Found 14 hits with Last Name = 'campbell' and Initial = 'ct' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255518
(4-(3,4-dichlorophenylamino)-7-methoxy-6-(4-methylp...)Show SMILES COc1cc2ncc(C(N)=O)c(Nc3ccc(Cl)c(Cl)c3)c2cc1N1CCN(C)CC1 Show InChI InChI=1S/C22H23Cl2N5O2/c1-28-5-7-29(8-6-28)19-10-14-18(11-20(19)31-2)26-12-15(22(25)30)21(14)27-13-3-4-16(23)17(24)9-13/h3-4,9-12H,5-8H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255517
(4-(2,4-dichlorophenylamino)-7-methoxy-6-(4-methylp...)Show SMILES COc1cc2ncc(C(N)=O)c(Nc3ccc(Cl)cc3Cl)c2cc1N1CCN(C)CC1 Show InChI InChI=1S/C22H23Cl2N5O2/c1-28-5-7-29(8-6-28)19-10-14-18(11-20(19)31-2)26-12-15(22(25)30)21(14)27-17-4-3-13(23)9-16(17)24/h3-4,9-12H,5-8H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255594
(4-(2,3-dichlorophenylamino)-7-fluoro-6-(4-methylpi...)Show SMILES CN1CCN(CC1)c1cc2c(Nc3cccc(Cl)c3Cl)c(cnc2cc1F)C(N)=O Show InChI InChI=1S/C21H20Cl2FN5O/c1-28-5-7-29(8-6-28)18-9-12-17(10-15(18)24)26-11-13(21(25)30)20(12)27-16-4-2-3-14(22)19(16)23/h2-4,9-11H,5-8H2,1H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255520
(4-(2,4-difluorophenylamino)-7-methoxy-6-(4-methylp...)Show SMILES COc1cc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2cc1N1CCN(C)CC1 Show InChI InChI=1S/C22H23F2N5O2/c1-28-5-7-29(8-6-28)19-10-14-18(11-20(19)31-2)26-12-15(22(25)30)21(14)27-17-4-3-13(23)9-16(17)24/h3-4,9-12H,5-8H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255811
(4-(2,4-difluorophenylamino)-7-ethoxy-6-(4-methylpi...)Show SMILES CCOc1cc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H25F2N5O2/c1-3-32-21-12-19-15(11-20(21)30-8-6-29(2)7-9-30)22(16(13-27-19)23(26)31)28-18-5-4-14(24)10-17(18)25/h4-5,10-13H,3,6-9H2,1-2H3,(H2,26,31)(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255592
(4-(2,3-dichlorophenylamino)-6-(4-methylpiperazin-1...)Show SMILES CN1CCN(CC1)c1ccc2ncc(C(N)=O)c(Nc3cccc(Cl)c3Cl)c2c1 Show InChI InChI=1S/C21H21Cl2N5O/c1-27-7-9-28(10-8-27)13-5-6-17-14(11-13)20(15(12-25-17)21(24)29)26-18-4-2-3-16(22)19(18)23/h2-6,11-12H,7-10H2,1H3,(H2,24,29)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255649
(4-(2,4-difluorophenylamino)-6-methoxy-7-(4-methylp...)Show SMILES COc1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1N1CCN(C)CC1)C(N)=O Show InChI InChI=1S/C22H23F2N5O2/c1-28-5-7-29(8-6-28)19-11-18-14(10-20(19)31-2)21(15(12-26-18)22(25)30)27-17-4-3-13(23)9-16(17)24/h3-4,9-12H,5-8H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255648
(4-(2,3-dichlorophenylamino)-6-methoxy-7-(4-methylp...)Show SMILES COc1cc2c(Nc3cccc(Cl)c3Cl)c(cnc2cc1N1CCN(C)CC1)C(N)=O Show InChI InChI=1S/C22H23Cl2N5O2/c1-28-6-8-29(9-7-28)18-11-17-13(10-19(18)31-2)21(14(12-26-17)22(25)30)27-16-5-3-4-15(23)20(16)24/h3-5,10-12H,6-9H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255647
(4-(3,4-dichlorophenylamino)-6-methoxy-7-(4-methylp...)Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)c(cnc2cc1N1CCN(C)CC1)C(N)=O Show InChI InChI=1S/C22H23Cl2N5O2/c1-28-5-7-29(8-6-28)19-11-18-14(10-20(19)31-2)21(15(12-26-18)22(25)30)27-13-3-4-16(23)17(24)9-13/h3-4,9-12H,5-8H2,1-2H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255418
(4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline...)Show InChI InChI=1S/C18H15F2N3O3/c1-25-15-6-10-14(7-16(15)26-2)22-8-11(18(21)24)17(10)23-13-4-3-9(19)5-12(13)20/h3-8H,1-2H3,(H2,21,24)(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255646
(4-(2,4-difluorophenylamino)-7-fluoro-6-(4-methylpi...)Show SMILES CN1CCN(CC1)c1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1F)C(N)=O Show InChI InChI=1S/C21H20F3N5O/c1-28-4-6-29(7-5-28)19-9-13-18(10-16(19)24)26-11-14(21(25)30)20(13)27-17-3-2-12(22)8-15(17)23/h2-3,8-11H,4-7H2,1H3,(H2,25,30)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255591
(4-(3,4-dichlorophenylamino)-6-(4-methylpiperazin-1...)Show SMILES CN1CCN(CC1)c1ccc2ncc(C(N)=O)c(Nc3ccc(Cl)c(Cl)c3)c2c1 Show InChI InChI=1S/C21H21Cl2N5O/c1-27-6-8-28(9-7-27)14-3-5-19-15(11-14)20(16(12-25-19)21(24)29)26-13-2-4-17(22)18(23)10-13/h2-5,10-12H,6-9H2,1H3,(H2,24,29)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255593
(4-(2,4-difluorophenylamino)-6-(4-methylpiperazin-1...)Show SMILES CN1CCN(CC1)c1ccc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2c1 Show InChI InChI=1S/C21H21F2N5O/c1-27-6-8-28(9-7-27)14-3-5-18-15(11-14)20(16(12-25-18)21(24)29)26-19-4-2-13(22)10-17(19)23/h2-5,10-12H,6-9H2,1H3,(H2,24,29)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50255590
(4-(2,4-dichlorophenylamino)-6-(4-methylpiperazin-1...)Show SMILES CN1CCN(CC1)c1ccc2ncc(C(N)=O)c(Nc3ccc(Cl)cc3Cl)c2c1 Show InChI InChI=1S/C21H21Cl2N5O/c1-27-6-8-28(9-7-27)14-3-5-18-15(11-14)20(16(12-25-18)21(24)29)26-19-4-2-13(22)10-17(19)23/h2-5,10-12H,6-9H2,1H3,(H2,24,29)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R (unknown origin) |
Bioorg Med Chem Lett 19: 701-5 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV |
More data for this
Ligand-Target Pair | |
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