Compile Data Set for Download or QSAR

Found 266 hits with Last Name = 'haque' and Initial = 'le'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035810 (CHEMBL3359927) Show SMILES C[C@]1(F)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H17FN4O/c1-14(15)6-2-5-11(14)18-12-9(13(16)20)8-17-19-7-3-4-10(12)19/h3-4,7-8,11,18H,2,5-6H2,1H3,(H2,16,20)/t11-,14+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035810 (CHEMBL3359927) Show SMILES C[C@]1(F)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H17FN4O/c1-14(15)6-2-5-11(14)18-12-9(13(16)20)8-17-19-7-3-4-10(12)19/h3-4,7-8,11,18H,2,5-6H2,1H3,(H2,16,20)/t11-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035849 (CHEMBL3359915) Show SMILES C[C@@]1(O)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)12(6-7-16(15,3)22)19-13-10(14(17)21)9-18-20-8-4-5-11(13)20/h4-5,8-9,12,19,22H,6-7H2,1-3H3,(H2,17,21)/t12-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM205027 (US9249096, 40) Show SMILES OC1=C(CN(Cc2ccccc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H20Cl2N2O3/c22-17-9-8-14(11-18(17)23)7-4-10-24-20(27)16-13-25(21(28)19(16)26)12-15-5-2-1-3-6-15/h1-3,5-6,8-9,11,26H,4,7,10,12-13H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035814 (CHEMBL3359921) Show SMILES C[C@]1(N)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H23N5O/c1-15(2)12(6-7-16(15,3)18)20-13-10(14(17)22)9-19-21-8-4-5-11(13)21/h4-5,8-9,12,20H,6-7,18H2,1-3H3,(H2,17,22)/t12-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035842 (CHEMBL3359908) Show SMILES CC1(C)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O/c1-15(2)7-3-6-12(15)18-13-10(14(16)20)9-17-19-8-4-5-11(13)19/h4-5,8-9,12,18H,3,6-7H2,1-2H3,(H2,16,20)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458638 (CHEMBL4203395) Show SMILES OC1=C(CN(CCOc2ccccc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C22H22Cl2N2O4/c23-18-9-8-15(13-19(18)24)5-4-10-25-21(28)17-14-26(22(29)20(17)27)11-12-30-16-6-2-1-3-7-16/h1-3,6-9,13,27H,4-5,10-12,14H2,(H,25,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035847 (CHEMBL3359913) Show SMILES CC1(C)[C@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(2)11(5-6-12(15)20)18-13-9(14(16)21)8-17-19-7-3-4-10(13)19/h3-4,7-8,11-12,18,20H,5-6H2,1-2H3,(H2,16,21)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035837 (CHEMBL3359926) Show SMILES C[C@@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N |r| Show InChI InChI=1S/C15H17N5O/c1-15(9-16)6-2-5-12(15)19-13-10(14(17)21)8-18-20-7-3-4-11(13)20/h3-4,7-8,12,19H,2,5-6H2,1H3,(H2,17,21)/t12-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035849 (CHEMBL3359915) Show SMILES C[C@@]1(O)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)12(6-7-16(15,3)22)19-13-10(14(17)21)9-18-20-8-4-5-11(13)20/h4-5,8-9,12,19,22H,6-7H2,1-3H3,(H2,17,21)/t12-,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035842 (CHEMBL3359908) Show SMILES CC1(C)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O/c1-15(2)7-3-6-12(15)18-13-10(14(16)20)9-17-19-8-4-5-11(13)19/h4-5,8-9,12,18H,3,6-7H2,1-2H3,(H2,16,20)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035841 (CHEMBL3359907) Show SMILES C[C@@H](Nc1c(cnn2cccc12)C(N)=O)C(C)(C)C |r| Show InChI InChI=1S/C14H20N4O/c1-9(14(2,3)4)17-12-10(13(15)19)8-16-18-7-5-6-11(12)18/h5-9,17H,1-4H3,(H2,15,19)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035810 (CHEMBL3359927) Show SMILES C[C@]1(F)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H17FN4O/c1-14(15)6-2-5-11(14)18-12-9(13(16)20)8-17-19-7-3-4-10(12)19/h3-4,7-8,11,18H,2,5-6H2,1H3,(H2,16,20)/t11-,14+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458637 (CHEMBL4210998) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NC)C1=O |t:19| Show InChI InChI=1S/C17H21Cl2N3O2/c1-3-22-10-12(15(20-2)17(22)24)16(23)21-8-4-5-11-6-7-13(18)14(19)9-11/h6-7,9,20H,3-5,8,10H2,1-2H3,(H,21,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035837 (CHEMBL3359926) Show SMILES C[C@@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N |r| Show InChI InChI=1S/C15H17N5O/c1-15(9-16)6-2-5-12(15)19-13-10(14(17)21)8-18-20-7-3-4-11(13)20/h3-4,7-8,12,19H,2,5-6H2,1H3,(H2,17,21)/t12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035812 (CHEMBL3359919) Show SMILES CC1(C)[C@@H](N)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H21N5O/c1-15(2)11(16)5-6-12(15)19-13-9(14(17)21)8-18-20-7-3-4-10(13)20/h3-4,7-8,11-12,19H,5-6,16H2,1-2H3,(H2,17,21)/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035851 (CHEMBL3359917) Show SMILES C[C@@]1(O)C[C@@H](Nc2c(cnn3cccc23)C(N)=O)C(C)(C)C1 |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)9-16(3,22)7-12(15)19-13-10(14(17)21)8-18-20-6-4-5-11(13)20/h4-6,8,12,19,22H,7,9H2,1-3H3,(H2,17,21)/t12-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035837 (CHEMBL3359926) Show SMILES C[C@@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N |r| Show InChI InChI=1S/C15H17N5O/c1-15(9-16)6-2-5-12(15)19-13-10(14(17)21)8-18-20-7-3-4-11(13)20/h3-4,7-8,12,19H,2,5-6H2,1H3,(H2,17,21)/t12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035846 (CHEMBL3359912) Show SMILES CC1(C)[C@@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(2)11(5-6-12(15)20)18-13-9(14(16)21)8-17-19-7-3-4-10(13)19/h3-4,7-8,11-12,18,20H,5-6H2,1-2H3,(H2,16,21)/t11-,12+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035842 (CHEMBL3359908) Show SMILES CC1(C)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O/c1-15(2)7-3-6-12(15)18-13-10(14(16)20)9-17-19-8-4-5-11(13)19/h4-5,8-9,12,18H,3,6-7H2,1-2H3,(H2,16,20)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50458647 (CHEMBL4212095) Show SMILES Cn1ccc(C(=O)NCCCc2ccc(Cl)c(Cl)c2)c(O)c1=O Show InChI InChI=1S/C16H16Cl2N2O3/c1-20-8-6-11(14(21)16(20)23)15(22)19-7-2-3-10-4-5-12(17)13(18)9-10/h4-6,8-9,21H,2-3,7H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human HL expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate a...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035841 (CHEMBL3359907) Show SMILES C[C@@H](Nc1c(cnn2cccc12)C(N)=O)C(C)(C)C |r| Show InChI InChI=1S/C14H20N4O/c1-9(14(2,3)4)17-12-10(13(15)19)8-16-18-7-5-6-11(12)18/h5-9,17H,1-4H3,(H2,15,19)/t9-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035810 (CHEMBL3359927) Show SMILES C[C@]1(F)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H17FN4O/c1-14(15)6-2-5-11(14)18-12-9(13(16)20)8-17-19-7-3-4-10(12)19/h3-4,7-8,11,18H,2,5-6H2,1H3,(H2,16,20)/t11-,14+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035814 (CHEMBL3359921) Show SMILES C[C@]1(N)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H23N5O/c1-15(2)12(6-7-16(15,3)18)20-13-10(14(17)22)9-19-21-8-4-5-11(13)21/h4-5,8-9,12,20H,6-7,18H2,1-3H3,(H2,17,22)/t12-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458645 (CHEMBL4215063) Show SMILES OC1=C(CN(CCCN2CCCC2=O)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H25Cl2N3O4/c22-16-7-6-14(12-17(16)23)4-1-8-24-20(29)15-13-26(21(30)19(15)28)11-3-10-25-9-2-5-18(25)27/h6-7,12,28H,1-5,8-11,13H2,(H,24,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458642 (CHEMBL4218352) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCOC(C)C)C1=O |t:19| Show InChI InChI=1S/C21H29Cl2N3O3/c1-4-26-13-16(19(21(26)28)24-10-11-29-14(2)3)20(27)25-9-5-6-15-7-8-17(22)18(23)12-15/h7-8,12,14,24H,4-6,9-11,13H2,1-3H3,(H,25,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035847 (CHEMBL3359913) Show SMILES CC1(C)[C@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(2)11(5-6-12(15)20)18-13-9(14(16)21)8-17-19-7-3-4-10(13)19/h3-4,7-8,11-12,18,20H,5-6H2,1-2H3,(H2,16,21)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035847 (CHEMBL3359913) Show SMILES CC1(C)[C@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(2)11(5-6-12(15)20)18-13-9(14(16)21)8-17-19-7-3-4-10(13)19/h3-4,7-8,11-12,18,20H,5-6H2,1-2H3,(H2,16,21)/t11-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035842 (CHEMBL3359908) Show SMILES CC1(C)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O/c1-15(2)7-3-6-12(15)18-13-10(14(16)20)9-17-19-8-4-5-11(13)19/h4-5,8-9,12,18H,3,6-7H2,1-2H3,(H2,16,20)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035817 (CHEMBL3359924) Show SMILES C[C@]1(CO)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(9-20)6-2-5-12(15)18-13-10(14(16)21)8-17-19-7-3-4-11(13)19/h3-4,7-8,12,18,20H,2,5-6,9H2,1H3,(H2,16,21)/t12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035811 (CHEMBL3359918) Show SMILES CC1(C)[C@H](N)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H21N5O/c1-15(2)11(16)5-6-12(15)19-13-9(14(17)21)8-18-20-7-3-4-10(13)20/h3-4,7-8,11-12,19H,5-6,16H2,1-2H3,(H2,17,21)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458636 (CHEMBL4206624) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCCN2CCCCC2)C1=O |t:19| Show InChI InChI=1S/C24H34Cl2N4O2/c1-2-30-17-19(22(24(30)32)27-12-7-15-29-13-4-3-5-14-29)23(31)28-11-6-8-18-9-10-20(25)21(26)16-18/h9-10,16,27H,2-8,11-15,17H2,1H3,(H,28,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035849 (CHEMBL3359915) Show SMILES C[C@@]1(O)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)12(6-7-16(15,3)22)19-13-10(14(17)21)9-18-20-8-4-5-11(13)20/h4-5,8-9,12,19,22H,6-7H2,1-3H3,(H2,17,21)/t12-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035848 (CHEMBL3359914) Show SMILES C[C@]1(O)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)12(6-7-16(15,3)22)19-13-10(14(17)21)9-18-20-8-4-5-11(13)20/h4-5,8-9,12,19,22H,6-7H2,1-3H3,(H2,17,21)/t12-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458644 (CHEMBL4214459) Show SMILES CN1C(CC(C)(C)C)C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:23| Show InChI InChI=1S/C20H26Cl2N2O3/c1-20(2,3)11-15-16(17(25)19(27)24(15)4)18(26)23-9-5-6-12-7-8-13(21)14(22)10-12/h7-8,10,15,25H,5-6,9,11H2,1-4H3,(H,23,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035838 (CHEMBL3352892) Show SMILES C[C@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N |r| Show InChI InChI=1S/C15H17N5O/c1-15(9-16)6-2-5-12(15)19-13-10(14(17)21)8-18-20-7-3-4-11(13)20/h3-4,7-8,12,19H,2,5-6H2,1H3,(H2,17,21)/t12-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035841 (CHEMBL3359907) Show SMILES C[C@@H](Nc1c(cnn2cccc12)C(N)=O)C(C)(C)C |r| Show InChI InChI=1S/C14H20N4O/c1-9(14(2,3)4)17-12-10(13(15)19)8-16-18-7-5-6-11(12)18/h5-9,17H,1-4H3,(H2,15,19)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458646 (CHEMBL4207746) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:19| Show InChI InChI=1S/C16H18Cl2N2O3/c1-2-20-9-11(14(21)16(20)23)15(22)19-7-3-4-10-5-6-12(17)13(18)8-10/h5-6,8,21H,2-4,7,9H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035850 (CHEMBL3359916) Show SMILES C[C@]1(O)C[C@@H](Nc2c(cnn3cccc23)C(N)=O)C(C)(C)C1 |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)9-16(3,22)7-12(15)19-13-10(14(17)21)8-18-20-6-4-5-11(13)20/h4-6,8,12,19,22H,7,9H2,1-3H3,(H2,17,21)/t12-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035849 (CHEMBL3359915) Show SMILES C[C@@]1(O)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H22N4O2/c1-15(2)12(6-7-16(15,3)22)19-13-10(14(17)21)9-18-20-8-4-5-11(13)20/h4-5,8-9,12,19,22H,6-7H2,1-3H3,(H2,17,21)/t12-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035837 (CHEMBL3359926) Show SMILES C[C@@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N |r| Show InChI InChI=1S/C15H17N5O/c1-15(9-16)6-2-5-12(15)19-13-10(14(17)21)8-18-20-7-3-4-11(13)20/h3-4,7-8,12,19H,2,5-6H2,1H3,(H2,17,21)/t12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035813 (CHEMBL3359920) Show SMILES C[C@@]1(N)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C |r| Show InChI InChI=1S/C16H23N5O/c1-15(2)12(6-7-16(15,3)18)20-13-10(14(17)22)9-19-21-8-4-5-11(13)21/h4-5,8-9,12,20H,6-7,18H2,1-3H3,(H2,17,22)/t12-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035812 (CHEMBL3359919) Show SMILES CC1(C)[C@@H](N)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H21N5O/c1-15(2)11(16)5-6-12(15)19-13-9(14(17)21)8-18-20-7-3-4-10(13)20/h3-4,7-8,11-12,19H,5-6,16H2,1-2H3,(H2,17,21)/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50035817 (CHEMBL3359924) Show SMILES C[C@]1(CO)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(9-20)6-2-5-12(15)18-13-10(14(16)21)8-17-19-7-3-4-11(13)19/h3-4,7-8,12,18,20H,2,5-6,9H2,1H3,(H2,16,21)/t12-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of TYK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50035811 (CHEMBL3359918) Show SMILES CC1(C)[C@H](N)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H21N5O/c1-15(2)11(16)5-6-12(15)19-13-9(14(17)21)8-18-20-7-3-4-10(13)20/h3-4,7-8,11-12,19H,5-6,16H2,1-2H3,(H2,17,21)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) bycaliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458639 (CHEMBL4207216) Show SMILES CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:18| Show InChI InChI=1S/C15H16Cl2N2O3/c1-19-8-10(13(20)15(19)22)14(21)18-6-2-3-9-4-5-11(16)12(17)7-9/h4-5,7,20H,2-3,6,8H2,1H3,(H,18,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035816 (CHEMBL3359923) Show SMILES C[C@@]1(O)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H18N4O2/c1-14(20)6-2-5-11(14)17-12-9(13(15)19)8-16-18-7-3-4-10(12)18/h3-4,7-8,11,17,20H,2,5-6H2,1H3,(H2,15,19)/t11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50035847 (CHEMBL3359913) Show SMILES CC1(C)[C@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C15H20N4O2/c1-15(2)11(5-6-12(15)20)18-13-9(14(16)21)8-17-19-7-3-4-10(13)19/h3-4,7-8,11-12,18,20H,5-6H2,1-2H3,(H2,16,21)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by caliper assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50035840 (CHEMBL3359929) Show SMILES C[C@@]1(F)CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O |r| Show InChI InChI=1S/C14H17FN4O/c1-14(15)6-2-5-11(14)18-12-9(13(16)20)8-17-19-7-3-4-10(12)19/h3-4,7-8,11,18H,2,5-6H2,1H3,(H2,16,20)/t11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by filter assay				Bioorg Med Chem Lett 24: 5721-6 (2014) Article DOI: 10.1016/j.bmcl.2014.10.061 BindingDB Entry DOI: 10.7270/Q2D79D1K
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458640 (CHEMBL4203934) Show SMILES CCN1CC(C(=O)NC(C)CCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:20| Show InChI InChI=1S/C17H20Cl2N2O3/c1-3-21-9-12(15(22)17(21)24)16(23)20-10(2)4-5-11-6-7-13(18)14(19)8-11/h6-8,10,22H,3-5,9H2,1-2H3,(H,20,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair

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