Compile Data Set for Download or QSAR

Found 183 hits with Last Name = 'grillo' and Initial = 'mp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019064 (CHEMBL3288340) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C16H15F3N2OS/c17-16(18,19)13-4-2-1-3-12(13)11-5-8-21(9-6-11)15(22)14-20-7-10-23-14/h1-4,7,10-11H,5-6,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019040 (CHEMBL1230001) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019043 (CHEMBL3288142) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19ClF3N3O2/c1-28-17-7-6-13(20)12-15(17)24-18(27)26-10-8-25(9-11-26)16-5-3-2-4-14(16)19(21,22)23/h2-7,12H,8-11H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019044 (CHEMBL3288337) Show SMILES Cn1cnc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H18F3N3O/c1-22-10-15(21-11-22)16(24)23-8-6-12(7-9-23)13-4-2-3-5-14(13)17(18,19)20/h2-5,10-12H,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019039 (CHEMBL3288342) Show SMILES COC(=O)c1ccccc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C21H21F3N2O3/c1-29-19(27)16-7-3-5-9-18(16)25-20(28)26-12-10-14(11-13-26)15-6-2-4-8-17(15)21(22,23)24/h2-9,14H,10-13H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019045 (CHEMBL3288331) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H20ClF3N2O2/c1-28-18-7-6-14(21)12-17(18)25-19(27)26-10-8-13(9-11-26)15-4-2-3-5-16(15)20(22,23)24/h2-7,12-13H,8-11H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019062 (CHEMBL3288146) Show SMILES FC(F)(F)c1cccc(CN2CCN(CC2)c2ncnc3sc4CCCc4c23)c1 Show InChI InChI=1S/C21H21F3N4S/c22-21(23,24)15-4-1-3-14(11-15)12-27-7-9-28(10-8-27)19-18-16-5-2-6-17(16)29-20(18)26-13-25-19/h1,3-4,11,13H,2,5-10,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019063 (CHEMBL3288336) Show SMILES FC(F)(F)c1ccnc(n1)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H15F6N3/c18-16(19,20)13-4-2-1-3-12(13)11-6-9-26(10-7-11)15-24-8-5-14(25-15)17(21,22)23/h1-5,8,11H,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019064 (CHEMBL3288340) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C16H15F3N2OS/c17-16(18,19)13-4-2-1-3-12(13)11-5-8-21(9-6-11)15(22)14-20-7-10-23-14/h1-4,7,10-11H,5-6,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019065 (CHEMBL3288341) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C17H16F3NO2/c18-17(19,20)14-5-2-1-4-13(14)12-7-9-21(10-8-12)16(22)15-6-3-11-23-15/h1-6,11-12H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019066 (CHEMBL3288147) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C22H21F3N4OS/c23-22(24,25)16-6-2-1-4-14(16)12-18(30)28-8-10-29(11-9-28)20-19-15-5-3-7-17(15)31-21(19)27-13-26-20/h1-2,4,6,13H,3,5,7-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019043 (CHEMBL3288142) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19ClF3N3O2/c1-28-17-7-6-13(20)12-15(17)24-18(27)26-10-8-25(9-11-26)16-5-3-2-4-14(16)19(21,22)23/h2-7,12H,8-11H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019041 (CHEMBL3288335) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1cnccc1C(F)(F)F Show InChI InChI=1S/C19H16F6N2O/c20-18(21,22)15-4-2-1-3-13(15)12-6-9-27(10-7-12)17(28)14-11-26-8-5-16(14)19(23,24)25/h1-5,8,11-12H,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019040 (CHEMBL1230001) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019039 (CHEMBL3288342) Show SMILES COC(=O)c1ccccc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C21H21F3N2O3/c1-29-19(27)16-7-3-5-9-18(16)25-20(28)26-12-10-14(11-13-26)15-6-2-4-8-17(15)21(22,23)24/h2-9,14H,10-13H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019044 (CHEMBL3288337) Show SMILES Cn1cnc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H18F3N3O/c1-22-10-15(21-11-22)16(24)23-8-6-12(7-9-23)13-4-2-3-5-14(13)17(18,19)20/h2-5,10-12H,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019065 (CHEMBL3288341) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C17H16F3NO2/c18-17(19,20)14-5-2-1-4-13(14)12-7-9-21(10-8-12)16(22)15-6-3-11-23-15/h1-6,11-12H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019067 (CHEMBL3288339) Show SMILES FC(F)(F)c1cc(n[nH]1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H15F6N3O/c18-16(19,20)12-4-2-1-3-11(12)10-5-7-26(8-6-10)15(27)13-9-14(25-24-13)17(21,22)23/h1-4,9-10H,5-8H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019041 (CHEMBL3288335) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1cnccc1C(F)(F)F Show InChI InChI=1S/C19H16F6N2O/c20-18(21,22)15-4-2-1-3-13(15)12-6-9-27(10-7-12)17(28)14-11-26-8-5-16(14)19(23,24)25/h1-5,8,11-12H,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019068 (CHEMBL3288136) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C18H18ClF3N4O2/c1-28-15-5-4-12(19)11-14(15)24-17(27)26-9-7-25(8-10-26)16-13(18(20,21)22)3-2-6-23-16/h2-6,11H,7-10H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019045 (CHEMBL3288331) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H20ClF3N2O2/c1-28-18-7-6-14(21)12-17(18)25-19(27)26-10-8-13(9-11-26)15-4-2-3-5-16(15)20(22,23)24/h2-7,12-13H,8-11H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019068 (CHEMBL3288136) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C18H18ClF3N4O2/c1-28-15-5-4-12(19)11-14(15)24-17(27)26-9-7-25(8-10-26)16-13(18(20,21)22)3-2-6-23-16/h2-6,11H,7-10H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019067 (CHEMBL3288339) Show SMILES FC(F)(F)c1cc(n[nH]1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H15F6N3O/c18-16(19,20)12-4-2-1-3-11(12)10-5-7-26(8-6-10)15(27)13-9-14(25-24-13)17(21,22)23/h1-4,9-10H,5-8H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019063 (CHEMBL3288336) Show SMILES FC(F)(F)c1ccnc(n1)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H15F6N3/c18-16(19,20)13-4-2-1-3-12(13)11-6-9-26(10-7-11)15-24-8-5-14(25-15)17(21,22)23/h1-5,8,11H,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019066 (CHEMBL3288147) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C22H21F3N4OS/c23-22(24,25)16-6-2-1-4-14(16)12-18(30)28-8-10-29(11-9-28)20-19-15-5-3-7-17(15)31-21(19)27-13-26-20/h1-2,4,6,13H,3,5,7-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019069 (CHEMBL3288149) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1C)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H20ClF3N4O2/c1-12-11-26(17-14(19(21,22)23)4-3-7-24-17)8-9-27(12)18(28)25-15-10-13(20)5-6-16(15)29-2/h3-7,10,12H,8-9,11H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019070 (CHEMBL3288143) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C21H22ClN5O2S/c1-29-16-6-5-13(22)11-15(16)25-21(28)27-9-7-26(8-10-27)19-18-14-3-2-4-17(14)30-20(18)24-12-23-19/h5-6,11-12H,2-4,7-10H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019071 (CHEMBL3288135) Show SMILES Clc1ccccc1N1CCN(CC1)C(=O)c1cn(Cc2ccccc2)cn1 Show InChI InChI=1S/C21H21ClN4O/c22-18-8-4-5-9-20(18)25-10-12-26(13-11-25)21(27)19-15-24(16-23-19)14-17-6-2-1-3-7-17/h1-9,15-16H,10-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019069 (CHEMBL3288149) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1C)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H20ClF3N4O2/c1-12-11-26(17-14(19(21,22)23)4-3-7-24-17)8-9-27(12)18(28)25-15-10-13(20)5-6-16(15)29-2/h3-7,10,12H,8-9,11H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019072 (CHEMBL3288330) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H20ClF3N4O2/c1-29-16-6-5-13(20)12-15(16)25-18(28)27-9-3-8-26(10-11-27)17-14(19(21,22)23)4-2-7-24-17/h2,4-7,12H,3,8-11H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019073 (CHEMBL3288338) Show SMILES Cn1cncc1C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H18F3N3O/c1-22-11-21-10-15(22)16(24)23-8-6-12(7-9-23)13-4-2-3-5-14(13)17(18,19)20/h2-5,10-12H,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019070 (CHEMBL3288143) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C21H22ClN5O2S/c1-29-16-6-5-13(22)11-15(16)25-21(28)27-9-7-26(8-10-27)19-18-14-3-2-4-17(14)30-20(18)24-12-23-19/h5-6,11-12H,2-4,7-10H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019074 (CHEMBL3288334) Show SMILES COC(=O)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C21H20F3NO3/c1-28-20(27)16-6-4-5-15(13-16)19(26)25-11-9-14(10-12-25)17-7-2-3-8-18(17)21(22,23)24/h2-8,13-14H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019062 (CHEMBL3288146) Show SMILES FC(F)(F)c1cccc(CN2CCN(CC2)c2ncnc3sc4CCCc4c23)c1 Show InChI InChI=1S/C21H21F3N4S/c22-21(23,24)15-4-1-3-14(11-15)12-27-7-9-28(10-8-27)19-18-16-5-2-6-17(16)29-20(18)26-13-25-19/h1,3-4,11,13H,2,5-10,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019072 (CHEMBL3288330) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H20ClF3N4O2/c1-29-16-6-5-13(20)12-15(16)25-18(28)27-9-3-8-26(10-11-27)17-14(19(21,22)23)4-2-7-24-17/h2,4-7,12H,3,8-11H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019074 (CHEMBL3288334) Show SMILES COC(=O)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C21H20F3NO3/c1-28-20(27)16-6-4-5-15(13-16)19(26)25-11-9-14(10-12-25)17-7-2-3-8-18(17)21(22,23)24/h2-8,13-14H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019075 (CHEMBL3288150) Show SMILES COc1ccc(Cl)cc1C(=O)N1CCN(C(C)C1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C22H23ClN4O2S/c1-13-11-26(22(28)16-10-14(23)6-7-17(16)29-2)8-9-27(13)20-19-15-4-3-5-18(15)30-21(19)25-12-24-20/h6-7,10,12-13H,3-5,8-9,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019073 (CHEMBL3288338) Show SMILES Cn1cncc1C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H18F3N3O/c1-22-11-21-10-15(22)16(24)23-8-6-12(7-9-23)13-4-2-3-5-14(13)17(18,19)20/h2-5,10-12H,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019076 (CHEMBL3288141) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C18H19Cl2N3O2/c1-25-17-7-6-13(19)12-15(17)21-18(24)23-10-8-22(9-11-23)16-5-3-2-4-14(16)20/h2-7,12H,8-11H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019077 (CHEMBL3288333) Show SMILES FC(F)(F)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17F6NO/c21-19(22,23)15-5-3-4-14(12-15)18(28)27-10-8-13(9-11-27)16-6-1-2-7-17(16)20(24,25)26/h1-7,12-13H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019078 (CHEMBL3288332) Show SMILES COc1ccc(Cl)cc1NC(=O)C1CCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H19ClF3N3O2/c1-28-16-5-4-13(20)11-15(16)25-18(27)12-6-9-26(10-7-12)17-14(19(21,22)23)3-2-8-24-17/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019076 (CHEMBL3288141) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C18H19Cl2N3O2/c1-25-17-7-6-13(19)12-15(17)21-18(24)23-10-8-22(9-11-23)16-5-3-2-4-14(16)20/h2-7,12H,8-11H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019075 (CHEMBL3288150) Show SMILES COc1ccc(Cl)cc1C(=O)N1CCN(C(C)C1)c1ncnc2sc3CCCc3c12 Show InChI InChI=1S/C22H23ClN4O2S/c1-13-11-26(22(28)16-10-14(23)6-7-17(16)29-2)8-9-27(13)20-19-15-4-3-5-18(15)30-21(19)25-12-24-20/h6-7,10,12-13H,3-5,8-9,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019079 (CHEMBL3288137) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H17ClF6N4O2/c1-32-15-3-2-12(20)9-14(15)28-17(31)30-6-4-29(5-7-30)16-13(19(24,25)26)8-11(10-27-16)18(21,22)23/h2-3,8-10H,4-7H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019080 (CHEMBL3288138) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ncccc1Cl Show InChI InChI=1S/C17H18Cl2N4O2/c1-25-15-5-4-12(18)11-14(15)21-17(24)23-9-7-22(8-10-23)16-13(19)3-2-6-20-16/h2-6,11H,7-10H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019077 (CHEMBL3288333) Show SMILES FC(F)(F)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17F6NO/c21-19(22,23)15-5-3-4-14(12-15)18(28)27-10-8-13(9-11-27)16-6-1-2-7-17(16)20(24,25)26/h1-7,12-13H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019038 (CHEMBL3288151) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(C(=O)C1)c1ccccc1Cl Show InChI InChI=1S/C18H17Cl2N3O3/c1-26-16-7-6-12(19)10-14(16)21-18(25)22-8-9-23(17(24)11-22)15-5-3-2-4-13(15)20/h2-7,10H,8-9,11H2,1H3,(H,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019034 (CHEMBL3288148) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)c1ncccc1C(F)(F)F Show InChI InChI=1S/C19H17F6N3O/c20-18(21,22)14-5-2-1-4-13(14)12-16(29)27-8-10-28(11-9-27)17-15(19(23,24)25)6-3-7-26-17/h1-7H,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019081 (CHEMBL3288144) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(Cc2c(Cl)cccc2Cl)CC1 Show InChI InChI=1S/C19H20Cl3N3O2/c1-27-18-6-5-13(20)11-17(18)23-19(26)25-9-7-24(8-10-25)12-14-15(21)3-2-4-16(14)22/h2-6,11H,7-10,12H2,1H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019081 (CHEMBL3288144) Show SMILES COc1ccc(Cl)cc1NC(=O)N1CCN(Cc2c(Cl)cccc2Cl)CC1 Show InChI InChI=1S/C19H20Cl3N3O2/c1-27-18-6-5-13(20)11-17(18)23-19(26)25-9-7-24(8-10-25)12-14-15(21)3-2-4-16(14)22/h2-6,11H,7-10,12H2,1H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair

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