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Compile Data Set for Download or QSAR

Found 11 hits with Last Name = 'hollis' and Initial = 'jm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))
BDBM85530
PNG
(Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...)
Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1
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27n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM85530
PNG
(Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...)
Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1
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56n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))
BDBM85598
PNG
(l-norfenfluramine)
Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1
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65n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM85598
PNG
(l-norfenfluramine)
Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1
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99n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM85530
PNG
(Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...)
Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1
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187n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM85598
PNG
(l-norfenfluramine)
Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1
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267n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))
BDBM85597
PNG
(CAS_37577-24-5 | NSC_65801 | l-Fenfluramine)
Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1
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680n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM85597
PNG
(CAS_37577-24-5 | NSC_65801 | l-Fenfluramine)
Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1
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1.43E+3n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM85597
PNG
(CAS_37577-24-5 | NSC_65801 | l-Fenfluramine)
Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1
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PubMed
1.62E+3n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM85596
PNG
(CAS_3239-45-0 | NSC_65801 | d-Fenfluramine)
Show SMILES CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
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PubMed
2.08E+3n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))
BDBM85596
PNG
(CAS_3239-45-0 | NSC_65801 | d-Fenfluramine)
Show SMILES CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
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PubMed
3.92E+3n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Research Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 57: 75-81 (2000)


BindingDB Entry DOI: 10.7270/Q2P26WPH
More data for this
Ligand-Target Pair