Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 20 mins followed by ... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239467 (CHEMBL4086165) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of TMEM16A (unknown origin) expressed in Xenopus laevis oocytes at -60 mV holding potential by voltage-clamp assay | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Binding affinity to B-RAF kinase (unknown origin) | Eur J Med Chem 81: 427-41 (2014) Article DOI: 10.1016/j.ejmech.2014.05.025 BindingDB Entry DOI: 10.7270/Q2K075VT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Competitive inhibition of recombinant B-Raf (unknown origin) expressed in HEK293 cells by FRET analysis in presence of ATP | Bioorg Med Chem Lett 25: 4287-92 (2015) Article DOI: 10.1016/j.bmcl.2015.07.082 BindingDB Entry DOI: 10.7270/Q2J9686Z | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239433 (CHEMBL3134585) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Competitive binding affinity to B-RAF kinase (unknown origin) after 60 to 120 mins by FRET analysis | Eur J Med Chem 81: 427-41 (2014) Article DOI: 10.1016/j.ejmech.2014.05.025 BindingDB Entry DOI: 10.7270/Q2K075VT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239428 (CHEMBL4104024) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575379 (CHEMBL4852814) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239446 (CHEMBL4069503) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239457 (CHEMBL4071143) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575376 (CHEMBL4854119) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239447 (CHEMBL4090522) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239470 (CHEMBL4095338) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239461 (CHEMBL4074900) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239457 (CHEMBL4071143) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239426 (CHEMBL1444023) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575413 (CHEMBL4877679) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239433 (CHEMBL3134585) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575384 (CHEMBL4866473) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239438 (CHEMBL4099581) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239475 (CHEMBL4082703) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239469 (CHEMBL4091961) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239458 (CHEMBL4095365) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575409 (CHEMBL4863725) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-2 (Homo sapiens) | BDBM50239457 (CHEMBL4071143) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-2 (Homo sapiens) | BDBM50239459 (CHEMBL4074929) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575378 (CHEMBL4849241) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575404 (CHEMBL4863558) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239426 (CHEMBL1444023) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239463 (CHEMBL4087641) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239448 (CHEMBL4080209) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575383 (CHEMBL4849781) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575377 (CHEMBL4874714) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575387 (CHEMBL4848036) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239464 (CHEMBL4085154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575382 (CHEMBL4864461) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239428 (CHEMBL4104024) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239439 (CHEMBL4083154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575386 (CHEMBL4852450) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239430 (CHEMBL4096263) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239464 (CHEMBL4085154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575385 (CHEMBL4877290) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 1 (Rattus norvegicus (Rat)) | BDBM50575413 (CHEMBL4877679) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-B incubated for 15 mins | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575403 (CHEMBL4877908) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea transporter 2 (Rattus norvegicus (Rat)) | BDBM50575405 (CHEMBL4848692) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239462 (CHEMBL4066286) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239460 (CHEMBL4103095) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 925 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair |
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