Compile Data Set for Download or QSAR

Found 83 hits with Last Name = 'graham' and Initial = 'me'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50177941 (2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C22H18N4O8/c23-9-13(3-11-5-15(27)19(31)16(28)6-11)21(33)25-1-2-26-22(34)14(10-24)4-12-7-17(29)20(32)18(30)8-12/h3-8,27-32H,1-2H2,(H,25,33)(H,26,34)/b13-3+,14-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5149 ((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C23H20N4O6/c24-12-16(8-14-2-4-18(28)20(30)10-14)22(32)26-6-1-7-27-23(33)17(13-25)9-15-3-5-19(29)21(31)11-15/h2-5,8-11,28-31H,1,6-7H2,(H,26,32)(H,27,33)/b16-8+,17-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177923 (2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C25H24N4O8/c26-12-16(6-14-8-18(30)22(34)19(31)9-14)24(36)28-4-2-1-3-5-29-25(37)17(13-27)7-15-10-20(32)23(35)21(33)11-15/h6-11,30-35H,1-5H2,(H,28,36)(H,29,37)/b16-6+,17-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177937 (2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C23H20N4O8/c24-10-14(4-12-6-16(28)20(32)17(29)7-12)22(34)26-2-1-3-27-23(35)15(11-25)5-13-8-18(30)21(33)19(31)9-13/h4-9,28-33H,1-3H2,(H,26,34)(H,27,35)/b14-4+,15-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5152 ((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C24H22N4O8/c25-11-15(5-13-7-17(29)21(33)18(30)8-13)23(35)27-3-1-2-4-28-24(36)16(12-26)6-14-9-19(31)22(34)20(32)10-14/h5-10,29-34H,1-4H2,(H,27,35)(H,28,36)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5151 ((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C24H22N4O6/c25-13-17(9-15-3-5-19(29)21(31)11-15)23(33)27-7-1-2-8-28-24(34)18(14-26)10-16-4-6-20(30)22(32)12-16/h3-6,9-12,29-32H,1-2,7-8H2,(H,27,33)(H,28,34)/b17-9+,18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5153 ((2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C25H24N4O6/c26-14-18(10-16-4-6-20(30)22(32)12-16)24(34)28-8-2-1-3-9-29-25(35)19(15-27)11-17-5-7-21(31)23(33)13-17/h4-7,10-13,30-33H,1-3,8-9H2,(H,28,34)(H,29,35)/b18-10+,19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177943 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C25H24N4O8/c1-36-20-10-14(8-18(30)22(20)32)6-16(12-26)24(34)28-4-3-5-29-25(35)17(13-27)7-15-9-19(31)23(33)21(11-15)37-2/h6-11,30-33H,3-5H2,1-2H3,(H,28,34)(H,29,35)/b16-6+,17-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177940 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxyphenyl)acryl...) Show SMILES OC(CNC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)CNC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C23H20N4O7/c24-9-15(5-13-1-3-18(29)20(31)7-13)22(33)26-11-17(28)12-27-23(34)16(10-25)6-14-2-4-19(30)21(32)8-14/h1-8,17,28-32H,11-12H2,(H,26,33)(H,27,34)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5150 ((2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C22H18N4O6/c23-11-15(7-13-1-3-17(27)19(29)9-13)21(31)25-5-6-26-22(32)16(12-24)8-14-2-4-18(28)20(30)10-14/h1-4,7-10,27-30H,5-6H2,(H,25,31)(H,26,32)/b15-7+,16-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177965 (2-cyano-N-{3-[-2-cyano-3-(3,4,5-trihydroxyphenyl)a...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C26H26N4O8/c27-13-17(7-15-9-19(31)23(35)20(32)10-15)25(37)29-5-3-1-2-4-6-30-26(38)18(14-28)8-16-11-21(33)24(36)22(34)12-16/h7-12,31-36H,1-6H2,(H,29,37)(H,30,38)/b17-7+,18-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177973 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C26H26N4O8/c1-37-21-11-15(9-19(31)23(21)33)7-17(13-27)25(35)29-5-3-4-6-30-26(36)18(14-28)8-16-10-20(32)24(34)22(12-16)38-2/h7-12,31-34H,3-6H2,1-2H3,(H,29,35)(H,30,36)/b17-7+,18-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177944 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C27H28N4O8/c1-38-22-12-16(10-20(32)24(22)34)8-18(14-28)26(36)30-6-4-3-5-7-31-27(37)19(15-29)9-17-11-21(33)25(35)23(13-17)39-2/h8-13,32-35H,3-7H2,1-2H3,(H,30,36)(H,31,37)/b18-8+,19-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177955 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C24H22N4O8/c1-35-19-9-13(7-17(29)21(19)31)5-15(11-25)23(33)27-3-4-28-24(34)16(12-26)6-14-8-18(30)22(32)20(10-14)36-2/h5-10,29-32H,3-4H2,1-2H3,(H,27,33)(H,28,34)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5154 ((2E)-2-cyano-N-{6-[(2E)-2-cyano-3-(3,4-dihydroxyph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C26H26N4O6/c27-15-19(11-17-5-7-21(31)23(33)13-17)25(35)29-9-3-1-2-4-10-30-26(36)20(16-28)12-18-6-8-22(32)24(34)14-18/h5-8,11-14,31-34H,1-4,9-10H2,(H,29,35)(H,30,36)/b19-11+,20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177950 (2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-c...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCOC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C23H18N2O8/c24-12-16(8-14-2-4-18(26)20(28)10-14)22(30)32-6-1-7-33-23(31)17(13-25)9-15-3-5-19(27)21(29)11-15/h2-5,8-11,26-29H,1,6-7H2/b16-8+,17-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177970 (2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-c...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCOC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C22H16N2O8/c23-11-15(7-13-1-3-17(25)19(27)9-13)21(29)31-5-6-32-22(30)16(12-24)8-14-2-4-18(26)20(28)10-14/h1-4,7-10,25-28H,5-6H2/b15-7+,16-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177915 (2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid 2-[2-c...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCOC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C24H20N2O8/c25-13-17(9-15-3-5-19(27)21(29)11-15)23(31)33-7-1-2-8-34-24(32)18(14-26)10-16-4-6-20(28)22(30)12-16/h3-6,9-12,27-30H,1-2,7-8H2/b17-9+,18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM4363 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...) Show SMILES NC(=S)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177930 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C28H30N4O8/c1-39-23-13-17(11-21(33)25(23)35)9-19(15-29)27(37)31-7-5-3-4-6-8-32-28(38)20(16-30)10-18-12-22(34)26(36)24(14-18)40-2/h9-14,33-36H,3-8H2,1-2H3,(H,31,37)(H,32,38)/b19-9+,20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM5156 ((2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxy...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCc2cccc(CNC(=O)C(=C\c3ccc(O)c(O)c3)\C#N)c2)cc1O Show InChI InChI=1S/C28H22N4O6/c29-13-21(9-17-4-6-23(33)25(35)11-17)27(37)31-15-19-2-1-3-20(8-19)16-32-28(38)22(14-30)10-18-5-7-24(34)26(36)12-18/h1-12,33-36H,15-16H2,(H,31,37)(H,32,38)/b21-9+,22-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177951 (2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxyphenyl)acryl...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)N[C@H]2CCCC[C@@H]2NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C26H24N4O6/c27-13-17(9-15-5-7-21(31)23(33)11-15)25(35)29-19-3-1-2-4-20(19)30-26(36)18(14-28)10-16-6-8-22(32)24(34)12-16/h5-12,19-20,31-34H,1-4H2,(H,29,35)(H,30,36)/b17-9+,18-10+/t19-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177936 (2-cyano-N-{2-[2-cyano-3-(4-carboxyphenyl)acryloyla...) Show SMILES OC(=O)c1ccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2ccc(cc2)C(O)=O)\C#N)cc1 Show InChI InChI=1S/C24H18N4O6/c25-13-19(11-15-1-5-17(6-2-15)23(31)32)21(29)27-9-10-28-22(30)20(14-26)12-16-3-7-18(8-4-16)24(33)34/h1-8,11-12H,9-10H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/b19-11+,20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177932 (2-cyano-N-{14-[2-cyano-3-(3,4-dihydroxy-5-methoxyp...) Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCCCCCCCCNC(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C34H42N4O8/c1-45-29-19-23(17-27(39)31(29)41)15-25(21-35)33(43)37-13-11-9-7-5-3-4-6-8-10-12-14-38-34(44)26(22-36)16-24-18-28(40)32(42)30(20-24)46-2/h15-20,39-42H,3-14H2,1-2H3,(H,37,43)(H,38,44)/b25-15+,26-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177933 (2-cyano-N-{5-[2-cyano-3-(3-hydroxyphenyl)acryloyla...) Show SMILES Oc1cccc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cccc(O)c2)\C#N)c1 Show InChI InChI=1S/C25H24N4O4/c26-16-20(12-18-6-4-8-22(30)14-18)24(32)28-10-2-1-3-11-29-25(33)21(17-27)13-19-7-5-9-23(31)15-19/h4-9,12-15,30-31H,1-3,10-11H2,(H,28,32)(H,29,33)/b20-12+,21-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177934 (2-cyano-N-{3-[2-cyano-3-(3-methoxyphenyl)acryloyla...) Show SMILES COc1cccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cccc(OC)c2)\C#N)c1 Show InChI InChI=1S/C25H24N4O4/c1-32-22-8-3-6-18(14-22)12-20(16-26)24(30)28-10-5-11-29-25(31)21(17-27)13-19-7-4-9-23(15-19)33-2/h3-4,6-9,12-15H,5,10-11H2,1-2H3,(H,28,30)(H,29,31)/b20-12+,21-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177938 (2-cyano-N-{4-[2-cyano-3-(3-hydroxy-4-methoxyphenyl...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2ccc(OC)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C26H26N4O6/c1-35-23-7-5-17(13-21(23)31)11-19(15-27)25(33)29-9-3-4-10-30-26(34)20(16-28)12-18-6-8-24(36-2)22(32)14-18/h5-8,11-14,31-32H,3-4,9-10H2,1-2H3,(H,29,33)(H,30,34)/b19-11+,20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177942 (2-cyano-N-{2-[2-cyano-3-(3-methoxyphenyl)acryloyla...) Show SMILES COc1cccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cccc(OC)c2)\C#N)c1 Show InChI InChI=1S/C24H22N4O4/c1-31-21-7-3-5-17(13-21)11-19(15-25)23(29)27-9-10-28-24(30)20(16-26)12-18-6-4-8-22(14-18)32-2/h3-8,11-14H,9-10H2,1-2H3,(H,27,29)(H,28,30)/b19-11+,20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177945 (2-cyano-N-{3-[2-cyano-3-(4-hydroxyphenyl)acryloyla...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(O)cc2)\C#N)cc1 Show InChI InChI=1S/C23H20N4O4/c24-14-18(12-16-2-6-20(28)7-3-16)22(30)26-10-1-11-27-23(31)19(15-25)13-17-4-8-21(29)9-5-17/h2-9,12-13,28-29H,1,10-11H2,(H,26,30)(H,27,31)/b18-12+,19-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177939 (2-cyano-N-{3-[2-cyano-3-(3-hydroxyphenyl)acryloyla...) Show SMILES Oc1cccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cccc(O)c2)\C#N)c1 Show InChI InChI=1S/C23H20N4O4/c24-14-18(10-16-4-1-6-20(28)12-16)22(30)26-8-3-9-27-23(31)19(15-25)11-17-5-2-7-21(29)13-17/h1-2,4-7,10-13,28-29H,3,8-9H2,(H,26,30)(H,27,31)/b18-10+,19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177947 (2-cyano-N-(3-{[2-cyano-3-(3,4-dihydroxyphenyl)acry...) Show SMILES CN(CCCN(C)C(=O)C(=C\c1ccc(O)c(O)c1)\C#N)C(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C25H24N4O6/c1-28(24(34)18(14-26)10-16-4-6-20(30)22(32)12-16)8-3-9-29(2)25(35)19(15-27)11-17-5-7-21(31)23(33)13-17/h4-7,10-13,30-33H,3,8-9H2,1-2H3/b18-10+,19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177948 (2-cyano-N-[6-(2-cyano-3-phenylacryloylamino)hexyl]...) Show SMILES O=C(NCCCCCCNC(=O)C(=C\c1ccccc1)\C#N)C(=C\c1ccccc1)\C#N Show InChI InChI=1S/C26H26N4O2/c27-19-23(17-21-11-5-3-6-12-21)25(31)29-15-9-1-2-10-16-30-26(32)24(20-28)18-22-13-7-4-8-14-22/h3-8,11-14,17-18H,1-2,9-10,15-16H2,(H,29,31)(H,30,32)/b23-17+,24-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177949 (3-(4-chlorophenyl)-N-{5-[3-(4-chlorophenyl)-2-cyan...) Show SMILES Clc1cccc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cccc(Cl)c2)\C#N)c1 Show InChI InChI=1S/C25H22Cl2N4O2/c26-22-8-4-6-18(14-22)12-20(16-28)24(32)30-10-2-1-3-11-31-25(33)21(17-29)13-19-7-5-9-23(27)15-19/h4-9,12-15H,1-3,10-11H2,(H,30,32)(H,31,33)/b20-12+,21-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177946 (2-cyano-N-[2-(2-cyano-3-phenylacryloylamino)ethyl]...) Show SMILES O=C(NCCNC(=O)C(=C\c1ccccc1)\C#N)C(=C\c1ccccc1)\C#N Show InChI InChI=1S/C22H18N4O2/c23-15-19(13-17-7-3-1-4-8-17)21(27)25-11-12-26-22(28)20(16-24)14-18-9-5-2-6-10-18/h1-10,13-14H,11-12H2,(H,25,27)(H,26,28)/b19-13+,20-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177952 (3-(4-chlorophenyl)-N-{3-[3-(4-chlorophenyl)-2-cyan...) Show SMILES Clc1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(Cl)cc2)\C#N)cc1 Show InChI InChI=1S/C23H18Cl2N4O2/c24-20-6-2-16(3-7-20)12-18(14-26)22(30)28-10-1-11-29-23(31)19(15-27)13-17-4-8-21(25)9-5-17/h2-9,12-13H,1,10-11H2,(H,28,30)(H,29,31)/b18-12+,19-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177953 (2-cyano-N-{2-[2-cyano-3-(3,4-dimethoxyphenyl)acryl...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2ccc(OC)c(OC)c2)\C#N)cc1OC Show InChI InChI=1S/C26H26N4O6/c1-33-21-7-5-17(13-23(21)35-3)11-19(15-27)25(31)29-9-10-30-26(32)20(16-28)12-18-6-8-22(34-2)24(14-18)36-4/h5-8,11-14H,9-10H2,1-4H3,(H,29,31)(H,30,32)/b19-11+,20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177954 (3-(4-chlorophenyl)-N-{2-[3-(4-chlorophenyl)-2-cyan...) Show SMILES Clc1cccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2cccc(Cl)c2)\C#N)c1 Show InChI InChI=1S/C22H16Cl2N4O2/c23-19-5-1-3-15(11-19)9-17(13-25)21(29)27-7-8-28-22(30)18(14-26)10-16-4-2-6-20(24)12-16/h1-6,9-12H,7-8H2,(H,27,29)(H,28,30)/b17-9+,18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177960 (CHEMBL436325 | N-{2-propoxy-3-[2-cyano-3-(3,4-dihy...) Show SMILES CCCOC(CNC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)CNC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C26H26N4O7/c1-2-7-37-20(14-29-25(35)18(12-27)8-16-3-5-21(31)23(33)10-16)15-30-26(36)19(13-28)9-17-4-6-22(32)24(34)11-17/h3-6,8-11,20,31-34H,2,7,14-15H2,1H3,(H,29,35)(H,30,36)/b18-8+,19-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177961 (2-cyano-N-{3-[2-cyano-3-(4-carboxyphenyl)acryloyla...) Show SMILES OC(=O)c1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(cc2)C(O)=O)\C#N)cc1 Show InChI InChI=1S/C25H20N4O6/c26-14-20(12-16-2-6-18(7-3-16)24(32)33)22(30)28-10-1-11-29-23(31)21(15-27)13-17-4-8-19(9-5-17)25(34)35/h2-9,12-13H,1,10-11H2,(H,28,30)(H,29,31)(H,32,33)(H,34,35)/b20-12+,21-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177956 (3-(2-chloro-phenyl)-N-{2-[3-(2-chlorophenyl)-2-cya...) Show SMILES Clc1ccccc1\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c1ccccc1Cl)\C#N Show InChI InChI=1S/C22H16Cl2N4O2/c23-19-7-3-1-5-15(19)11-17(13-25)21(29)27-9-10-28-22(30)18(14-26)12-16-6-2-4-8-20(16)24/h1-8,11-12H,9-10H2,(H,27,29)(H,28,30)/b17-11+,18-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177962 (3-(4-chlorophenyl)-N-{6-[3-(4-chlorophenyl)-2-cyan...) Show SMILES Clc1cccc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2cccc(Cl)c2)\C#N)c1 Show InChI InChI=1S/C26H24Cl2N4O2/c27-23-9-5-7-19(15-23)13-21(17-29)25(33)31-11-3-1-2-4-12-32-26(34)22(18-30)14-20-8-6-10-24(28)16-20/h5-10,13-16H,1-4,11-12H2,(H,31,33)(H,32,34)/b21-13+,22-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177957 (2-cyano-N-{6-[2-cyano-3-(3,4-dimethoxyphenyl)acryl...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2ccc(OC)c(OC)c2)\C#N)cc1OC Show InChI InChI=1S/C30H34N4O6/c1-37-25-11-9-21(17-27(25)39-3)15-23(19-31)29(35)33-13-7-5-6-8-14-34-30(36)24(20-32)16-22-10-12-26(38-2)28(18-22)40-4/h9-12,15-18H,5-8,13-14H2,1-4H3,(H,33,35)(H,34,36)/b23-15+,24-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177958 (2-cyano-N-[4-(2-cyano-3-phenylacryloylamino)butyl]...) Show SMILES O=C(NCCCCNC(=O)C(=C\c1ccccc1)\C#N)C(=C\c1ccccc1)\C#N Show InChI InChI=1S/C24H22N4O2/c25-17-21(15-19-9-3-1-4-10-19)23(29)27-13-7-8-14-28-24(30)22(18-26)16-20-11-5-2-6-12-20/h1-6,9-12,15-16H,7-8,13-14H2,(H,27,29)(H,28,30)/b21-15+,22-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177959 (2-cyano-N-{3-[2-cyano-3-(4-methoxyphenyl)acryloyla...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(OC)cc2)\C#N)cc1 Show InChI InChI=1S/C25H24N4O4/c1-32-22-8-4-18(5-9-22)14-20(16-26)24(30)28-12-3-13-29-25(31)21(17-27)15-19-6-10-23(33-2)11-7-19/h4-11,14-15H,3,12-13H2,1-2H3,(H,28,30)(H,29,31)/b20-14+,21-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177966 (2-cyano-N-{14-[2-cyano-3-(3,4,5-trihydroxyphenyl)a...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCCCCCCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C32H38N4O8/c33-19-23(13-21-15-25(37)29(41)26(38)16-21)31(43)35-11-9-7-5-3-1-2-4-6-8-10-12-36-32(44)24(20-34)14-22-17-27(39)30(42)28(40)18-22/h13-18,37-42H,1-12H2,(H,35,43)(H,36,44)/b23-13+,24-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177967 (2-cyano-N-{5-[2-cyano-3-(3-methoxyphenyl)acryloyla...) Show SMILES COc1cccc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cccc(OC)c2)\C#N)c1 Show InChI InChI=1S/C27H28N4O4/c1-34-24-10-6-8-20(16-24)14-22(18-28)26(32)30-12-4-3-5-13-31-27(33)23(19-29)15-21-9-7-11-25(17-21)35-2/h6-11,14-17H,3-5,12-13H2,1-2H3,(H,30,32)(H,31,33)/b22-14+,23-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177968 (2-cyano-N-[5-(2-cyano-3-phenylacryloylamino)pentyl...) Show SMILES O=C(NCCCCCNC(=O)C(=C\c1ccccc1)\C#N)C(=C\c1ccccc1)\C#N Show InChI InChI=1S/C25H24N4O2/c26-18-22(16-20-10-4-1-5-11-20)24(30)28-14-8-3-9-15-29-25(31)23(19-27)17-21-12-6-2-7-13-21/h1-2,4-7,10-13,16-17H,3,8-9,14-15H2,(H,28,30)(H,29,31)/b22-16+,23-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177969 (2-cyano-N-{2-[2-cyano-3-(4-methoxyphenyl)acryloyla...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2ccc(OC)cc2)\C#N)cc1 Show InChI InChI=1S/C24H22N4O4/c1-31-21-7-3-17(4-8-21)13-19(15-25)23(29)27-11-12-28-24(30)20(16-26)14-18-5-9-22(32-2)10-6-18/h3-10,13-14H,11-12H2,1-2H3,(H,27,29)(H,28,30)/b19-13+,20-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177964 (2-cyano-N-{4-[2-cyano-3-(4-methoxyphenyl)acryloyla...) Show SMILES COc1ccc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2ccc(OC)cc2)\C#N)cc1 Show InChI InChI=1S/C26H26N4O4/c1-33-23-9-5-19(6-10-23)15-21(17-27)25(31)29-13-3-4-14-30-26(32)22(18-28)16-20-7-11-24(34-2)12-8-20/h5-12,15-16H,3-4,13-14H2,1-2H3,(H,29,31)(H,30,32)/b21-15+,22-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50177963 (2-cyano-N-{14-[2-cyano-3-(3,4-dihydroxyphenyl)acry...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O Show InChI InChI=1S/C32H38N4O6/c33-21-25(17-23-11-13-27(37)29(39)19-23)31(41)35-15-9-7-5-3-1-2-4-6-8-10-16-36-32(42)26(22-34)18-24-12-14-28(38)30(40)20-24/h11-14,17-20,37-40H,1-10,15-16H2,(H,35,41)(H,36,42)/b25-17+,26-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair

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