Compile Data Set for Download or QSAR

Found 132 hits with Last Name = 'haeggström' and Initial = 'jz'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23986 (3,4-dihydro-1H-2-benzothiopyran-3-one | isothiochr...) Show SMILES O=C1Cc2ccccc2CS1 Show InChI InChI=1S/C9H8OS/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-4H,5-6H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23983 (3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...) Show SMILES NC1Cc2ccccc2CC1C(=O)NO Show InChI InChI=1S/C11H14N2O2/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(14)13-15/h1-4,9-10,15H,5-6,12H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23987 (2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...) Show SMILES ON1Cc2ccccc2CC1=O Show InChI InChI=1S/C9H9NO2/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,12H,5-6H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23983 (3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...) Show SMILES NC1Cc2ccccc2CC1C(=O)NO Show InChI InChI=1S/C11H14N2O2/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(14)13-15/h1-4,9-10,15H,5-6,12H2,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM23978 ((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCc1ccccc1 Show InChI InChI=1S/C19H22N2O/c20-18-13-16-10-4-5-11-17(16)14-19(18)21-22-12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18H,6,9,12-14,20H2/b21-19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM23979 ((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O/c21-19-14-17-11-4-5-12-18(17)15-20(19)22-23-13-7-6-10-16-8-2-1-3-9-16/h1-5,8-9,11-12,19H,6-7,10,13-15,21H2/b22-20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23983 (3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...) Show SMILES NC1Cc2ccccc2CC1C(=O)NO Show InChI InChI=1S/C11H14N2O2/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(14)13-15/h1-4,9-10,15H,5-6,12H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+4	-29.0	n/a	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM23980 ((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O/c22-20-15-18-12-6-7-13-19(18)16-21(20)23-24-14-8-2-5-11-17-9-3-1-4-10-17/h1,3-4,6-7,9-10,12-13,20H,2,5,8,11,14-16,22H2/b23-21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23979 ((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O/c21-19-14-17-11-4-5-12-18(17)15-20(19)22-23-13-7-6-10-16-8-2-1-3-9-16/h1-5,8-9,11-12,19H,6-7,10,13-15,21H2/b22-20-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23990 (3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...) Show SMILES NC1Cc2ccccc2NC1=O Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23980 ((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O/c22-20-15-18-12-6-7-13-19(18)16-21(20)23-24-14-8-2-5-11-17-9-3-1-4-10-17/h1,3-4,6-7,9-10,12-13,20H,2,5,8,11,14-16,22H2/b23-21-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23978 ((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCc1ccccc1 Show InChI InChI=1S/C19H22N2O/c20-18-13-16-10-4-5-11-17(16)14-19(18)21-22-12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18H,6,9,12-14,20H2/b21-19-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23975 ((3Z)-3-(methoxyimino)-1,2,3,4-tetrahydronaphthalen...) Show SMILES CO\N=C1\Cc2ccccc2CC1N Show InChI InChI=1S/C11H14N2O/c1-14-13-11-7-9-5-3-2-4-8(9)6-10(11)12/h2-5,10H,6-7,12H2,1H3/b13-11-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23977 ((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCc1ccccc1 Show InChI InChI=1S/C18H20N2O/c19-17-12-15-8-4-5-9-16(15)13-18(17)20-21-11-10-14-6-2-1-3-7-14/h1-9,17H,10-13,19H2/b20-18-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24285 ((3S)-3-amino-5-[(4-phenoxyphenyl)carbamoyl]pentano...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)CC(O)=O |r| Show InChI InChI=1S/C18H20N2O4/c19-13(12-18(22)23)6-11-17(21)20-14-7-9-16(10-8-14)24-15-4-2-1-3-5-15/h1-5,7-10,13H,6,11-12,19H2,(H,20,21)(H,22,23)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24282 ((2S)-2-amino-N-[4-(4-methylphenoxy)phenyl]pentaned...) Show SMILES Cc1ccc(Oc2ccc(NC(=O)CC[C@H](N)C(N)=O)cc2)cc1 |r| Show InChI InChI=1S/C18H21N3O3/c1-12-2-6-14(7-3-12)24-15-8-4-13(5-9-15)21-17(22)11-10-16(19)18(20)23/h2-9,16H,10-11,19H2,1H3,(H2,20,23)(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24291 ((4S)-4-amino-5-hydroxy-N-(4-phenoxyphenyl)pentanam...) Show SMILES N[C@H](CO)CCC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C17H20N2O3/c18-13(12-20)6-11-17(21)19-14-7-9-16(10-8-14)22-15-4-2-1-3-5-15/h1-5,7-10,13,20H,6,11-12,18H2,(H,19,21)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24287 (3-[(2S)-2-amino-N-(4-phenoxyphenyl)pentanediamido]...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C20H23N3O5/c21-17(20(27)22-13-12-19(25)26)10-11-18(24)23-14-6-8-16(9-7-14)28-15-4-2-1-3-5-15/h1-9,17H,10-13,21H2,(H,22,27)(H,23,24)(H,25,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24277 ((2S)-2-amino-4-{[4-(2-hydroxy-2-phenylethoxy)pheny...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCC(O)c2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C19H22N2O5/c20-16(19(24)25)10-11-18(23)21-14-6-8-15(9-7-14)26-12-17(22)13-4-2-1-3-5-13/h1-9,16-17,22H,10-12,20H2,(H,21,23)(H,24,25)/t16-,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24276 ((2S)-2-amino-4-{[4-(2-oxo-2-phenylethoxy)phenyl]ca...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCC(=O)c2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C19H20N2O5/c20-16(19(24)25)10-11-18(23)21-14-6-8-15(9-7-14)26-12-17(22)13-4-2-1-3-5-13/h1-9,16H,10-12,20H2,(H,21,23)(H,24,25)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24270 ((2S)-2-amino-4-[(4-phenoxyphenyl)carbamoyl]butanoi...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18N2O4/c18-15(17(21)22)10-11-16(20)19-12-6-8-14(9-7-12)23-13-4-2-1-3-5-13/h1-9,15H,10-11,18H2,(H,19,20)(H,21,22)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24288 (4-[(2S)-2-amino-N-(4-phenoxyphenyl)pentanediamido]...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)NCCCC(O)=O |r| Show InChI InChI=1S/C21H25N3O5/c22-18(21(28)23-14-4-7-20(26)27)12-13-19(25)24-15-8-10-17(11-9-15)29-16-5-2-1-3-6-16/h1-3,5-6,8-11,18H,4,7,12-14,22H2,(H,23,28)(H,24,25)(H,26,27)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24289 ((2S)-2-amino-N-(2-hydroxyethyl)-N'-(4-phenoxypheny...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)NCCO |r| Show InChI InChI=1S/C19H23N3O4/c20-17(19(25)21-12-13-23)10-11-18(24)22-14-6-8-16(9-7-14)26-15-4-2-1-3-5-15/h1-9,17,23H,10-13,20H2,(H,21,25)(H,22,24)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24256 ((2S)-2-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}but...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C18H20N2O4/c19-16(18(22)23)10-11-17(21)20-14-6-8-15(9-7-14)24-12-13-4-2-1-3-5-13/h1-9,16H,10-12,19H2,(H,20,21)(H,22,23)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24292 ((4S)-4,5-diamino-N-(4-phenoxyphenyl)pentanamide | ...) Show SMILES NC[C@@H](N)CCC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C17H21N3O2/c18-12-13(19)6-11-17(21)20-14-7-9-16(10-8-14)22-15-4-2-1-3-5-15/h1-5,7-10,13H,6,11-12,18-19H2,(H,20,21)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24271 ((2S)-2-amino-N-(4-benzylphenyl)pentanediamide | Mo...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Cc2ccccc2)cc1)C(N)=O |r| Show InChI InChI=1S/C18H21N3O2/c19-16(18(20)23)10-11-17(22)21-15-8-6-14(7-9-15)12-13-4-2-1-3-5-13/h1-9,16H,10-12,19H2,(H2,20,23)(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24290 ((2S)-2-amino-N-(2-aminoethyl)-N'-(4-phenoxyphenyl)...) Show SMILES NCCNC(=O)[C@@H](N)CCC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C19H24N4O3/c20-12-13-22-19(25)17(21)10-11-18(24)23-14-6-8-16(9-7-14)26-15-4-2-1-3-5-15/h1-9,17H,10-13,20-21H2,(H,22,25)(H,23,24)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24283 ((2S)-2-amino-4-({4-[4-(1H-pyrrol-1-yl)phenoxy]phen...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccc(cc2)-n2cccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C21H21N3O4/c22-19(21(26)27)11-12-20(25)23-15-3-7-17(8-4-15)28-18-9-5-16(6-10-18)24-13-1-2-14-24/h1-10,13-14,19H,11-12,22H2,(H,23,25)(H,26,27)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24286 (2-[(2S)-2-amino-N-(4-phenoxyphenyl)pentanediamido]...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C19H21N3O5/c20-16(19(26)21-12-18(24)25)10-11-17(23)22-13-6-8-15(9-7-13)27-14-4-2-1-3-5-14/h1-9,16H,10-12,20H2,(H,21,26)(H,22,23)(H,24,25)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24261 ((2S)-2-amino-N-[4-(benzyloxy)phenyl]pentanediamide...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCc2ccccc2)cc1)C(N)=O |r| Show InChI InChI=1S/C18H21N3O3/c19-16(18(20)23)10-11-17(22)21-14-6-8-15(9-7-14)24-12-13-4-2-1-3-5-13/h1-9,16H,10-12,19H2,(H2,20,23)(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24262 ((2S)-2-amino-N-[4-(benzyloxy)phenyl]-N'-hydroxypen...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C18H21N3O4/c19-16(18(23)21-24)10-11-17(22)20-14-6-8-15(9-7-14)25-12-13-4-2-1-3-5-13/h1-9,16,24H,10-12,19H2,(H,20,22)(H,21,23)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24284 ((2S)-2-amino-N-{4-[4-(furan-3-yl)phenoxy]phenyl}pe...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccc(cc2)-c2ccoc2)cc1)C(N)=O |r| Show InChI InChI=1S/C21H21N3O4/c22-19(21(23)26)9-10-20(25)24-16-3-7-18(8-4-16)28-17-5-1-14(2-6-17)15-11-12-27-13-15/h1-8,11-13,19H,9-10,22H2,(H2,23,26)(H,24,25)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24275 ((2S)-2-amino-4-{[4-(3-phenylpropoxy)phenyl]carbamo...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCCCc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O4/c21-18(20(24)25)12-13-19(23)22-16-8-10-17(11-9-16)26-14-4-7-15-5-2-1-3-6-15/h1-3,5-6,8-11,18H,4,7,12-14,21H2,(H,22,23)(H,24,25)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24259 (Modified amino acid analog, 6a | methyl (2S)-2-ami...) Show SMILES COC(=O)[C@@H](N)CCC(=O)Nc1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C19H22N2O4/c1-24-19(23)17(20)11-12-18(22)21-15-7-9-16(10-8-15)25-13-14-5-3-2-4-6-14/h2-10,17H,11-13,20H2,1H3,(H,21,22)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24274 ((2S)-2-amino-4-{[4-(2-phenylethoxy)phenyl]carbamoy...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCCc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C19H22N2O4/c20-17(19(23)24)10-11-18(22)21-15-6-8-16(9-7-15)25-13-12-14-4-2-1-3-5-14/h1-9,17H,10-13,20H2,(H,21,22)(H,23,24)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24260 (Modified amino acid analog, 6b | tert-butyl (2S)-2...) Show SMILES CC(C)(C)OC(=O)[C@@H](N)CCC(=O)Nc1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C22H28N2O4/c1-22(2,3)28-21(26)19(23)13-14-20(25)24-17-9-11-18(12-10-17)27-15-16-7-5-4-6-8-16/h4-12,19H,13-15,23H2,1-3H3,(H,24,25)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24263 (4-amino-N-[4-(benzyloxy)phenyl]butanamide | Modifi...) Show SMILES NCCCC(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H20N2O2/c18-12-4-7-17(20)19-15-8-10-16(11-9-15)21-13-14-5-2-1-3-6-14/h1-3,5-6,8-11H,4,7,12-13,18H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24298 ((4S)-4-amino-5-(1,3-dioxo-2,3-dihydro-1H-isoindol-...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)CN1C(=O)c2ccccc2C1=O |r| Show InChI InChI=1S/C25H23N3O4/c26-17(16-28-24(30)21-8-4-5-9-22(21)25(28)31)10-15-23(29)27-18-11-13-20(14-12-18)32-19-6-2-1-3-7-19/h1-9,11-14,17H,10,15-16,26H2,(H,27,29)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24294 ((2S)-2-amino-4-[(4-phenoxyphenyl)carbamoyl]butane-...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)CS(O)(=O)=O |r| Show InChI InChI=1S/C17H20N2O5S/c18-13(12-25(21,22)23)6-11-17(20)19-14-7-9-16(10-8-14)24-15-4-2-1-3-5-15/h1-5,7-10,13H,6,11-12,18H2,(H,19,20)(H,21,22,23)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24244 ((2S)-2-amino-N-[4-(benzyloxy)phenyl]propanamide | ...) Show SMILES C[C@H](N)C(=O)Nc1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C16H18N2O2/c1-12(17)16(19)18-14-7-9-15(10-8-14)20-11-13-5-3-2-4-6-13/h2-10,12H,11,17H2,1H3,(H,18,19)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24281 ((2S)-2-amino-N-[4-(3-methylphenoxy)phenyl]pentaned...) Show SMILES Cc1cccc(Oc2ccc(NC(=O)CC[C@H](N)C(N)=O)cc2)c1 |r| Show InChI InChI=1S/C18H21N3O3/c1-12-3-2-4-15(11-12)24-14-7-5-13(6-8-14)21-17(22)10-9-16(19)18(20)23/h2-8,11,16H,9-10,19H2,1H3,(H2,20,23)(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24272 ((2S)-2-amino-4-{[4-(phenylamino)phenyl]carbamoyl}b...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Nc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C17H19N3O3/c18-15(17(22)23)10-11-16(21)20-14-8-6-13(7-9-14)19-12-4-2-1-3-5-12/h1-9,15,19H,10-11,18H2,(H,20,21)(H,22,23)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24243 (2-amino-N-[4-(benzyloxy)phenyl]acetamide | Amino a...) Show SMILES NCC(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O2/c16-10-15(18)17-13-6-8-14(9-7-13)19-11-12-4-2-1-3-5-12/h1-9H,10-11,16H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24296 ((4S)-4-amino-5-[(5-amino-1,3,4-thiadiazol-2-yl)sul...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)CSc1nnc(N)s1 |r| Show InChI InChI=1S/C19H21N5O2S2/c20-13(12-27-19-24-23-18(21)28-19)6-11-17(25)22-14-7-9-16(10-8-14)26-15-4-2-1-3-5-15/h1-5,7-10,13H,6,11-12,20H2,(H2,21,23)(H,22,25)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24297 ((4S)-4-amino-N-(4-phenoxyphenyl)-5-(1H-pyrrol-1-yl...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)Cn1cccc1 |r| Show InChI InChI=1S/C21H23N3O2/c22-17(16-24-14-4-5-15-24)8-13-21(25)23-18-9-11-20(12-10-18)26-19-6-2-1-3-7-19/h1-7,9-12,14-15,17H,8,13,16,22H2,(H,23,25)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aminopeptidase N (Sus scrofa (Pig))	BDBM23973 (3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...) Show SMILES NC1Cc2ccccc2CC1=O Show InChI InChI=1S/C10H11NO/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,9H,5-6,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24251 ((4S)-4-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}but...) Show SMILES N[C@@H](CCC(O)=O)C(=O)Nc1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C18H20N2O4/c19-16(10-11-17(21)22)18(23)20-14-6-8-15(9-7-14)24-12-13-4-2-1-3-5-13/h1-9,16H,10-12,19H2,(H,20,23)(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair

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