Compile Data Set for Download or QSAR

Found 48 hits with Last Name = 'flatt' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM28529 (Azepino[4,5-b]indole, 1 | ethyl 3-[(4-fluorophenyl...) Show SMILES CCOC(=O)C1=CN(CCc2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:5| Show InChI InChI=1S/C22H19FN2O3/c1-2-28-22(27)18-13-25(21(26)14-7-9-15(23)10-8-14)12-11-17-16-5-3-4-6-19(16)24-20(17)18/h3-10,13,24H,2,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) Show SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bile acid receptor (Homo sapiens (Human))	BDBM28531 (Azepino[4,5-b]indole, 6b | propyl 3-[(4-fluorophen...) Show SMILES CCCOC(=O)C1=CN(CCc2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:6| Show InChI InChI=1S/C23H21FN2O3/c1-2-13-29-23(28)19-14-26(22(27)15-7-9-16(24)10-8-15)12-11-18-17-5-3-4-6-20(17)25-21(18)19/h3-10,14,25H,2,11-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28532 (Azepino[4,5-b]indole, 6c | butyl 3-[(4-fluoropheny...) Show SMILES CCCCOC(=O)C1=CN(CCc2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:7| Show InChI InChI=1S/C24H23FN2O3/c1-2-3-14-30-24(29)20-15-27(23(28)16-8-10-17(25)11-9-16)13-12-19-18-6-4-5-7-21(18)26-22(19)20/h4-11,15,26H,2-3,12-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28533 (Azepino[4,5-b]indole, 6d | ethyl 3-[(4-fluoropheny...) Show SMILES CCOC(=O)C1=CN(CC(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:5| Show InChI InChI=1S/C23H21FN2O3/c1-3-29-23(28)18-13-26(22(27)15-8-10-16(24)11-9-15)12-14(2)20-17-6-4-5-7-19(17)25-21(18)20/h4-11,13-14,25H,3,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28534 (Azepino[4,5-b]indole, 6e | ethyl 3-[(4-chloropheny...) Show SMILES CCOC(=O)C1=CN(CC(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(Cl)cc1 |t:5| Show InChI InChI=1S/C23H21ClN2O3/c1-3-29-23(28)18-13-26(22(27)15-8-10-16(24)11-9-15)12-14(2)20-17-6-4-5-7-19(17)25-21(18)20/h4-11,13-14,25H,3,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28535 (Azepino[4,5-b]indole, 6f | ethyl 3-[(4-methoxyphen...) Show SMILES CCOC(=O)C1=CN(CC(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(OC)cc1 |t:5| Show InChI InChI=1S/C24H24N2O4/c1-4-30-24(28)19-14-26(23(27)16-9-11-17(29-3)12-10-16)13-15(2)21-18-7-5-6-8-20(18)25-22(19)21/h5-12,14-15,25H,4,13H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28536 (Azepino[4,5-b]indole, 6g | ethyl 3-[(3,4-difluorop...) Show SMILES CCOC(=O)C1=CN(CC(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)c(F)c1 |t:5| Show InChI InChI=1S/C23H20F2N2O3/c1-3-30-23(29)16-12-27(22(28)14-8-9-17(24)18(25)10-14)11-13(2)20-15-6-4-5-7-19(15)26-21(16)20/h4-10,12-13,26H,3,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28537 (Azepino[4,5-b]indole, 6h | ethyl 3-[(4-fluoropheny...) Show SMILES CCOC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:5| Show InChI InChI=1S/C24H23FN2O3/c1-4-30-23(29)18-13-27(22(28)15-9-11-16(25)12-10-15)14-24(2,3)20-17-7-5-6-8-19(17)26-21(18)20/h5-13,26H,4,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28538 (Azepino[4,5-b]indole, 6i | FXR_5 | ethyl 3-[(3,4-d...) Show SMILES CCOC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)c(F)c1 |t:5| Show InChI InChI=1S/C24H22F2N2O3/c1-4-31-23(30)16-12-28(22(29)14-9-10-17(25)18(26)11-14)13-24(2,3)20-15-7-5-6-8-19(15)27-21(16)20/h5-12,27H,4,13H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28539 (Azepino[4,5-b]indole, 6j | ethyl 3-[(4-chloropheny...) Show SMILES CCOC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(Cl)cc1 |t:5| Show InChI InChI=1S/C24H23ClN2O3/c1-4-30-23(29)18-13-27(22(28)15-9-11-16(25)12-10-15)14-24(2,3)20-17-7-5-6-8-19(17)26-21(18)20/h5-13,26H,4,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28540 (Azepino[4,5-b]indole, 6k | ethyl 3-[(4-methoxyphen...) Show SMILES CCOC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(OC)cc1 |t:5| Show InChI InChI=1S/C25H26N2O4/c1-5-31-24(29)19-14-27(23(28)16-10-12-17(30-4)13-11-16)15-25(2,3)21-18-8-6-7-9-20(18)26-22(19)21/h6-14,26H,5,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28541 (Azepino[4,5-b]indole, 6l | propan-2-yl 3-[(4-fluor...) Show SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:6| Show InChI InChI=1S/C25H25FN2O3/c1-15(2)31-24(30)19-13-28(23(29)16-9-11-17(26)12-10-16)14-25(3,4)21-18-7-5-6-8-20(18)27-22(19)21/h5-13,15,27H,14H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28542 (WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...) Show SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)c(F)c1 |t:6| Show InChI InChI=1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034775 (CHEMBL3360975 | US10543183, Compound 38 | US109459...) Show SMILES CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034776 (CHEMBL3360974) Show SMILES CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C26H25ClN2O3S/c1-26(2,30)24-17-29(25(28-24)16-20-7-4-5-10-23(20)27)21-13-11-18(12-14-21)19-8-6-9-22(15-19)33(3,31)32/h4-15,17,30H,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034777 (CHEMBL3360973) Show SMILES CC(C)(O)c1cn(c(Cc2ccccc2C(F)(F)F)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C27H25F3N2O3S/c1-26(2,33)24-17-32(25(31-24)16-20-7-4-5-10-23(20)27(28,29)30)21-13-11-18(12-14-21)19-8-6-9-22(15-19)36(3,34)35/h4-15,17,33H,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034778 (CHEMBL3360972) Show SMILES CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O |(.07,-55.05,;1.6,-55.21,;2.22,-56.62,;.5,-56.3,;2.5,-53.97,;4.04,-53.97,;4.53,-52.5,;3.27,-51.6,;2.03,-52.51,;3.27,-50.06,;1.94,-49.3,;.61,-50.08,;1.93,-47.77,;3.27,-46.98,;4.61,-47.75,;4.61,-49.29,;6.09,-48.88,;5.84,-51.71,;7.18,-52.45,;8.5,-51.66,;8.47,-50.12,;7.12,-49.38,;5.8,-50.17,;9.79,-49.32,;11.14,-50.07,;12.45,-49.27,;12.42,-47.73,;11.06,-46.99,;9.75,-47.79,;11.02,-45.45,;12.34,-44.64,;9.53,-45.04,;10.62,-43.95,)| Show InChI InChI=1S/C25H22Cl2N2O3S/c1-25(2,30)22-15-29(24(28-22)23-20(26)8-5-9-21(23)27)18-12-10-16(11-13-18)17-6-4-7-19(14-17)33(3,31)32/h4-15,30H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034779 (CHEMBL3360971) Show SMILES CC(C)(O)c1cn(c(n1)-c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C25H23ClN2O3S/c1-25(2,29)23-16-28(24(27-23)21-9-4-5-10-22(21)26)19-13-11-17(12-14-19)18-7-6-8-20(15-18)32(3,30)31/h4-16,29H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034780 (CHEMBL3360970) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-16(13-18)15-9-11-17(12-10-15)29-14-21(23(25,26)27)28-22(29)19-7-2-3-8-20(19)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034781 (CHEMBL3360969) Show SMILES CC(C)(O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C23H21ClN2O3S2/c1-23(2,27)22-14-19(26(25-22)18-10-5-4-9-17(18)24)21-12-11-20(30-21)15-7-6-8-16(13-15)31(3,28)29/h4-14,27H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034782 (CHEMBL3360968) Show SMILES COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C22H17ClN2O4S2/c1-29-22(26)17-13-19(25(24-17)18-9-4-3-8-16(18)23)21-11-10-20(30-21)14-6-5-7-15(12-14)31(2,27)28/h3-13H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034783 (CHEMBL3360967) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-9-5-7-16(13-18)15-6-4-8-17(12-15)21-14-22(23(25,26)27)28-29(21)20-11-3-2-10-19(20)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034784 (CHEMBL3360966) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-17(13-18)15-9-11-16(12-10-15)21-14-22(23(25,26)27)28-29(21)20-8-3-2-7-19(20)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034785 (CHEMBL3360965) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H14F6N2O2S2/c1-34(31,32)14-6-4-5-13(11-14)18-9-10-19(33-18)17-12-20(22(26,27)28)29-30(17)16-8-3-2-7-15(16)21(23,24)25/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034786 (CHEMBL3360964) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C21H14ClF3N2O2S2/c1-31(28,29)14-6-4-5-13(11-14)18-9-10-19(30-18)17-12-20(21(23,24)25)26-27(17)16-8-3-2-7-15(16)22/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034788 (CHEMBL3360963) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C22H15F5N2O2S2/c1-33(30,31)16-4-2-3-13(9-16)19-7-8-20(32-19)18-11-21(22(25,26)27)28-29(18)12-14-5-6-15(23)10-17(14)24/h2-11H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034789 (CHEMBL3360962) Show SMILES Cc1cc(CC(O)=O)ccc1-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C27H17F5N2O3S/c1-14-8-15(9-25(35)36)2-5-18(14)23-6-7-24(38-23)22-11-20(27(30,31)32)19(12-33)26(37)34(22)13-16-3-4-17(28)10-21(16)29/h2-8,10-11H,9,13H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034790 (CHEMBL3360961) Show SMILES Fc1ccc(Cn2c(cc(c(C#N)c2=O)C(F)(F)F)-c2ccc(Oc3ccccc3)cc2)c(F)c1 Show InChI InChI=1S/C26H15F5N2O2/c27-18-9-6-17(23(28)12-18)15-33-24(13-22(26(29,30)31)21(14-32)25(33)34)16-7-10-20(11-8-16)35-19-4-2-1-3-5-19/h1-13H,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034791 (CHEMBL3360960) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C25H15F5N2O3S2/c1-37(34,35)17-4-2-3-14(9-17)22-7-8-23(36-22)21-11-19(25(28,29)30)18(12-31)24(33)32(21)13-15-5-6-16(26)10-20(15)27/h2-11H,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) Show SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034775 (CHEMBL3360975 | US10543183, Compound 38 | US109459...) Show SMILES CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034776 (CHEMBL3360974) Show SMILES CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C26H25ClN2O3S/c1-26(2,30)24-17-29(25(28-24)16-20-7-4-5-10-23(20)27)21-13-11-18(12-14-21)19-8-6-9-22(15-19)33(3,31)32/h4-15,17,30H,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034777 (CHEMBL3360973) Show SMILES CC(C)(O)c1cn(c(Cc2ccccc2C(F)(F)F)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C27H25F3N2O3S/c1-26(2,33)24-17-32(25(31-24)16-20-7-4-5-10-23(20)27(28,29)30)21-13-11-18(12-14-21)19-8-6-9-22(15-19)36(3,34)35/h4-15,17,33H,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034778 (CHEMBL3360972) Show SMILES CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O |(.07,-55.05,;1.6,-55.21,;2.22,-56.62,;.5,-56.3,;2.5,-53.97,;4.04,-53.97,;4.53,-52.5,;3.27,-51.6,;2.03,-52.51,;3.27,-50.06,;1.94,-49.3,;.61,-50.08,;1.93,-47.77,;3.27,-46.98,;4.61,-47.75,;4.61,-49.29,;6.09,-48.88,;5.84,-51.71,;7.18,-52.45,;8.5,-51.66,;8.47,-50.12,;7.12,-49.38,;5.8,-50.17,;9.79,-49.32,;11.14,-50.07,;12.45,-49.27,;12.42,-47.73,;11.06,-46.99,;9.75,-47.79,;11.02,-45.45,;12.34,-44.64,;9.53,-45.04,;10.62,-43.95,)| Show InChI InChI=1S/C25H22Cl2N2O3S/c1-25(2,30)22-15-29(24(28-22)23-20(26)8-5-9-21(23)27)18-12-10-16(11-13-18)17-6-4-7-19(14-17)33(3,31)32/h4-15,30H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034779 (CHEMBL3360971) Show SMILES CC(C)(O)c1cn(c(n1)-c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C25H23ClN2O3S/c1-25(2,29)23-16-28(24(27-23)21-9-4-5-10-22(21)26)19-13-11-17(12-14-19)18-7-6-8-20(15-18)32(3,30)31/h4-16,29H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034780 (CHEMBL3360970) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-16(13-18)15-9-11-17(12-10-15)29-14-21(23(25,26)27)28-22(29)19-7-2-3-8-20(19)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034781 (CHEMBL3360969) Show SMILES CC(C)(O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C23H21ClN2O3S2/c1-23(2,27)22-14-19(26(25-22)18-10-5-4-9-17(18)24)21-12-11-20(30-21)15-7-6-8-16(13-15)31(3,28)29/h4-14,27H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034782 (CHEMBL3360968) Show SMILES COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C22H17ClN2O4S2/c1-29-22(26)17-13-19(25(24-17)18-9-4-3-8-16(18)23)21-11-10-20(30-21)14-6-5-7-15(12-14)31(2,27)28/h3-13H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034783 (CHEMBL3360967) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-9-5-7-16(13-18)15-6-4-8-17(12-15)21-14-22(23(25,26)27)28-29(21)20-11-3-2-10-19(20)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034784 (CHEMBL3360966) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-17(13-18)15-9-11-16(12-10-15)21-14-22(23(25,26)27)28-29(21)20-8-3-2-7-19(20)24/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034785 (CHEMBL3360965) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H14F6N2O2S2/c1-34(31,32)14-6-4-5-13(11-14)18-9-10-19(33-18)17-12-20(22(26,27)28)29-30(17)16-8-3-2-7-15(16)21(23,24)25/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034786 (CHEMBL3360964) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C21H14ClF3N2O2S2/c1-31(28,29)14-6-4-5-13(11-14)18-9-10-19(30-18)17-12-20(21(23,24)25)26-27(17)16-8-3-2-7-15(16)22/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034788 (CHEMBL3360963) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C22H15F5N2O2S2/c1-33(30,31)16-4-2-3-13(9-16)19-7-8-20(32-19)18-11-21(22(25,26)27)28-29(18)12-14-5-6-15(23)10-17(14)24/h2-11H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034789 (CHEMBL3360962) Show SMILES Cc1cc(CC(O)=O)ccc1-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C27H17F5N2O3S/c1-14-8-15(9-25(35)36)2-5-18(14)23-6-7-24(38-23)22-11-20(27(30,31)32)19(12-33)26(37)34(22)13-16-3-4-17(28)10-21(16)29/h2-8,10-11H,9,13H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034790 (CHEMBL3360961) Show SMILES Fc1ccc(Cn2c(cc(c(C#N)c2=O)C(F)(F)F)-c2ccc(Oc3ccccc3)cc2)c(F)c1 Show InChI InChI=1S/C26H15F5N2O2/c27-18-9-6-17(23(28)12-18)15-33-24(13-22(26(29,30)31)21(14-32)25(33)34)16-7-10-20(11-8-16)35-19-4-2-1-3-5-19/h1-13H,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034791 (CHEMBL3360960) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F Show InChI InChI=1S/C25H15F5N2O3S2/c1-37(34,35)17-4-2-3-14(9-17)22-7-8-23(36-22)21-11-19(25(28,29)30)18(12-31)24(33)32(21)13-15-5-6-16(26)10-20(15)27/h2-11H,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM28530 (Azepino[4,5-b]indole, 6a | propan-2-yl 3-[(4-fluor...) Show SMILES CC(C)OC(=O)C1=CN(CCc2c1[nH]c1ccccc21)C(=O)c1ccc(F)cc1 |t:6| Show InChI InChI=1S/C23H21FN2O3/c1-14(2)29-23(28)19-13-26(22(27)15-7-9-16(24)10-8-15)12-11-18-17-5-3-4-6-20(17)25-21(18)19/h3-10,13-14,25H,11-12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	7.0	22
Exelixis Inc.					Assay Description The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...				J Med Chem 52: 904-7 (2009) Article DOI: 10.1021/jm8014124 BindingDB Entry DOI: 10.7270/Q2J38QVJ
					More data for this Ligand-Target Pair