Compile Data Set for Download or QSAR

Found 57 hits with Last Name = 'dubreuil' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50024328 (3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@H](CC(O)=O)NC(=O)C(Cc1ccccc1)C(N)=O Show InChI InChI=1S/C35H46N6O8/c1-20(2)15-26(33(47)41-28(18-29(42)43)40-31(45)24(30(36)44)16-21-11-7-6-8-12-21)38-32(46)27(39-34(48)49-35(3,4)5)17-22-19-37-25-14-10-9-13-23(22)25/h6-14,19-20,24,26-28,37H,15-18H2,1-5H3,(H2,36,44)(H,38,46)(H,39,48)(H,40,45)(H,41,47)(H,42,43)/t24?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity for binding of [125I]-(Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.				J Med Chem 30: 758-63 (1987) BindingDB Entry DOI: 10.7270/Q2CV4GRT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) Show SMILES CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1 Show InChI InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359981 (CHEMBL1927770) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359982 (CHEMBL1927771) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) Show SMILES CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1 Show InChI InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50024330 (3-(3-Benzyl-ureido)-3-{2-[2-tert-butoxycarbonylami...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C35H46N6O8/c1-20(2)15-26(31(45)40-28(18-29(42)43)33(47)38-25(30(36)44)16-21-11-7-6-8-12-21)39-32(46)27(41-34(48)49-35(3,4)5)17-22-19-37-24-14-10-9-13-23(22)24/h6-14,19-20,25-28,37H,15-18H2,1-5H3,(H2,36,44)(H,38,47)(H,39,46)(H,40,45)(H,41,48)(H,42,43)/t25-,26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity for binding of [125I]-(Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.				J Med Chem 30: 758-63 (1987) BindingDB Entry DOI: 10.7270/Q2CV4GRT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174413 (2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...) Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1 Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359981 (CHEMBL1927770) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Fibroblast growth factor receptor 3				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174413 (2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...) Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1 Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Fibroblast growth factor receptor 3				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359983 (CHEMBL1927769) Show SMILES Cc1cc(C)cc(CC(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C34H30N4O2S/c1-22-16-23(2)18-25(17-22)20-32(39)36-28(19-24-8-4-3-5-9-24)33(40)35-27-14-12-26(13-15-27)29-21-38-30-10-6-7-11-31(30)41-34(38)37-29/h3-18,21,28H,19-20H2,1-2H3,(H,35,40)(H,36,39)/t28-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174412 (9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...) Show SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359984 (CHEMBL1927768) Show SMILES Cc1cc(C)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C34H30N4O2S/c1-22-16-23(2)18-25(17-22)20-32(39)36-28(19-24-8-4-3-5-9-24)33(40)35-27-14-12-26(13-15-27)29-21-38-30-10-6-7-11-31(30)41-34(38)37-29/h3-18,21,28H,19-20H2,1-2H3,(H,35,40)(H,36,39)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	607	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359982 (CHEMBL1927771) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359985 (CHEMBL1927772) Show SMILES Fc1cc(F)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C32H24F2N4O2S/c33-23-14-21(15-24(34)18-23)17-30(39)36-26(16-20-6-2-1-3-7-20)31(40)35-25-12-10-22(11-13-25)27-19-38-28-8-4-5-9-29(28)41-32(38)37-27/h1-15,18-19,26H,16-17H2,(H,35,40)(H,36,39)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359986 (CHEMBL1927625) Show SMILES Cc1cc(C)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c4CCCCc4sc3n2)c1 |r| Show InChI InChI=1S/C34H34N4O2S/c1-22-16-23(2)18-25(17-22)20-32(39)36-28(19-24-8-4-3-5-9-24)33(40)35-27-14-12-26(13-15-27)29-21-38-30-10-6-7-11-31(30)41-34(38)37-29/h3-5,8-9,12-18,21,28H,6-7,10-11,19-20H2,1-2H3,(H,35,40)(H,36,39)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	793	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174412 (9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...) Show SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359981 (CHEMBL1927770) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	811	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359982 (CHEMBL1927771) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174410 (1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50024327 (CHEMBL349888 | N-{1-[2-tert-Butoxycarbonylamino-3-...) Show SMILES CC(C)C[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C(Cc1ccccc1)C(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C Show InChI InChI=1S/C35H46N6O8/c1-20(2)15-28(41-33(47)27(18-29(42)43)38-31(45)24(30(36)44)16-21-11-7-6-8-12-21)40-32(46)26(39-34(48)49-35(3,4)5)17-22-19-37-25-14-10-9-13-23(22)25/h6-14,19-20,24,26-28,37H,15-18H2,1-5H3,(H2,36,44)(H,38,45)(H,39,48)(H,40,46)(H,41,47)(H,42,43)/t24?,26-,27+,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity for binding of [125I]-(Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.				J Med Chem 30: 758-63 (1987) BindingDB Entry DOI: 10.7270/Q2CV4GRT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174410 (1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Fibroblast growth factor receptor 3				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) Show SMILES CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1 Show InChI InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359984 (CHEMBL1927768) Show SMILES Cc1cc(C)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C34H30N4O2S/c1-22-16-23(2)18-25(17-22)20-32(39)36-28(19-24-8-4-3-5-9-24)33(40)35-27-14-12-26(13-15-27)29-21-38-30-10-6-7-11-31(30)41-34(38)37-29/h3-18,21,28H,19-20H2,1-2H3,(H,35,40)(H,36,39)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174411 (CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12 Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174407 (CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174411 (CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12 Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174407 (CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359981 (CHEMBL1927770) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H24F6N4O2S/c35-33(36,37)23-14-21(15-24(18-23)34(38,39)40)17-30(45)42-26(16-20-6-2-1-3-7-20)31(46)41-25-12-10-22(11-13-25)27-19-44-28-8-4-5-9-29(28)47-32(44)43-27/h1-15,18-19,26H,16-17H2,(H,41,46)(H,42,45)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of TPR-fused MET-mediated mouse BA/F3 cell proliferation after 48 hrs by cell titre blue based spectrophotometry				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359985 (CHEMBL1927772) Show SMILES Fc1cc(F)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C32H24F2N4O2S/c33-23-14-21(15-24(34)18-23)17-30(39)36-26(16-20-6-2-1-3-7-20)31(40)35-25-12-10-22(11-13-25)27-19-38-28-8-4-5-9-29(28)41-32(38)37-27/h1-15,18-19,26H,16-17H2,(H,35,40)(H,36,39)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50024332 (3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@H](CC(O)=O)NC(=O)CCc1ccccc1 Show InChI InChI=1S/C34H45N5O7/c1-21(2)17-26(32(44)39-28(19-30(41)42)38-29(40)16-15-22-11-7-6-8-12-22)36-31(43)27(37-33(45)46-34(3,4)5)18-23-20-35-25-14-10-9-13-24(23)25/h6-14,20-21,26-28,35H,15-19H2,1-5H3,(H,36,43)(H,37,45)(H,38,40)(H,39,44)(H,41,42)/t26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity for binding of [125I]-(Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.				J Med Chem 30: 758-63 (1987) BindingDB Entry DOI: 10.7270/Q2CV4GRT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359987 (CHEMBL1927778) Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(Br)ccc32)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H23BrF6N4O2S/c35-24-8-11-28-29(17-24)48-32-44-27(18-45(28)32)21-6-9-25(10-7-21)42-31(47)26(14-19-4-2-1-3-5-19)43-30(46)15-20-12-22(33(36,37)38)16-23(13-20)34(39,40)41/h1-13,16-18,26H,14-15H2,(H,42,47)(H,43,46)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50359984 (CHEMBL1927768) Show SMILES Cc1cc(C)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1 |r| Show InChI InChI=1S/C34H30N4O2S/c1-22-16-23(2)18-25(17-22)20-32(39)36-28(19-24-8-4-3-5-9-24)33(40)35-27-14-12-26(13-15-27)29-21-38-30-10-6-7-11-31(30)41-34(38)37-29/h3-18,21,28H,19-20H2,1-2H3,(H,35,40)(H,36,39)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 6216 Curated by ChEMBL					Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...				Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174409 (9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...) Show SMILES Cc1c2[nH]c3ccc(Br)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50174409 (9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...) Show SMILES Cc1c2[nH]c3ccc(Br)cc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...) Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...) Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair

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