Compile Data Set for Download or QSAR

Found 225 hits with Last Name = 'gradén' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296045 (CHEMBL562847 | N-(1-(6-oxo-1,6-dihydropyridin-3-yl...) Show SMILES CCCCC(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(=O)[nH]c1 Show InChI InChI=1S/C29H35F3N4O2/c1-2-3-4-26(23-5-10-27(37)33-18-23)34-28(38)17-21-11-14-35(15-12-21)19-22-13-16-36(20-22)25-8-6-24(7-9-25)29(30,31)32/h5-10,13,16,18,20-21,26H,2-4,11-12,14-15,17,19H2,1H3,(H,33,37)(H,34,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296041 (CHEMBL553196 | N-((4-fluorophenyl)(6-methoxypyridi...) Show SMILES COc1ccc(cn1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C32H32F4N4O2/c1-42-30-11-4-25(19-37-30)31(24-2-7-27(33)8-3-24)38-29(41)18-22-12-15-39(16-13-22)20-23-14-17-40(21-23)28-9-5-26(6-10-28)32(34,35)36/h2-11,14,17,19,21-22,31H,12-13,15-16,18,20H2,1H3,(H,38,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296044 (CHEMBL554332 | N-((4-fluorophenyl)(6-oxo-1,6-dihyd...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(=O)[nH]c1 Show InChI InChI=1S/C31H30F4N4O2/c32-26-6-1-23(2-7-26)30(24-3-10-28(40)36-18-24)37-29(41)17-21-11-14-38(15-12-21)19-22-13-16-39(20-22)27-8-4-25(5-9-27)31(33,34)35/h1-10,13,16,18,20-21,30H,11-12,14-15,17,19H2,(H,36,40)(H,37,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296019 (CHEMBL549635 | N-(4-fluorobenzyl)-N-(3-hydroxyprop...) Show SMILES OCCCN(Cc1ccc(F)cc1)C(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C29H33F4N3O2/c30-26-6-2-23(3-7-26)20-36(13-1-17-37)28(38)18-22-10-14-34(15-11-22)19-24-12-16-35(21-24)27-8-4-25(5-9-27)29(31,32)33/h2-9,12,16,21-22,37H,1,10-11,13-15,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296042 (CHEMBL549984 | N-(1-(6-methoxypyridin-3-yl)pentyl)...) Show SMILES CCCCC(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(OC)nc1 Show InChI InChI=1S/C30H37F3N4O2/c1-3-4-5-27(24-6-11-29(39-2)34-19-24)35-28(38)18-22-12-15-36(16-13-22)20-23-14-17-37(21-23)26-9-7-25(8-10-26)30(31,32)33/h6-11,14,17,19,21-22,27H,3-5,12-13,15-16,18,20H2,1-2H3,(H,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296043 (CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1c[nH]c(=O)c(Cl)c1 Show InChI InChI=1S/C31H29ClF4N4O2/c32-27-16-23(17-37-30(27)42)29(22-1-5-25(33)6-2-22)38-28(41)15-20-9-12-39(13-10-20)18-21-11-14-40(19-21)26-7-3-24(4-8-26)31(34,35)36/h1-8,11,14,16-17,19-20,29H,9-10,12-13,15,18H2,(H,37,42)(H,38,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296047 (CHEMBL554511 | N-(2,4-dichlorobenzyl)-4-((1-(4-(tr...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C24H23Cl2F3N4O/c25-20-4-1-18(22(26)13-20)14-30-23(34)32-11-9-31(10-12-32)15-17-7-8-33(16-17)21-5-2-19(3-6-21)24(27,28)29/h1-8,13,16H,9-12,14-15H2,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297624 (1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCn3cccc3C2c2ccccc2)c1 Show InChI InChI=1S/C31H32F3N5O/c32-31(33,34)25-8-10-27(11-9-25)38-18-12-23(22-38)21-36-16-13-26(14-17-36)35-30(40)39-20-19-37-15-4-7-28(37)29(39)24-5-2-1-3-6-24/h1-12,15,18,22,26,29H,13-14,16-17,19-21H2,(H,35,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297625 (1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethyl)...) Show SMILES Cc1cc(C)n(CC(NC(=O)NC2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)CC2)c2ccccc2)n1 Show InChI InChI=1S/C31H35F3N6O/c1-22-18-23(2)40(37-22)21-29(25-6-4-3-5-7-25)36-30(41)35-27-13-15-38(16-14-27)19-24-12-17-39(20-24)28-10-8-26(9-11-28)31(32,33)34/h3-12,17-18,20,27,29H,13-16,19,21H2,1-2H3,(H2,35,36,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297626 (2-(4-fluorophenyl)-N-(1-((1-(4-(trifluoromethyl)ph...) Show SMILES Fc1ccc(cc1)C1CCCN1C(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C28H30F4N4O/c29-23-7-3-21(4-8-23)26-2-1-14-36(26)27(37)33-24-12-15-34(16-13-24)18-20-11-17-35(19-20)25-9-5-22(6-10-25)28(30,31)32/h3-11,17,19,24,26H,1-2,12-16,18H2,(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296017 (CHEMBL538936 | N-(bis(4-fluorophenyl)methyl)-2-(1-...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cn2)C(F)(F)F)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C31H29F5N4O/c32-26-6-1-23(2-7-26)30(24-3-8-27(33)9-4-24)38-29(41)17-21-11-14-39(15-12-21)19-22-13-16-40(20-22)28-10-5-25(18-37-28)31(34,35)36/h1-10,13,16,18,20-21,30H,11-12,14-15,17,19H2,(H,38,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245487 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O3/c26-19-2-1-3-23(14-19)34-17-24(33)30-20-9-11-31(12-10-20)15-18-8-13-32(16-18)21-4-6-22(7-5-21)35-25(27,28)29/h1-8,13-14,16,20H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296017 (CHEMBL538936 | N-(bis(4-fluorophenyl)methyl)-2-(1-...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cn2)C(F)(F)F)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C31H29F5N4O/c32-26-6-1-23(2-7-26)30(24-3-8-27(33)9-4-24)38-29(41)17-21-11-14-39(15-12-21)19-22-13-16-40(20-22)28-10-5-25(18-37-28)31(34,35)36/h1-10,13,16,18,20-21,30H,11-12,14-15,17,19H2,(H,38,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296035 (CHEMBL559535 | N-((1H-imidazol-5-yl)(phenyl)methyl...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC(=O)NC(c3cnc[nH]3)c3ccccc3)CC2)c1 Show InChI InChI=1S/C29H30F3N5O/c30-29(31,32)24-6-8-25(9-7-24)37-15-12-22(19-37)18-36-13-10-21(11-14-36)16-27(38)35-28(26-17-33-20-34-26)23-4-2-1-3-5-23/h1-9,12,15,17,19-21,28H,10-11,13-14,16,18H2,(H,33,34)(H,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297627 (1-(1-phenyl-2-(pyrazin-2-yl)ethyl)-3-(1-((1-(4-(tr...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(Cc2cnccn2)c2ccccc2)c1 Show InChI InChI=1S/C30H31F3N6O/c31-30(32,33)24-6-8-27(9-7-24)39-17-10-22(21-39)20-38-15-11-25(12-16-38)36-29(40)37-28(23-4-2-1-3-5-23)18-26-19-34-13-14-35-26/h1-10,13-14,17,19,21,25,28H,11-12,15-16,18,20H2,(H2,36,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296038 (CHEMBL551924 | N-((4-chlorophenyl)(pyridin-4-yl)me...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC(=O)NC(c3ccncc3)c3ccc(Cl)cc3)CC2)c1 Show InChI InChI=1S/C31H30ClF3N4O/c32-27-5-1-24(2-6-27)30(25-9-14-36-15-10-25)37-29(40)19-22-11-16-38(17-12-22)20-23-13-18-39(21-23)28-7-3-26(4-8-28)31(33,34)35/h1-10,13-15,18,21-22,30H,11-12,16-17,19-20H2,(H,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297628 (1-(1-phenyl-2-(1H-pyrazol-1-yl)ethyl)-3-(1-((1-(4-...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(Cn2cccn2)c2ccccc2)c1 Show InChI InChI=1S/C29H31F3N6O/c30-29(31,32)24-7-9-26(10-8-24)37-18-11-22(20-37)19-36-16-12-25(13-17-36)34-28(39)35-27(21-38-15-4-14-33-38)23-5-2-1-3-6-23/h1-11,14-15,18,20,25,27H,12-13,16-17,19,21H2,(H2,34,35,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296045 (CHEMBL562847 | N-(1-(6-oxo-1,6-dihydropyridin-3-yl...) Show SMILES CCCCC(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(=O)[nH]c1 Show InChI InChI=1S/C29H35F3N4O2/c1-2-3-4-26(23-5-10-27(37)33-18-23)34-28(38)17-21-11-14-35(15-12-21)19-22-13-16-36(20-22)25-8-6-24(7-9-25)29(30,31)32/h5-10,13,16,18,20-21,26H,2-4,11-12,14-15,17,19H2,1H3,(H,33,37)(H,34,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245681 (4-(5-(4-fluorophenyl)-1H-imidazol-2-yl)-1-((1-(4-(...) Show SMILES Fc1ccc(cc1)-c1c[nH]c(n1)C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C26H24F4N4/c27-22-5-1-19(2-6-22)24-15-31-25(32-24)20-10-12-33(13-11-20)16-18-9-14-34(17-18)23-7-3-21(4-8-23)26(28,29)30/h1-9,14-15,17,20H,10-13,16H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296043 (CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1c[nH]c(=O)c(Cl)c1 Show InChI InChI=1S/C31H29ClF4N4O2/c32-27-16-23(17-37-30(27)42)29(22-1-5-25(33)6-2-22)38-28(41)15-20-9-12-39(13-10-20)18-21-11-14-40(19-21)26-7-3-24(4-8-26)31(34,35)36/h1-8,11,14,16-17,19-20,29H,9-10,12-13,15,18H2,(H,37,42)(H,38,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296040 (3-((4-fluorophenyl)(2-(1-((1-(4-(trifluoromethyl)p...) Show SMILES [O-][n+]1cccc(c1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C31H30F4N4O2/c32-27-7-3-24(4-8-27)30(25-2-1-14-39(41)21-25)36-29(40)18-22-11-15-37(16-12-22)19-23-13-17-38(20-23)28-9-5-26(6-10-28)31(33,34)35/h1-10,13-14,17,20-22,30H,11-12,15-16,18-19H2,(H,36,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297629 (2-(pyridin-3-yl)-N-(1-((1-(4-(trifluoromethyl)phen...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCCC2c2cccnc2)c1 Show InChI InChI=1S/C27H30F3N5O/c28-27(29,30)22-5-7-24(8-6-22)34-16-9-20(19-34)18-33-14-10-23(11-15-33)32-26(36)35-13-2-4-25(35)21-3-1-12-31-17-21/h1,3,5-9,12,16-17,19,23,25H,2,4,10-11,13-15,18H2,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296025 (CHEMBL558442 | N-(4-chloro-2-hydroxybenzyl)-1-((1-...) Show SMILES Oc1cc(Cl)ccc1CNC(=O)C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-21-4-1-19(23(33)13-21)14-30-24(34)18-8-10-31(11-9-18)15-17-7-12-32(16-17)22-5-2-20(3-6-22)25(27,28)29/h1-7,12-13,16,18,33H,8-11,14-15H2,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297630 (3-(hydroxymethyl)-N-(1-((1-(4-(trifluoromethyl)phe...) Show SMILES OCC1CCCN(C1)C(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C24H31F3N4O2/c25-24(26,27)20-3-5-22(6-4-20)30-13-7-18(15-30)14-29-11-8-21(9-12-29)28-23(33)31-10-1-2-19(16-31)17-32/h3-7,13,15,19,21,32H,1-2,8-12,14,16-17H2,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296044 (CHEMBL554332 | N-((4-fluorophenyl)(6-oxo-1,6-dihyd...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(=O)[nH]c1 Show InChI InChI=1S/C31H30F4N4O2/c32-26-6-1-23(2-7-26)30(24-3-10-28(40)36-18-24)37-29(41)17-21-11-14-38(15-12-21)19-22-13-16-39(20-22)27-8-4-25(5-9-27)31(33,34)35/h1-10,13,16,18,20-21,30H,11-12,14-15,17,19H2,(H,36,40)(H,37,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245725 (4-(5-(4-fluorophenyl)isoxazol-3-yl)-1-((1-(4-(trif...) Show SMILES Fc1ccc(cc1)-c1cc(no1)C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C26H23F4N3O/c27-22-5-1-20(2-6-22)25-15-24(31-34-25)19-10-12-32(13-11-19)16-18-9-14-33(17-18)23-7-3-21(4-8-23)26(28,29)30/h1-9,14-15,17,19H,10-13,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297621 (1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(Cn2ccnc2)c2ccccc2)c1 Show InChI InChI=1S/C29H31F3N6O/c30-29(31,32)24-6-8-26(9-7-24)38-16-10-22(19-38)18-36-14-11-25(12-15-36)34-28(39)35-27(20-37-17-13-33-21-37)23-4-2-1-3-5-23/h1-10,13,16-17,19,21,25,27H,11-12,14-15,18,20H2,(H2,34,35,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245768 (5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phe...) Show SMILES Cc1c([nH]c(=O)n1C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)-c1ccccc1 Show InChI InChI=1S/C27H27F3N4O/c1-19-25(21-5-3-2-4-6-21)31-26(35)34(19)24-12-14-32(15-13-24)17-20-11-16-33(18-20)23-9-7-22(8-10-23)27(28,29)30/h2-11,16,18,24H,12-15,17H2,1H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297631 (2-(pyridin-3-ylmethyl)-N-(1-((1-(4-(trifluoromethy...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCCC2Cc2cccnc2)c1 Show InChI InChI=1S/C28H32F3N5O/c29-28(30,31)23-5-7-25(8-6-23)35-16-9-22(20-35)19-34-14-10-24(11-15-34)33-27(37)36-13-2-4-26(36)17-21-3-1-12-32-18-21/h1,3,5-9,12,16,18,20,24,26H,2,4,10-11,13-15,17,19H2,(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297632 (1-((1H-imidazol-2-yl)(phenyl)methyl)-3-(1-((1-(4-(...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(c2ncc[nH]2)c2ccccc2)c1 Show InChI InChI=1S/C28H29F3N6O/c29-28(30,31)22-6-8-24(9-7-22)37-17-10-20(19-37)18-36-15-11-23(12-16-36)34-27(38)35-25(26-32-13-14-33-26)21-4-2-1-3-5-21/h1-10,13-14,17,19,23,25H,11-12,15-16,18H2,(H,32,33)(H2,34,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297633 (4-methyl-2-phenyl-N-(1-((1-(4-(trifluoromethyl)phe...) Show SMILES CN1CCN(C(C1)c1ccccc1)C(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C29H34F3N5O/c1-34-17-18-37(27(21-34)23-5-3-2-4-6-23)28(38)33-25-12-14-35(15-13-25)19-22-11-16-36(20-22)26-9-7-24(8-10-26)29(30,31)32/h2-11,16,20,25,27H,12-15,17-19,21H2,1H3,(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296039 (CHEMBL565073 | N-((4-fluorophenyl)(pyridin-3-yl)me...) Show SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1cccnc1 Show InChI InChI=1S/C31H30F4N4O/c32-27-7-3-24(4-8-27)30(25-2-1-14-36-19-25)37-29(40)18-22-11-15-38(16-12-22)20-23-13-17-39(21-23)28-9-5-26(6-10-28)31(33,34)35/h1-10,13-14,17,19,21-22,30H,11-12,15-16,18,20H2,(H,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245568 (2-(3,4-difluorophenoxy)-N-(1-((1-(4-(trifluorometh...) Show SMILES Fc1ccc(OCC(=O)NC2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)C2)cc1F Show InChI InChI=1S/C24H22F5N3O2/c25-21-6-5-20(11-22(21)26)34-15-23(33)30-18-8-9-31(14-18)12-16-7-10-32(13-16)19-3-1-17(2-4-19)24(27,28)29/h1-7,10-11,13,18H,8-9,12,14-15H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245454 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-20-2-1-3-23(14-20)34-17-24(33)30-21-9-11-31(12-10-21)15-18-8-13-32(16-18)22-6-4-19(5-7-22)25(27,28)29/h1-8,13-14,16,21H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245454 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-20-2-1-3-23(14-20)34-17-24(33)30-21-9-11-31(12-10-21)15-18-8-13-32(16-18)22-6-4-19(5-7-22)25(27,28)29/h1-8,13-14,16,21H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245454 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-20-2-1-3-23(14-20)34-17-24(33)30-21-9-11-31(12-10-21)15-18-8-13-32(16-18)22-6-4-19(5-7-22)25(27,28)29/h1-8,13-14,16,21H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296024 (CHEMBL550308 | N-(2-chloro-4-hydroxybenzyl)-1-((1-...) Show SMILES Oc1ccc(CNC(=O)C2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)CC2)c(Cl)c1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-23-13-22(33)6-1-19(23)14-30-24(34)18-8-10-31(11-9-18)15-17-7-12-32(16-17)21-4-2-20(3-5-21)25(27,28)29/h1-7,12-13,16,18,33H,8-11,14-15H2,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245487 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O3/c26-19-2-1-3-23(14-19)34-17-24(33)30-20-9-11-31(12-10-20)15-18-8-13-32(16-18)21-4-6-22(7-5-21)35-25(27,28)29/h1-8,13-14,16,20H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245454 (2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1 Show InChI InChI=1S/C25H25ClF3N3O2/c26-20-2-1-3-23(14-20)34-17-24(33)30-21-9-11-31(12-10-21)15-18-8-13-32(16-18)22-6-4-19(5-7-22)25(27,28)29/h1-8,13-14,16,21H,9-12,15,17H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulation				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297634 ((S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...) Show SMILES OC[C@@H](NC(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccccc1 |r| Show InChI InChI=1S/C26H29F3N4O2/c27-26(28,29)21-6-8-23(9-7-21)33-15-10-19(17-33)16-32-13-11-22(12-14-32)30-25(35)31-24(18-34)20-4-2-1-3-5-20/h1-10,15,17,22,24,34H,11-14,16,18H2,(H2,30,31,35)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297635 (4-(2-hydroxyphenyl)-N-(1-((1-(4-(trifluoromethyl)p...) Show SMILES Oc1ccccc1C1CCN(CC1)C(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C29H33F3N4O2/c30-29(31,32)23-5-7-25(8-6-23)36-16-9-21(20-36)19-34-14-12-24(13-15-34)33-28(38)35-17-10-22(11-18-35)26-3-1-2-4-27(26)37/h1-9,16,20,22,24,37H,10-15,17-19H2,(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50245724 (4-(5-(4-fluorophenyl)-1H-pyrazol-3-yl)-1-((1-(4-(t...) Show SMILES Fc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C26H24F4N4/c27-22-5-1-19(2-6-22)24-15-25(32-31-24)20-10-12-33(13-11-20)16-18-9-14-34(17-18)23-7-3-21(4-8-23)26(28,29)30/h1-9,14-15,17,20H,10-13,16H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4859-63 (2008) Article DOI: 10.1016/j.bmcl.2008.07.079 BindingDB Entry DOI: 10.7270/Q2125SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296030 (CHEMBL561463 | N,N-diethyl-1-(2-(1-((1-(4-(trifluo...) Show SMILES CCN(CC)C(=O)C1CCCN(C1)C(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C29H39F3N4O2/c1-3-34(4-2)28(38)24-6-5-14-36(21-24)27(37)18-22-11-15-33(16-12-22)19-23-13-17-35(20-23)26-9-7-25(8-10-26)29(30,31)32/h7-10,13,17,20,22,24H,3-6,11-12,14-16,18-19,21H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297620 (1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(Cn2cncn2)c2ccccc2)c1 Show InChI InChI=1S/C28H30F3N7O/c29-28(30,31)23-6-8-25(9-7-23)37-15-10-21(17-37)16-36-13-11-24(12-14-36)34-27(39)35-26(18-38-20-32-19-33-38)22-4-2-1-3-5-22/h1-10,15,17,19-20,24,26H,11-14,16,18H2,(H2,34,35,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296048 (1-benzhydryl-3-(1-((1-(4-(trifluoromethyl)phenyl)-...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C31H31F3N4O/c32-31(33,34)26-11-13-28(14-12-26)38-20-15-23(22-38)21-37-18-16-27(17-19-37)35-30(39)36-29(24-7-3-1-4-8-24)25-9-5-2-6-10-25/h1-15,20,22,27,29H,16-19,21H2,(H2,35,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297636 (1-(3-fluorobenzyl)-3-(1-((1-(4-(trifluoromethyl)ph...) Show SMILES Fc1cccc(CNC(=O)NC2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)CC2)c1 Show InChI InChI=1S/C25H26F4N4O/c26-21-3-1-2-18(14-21)15-30-24(34)31-22-9-11-32(12-10-22)16-19-8-13-33(17-19)23-6-4-20(5-7-23)25(27,28)29/h1-8,13-14,17,22H,9-12,15-16H2,(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297637 (2-(2-hydroxyethyl)-N-(1-((1-(4-(trifluoromethyl)ph...) Show SMILES OCCC1CCCCN1C(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C25H33F3N4O2/c26-25(27,28)20-4-6-22(7-5-20)31-15-8-19(18-31)17-30-13-9-21(10-14-30)29-24(34)32-12-2-1-3-23(32)11-16-33/h4-8,15,18,21,23,33H,1-3,9-14,16-17H2,(H,29,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297638 (3-(pyrrolidine-1-carbonyl)-N-(1-((1-(4-(trifluorom...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCCC(C2)C(=O)N2CCCC2)c1 Show InChI InChI=1S/C28H36F3N5O2/c29-28(30,31)23-5-7-25(8-6-23)35-17-9-21(19-35)18-33-15-10-24(11-16-33)32-27(38)36-14-3-4-22(20-36)26(37)34-12-1-2-13-34/h5-9,17,19,22,24H,1-4,10-16,18,20H2,(H,32,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50296023 (CHEMBL557715 | N-((1-hydroxycyclohexyl)methyl)-1-(...) Show SMILES OC1(CNC(=O)C2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)CC2)CCCCC1 Show InChI InChI=1S/C25H32F3N3O2/c26-25(27,28)21-4-6-22(7-5-21)31-15-8-19(17-31)16-30-13-9-20(10-14-30)23(32)29-18-24(33)11-2-1-3-12-24/h4-8,15,17,20,33H,1-3,9-14,16,18H2,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4268-73 (2009) Article DOI: 10.1016/j.bmcl.2009.05.067 BindingDB Entry DOI: 10.7270/Q2RX9C4H
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50297621 (1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)NC(Cn2ccnc2)c2ccccc2)c1 Show InChI InChI=1S/C29H31F3N6O/c30-29(31,32)24-6-8-26(9-7-24)38-16-10-22(19-38)18-36-14-11-25(12-15-36)34-28(39)35-27(20-37-17-13-33-21-37)23-4-2-1-3-5-23/h1-10,13,16-17,19,21,25,27H,11-12,14-15,18,20H2,(H2,34,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 after 45 mins				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair

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