Compile Data Set for Download or QSAR

Found 36 hits with Last Name = 'hamaguchi' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50103634 (CL-287389 | FK-235 | Nilvadipine | Nivadipine | SK...) Show SMILES COC(=O)C1=C(NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C)C#N |c:8,t:4| Show InChI InChI=1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50227967 (CHEMBL78973) Show SMILES CC(C)OC(=O)C1=C(C)N=C(C)N(C1c1ccccc1[N+]([O-])=O)C(=O)OCCN(Cc1ccccc1)Cc1ccc(Cl)c(Cl)c1 |c:6,t:9| Show InChI InChI=1S/C33H34Cl2N4O6/c1-21(2)45-32(40)30-22(3)36-23(4)38(31(30)26-12-8-9-13-29(26)39(42)43)33(41)44-17-16-37(19-24-10-6-5-7-11-24)20-25-14-15-27(34)28(35)18-25/h5-15,18,21,31H,16-17,19-20H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50101817 (Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC |c:4,9| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50101815 (CHEBI:7550 | Nicardipine) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCN(C)Cc1ccccc1 |c:4,9| Show InChI InChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50227968 (CHEMBL310953) Show SMILES CC(C)OC(=O)C1=C(C)N=C(C)N(C1c1ccccc1[N+]([O-])=O)C(=O)OCCN(Cc1ccccc1)Cc1ccc2ccccc2c1 |c:6,t:9| Show InChI InChI=1S/C37H38N4O6/c1-25(2)47-36(42)34-26(3)38-27(4)40(35(34)32-16-10-11-17-33(32)41(44)45)37(43)46-21-20-39(23-28-12-6-5-7-13-28)24-29-18-19-30-14-8-9-15-31(30)22-29/h5-19,22,25,35H,20-21,23-24H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50227969 (CHEMBL312176 | CV-4093) Show SMILES CO\C(O)=C1/C(C(C(=O)OCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |c:36,t:33| Show InChI InChI=1S/C35H38N4O6/c1-24-30(34(40)44-3)32(28-15-10-16-29(23-28)39(42)43)31(25(2)36-24)35(41)45-22-21-37-17-19-38(20-18-37)33(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-16,23,32-33,40H,17-22H2,1-3H3/b34-30-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCCCCCn2ccnc2)cc1O Show InChI InChI=1S/C21H25N3O4/c22-15-18(13-17-7-8-19(25)20(26)14-17)21(27)28-12-6-4-2-1-3-5-10-24-11-9-23-16-24/h7-9,11,13-14,16,25-26H,1-6,10,12H2/b18-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O Show InChI InChI=1S/C18H16N2O4/c19-11-15(9-14-5-6-16(21)17(22)10-14)18(23)24-8-2-4-13-3-1-7-20-12-13/h1,3,5-7,9-10,12,21-22H,2,4,8H2/b15-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O Show InChI InChI=1S/C18H16N2O4/c19-11-15(9-14-5-6-16(21)17(22)10-14)18(23)24-8-2-4-13-3-1-7-20-12-13/h1,3,5-7,9-10,12,21-22H,2,4,8H2/b15-9+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCCCCCn2ccnc2)cc1O Show InChI InChI=1S/C21H25N3O4/c22-15-18(13-17-7-8-19(25)20(26)14-17)21(27)28-12-6-4-2-1-3-5-10-24-11-9-23-16-24/h7-9,11,13-14,16,25-26H,1-6,10,12H2/b18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCCCCCn2ccnc2)cc1O Show InChI InChI=1S/C21H25N3O4/c22-15-18(13-17-7-8-19(25)20(26)14-17)21(27)28-12-6-4-2-1-3-5-10-24-11-9-23-16-24/h7-9,11,13-14,16,25-26H,1-6,10,12H2/b18-13+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O Show InChI InChI=1S/C18H16N2O4/c19-11-15(9-14-5-6-16(21)17(22)10-14)18(23)24-8-2-4-13-3-1-7-20-12-13/h1,3,5-7,9-10,12,21-22H,2,4,8H2/b15-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair