Compile Data Set for Download or QSAR

Found 90 hits with Last Name = 'karthikeyan' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50276903 (CHEMBL4171764) Show SMILES Brc1cccc(Nc2ncnc3sc4CCCCc4c23)c1 Show InChI InChI=1S/C16H14BrN3S/c17-10-4-3-5-11(8-10)20-15-14-12-6-1-2-7-13(12)21-16(14)19-9-18-15/h3-5,8-9H,1-2,6-7H2,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Inhibition of EGFR1 (unknown origin) after 1 hr in presence of adenosine 5'[gamma-33P]triphosphate by microbeta microplate counting method				Eur J Med Chem 138: 1053-1065 (2017) Article DOI: 10.1016/j.ejmech.2017.07.028 BindingDB Entry DOI: 10.7270/Q2794760
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2939 (4-(2-cyclopropylethynyl)-5-fluoro-4-(trifluorometh...) Show SMILES Fc1cccc2NC(=O)OC(C#CC3CC3)(c12)C(F)(F)F Show InChI InChI=1S/C14H9F4NO2/c15-9-2-1-3-10-11(9)13(14(16,17)18,21-12(20)19-10)7-6-8-4-5-8/h1-3,8H,4-5H2,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM7401 ((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...) Show SMILES Brc1ccc2C(C(=O)Nc2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,13,18H,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2942 (5-fluoro-4-(3-methylbut-1-yn-1-yl)-4-(trifluoromet...) Show SMILES CC(C)C#CC1(OC(=O)Nc2cccc(F)c12)C(F)(F)F Show InChI InChI=1S/C14H11F4NO2/c1-8(2)6-7-13(14(16,17)18)11-9(15)4-3-5-10(11)19-12(20)21-13/h3-5,8H,1-2H3,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2940 (4-(but-1-yn-1-yl)-5-fluoro-4-(trifluoromethyl)-2,4...) Show SMILES CCC#CC1(OC(=O)Nc2cccc(F)c12)C(F)(F)F Show InChI InChI=1S/C13H9F4NO2/c1-2-3-7-12(13(15,16)17)10-8(14)5-4-6-9(10)18-11(19)20-12/h4-6H,2H2,1H3,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2941 (5-fluoro-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,...) Show SMILES CCCC#CC1(OC(=O)Nc2cccc(F)c12)C(F)(F)F Show InChI InChI=1S/C14H11F4NO2/c1-2-3-4-8-13(14(16,17)18)11-9(15)6-5-7-10(11)19-12(20)21-13/h5-7H,2-3H2,1H3,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2946 (4-(3-methylbut-1-yn-1-yl)-6-nitro-4-(trifluorometh...) Show SMILES CC(C)C#CC1(OC(=O)Nc2ccc(cc12)[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O4/c1-8(2)5-6-13(14(15,16)17)10-7-9(19(21)22)3-4-11(10)18-12(20)23-13/h3-4,7-8H,1-2H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2943 (4-(2-cyclopropylethynyl)-6-nitro-4-(trifluoromethy...) Show SMILES [O-][N+](=O)c1ccc2NC(=O)OC(C#CC3CC3)(c2c1)C(F)(F)F Show InChI InChI=1S/C14H9F3N2O4/c15-14(16,17)13(6-5-8-1-2-8)10-7-9(19(21)22)3-4-11(10)18-12(20)23-13/h3-4,7-8H,1-2H2,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2944 (4-(but-1-yn-1-yl)-6-nitro-4-(trifluoromethyl)-2,4-...) Show SMILES CCC#CC1(OC(=O)Nc2ccc(cc12)[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C13H9F3N2O4/c1-2-3-6-12(13(14,15)16)9-7-8(18(20)21)4-5-10(9)17-11(19)22-12/h4-5,7H,2H2,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	276	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2945 (6-nitro-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,4...) Show SMILES CCCC#CC1(OC(=O)Nc2ccc(cc12)[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O4/c1-2-3-4-7-13(14(15,16)17)10-8-9(19(21)22)5-6-11(10)18-12(20)23-13/h5-6,8H,2-3H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2952 (6-(methylamino)-4-(3-methylbut-1-yn-1-yl)-4-(trifl...) Show SMILES CNc1ccc2NC(=O)OC(C#CC(C)C)(c2c1)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O2/c1-9(2)6-7-14(15(16,17)18)11-8-10(19-3)4-5-12(11)20-13(21)22-14/h4-5,8-9,19H,1-3H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	473	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM7401 ((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...) Show SMILES Brc1ccc2C(C(=O)Nc2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,13,18H,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2951 (4-(2-cyclopropylethynyl)-6-(methylamino)-4-(triflu...) Show SMILES CNc1ccc2NC(=O)OC(C#CC3CC3)(c2c1)C(F)(F)F Show InChI InChI=1S/C15H13F3N2O2/c1-19-10-4-5-12-11(8-10)14(15(16,17)18,22-13(21)20-12)7-6-9-2-3-9/h4-5,8-9,19H,2-3H2,1H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	608	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2947 (6-amino-4-(2-cyclopropylethynyl)-4-(trifluoromethy...) Show SMILES Nc1ccc2NC(=O)OC(C#CC3CC3)(c2c1)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O2/c15-14(16,17)13(6-5-8-1-2-8)10-7-9(18)3-4-11(10)19-12(20)21-13/h3-4,7-8H,1-2,18H2,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	802	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2950 (6-amino-4-(3-methylbut-1-yn-1-yl)-4-(trifluorometh...) Show SMILES CC(C)C#CC1(OC(=O)Nc2ccc(N)cc12)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O2/c1-8(2)5-6-13(14(15,16)17)10-7-9(18)3-4-11(10)19-12(20)21-13/h3-4,7-8H,18H2,1-2H3,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	896	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50290835 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C18H19N3O4/c1-22-14-6-5-11(7-15(14)23-2)21-18-12-8-16(24-3)17(25-4)9-13(12)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2949 (6-amino-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,4...) Show SMILES CCCC#CC1(OC(=O)Nc2ccc(N)cc12)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O2/c1-2-3-4-7-13(14(15,16)17)10-8-9(18)5-6-11(10)19-12(20)21-13/h5-6,8H,2-3,18H2,1H3,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2948 (6-amino-4-(but-1-yn-1-yl)-4-(trifluoromethyl)-2,4-...) Show SMILES CCC#CC1(OC(=O)Nc2ccc(N)cc12)C(F)(F)F Show InChI InChI=1S/C13H11F3N2O2/c1-2-3-6-12(13(14,15)16)9-7-8(17)4-5-10(9)18-11(19)20-12/h4-5,7H,2,17H2,1H3,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2954 (Benzoxazinone deriv. 8b | CHEMBL111598 | N-[4-(3-m...) Show SMILES CC(C)C#CC1(OC(=O)Nc2ccc(NC(C)=O)cc12)C(F)(F)F Show InChI InChI=1S/C16H15F3N2O3/c1-9(2)6-7-15(16(17,18)19)12-8-11(20-10(3)22)4-5-13(12)21-14(23)24-15/h4-5,8-9H,1-3H3,(H,20,22)(H,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2953 (Benzoxazinone deriv. 8a | CHEMBL111492 | N-[4-(2-c...) Show SMILES CC(=O)Nc1ccc2NC(=O)OC(C#CC3CC3)(c2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O3/c1-9(22)20-11-4-5-13-12(8-11)15(16(17,18)19,24-14(23)21-13)7-6-10-2-3-10/h4-5,8,10H,2-3H2,1H3,(H,20,22)(H,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
S.G.S.I.T.S. Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 6089-94 (2004) Article DOI: 10.1016/j.bmcl.2004.09.068 BindingDB Entry DOI: 10.7270/Q2XS5TVZ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM7401 ((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...) Show SMILES Brc1ccc2C(C(=O)Nc2c1)c1[nH]c2ccccc2c1N=O Show InChI InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,13,18H,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM4626 (Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC Show InChI InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-9-3-4-12(18)11(17)5-9/h3-8H,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50443464 (CHEMBL259888) Show SMILES COc1ccc2nc(SCC(=O)Nc3cc(ccc3C)C(O)=O)[nH]c2c1 Show InChI InChI=1S/C18H17N3O4S/c1-10-3-4-11(17(23)24)7-14(10)19-16(22)9-26-18-20-13-6-5-12(25-2)8-15(13)21-18/h3-8H,9H2,1-2H3,(H,19,22)(H,20,21)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B by malachite green assay				Eur J Med Chem 70: 469-76 (2013) Article DOI: 10.1016/j.ejmech.2013.10.030 BindingDB Entry DOI: 10.7270/Q20R9QWZ
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50443463 (CHEMBL406596) Show SMILES Cc1ccc(cc1NC(=O)CSc1nc2ccccc2s1)C(O)=O Show InChI InChI=1S/C17H14N2O3S2/c1-10-6-7-11(16(21)22)8-13(10)18-15(20)9-23-17-19-12-4-2-3-5-14(12)24-17/h2-8H,9H2,1H3,(H,18,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B by malachite green assay				Eur J Med Chem 70: 469-76 (2013) Article DOI: 10.1016/j.ejmech.2013.10.030 BindingDB Entry DOI: 10.7270/Q20R9QWZ
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50443461 (CHEMBL3087456) Show SMILES Cc1ccc(cc1)-c1nnc(SCC(=O)Nc2cc(ccc2C)C(O)=O)o1 Show InChI InChI=1S/C19H17N3O4S/c1-11-3-6-13(7-4-11)17-21-22-19(26-17)27-10-16(23)20-15-9-14(18(24)25)8-5-12(15)2/h3-9H,10H2,1-2H3,(H,20,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B by malachite green assay				Eur J Med Chem 70: 469-76 (2013) Article DOI: 10.1016/j.ejmech.2013.10.030 BindingDB Entry DOI: 10.7270/Q20R9QWZ
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50443460 (CHEMBL3087457) Show SMILES COc1cc(cc(OC)c1OC)-c1nnc(SCC(=O)Nc2cc(ccc2C)C(O)=O)o1 Show InChI InChI=1S/C21H21N3O7S/c1-11-5-6-12(20(26)27)7-14(11)22-17(25)10-32-21-24-23-19(31-21)13-8-15(28-2)18(30-4)16(9-13)29-3/h5-9H,10H2,1-4H3,(H,22,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B by malachite green assay				Eur J Med Chem 70: 469-76 (2013) Article DOI: 10.1016/j.ejmech.2013.10.030 BindingDB Entry DOI: 10.7270/Q20R9QWZ
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50449207 (CHEMBL3127768) Show SMILES COc1cc2ncnc(Nc3ccc(C)c(C)c3)c2cc1OC Show InChI InChI=1S/C18H19N3O2/c1-11-5-6-13(7-12(11)2)21-18-14-8-16(22-3)17(23-4)9-15(14)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-4-10(6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM3530 (6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...) Show SMILES COc1cc2ncnc(Nc3ccccc3)c2cc1OC Show InChI InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50449204 (CHEMBL1719330) Show SMILES COc1cc2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2cc1OC Show InChI InChI=1S/C17H14F3N3O3/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-10-3-5-11(6-4-10)26-17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50449205 (CHEMBL1277433) Show SMILES COc1cc2ncnc(Nc3ccc(cc3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-10(4-6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50340921 (CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES COc1cc2ncnc(Nc3ccc(NC(C)=O)cc3)c2cc1OC Show InChI InChI=1S/C18H18N4O3/c1-11(23)21-12-4-6-13(7-5-12)22-18-14-8-16(24-2)17(25-3)9-15(14)19-10-20-18/h4-10H,1-3H3,(H,21,23)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50291090 ((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C17H17N3O3/c1-21-12-6-4-11(5-7-12)20-17-13-8-15(22-2)16(23-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50449207 (CHEMBL3127768) Show SMILES COc1cc2ncnc(Nc3ccc(C)c(C)c3)c2cc1OC Show InChI InChI=1S/C18H19N3O2/c1-11-5-6-13(7-12(11)2)21-18-14-8-16(22-3)17(23-4)9-15(14)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-4-10(6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50449204 (CHEMBL1719330) Show SMILES COc1cc2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2cc1OC Show InChI InChI=1S/C17H14F3N3O3/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-10-3-5-11(6-4-10)26-17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50449205 (CHEMBL1277433) Show SMILES COc1cc2ncnc(Nc3ccc(cc3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-10(4-6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM4626 (Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC Show InChI InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-9-3-4-12(18)11(17)5-9/h3-8H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50340921 (CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES COc1cc2ncnc(Nc3ccc(NC(C)=O)cc3)c2cc1OC Show InChI InChI=1S/C18H18N4O3/c1-11(23)21-12-4-6-13(7-5-12)22-18-14-8-16(24-2)17(25-3)9-15(14)19-10-20-18/h4-10H,1-3H3,(H,21,23)(H,19,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50291090 ((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C17H17N3O3/c1-21-12-6-4-11(5-7-12)20-17-13-8-15(22-2)16(23-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50449208 (CHEMBL3127769) Show SMILES COc1cc2ncnc(Nc3ccc(cc3)C(C)=O)c2cc1OC Show InChI InChI=1S/C18H17N3O3/c1-11(22)12-4-6-13(7-5-12)21-18-14-8-16(23-2)17(24-3)9-15(14)19-10-20-18/h4-10H,1-3H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50449207 (CHEMBL3127768) Show SMILES COc1cc2ncnc(Nc3ccc(C)c(C)c3)c2cc1OC Show InChI InChI=1S/C18H19N3O2/c1-11-5-6-13(7-12(11)2)21-18-14-8-16(22-3)17(23-4)9-15(14)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-4-10(6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM3530 (6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...) Show SMILES COc1cc2ncnc(Nc3ccccc3)c2cc1OC Show InChI InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50449204 (CHEMBL1719330) Show SMILES COc1cc2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2cc1OC Show InChI InChI=1S/C17H14F3N3O3/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-10-3-5-11(6-4-10)26-17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50449205 (CHEMBL1277433) Show SMILES COc1cc2ncnc(Nc3ccc(cc3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-10(4-6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM4626 (Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC Show InChI InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-9-3-4-12(18)11(17)5-9/h3-8H,1-2H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50340921 (CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES COc1cc2ncnc(Nc3ccc(NC(C)=O)cc3)c2cc1OC Show InChI InChI=1S/C18H18N4O3/c1-11(23)21-12-4-6-13(7-5-12)22-18-14-8-16(24-2)17(25-3)9-15(14)19-10-20-18/h4-10H,1-3H3,(H,21,23)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50291090 ((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C17H17N3O3/c1-21-12-6-4-11(5-7-12)20-17-13-8-15(22-2)16(23-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50290835 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...) Show SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1OC Show InChI InChI=1S/C18H19N3O4/c1-22-14-6-5-11(7-15(14)23-2)21-18-12-8-16(24-3)17(25-4)9-13(12)19-10-20-18/h5-10H,1-4H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rajiv Gandhi Proudyogiki Vishwavidyalaya Curated by ChEMBL					Assay Description inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATP				Bioorg Med Chem 22: 1909-15 (2014) Article DOI: 10.1016/j.bmc.2014.01.044 BindingDB Entry DOI: 10.7270/Q26D5VHK
					More data for this Ligand-Target Pair

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