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Compile Data Set for Download or QSAR

Found 149 hits with Last Name = 'dominy' and Initial = 'bw'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215854
PNG
(CHEMBL301829)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215854
PNG
(CHEMBL301829)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215854
PNG
(CHEMBL301829)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215738
PNG
(CHEMBL52675)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215740
PNG
(CHEMBL48906)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C29H23FO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215740
PNG
(CHEMBL48906)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C29H23FO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215855
PNG
(CHEMBL51467)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)cc(F)c1C(O)=O
Show InChI InChI=1S/C23H18F2O4/c24-16-10-18(21(23(27)28)19(25)11-16)14-6-7-17-20(9-14)29-12-15(22(17)26)8-13-4-2-1-3-5-13/h1-7,9-11,15,22,26H,8,12H2,(H,27,28)/t15-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215738
PNG
(CHEMBL52675)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215738
PNG
(CHEMBL52675)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50037218
PNG
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O
Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1
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n/an/a 5.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225831
PNG
(CHEMBL542376)
Show SMILES Cl.Fc1ccc(cc1)-n1c2CN(CCCCCCN3C(=O)CNC3=O)CCc2c2cc(F)ccc12
Show InChI InChI=1S/C26H28F2N4O2/c27-18-5-8-20(9-6-18)32-23-10-7-19(28)15-22(23)21-11-14-30(17-24(21)32)12-3-1-2-4-13-31-25(33)16-29-26(31)34/h5-10,15H,1-4,11-14,16-17H2,(H,29,34)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215853
PNG
(CHEMBL417364)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215853
PNG
(CHEMBL417364)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225783
PNG
(CHEMBL553243)
Show SMILES Cl.[H][C@]12CN(CCCCCN3C(=O)CNC3=O)CC[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1 |r|
Show InChI InChI=1S/C25H28F2N4O2.ClH/c26-17-4-7-19(8-5-17)31-22-9-6-18(27)14-21(22)20-10-13-29(16-23(20)31)11-2-1-3-12-30-24(32)15-28-25(30)33;/h4-9,14,20,23H,1-3,10-13,15-16H2,(H,28,33);1H/t20-,23+;/m1./s1
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n/an/a 6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50037218
PNG
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O
Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to inhibit [3H]LTB4 binding to LTB4 receptors on guinea pig spleen membranes


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225786
PNG
(CHEMBL417401)
Show SMILES [H][C@]12CCNC[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C17H16F2N2/c18-11-1-4-13(5-2-11)21-16-6-3-12(19)9-14(16)15-10-20-8-7-17(15)21/h1-6,9,15,17,20H,7-8,10H2/t15-,17+/m1/s1
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n/an/a 6.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215854
PNG
(CHEMBL301829)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225832
PNG
(CHEMBL539257)
Show SMILES Cl.CN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C18H18F2N2.ClH/c1-21-9-8-18-16(11-21)15-10-13(20)4-7-17(15)22(18)14-5-2-12(19)3-6-14;/h2-7,10,16,18H,8-9,11H2,1H3;1H
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215737
PNG
(CHEMBL50425)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215737
PNG
(CHEMBL50425)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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n/an/a 8n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50037218
PNG
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O
Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1
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n/an/a 8.40n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225784
PNG
(CHEMBL542375)
Show SMILES Cl.Fc1ccc(cc1)-n1c2CCN(CCCCCCNC(=O)c3ccccc3)Cc2c2cc(F)ccc12
Show InChI InChI=1S/C30H31F2N3O/c31-23-10-13-25(14-11-23)35-28-15-12-24(32)20-26(28)27-21-34(19-16-29(27)35)18-7-2-1-6-17-33-30(36)22-8-4-3-5-9-22/h3-5,8-15,20H,1-2,6-7,16-19,21H2,(H,33,36)
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n/an/a 8.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215739
PNG
(CHEMBL52374)
Show SMILES OCc1ccc(cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1)C(F)(F)F
Show InChI InChI=1S/C24H21F3O3/c25-24(26,27)19-8-6-17(13-28)21(12-19)16-7-9-20-22(11-16)30-14-18(23(20)29)10-15-4-2-1-3-5-15/h1-9,11-12,18,23,28-29H,10,13-14H2/t18-,23+/m0/s1
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n/an/a 9n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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TBA

Curated by ChEMBL


Assay Description
compound was tested for inhibition of 0.5 nM [3H]spiroperidol binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225839
PNG
(CHEMBL545436)
Show SMILES Cl.Fc1ccc(cc1)N1C2CN(CCCCCCN3C(=O)CNC3=O)CCC2c2cc(F)ccc12
Show InChI InChI=1S/C26H30F2N4O2.ClH/c27-18-5-8-20(9-6-18)32-23-10-7-19(28)15-22(23)21-11-14-30(17-24(21)32)12-3-1-2-4-13-31-25(33)16-29-26(31)34;/h5-10,15,21,24H,1-4,11-14,16-17H2,(H,29,34);1H
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n/an/a 9.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215861
PNG
(CHEMBL298724)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215861
PNG
(CHEMBL298724)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215861
PNG
(CHEMBL298724)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1
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n/an/a 11n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215738
PNG
(CHEMBL52675)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215738
PNG
(CHEMBL52675)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50221805
PNG
(CP-36584 | Flutroline)
Show SMILES OC(CCCN1CCc2c(C1)c1cc(F)ccc1n2-c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H25F3N2O/c28-19-5-3-18(4-6-19)27(33)2-1-14-31-15-13-26-24(17-31)23-16-21(30)9-12-25(23)32(26)22-10-7-20(29)8-11-22/h3-12,16,27,33H,1-2,13-15,17H2
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225790
PNG
(CHEMBL299903)
Show SMILES [H][C@]12CCN(CCCC(=O)NC3CCCCC3)C[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C27H33F2N3O/c28-19-8-11-22(12-9-19)32-25-13-10-20(29)17-23(25)24-18-31(16-14-26(24)32)15-4-7-27(33)30-21-5-2-1-3-6-21/h8-13,17,21,24,26H,1-7,14-16,18H2,(H,30,33)/t24-,26+/m1/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225829
PNG
(CHEMBL545209)
Show SMILES Cl.[H][C@]12CN(CCCCN3C(=O)CNC3=O)CC[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1 |r|
Show InChI InChI=1S/C24H26F2N4O2.ClH/c25-16-3-6-18(7-4-16)30-21-8-5-17(26)13-20(21)19-9-12-28(15-22(19)30)10-1-2-11-29-23(31)14-27-24(29)32;/h3-8,13,19,22H,1-2,9-12,14-15H2,(H,27,32);1H/t19-,22+;/m1./s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225777
PNG
(CHEMBL543327)
Show SMILES Cl.CC(=O)NCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C23H27F2N3O.ClH/c1-16(29)26-11-2-3-12-27-13-10-23-21(15-27)20-14-18(25)6-9-22(20)28(23)19-7-4-17(24)5-8-19;/h4-9,14,21,23H,2-3,10-13,15H2,1H3,(H,26,29);1H
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225834
PNG
(CHEMBL543095)
Show SMILES Cl.Fc1ccc(cc1)N1C2CCN(CCCCCCNC(=O)c3ccccc3)CC2c2cc(F)ccc12
Show InChI InChI=1S/C30H33F2N3O.ClH/c31-23-10-13-25(14-11-23)35-28-15-12-24(32)20-26(28)27-21-34(19-16-29(27)35)18-7-2-1-6-17-33-30(36)22-8-4-3-5-9-22;/h3-5,8-15,20,27,29H,1-2,6-7,16-19,21H2,(H,33,36);1H
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215741
PNG
(CHEMBL418264)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C23H19ClO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225775
PNG
(CHEMBL294488)
Show SMILES Fc1ccc(cc1)N1C2CN(CCCN3C(=O)CNC3=O)CCC2c2cc(F)ccc12
Show InChI InChI=1S/C23H24F2N4O2/c24-15-2-5-17(6-3-15)29-20-7-4-16(25)12-19(20)18-8-11-27(14-21(18)29)9-1-10-28-22(30)13-26-23(28)31/h2-7,12,18,21H,1,8-11,13-14H2,(H,26,31)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225778
PNG
(CHEMBL540282)
Show SMILES Cl.[H][C@]12CN(CCCCCCN3C(=O)CNC3=O)CC[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1 |r|
Show InChI InChI=1S/C26H30F2N4O2.ClH/c27-18-5-8-20(9-6-18)32-23-10-7-19(28)15-22(23)21-11-14-30(17-24(21)32)12-3-1-2-4-13-31-25(33)16-29-26(31)34;/h5-10,15,21,24H,1-4,11-14,16-17H2,(H,29,34);1H/t21-,24+;/m1./s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215868
PNG
(CHEMBL51535)
Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1
Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1
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n/an/a 17n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225842
PNG
(CHEMBL544039)
Show SMILES Cl.[H][C@]12CCN(CCCC(=O)Nc3ccccc3)C[C@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1 |r|
Show InChI InChI=1S/C27H27F2N3O.ClH/c28-19-8-11-22(12-9-19)32-25-13-10-20(29)17-23(25)24-18-31(16-14-26(24)32)15-4-7-27(33)30-21-5-2-1-3-6-21;/h1-3,5-6,8-13,17,24,26H,4,7,14-16,18H2,(H,30,33);1H/t24-,26+;/m1./s1
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n/an/a 19n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215859
PNG
(CHEMBL51775)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1-c1nn[nH]n1
Show InChI InChI=1S/C23H19FN4O2/c24-17-7-9-18(23-25-27-28-26-23)20(12-17)15-6-8-19-21(11-15)30-13-16(22(19)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,29H,10,13H2,(H,25,26,27,28)/t16-,22+/m0/s1
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n/an/a 20n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215861
PNG
(CHEMBL298724)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215861
PNG
(CHEMBL298724)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225776
PNG
(CHEMBL60634)
Show SMILES [H][C@@]12CCN(CCC[C@@H](O)c3ccc(F)cc3)C[C@@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C27H27F3N2O/c28-19-5-3-18(4-6-19)27(33)2-1-14-31-15-13-26-24(17-31)23-16-21(30)9-12-25(23)32(26)22-10-7-20(29)8-11-22/h3-12,16,24,26-27,33H,1-2,13-15,17H2/t24-,26+,27+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225776
PNG
(CHEMBL60634)
Show SMILES [H][C@@]12CCN(CCC[C@@H](O)c3ccc(F)cc3)C[C@@]1([H])c1cc(F)ccc1N2c1ccc(F)cc1
Show InChI InChI=1S/C27H27F3N2O/c28-19-5-3-18(4-6-19)27(33)2-1-14-31-15-13-26-24(17-31)23-16-21(30)9-12-25(23)32(26)22-10-7-20(29)8-11-22/h3-12,16,24,26-27,33H,1-2,13-15,17H2/t24-,26+,27+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215744
PNG
(CHEMBL299150)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(c1C(O)=O)C(F)(F)F
Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)19-8-4-7-17(21(19)23(29)30)15-9-10-18-20(12-15)31-13-16(22(18)28)11-14-5-2-1-3-6-14/h1-10,12,16,22,28H,11,13H2,(H,29,30)/t16-,22+/m0/s1
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n/an/a 24n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215743
PNG
(CHEMBL51219)
Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1ccc(F)cc1C(O)=O
Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(20(12-17)23(26)27)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1
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n/an/a 24n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50225838
PNG
(CHEMBL544036)
Show SMILES Cl.O[C@H](CCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)c1ccc(F)cc1 |r|
Show InChI InChI=1S/C27H27F3N2O.ClH/c28-19-5-3-18(4-6-19)27(33)2-1-14-31-15-13-26-24(17-31)23-16-21(30)9-12-25(23)32(26)22-10-7-20(29)8-11-22;/h3-12,16,24,26-27,33H,1-2,13-15,17H2;1H/t24?,26?,27-;/m1./s1
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n/an/a 25n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane.


J Med Chem 29: 8-19 (1986)


BindingDB Entry DOI: 10.7270/Q2NP26N5
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215737
PNG
(CHEMBL50425)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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n/an/a 26n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1/2


(Homo sapiens (Human))
BDBM50215737
PNG
(CHEMBL50425)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1
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n/an/a 26n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
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