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Compile Data Set for Download or QSAR

Found 18 hits with Last Name = 'kammasud' and Initial = 'n'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50256010
PNG
(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(=O)NNc2ccccc2)c(C)c1CCC(O)=O
Show InChI InChI=1S/C25H24N4O4/c1-14-18(9-11-23(30)31)15(2)26-22(14)13-20-19-12-16(8-10-21(19)27-25(20)33)24(32)29-28-17-6-4-3-5-7-17/h3-8,10,12-13,26,28H,9,11H2,1-2H3,(H,27,33)(H,29,32)(H,30,31)/b20-13-
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n/an/a 40n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM4811
PNG
((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Show InChI InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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n/an/a 50n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50256010
PNG
(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(=O)NNc2ccccc2)c(C)c1CCC(O)=O
Show InChI InChI=1S/C25H24N4O4/c1-14-18(9-11-23(30)31)15(2)26-22(14)13-20-19-12-16(8-10-21(19)27-25(20)33)24(32)29-28-17-6-4-3-5-7-17/h3-8,10,12-13,26,28H,9,11H2,1-2H3,(H,27,33)(H,29,32)(H,30,31)/b20-13-
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n/an/a 70n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50256010
PNG
(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(=O)NNc2ccccc2)c(C)c1CCC(O)=O
Show InChI InChI=1S/C25H24N4O4/c1-14-18(9-11-23(30)31)15(2)26-22(14)13-20-19-12-16(8-10-21(19)27-25(20)33)24(32)29-28-17-6-4-3-5-7-17/h3-8,10,12-13,26,28H,9,11H2,1-2H3,(H,27,33)(H,29,32)(H,30,31)/b20-13-
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n/an/a 100n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 expressed in insect cells by HTRF method


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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n/an/a 400n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 kinase expressed in insect cell by HTRF detection method


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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n/an/a 520n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 expressed in insect cells by HTRF method


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM4811
PNG
((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Show InChI InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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n/an/a 680n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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n/an/a 780n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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n/an/a 930n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4901
PNG
(3-(5-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Show SMILES COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C25H24N2O4/c1-14-19(9-10-24(28)29)15(2)26-22(14)13-21-20-8-7-17(12-23(20)27-25(21)30)16-5-4-6-18(11-16)31-3/h4-8,11-13,26H,9-10H2,1-3H3,(H,27,30)(H,28,29)/b21-13-
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n/an/a 1.20E+3n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 kinase expressed in insect cell by HTRF detection method


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4811
PNG
((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Show InChI InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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n/an/a 1.81E+3n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 expressed in insect cells by HTRF method


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50256010
PNG
(3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(=O)NNc2ccccc2)c(C)c1CCC(O)=O
Show InChI InChI=1S/C25H24N4O4/c1-14-18(9-11-23(30)31)15(2)26-22(14)13-20-19-12-16(8-10-21(19)27-25(20)33)24(32)29-28-17-6-4-3-5-7-17/h3-8,10,12-13,26,28H,9,11H2,1-2H3,(H,27,33)(H,29,32)(H,30,31)/b20-13-
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n/an/a 3.48E+3n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4901
PNG
(3-(5-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Show SMILES COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C25H24N2O4/c1-14-19(9-10-24(28)29)15(2)26-22(14)13-21-20-8-7-17(12-23(20)27-25(21)30)16-5-4-6-18(11-16)31-3/h4-8,11-13,26H,9-10H2,1-3H3,(H,27,30)(H,28,29)/b21-13-
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n/an/a 1.79E+4n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of rhFGF2-induced cellular proliferation of HUVEC


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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n/an/a 1.82E+4n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of rhFGF2-induced cellular proliferation of HUVEC


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4900
PNG
(3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydr...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(ccc23)-c2ccccc2)c(C)c1CCC(O)=O
Show InChI InChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,28)/b20-13-
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n/an/a>5.00E+4n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of rhFGF2-induced cellular proliferation of HUVEC


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM4811
PNG
((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Show InChI InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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n/an/a>5.00E+4n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of rhFGF2-induced cellular proliferation of HUVEC


Bioorg Med Chem Lett 17: 4812-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.058
BindingDB Entry DOI: 10.7270/Q29886Q3
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM4811
PNG
((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Show InChI InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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n/an/a>1.00E+5n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50217602
PNG
((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Show SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C26H26N2O5/c1-14-20(7-8-25(29)30)15(2)27-23(14)13-22-21-6-5-16(11-24(21)28-26(22)31)17-9-18(32-3)12-19(10-17)33-4/h5-6,9-13,27H,7-8H2,1-4H3,(H,28,31)(H,29,30)/b22-13-
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Mahidol University

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin)


Bioorg Med Chem Lett 19: 745-50 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.023
BindingDB Entry DOI: 10.7270/Q2028RDT
More data for this
Ligand-Target Pair