Found 15 hits with Last Name = 'humerickhouse' and Initial = 'ra' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044989
((O10eq)-beta-guanidinopropionylryanodine | CHEMBL2...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCNC(N)=N)C(C)CCC35O)C2(O)C14C |TLB:37:16:41:22.21,15:14:22.37:41.19.18,15:14:41:22.21,40:39:3.5:16.19.18,3:41:22.21:14.16.18,20:19:39:3.5,6:5:39:16.19.18,THB:22:39:3.5:16.19.18,42:41:22.21:14.16.18,37:22:41:14.16.18,37:16:39:3.5,5:14:22.37:41.19.18,5:14:41:22.21,21:19:39:3.5,23:22:41:14.16.18,4:3:39:16.19.18| Show InChI InChI=1S/C29H42N4O10/c1-14(2)26(38)20(42-19(35)16-7-6-11-32-16)27(39)22(4)13-25(37)23(26,5)29(27,40)28(43-25)18(15(3)8-10-24(22,28)36)41-17(34)9-12-33-21(30)31/h6-7,11,14-15,18,20,32,36-40H,8-10,12-13H2,1-5H3,(H4,30,31,33)/t15?,18-,20-,22+,23?,24?,25?,26?,27?,28?,29?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044982
(CHEMBL283836 | GLYCYLRYANODINE)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CN)C(C)CCC35O)C2(O)C14C |TLB:15:14:22.33:37.19.18,15:14:37:22.21,36:35:3.5:16.19.18,33:16:37:22.21,3:37:22.21:14.16.18,20:19:35:3.5,6:5:35:16.19.18,THB:22:35:3.5:16.19.18,33:22:37:14.16.18,33:16:35:3.5,5:14:22.33:37.19.18,5:14:37:22.21,21:19:35:3.5,23:22:37:14.16.18,4:3:35:16.19.18,38:37:22.21:14.16.18| Show InChI InChI=1S/C27H38N2O10/c1-13(2)24(34)19(38-18(31)15-7-6-10-29-15)25(35)20(4)12-23(33)21(24,5)27(25,36)26(39-23)17(37-16(30)11-28)14(3)8-9-22(20,26)32/h6-7,10,13-14,17,19,29,32-36H,8-9,11-12,28H2,1-5H3/t14?,17-,19-,20+,21?,22?,23?,24?,25?,26?,27?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044986
((O10eq)-guanidino acetylryanodine | CHEMBL435362)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CNC(N)=N)C(C)CCC35O)C2(O)C14C |TLB:36:16:40:22.21,39:38:3.5:16.19.18,3:40:22.21:14.16.18,15:14:22.36:40.19.18,15:14:40:22.21,6:5:38:16.19.18,20:19:38:3.5,THB:22:38:3.5:16.19.18,41:40:22.21:14.16.18,36:22:40:14.16.18,36:16:38:3.5,5:14:22.36:40.19.18,5:14:40:22.21,21:19:38:3.5,23:22:40:14.16.18,4:3:38:16.19.18| Show InChI InChI=1S/C28H40N4O10/c1-13(2)25(37)19(41-18(34)15-7-6-10-31-15)26(38)21(4)12-24(36)22(25,5)28(26,39)27(42-24)17(14(3)8-9-23(21,27)35)40-16(33)11-32-20(29)30/h6-7,10,13-14,17,19,31,35-39H,8-9,11-12H2,1-5H3,(H4,29,30,32)/t14?,17-,19-,21+,22?,23?,24?,25?,26?,27?,28?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044995
((O10eq)-beta-alanylryanodine | CHEMBL282089)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCN)C(C)CCC35O)C2(O)C14C |TLB:15:14:22.34:38.19.18,15:14:38:22.21,37:36:3.5:16.19.18,34:16:38:22.21,3:38:22.21:14.16.18,20:19:36:3.5,6:5:36:16.19.18,THB:22:36:3.5:16.19.18,34:22:38:14.16.18,34:16:36:3.5,5:14:22.34:38.19.18,5:14:38:22.21,21:19:36:3.5,23:22:38:14.16.18,4:3:36:16.19.18,39:38:22.21:14.16.18| Show InChI InChI=1S/C28H40N2O10/c1-14(2)25(35)20(39-19(32)16-7-6-12-30-16)26(36)21(4)13-24(34)22(25,5)28(26,37)27(40-24)18(38-17(31)9-11-29)15(3)8-10-23(21,27)33/h6-7,12,14-15,18,20,30,33-37H,8-11,13,29H2,1-5H3/t15?,18-,20-,21+,22?,23?,24?,25?,26?,27?,28?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044993
(Benzyloxycarbonyl-glycylryanodine | CHEMBL28383)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CNC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C |TLB:43:16:47:22.21,15:14:22.43:47.19.18,15:14:47:22.21,46:45:3.5:16.19.18,3:47:22.21:14.16.18,20:19:45:3.5,6:5:45:16.19.18,THB:22:45:3.5:16.19.18,48:47:22.21:14.16.18,43:22:47:14.16.18,43:16:45:3.5,5:14:22.43:47.19.18,5:14:47:22.21,21:19:45:3.5,23:22:47:14.16.18,4:3:45:16.19.18| Show InChI InChI=1S/C35H44N2O12/c1-19(2)32(43)26(48-25(39)22-12-9-15-36-22)33(44)28(4)18-31(42)29(32,5)35(33,45)34(49-31)24(20(3)13-14-30(28,34)41)47-23(38)16-37-27(40)46-17-21-10-7-6-8-11-21/h6-12,15,19-20,24,26,36,41-45H,13-14,16-18H2,1-5H3,(H,37,40)/t20?,24-,26-,28+,29?,30?,31?,32?,33?,34?,35?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044990
((O10eq)-Benzyloxycarbonyl-beta-alanylryanodine | C...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCNC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C |TLB:47:46:3.5:16.19.18,44:16:48:22.21,3:48:22.21:14.16.18,15:14:22.44:48.19.18,15:14:48:22.21,20:19:46:3.5,6:5:46:16.19.18,THB:22:46:3.5:16.19.18,49:48:22.21:14.16.18,44:22:48:14.16.18,44:16:46:3.5,5:14:22.44:48.19.18,5:14:48:22.21,21:19:46:3.5,23:22:48:14.16.18,4:3:46:16.19.18| Show InChI InChI=1S/C36H46N2O12/c1-20(2)33(44)27(49-26(40)23-12-9-16-37-23)34(45)29(4)19-32(43)30(33,5)36(34,46)35(50-32)25(21(3)13-15-31(29,35)42)48-24(39)14-17-38-28(41)47-18-22-10-7-6-8-11-22/h6-12,16,20-21,25,27,37,42-46H,13-15,17-19H2,1-5H3,(H,38,41)/t21?,25-,27-,29+,30?,31?,32?,33?,34?,35?,36?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044994
(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)Show SMILES CC(C)[C@@]1(O)[C@@H](OC(=O)c2cc[nH]c2)[C@@]2(O)[C@]3(C)C[C@@]4(O)O[C@@]5([C@H](O)[C@@H](C)CC[C@]35O)[C@@]2(O)[C@]14C |r,TLB:28:29:31.33:21,34:33:21:29.16.18,THB:14:16:31.33:21,14:31:21:29.16.18,3:33:21:29.16.18,33:19:29:31.14,32:31:21:29.16.18| Show InChI InChI=1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-9-26-10-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)6-8-20(18,24)29/h7,9-10,12-13,15,17,26-27,29-33H,6,8,11H2,1-5H3/t13-,15+,17+,18+,19-,20-,21+,22+,23+,24+,25+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044991
(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](O)C(=C)CCC35O)C2(O)C14C |TLB:33:31:29:19.21.18,5:14:29:19.21.18,20:19:31.14:29,28:29:31.14:19.21.18,THB:15:14:29:19.21.18,33:19:31.14:29,32:31:29:19.21.18,30:29:31.14:19.21.18| Show InChI InChI=1S/C25H33NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12,15,17,26-27,29-33H,3,8-9,11H2,1-2,4-5H3/t15-,17-,18+,19?,20?,21?,22?,23?,24?,25?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044987
((O10eq)-beta-N,N'-Bis-Benzyloxycarbonyl-guanidinop...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCNC(NC(=O)OCc6ccccc6)=NC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C |w:42.44,TLB:57:16:61:22.21,3:61:22.21:14.16.18,60:59:3.5:16.19.18,15:14:22.57:61.19.18,15:14:61:22.21,6:5:59:16.19.18,20:19:59:3.5,THB:22:59:3.5:16.19.18,57:22:61:14.16.18,57:16:59:3.5,4:3:59:16.19.18,5:14:22.57:61.19.18,5:14:61:22.21,21:19:59:3.5,23:22:61:14.16.18,62:61:22.21:14.16.18| Show InChI InChI=1S/C45H54N4O14/c1-26(2)42(56)34(62-33(51)30-17-12-21-46-30)43(57)38(4)25-41(55)39(42,5)45(43,58)44(63-41)32(27(3)18-20-40(38,44)54)61-31(50)19-22-47-35(48-36(52)59-23-28-13-8-6-9-14-28)49-37(53)60-24-29-15-10-7-11-16-29/h6-17,21,26-27,32,34,46,54-58H,18-20,22-25H2,1-5H3,(H2,47,48,49,52,53)/t27?,32-,34-,38+,39?,40?,41?,42?,43?,44?,45?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044988
(CHEMBL432278 | N-methyl ryanodine-succinamidate)Show SMILES CNC(=O)CCC(=O)O[C@@H]1C(C)CCC2(O)[C@]3(C)CC4(O)OC12C1(O)C3(O)[C@H](OC(=O)c2ccc[nH]2)C(O)(C(C)C)C41C |TLB:22:23:36.27:16.19.18,14:16:41:22.21,14:16:23:36.27,26:25:22.14:41.19.18,26:25:41:22.21,21:19:23:36.27,28:27:23:16.19.18,42:41:22.21:25.16.18,THB:24:23:36.27:16.19.18,14:22:41:25.16.18,36:41:22.21:25.16.18,27:25:22.14:41.19.18,27:25:41:22.21,9:22:41:25.16.18,20:19:23:36.27,37:36:23:16.19.18| Show InChI InChI=1S/C30H42N2O11/c1-15(2)27(38)22(42-21(35)17-8-7-13-32-17)28(39)23(4)14-26(37)24(27,5)30(28,40)29(43-26)20(16(3)11-12-25(23,29)36)41-19(34)10-9-18(33)31-6/h7-8,13,15-16,20,22,32,36-40H,9-12,14H2,1-6H3,(H,31,33)/t16?,20-,22-,23+,24?,25?,26?,27?,28?,29?,30?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044984
(CHEMBL416926 | Di-Benzyloxycarbonyl-guanidino acet...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CNC(NC(=O)OCc6ccccc6)=NC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C |w:41.43,TLB:56:16:60:22.21,3:60:22.21:14.16.18,15:14:22.56:60.19.18,15:14:60:22.21,59:58:3.5:16.19.18,6:5:58:16.19.18,20:19:58:3.5,THB:22:58:3.5:16.19.18,56:22:60:14.16.18,56:16:58:3.5,4:3:58:16.19.18,5:14:22.56:60.19.18,5:14:60:22.21,21:19:58:3.5,61:60:22.21:14.16.18,23:22:60:14.16.18| Show InChI InChI=1S/C44H52N4O14/c1-25(2)41(55)33(61-32(50)29-17-12-20-45-29)42(56)37(4)24-40(54)38(41,5)44(42,57)43(62-40)31(26(3)18-19-39(37,43)53)60-30(49)21-46-34(47-35(51)58-22-27-13-8-6-9-14-27)48-36(52)59-23-28-15-10-7-11-16-28/h6-17,20,25-26,31,33,45,53-57H,18-19,21-24H2,1-5H3,(H2,46,47,48,51,52)/t26?,31-,33-,37+,38?,39?,40?,41?,42?,43?,44?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044992
((O10eq)-beta-alanyl-anhydro-ryanodine | CHEMBL2826...)Show SMILES CC(C)C1=C(C)C2(O)C(O)([C@@H]1OC(=O)c1ccc[nH]1)[C@@]1(C)CC(=O)OC22[C@H](OC(=O)CCN)C(C)CCC12O |wU:19.21,wD:10.11,26.29,c:3,TLB:4:6:37:24.22.21,10:8:37:24.22.21,38:37:6.8:24.22.21,THB:9:8:37:24.22.21,7:6:37:24.22.21,36:37:6.8:24.22.21,(4.84,-6.94,;5.24,-5.46,;4.15,-4.37,;6.73,-5.07,;8.7,-5.01,;7.91,-3.67,;9.98,-4.14,;10.15,-2.63,;10.09,-5.53,;9.22,-3.56,;8.23,-6.17,;8.22,-7.7,;7.45,-9.03,;8.21,-10.35,;5.91,-9.01,;5.01,-7.77,;3.54,-8.24,;3.53,-9.77,;4.98,-10.26,;11.98,-6.31,;13.08,-7.39,;12.12,-8.19,;9.93,-8.89,;9.35,-10.29,;10.49,-6.7,;11.52,-4.98,;12.73,-4,;11.4,-3.23,;11.42,-.94,;12.75,-.17,;10.1,-.17,;10.1,1.36,;8.77,2.14,;14,-4.87,;15.08,-3.77,;15.42,-4.74,;14.31,-5.89,;12.77,-4.91,;14.15,-3.33,)| Show InChI InChI=1S/C28H38N2O9/c1-14(2)20-16(4)26(35)27(36,22(20)38-23(33)17-7-6-12-30-17)24(5)13-19(32)39-28(26)21(37-18(31)9-11-29)15(3)8-10-25(24,28)34/h6-7,12,14-15,21-22,30,34-36H,8-11,13,29H2,1-5H3/t15?,21-,22-,24+,25?,26?,27?,28?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044985
(ryanodine-hemi-succinate)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCC([O-])=O)C(C)CCC35O)C2(O)C14C |TLB:39:38:3.5:16.19.18,36:16:40:22.21,3:40:22.21:14.16.18,15:14:22.36:40.19.18,15:14:40:22.21,20:19:38:3.5,6:5:38:16.19.18,THB:22:38:3.5:16.19.18,41:40:22.21:14.16.18,36:22:40:14.16.18,36:16:38:3.5,5:14:22.36:40.19.18,5:14:40:22.21,21:19:38:3.5,23:22:40:14.16.18,4:3:38:16.19.18| Show InChI InChI=1S/C29H39NO12/c1-14(2)26(37)21(41-20(34)16-7-6-12-30-16)27(38)22(4)13-25(36)23(26,5)29(27,39)28(42-25)19(15(3)10-11-24(22,28)35)40-18(33)9-8-17(31)32/h6-7,12,14-15,19,21,30,35-39H,8-11,13H2,1-5H3,(H,31,32)/p-1/t15?,19-,21-,22+,23?,24?,25?,26?,27?,28?,29?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044991
(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](O)C(=C)CCC35O)C2(O)C14C |TLB:33:31:29:19.21.18,5:14:29:19.21.18,20:19:31.14:29,28:29:31.14:19.21.18,THB:15:14:29:19.21.18,33:19:31.14:29,32:31:29:19.21.18,30:29:31.14:19.21.18| Show InChI InChI=1S/C25H33NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12,15,17,26-27,29-33H,3,8-9,11H2,1-2,4-5H3/t15-,17-,18+,19?,20?,21?,22?,23?,24?,25?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
Ryanodine receptor 1
(Oryctolagus cuniculus) | BDBM50044991
(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](O)C(=C)CCC35O)C2(O)C14C |TLB:33:31:29:19.21.18,5:14:29:19.21.18,20:19:31.14:29,28:29:31.14:19.21.18,THB:15:14:29:19.21.18,33:19:31.14:29,32:31:29:19.21.18,30:29:31.14:19.21.18| Show InChI InChI=1S/C25H33NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12,15,17,26-27,29-33H,3,8-9,11H2,1-2,4-5H3/t15-,17-,18+,19?,20?,21?,22?,23?,24?,25?/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University
Curated by ChEMBL
| Assay Description
Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles |
J Med Chem 36: 1319-23 (1993)
BindingDB Entry DOI: 10.7270/Q2PN968V |
More data for this
Ligand-Target Pair | |
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