-7,10-11,14-15,19H,8-9,12-13,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442067 (CHEMBL2441027) Show SMILES Fc1cccc(COc2cccc(NCC3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H26FN3O/c25-21-4-1-3-20(15-21)18-29-24-6-2-5-22(16-24)27-17-19-9-13-28(14-10-19)23-7-11-26-12-8-23/h1-8,11-12,15-16,19,27H,9-10,13-14,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442079 (CHEMBL2441033) Show SMILES Fc1ccc(CCOc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H26FN3O2/c26-21-6-4-19(5-7-21)12-17-31-24-3-1-2-22(18-24)28-25(30)20-10-15-29(16-11-20)23-8-13-27-14-9-23/h1-9,13-14,18,20H,10-12,15-17H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442095 (CHEMBL2441056) Show SMILES Fc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c(F)c1 Show InChI InChI=1S/C24H23F2N3O2/c25-19-5-4-18(23(26)14-19)16-31-22-3-1-2-20(15-22)28-24(30)17-8-12-29(13-9-17)21-6-10-27-11-7-21/h1-7,10-11,14-15,17H,8-9,12-13,16H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442090 (CHEMBL2441049) Show SMILES [O-][N+](=O)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24N4O4/c29-24(19-10-14-27(15-11-19)21-8-12-25-13-9-21)26-20-2-1-3-23(16-20)32-17-18-4-6-22(7-5-18)28(30)31/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442090 (CHEMBL2441049) Show SMILES [O-][N+](=O)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24N4O4/c29-24(19-10-14-27(15-11-19)21-8-12-25-13-9-21)26-20-2-1-3-23(16-20)32-17-18-4-6-22(7-5-18)28(30)31/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442091 (CHEMBL2441050) Show SMILES Brc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24BrN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine alpha-chymotrypsin using N-succinyl-Ala-Ala-Pro-Phe-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442062 (CHEMBL2441025) Show SMILES Fc1cccc(COc2ccc(NC(=O)C3CCN(CC3)c3ccncc3)cc2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-3-1-2-18(16-20)17-30-23-6-4-21(5-7-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442089 (CHEMBL2441048) Show SMILES [O-][N+](=O)c1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24N4O4/c29-24(19-9-13-27(14-10-19)21-7-11-25-12-8-21)26-20-4-2-6-23(16-20)32-17-18-3-1-5-22(15-18)28(30)31/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442071 (CHEMBL2441055) Show SMILES Fc1ccccc1COc1cccc(NC(=O)C2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-23-7-2-1-4-19(23)17-30-22-6-3-5-20(16-22)27-24(29)18-10-14-28(15-11-18)21-8-12-26-13-9-21/h1-9,12-13,16,18H,10-11,14-15,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029092 (CHEMBL3343304) Show SMILES Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C23H27ClN2O9S/c24-18-6-5-17(36-18)15-9-12(26-35-15)11-33-14-4-1-3-13(19(14)25)31-7-2-8-32-23-22(30)21(29)20(28)16(10-27)34-23/h1,3-6,9,16,20-23,27-30H,2,7-8,10-11,25H2/t16-,20-,21+,22-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442081 (CHEMBL2441039) Show SMILES COc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C25H27N3O3/c1-30-23-6-2-4-19(16-23)18-31-24-7-3-5-21(17-24)27-25(29)20-10-14-28(15-11-20)22-8-12-26-13-9-22/h2-9,12-13,16-17,20H,10-11,14-15,18H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442096 (CHEMBL2441060) Show SMILES O=C(Nc1cccc(OCc2ccccc2)c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c28-24(20-11-15-27(16-12-20)22-9-13-25-14-10-22)26-21-7-4-8-23(17-21)29-18-19-5-2-1-3-6-19/h1-10,13-14,17,20H,11-12,15-16,18H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair

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