Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endoplasmin (Canis familiaris) | BDBM20732 ((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endoplasmin (Canis familiaris) | BDBM50439621 (GANETESPIB | STA-9090) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endoplasmin (Canis familiaris) | BDBM20926 (5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
o-succinylbenzoate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM181038 (OSB-AMS (1)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Argonne National Laboratory | Assay Description Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi... | Biochemistry 54: 6514-24 (2015) Article DOI: 10.1021/acs.biochem.5b00966 BindingDB Entry DOI: 10.7270/Q2RX99WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endoplasmin (Canis familiaris) | BDBM50180302 (8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endoplasmin (Canis familiaris) | BDBM15359 ((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock protein 75 kDa, mitochondrial (Homo sapiens (Human)) | BDBM20926 (5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock protein 75 kDa, mitochondrial (Homo sapiens (Human)) | BDBM50439621 (GANETESPIB | STA-9090) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a... | J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 21: This assay is based on a competitive binder which can interact with a latent pocket formed only in the inactive state of the kinase. A... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Tyrosine-protein kinase Fyn (T) (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 22: This assay referred to as FlashPlate-based Protein Kinase Assay uses recombinant protein kinase and ATP concentration corresponding to... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473176 (US10844038, Example 37 | US10844038, Example 38 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase CSK (Homo sapiens (Human)) | BDBM473171 ((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473184 (US10844038, Example 62 | trans 3-((4-Amino-3-(4-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM473185 (US10844038, Example 63 | trans 3-((4-Amino-3-(4-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn [Y531F] (Homo sapiens (Human)) | BDBM473174 ((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn [Y531F] (Homo sapiens (Human)) | BDBM473175 ((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn [Y531F] (Homo sapiens (Human)) | BDBM473172 ((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
SABILA BIOSCIENCES LLC US Patent | Assay Description IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ... | US Patent US10844038 (2020) BindingDB Entry DOI: 10.7270/Q25D8VZ7 | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 171 total ) | Next | Last >> |