Compile Data Set for Download or QSAR

Found 413 hits with Last Name = 'kashima' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203558 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NC3CN4CCC3CC4)Cc2cc1OC |w:23.24,TEB:22:23:26.27:30.29,(16.31,-37.39,;14.97,-38.15,;13.64,-37.38,;12.31,-38.14,;10.99,-37.37,;9.65,-38.14,;8.33,-37.37,;8.32,-35.83,;6.99,-35.06,;6.99,-33.52,;5.66,-32.75,;5.66,-31.2,;6.99,-30.43,;6.98,-28.9,;5.64,-28.13,;8.32,-31.2,;9.8,-30.71,;10.72,-31.96,;9.81,-33.22,;8.33,-32.75,;12.26,-31.95,;13.03,-33.28,;13.02,-30.61,;14.56,-30.63,;15.38,-31.75,;16.42,-30.44,;17.92,-30.34,;17.02,-29.25,;15.54,-29.36,;14.82,-27.89,;15.74,-28.65,;9.66,-35.05,;10.99,-35.83,;12.32,-35.07,;13.64,-35.84,;14.98,-35.08,;16.31,-35.85,)| Show InChI InChI=1S/C29H35N3O5/c1-34-24-5-4-20(15-32-11-8-19-12-25(35-2)26(36-3)13-21(19)16-32)22-14-27(37-28(22)24)29(33)30-23-17-31-9-6-18(23)7-10-31/h4-5,12-14,18,23H,6-11,15-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203561 ((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)N3CCC(CC3)N3CCCC3)Cc2cc1OC Show InChI InChI=1S/C31H39N3O5/c1-36-26-7-6-22(19-32-13-8-21-16-27(37-2)28(38-3)17-23(21)20-32)25-18-29(39-30(25)26)31(35)34-14-9-24(10-15-34)33-11-4-5-12-33/h6-7,16-18,24H,4-5,8-15,19-20H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203553 (CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCC(C)(C)N)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-26(2,27)15-28-25(30)23-12-19-17(6-7-20(31-3)24(19)34-23)13-29-9-8-16-10-21(32-4)22(33-5)11-18(16)14-29/h6-7,10-12H,8-9,13-15,27H2,1-5H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203559 (2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C25H25NO5/c1-27-21-7-6-17(19-13-24(31-25(19)21)20-5-4-10-30-20)14-26-9-8-16-11-22(28-2)23(29-3)12-18(16)15-26/h4-7,10-13H,8-9,14-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2| Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203557 (3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3cccc(c3)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C32H37N3O5/c1-34(2)14-12-33-32(36)23-8-6-7-22(15-23)28-18-26-24(9-10-27(37-3)31(26)40-28)19-35-13-11-21-16-29(38-4)30(39-5)17-25(21)20-35/h6-10,15-18H,11-14,19-20H2,1-5H3,(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203562 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)24-14-20-18(6-7-21(31-3)25(20)34-24)15-29-10-8-17-12-22(32-4)23(33-5)13-19(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203556 (6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccn3)Cc2cc1OC Show InChI InChI=1S/C26H26N2O4/c1-29-22-8-7-18(20-14-23(32-26(20)22)21-6-4-5-10-27-21)15-28-11-9-17-12-24(30-2)25(31-3)13-19(17)16-28/h4-8,10,12-14H,9,11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203554 (2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3F)Cc2cc1OC Show InChI InChI=1S/C27H26FNO4/c1-30-23-9-8-18(21-14-24(33-27(21)23)20-6-4-5-7-22(20)28)15-29-11-10-17-12-25(31-2)26(32-3)13-19(17)16-29/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203563 (6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3C(F)(F)F)Cc2cc1OC Show InChI InChI=1S/C28H26F3NO4/c1-33-23-9-8-18(15-32-11-10-17-12-25(34-2)26(35-3)13-19(17)16-32)21-14-24(36-27(21)23)20-6-4-5-7-22(20)28(29,30)31/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203560 (8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3cnc(N)n4nc(nc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C21H22N6O3/c1-28-17-8-13-5-6-26(11-14(13)9-18(17)29-2)12-15-10-23-21(22)27-20(15)24-19(25-27)16-4-3-7-30-16/h3-4,7-10H,5-6,11-12H2,1-2H3,(H2,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203565 (6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...) Show SMILES COc1cccc(c1)-c1cc2c(CN3CCc4cc(OC)c(OC)cc4C3)ccc(OC)c2o1 Show InChI InChI=1S/C28H29NO5/c1-30-22-7-5-6-19(12-22)25-15-23-20(8-9-24(31-2)28(23)34-25)16-29-11-10-18-13-26(32-3)27(33-4)14-21(18)17-29/h5-9,12-15H,10-11,16-17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2| Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50203555 (6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3)Cc2cc1OC Show InChI InChI=1S/C27H27NO4/c1-29-23-10-9-20(22-15-24(32-27(22)23)18-7-5-4-6-8-18)16-28-12-11-19-13-25(30-2)26(31-3)14-21(19)17-28/h4-10,13-15H,11-12,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203558 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NC3CN4CCC3CC4)Cc2cc1OC |w:23.24,TEB:22:23:26.27:30.29,(16.31,-37.39,;14.97,-38.15,;13.64,-37.38,;12.31,-38.14,;10.99,-37.37,;9.65,-38.14,;8.33,-37.37,;8.32,-35.83,;6.99,-35.06,;6.99,-33.52,;5.66,-32.75,;5.66,-31.2,;6.99,-30.43,;6.98,-28.9,;5.64,-28.13,;8.32,-31.2,;9.8,-30.71,;10.72,-31.96,;9.81,-33.22,;8.33,-32.75,;12.26,-31.95,;13.03,-33.28,;13.02,-30.61,;14.56,-30.63,;15.38,-31.75,;16.42,-30.44,;17.92,-30.34,;17.02,-29.25,;15.54,-29.36,;14.82,-27.89,;15.74,-28.65,;9.66,-35.05,;10.99,-35.83,;12.32,-35.07,;13.64,-35.84,;14.98,-35.08,;16.31,-35.85,)| Show InChI InChI=1S/C29H35N3O5/c1-34-24-5-4-20(15-32-11-8-19-12-25(35-2)26(36-3)13-21(19)16-32)22-14-27(37-28(22)24)29(33)30-23-17-31-9-6-18(23)7-10-31/h4-5,12-14,18,23H,6-11,15-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2| Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203556 (6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccn3)Cc2cc1OC Show InChI InChI=1S/C26H26N2O4/c1-29-22-8-7-18(20-14-23(32-26(20)22)21-6-4-5-10-27-21)15-28-11-9-17-12-24(30-2)25(31-3)13-19(17)16-28/h4-8,10,12-14H,9,11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203553 (CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCC(C)(C)N)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-26(2,27)15-28-25(30)23-12-19-17(6-7-20(31-3)24(19)34-23)13-29-9-8-16-10-21(32-4)22(33-5)11-18(16)14-29/h6-7,10-12H,8-9,13-15,27H2,1-5H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203559 (2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C25H25NO5/c1-27-21-7-6-17(19-13-24(31-25(19)21)20-5-4-10-30-20)14-26-9-8-16-11-22(28-2)23(29-3)12-18(16)15-26/h4-7,10-13H,8-9,14-15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203561 ((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)N3CCC(CC3)N3CCCC3)Cc2cc1OC Show InChI InChI=1S/C31H39N3O5/c1-36-26-7-6-22(19-32-13-8-21-16-27(37-2)28(38-3)17-23(21)20-32)25-18-29(39-30(25)26)31(35)34-14-9-24(10-15-34)33-11-4-5-12-33/h6-7,16-18,24H,4-5,8-15,19-20H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203559 (2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C25H25NO5/c1-27-21-7-6-17(19-13-24(31-25(19)21)20-5-4-10-30-20)14-26-9-8-16-11-22(28-2)23(29-3)12-18(16)15-26/h4-7,10-13H,8-9,14-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203557 (3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3cccc(c3)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C32H37N3O5/c1-34(2)14-12-33-32(36)23-8-6-7-22(15-23)28-18-26-24(9-10-27(37-3)31(26)40-28)19-35-13-11-21-16-29(38-4)30(39-5)17-25(21)20-35/h6-10,15-18H,11-14,19-20H2,1-5H3,(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203554 (2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3F)Cc2cc1OC Show InChI InChI=1S/C27H26FNO4/c1-30-23-9-8-18(21-14-24(33-27(21)23)20-6-4-5-7-22(20)28)15-29-11-10-17-12-25(31-2)26(32-3)13-19(17)16-29/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203563 (6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3C(F)(F)F)Cc2cc1OC Show InChI InChI=1S/C28H26F3NO4/c1-33-23-9-8-18(15-32-11-10-17-12-25(34-2)26(35-3)13-19(17)16-32)21-14-24(36-27(21)23)20-6-4-5-7-22(20)28(29,30)31/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	304	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203556 (6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccn3)Cc2cc1OC Show InChI InChI=1S/C26H26N2O4/c1-29-22-8-7-18(20-14-23(32-26(20)22)21-6-4-5-10-27-21)15-28-11-9-17-12-24(30-2)25(31-3)13-19(17)16-28/h4-8,10,12-14H,9,11,15-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203560 (8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3cnc(N)n4nc(nc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C21H22N6O3/c1-28-17-8-13-5-6-26(11-14(13)9-18(17)29-2)12-15-10-23-21(22)27-20(15)24-19(25-27)16-4-3-7-30-16/h3-4,7-10H,5-6,11-12H2,1-2H3,(H2,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203560 (8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3cnc(N)n4nc(nc34)-c3ccco3)Cc2cc1OC Show InChI InChI=1S/C21H22N6O3/c1-28-17-8-13-5-6-26(11-14(13)9-18(17)29-2)12-15-10-23-21(22)27-20(15)24-19(25-27)16-4-3-7-30-16/h3-4,7-10H,5-6,11-12H2,1-2H3,(H2,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203562 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)24-14-20-18(6-7-21(31-3)25(20)34-24)15-29-10-8-17-12-22(32-4)23(33-5)13-19(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	454	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203557 (3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3cccc(c3)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C32H37N3O5/c1-34(2)14-12-33-32(36)23-8-6-7-22(15-23)28-18-26-24(9-10-27(37-3)31(26)40-28)19-35-13-11-21-16-29(38-4)30(39-5)17-25(21)20-35/h6-10,15-18H,11-14,19-20H2,1-5H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	584	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203555 (6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3)Cc2cc1OC Show InChI InChI=1S/C27H27NO4/c1-29-23-10-9-20(22-15-24(32-27(22)23)18-7-5-4-6-8-18)16-28-12-11-19-13-25(30-2)26(31-3)14-21(19)17-28/h4-10,13-15H,11-12,16-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	752	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203565 (6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...) Show SMILES COc1cccc(c1)-c1cc2c(CN3CCc4cc(OC)c(OC)cc4C3)ccc(OC)c2o1 Show InChI InChI=1S/C28H29NO5/c1-30-22-7-5-6-19(12-22)25-15-23-20(8-9-24(31-2)28(23)34-25)16-29-11-10-18-13-26(32-3)27(33-4)14-21(18)17-29/h5-9,12-15H,10-11,16-17H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	804	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203554 (2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3F)Cc2cc1OC Show InChI InChI=1S/C27H26FNO4/c1-30-23-9-8-18(21-14-24(33-27(21)23)20-6-4-5-7-22(20)28)15-29-11-10-17-12-25(31-2)26(32-3)13-19(17)16-29/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	857	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203558 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NC3CN4CCC3CC4)Cc2cc1OC |w:23.24,TEB:22:23:26.27:30.29,(16.31,-37.39,;14.97,-38.15,;13.64,-37.38,;12.31,-38.14,;10.99,-37.37,;9.65,-38.14,;8.33,-37.37,;8.32,-35.83,;6.99,-35.06,;6.99,-33.52,;5.66,-32.75,;5.66,-31.2,;6.99,-30.43,;6.98,-28.9,;5.64,-28.13,;8.32,-31.2,;9.8,-30.71,;10.72,-31.96,;9.81,-33.22,;8.33,-32.75,;12.26,-31.95,;13.03,-33.28,;13.02,-30.61,;14.56,-30.63,;15.38,-31.75,;16.42,-30.44,;17.92,-30.34,;17.02,-29.25,;15.54,-29.36,;14.82,-27.89,;15.74,-28.65,;9.66,-35.05,;10.99,-35.83,;12.32,-35.07,;13.64,-35.84,;14.98,-35.08,;16.31,-35.85,)| Show InChI InChI=1S/C29H35N3O5/c1-34-24-5-4-20(15-32-11-8-19-12-25(35-2)26(36-3)13-21(19)16-32)22-14-27(37-28(22)24)29(33)30-23-17-31-9-6-18(23)7-10-31/h4-5,12-14,18,23H,6-11,15-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	857	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203563 (6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3C(F)(F)F)Cc2cc1OC Show InChI InChI=1S/C28H26F3NO4/c1-33-23-9-8-18(15-32-11-10-17-12-25(34-2)26(35-3)13-19(17)16-32)21-14-24(36-27(21)23)20-6-4-5-7-22(20)28(29,30)31/h4-9,12-14H,10-11,15-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	949	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203561 ((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)N3CCC(CC3)N3CCCC3)Cc2cc1OC Show InChI InChI=1S/C31H39N3O5/c1-36-26-7-6-22(19-32-13-8-21-16-27(37-2)28(38-3)17-23(21)20-32)25-18-29(39-30(25)26)31(35)34-14-9-24(10-15-34)33-11-4-5-12-33/h6-7,16-18,24H,4-5,8-15,19-20H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203553 (CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCC(C)(C)N)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-26(2,27)15-28-25(30)23-12-19-17(6-7-20(31-3)24(19)34-23)13-29-9-8-16-10-21(32-4)22(33-5)11-18(16)14-29/h6-7,10-12H,8-9,13-15,27H2,1-5H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203555 (6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3)Cc2cc1OC Show InChI InChI=1S/C27H27NO4/c1-29-23-10-9-20(22-15-24(32-27(22)23)18-7-5-4-6-8-18)16-28-12-11-19-13-25(30-2)26(31-3)14-21(19)17-28/h4-10,13-15H,11-12,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50203562 (4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...) Show SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC Show InChI InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)24-14-20-18(6-7-21(31-3)25(20)34-24)15-29-10-8-17-12-22(32-4)23(33-5)13-19(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50203565 (6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...) Show SMILES COc1cccc(c1)-c1cc2c(CN3CCc4cc(OC)c(OC)cc4C3)ccc(OC)c2o1 Show InChI InChI=1S/C28H29NO5/c1-30-22-7-5-6-19(12-22)25-15-23-20(8-9-24(31-2)28(23)34-25)16-29-11-10-18-13-26(32-3)27(33-4)14-21(18)17-29/h5-9,12-15H,10-11,16-17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cells				Bioorg Med Chem Lett 17: 1616-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.094 BindingDB Entry DOI: 10.7270/Q2TD9Z5F
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50241727 ((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...) Show SMILES Cn1cc(C[C@H](N)C(O)=O)c2ccccc12 |r| Show InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokushima Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic condition				Bioorg Med Chem 16: 8661-9 (2008) Article DOI: 10.1016/j.bmc.2008.07.087 BindingDB Entry DOI: 10.7270/Q2W66KKP
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50247140 (CHEMBL470328 | TX-2236 | [5-(1-Oxido-1,2,4-benzotr...) Show SMILES Cn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCCCNc2n[n+]([O-])c3ccccc3n2)c2ccccc12 |r| Show InChI InChI=1S/C29H37N7O4/c1-29(2,3)40-28(38)33-23(18-20-19-35(4)24-14-8-6-12-21(20)24)26(37)30-16-10-5-11-17-31-27-32-22-13-7-9-15-25(22)36(39)34-27/h6-9,12-15,19,23H,5,10-11,16-18H2,1-4H3,(H,30,37)(H,33,38)(H,31,32,34)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokushima Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic condition				Bioorg Med Chem 16: 8661-9 (2008) Article DOI: 10.1016/j.bmc.2008.07.087 BindingDB Entry DOI: 10.7270/Q2W66KKP
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50247142 (CHEMBL470329 | TX-2228 | [4-(1-Oxido-1,2,4-benzotr...) Show SMILES Cn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCCNc2n[n+]([O-])c3ccccc3n2)c2ccccc12 |r| Show InChI InChI=1S/C28H35N7O4/c1-28(2,3)39-27(37)32-22(17-19-18-34(4)23-13-7-5-11-20(19)23)25(36)29-15-9-10-16-30-26-31-21-12-6-8-14-24(21)35(38)33-26/h5-8,11-14,18,22H,9-10,15-17H2,1-4H3,(H,29,36)(H,32,37)(H,30,31,33)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokushima Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic condition				Bioorg Med Chem 16: 8661-9 (2008) Article DOI: 10.1016/j.bmc.2008.07.087 BindingDB Entry DOI: 10.7270/Q2W66KKP
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50247141 (CHEMBL443424 | TX-2235 | [5-(1,4-Dioxido-1,2,4-ben...) Show SMILES Cn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCCCNc2n[n+]([O-])c3ccccc3[n+]2[O-])c2ccccc12 |r| Show InChI InChI=1S/C29H37N7O5/c1-29(2,3)41-28(38)32-22(18-20-19-34(4)23-13-7-6-12-21(20)23)26(37)30-16-10-5-11-17-31-27-33-36(40)25-15-9-8-14-24(25)35(27)39/h6-9,12-15,19,22H,5,10-11,16-18H2,1-4H3,(H,30,37)(H,31,33)(H,32,38)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.97E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokushima Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic condition				Bioorg Med Chem 16: 8661-9 (2008) Article DOI: 10.1016/j.bmc.2008.07.087 BindingDB Entry DOI: 10.7270/Q2W66KKP
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50247143 (CHEMBL513210 | TX-2234 | [4-(1,4-Dioxido-1,2,4-ben...) Show SMILES Cn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCCNc2n[n+]([O-])c3ccccc3[n+]2[O-])c2ccccc12 |r| Show InChI InChI=1S/C28H35N7O5/c1-28(2,3)40-27(37)31-21(17-19-18-33(4)22-12-6-5-11-20(19)22)25(36)29-15-9-10-16-30-26-32-35(39)24-14-8-7-13-23(24)34(26)38/h5-8,11-14,18,21H,9-10,15-17H2,1-4H3,(H,29,36)(H,30,32)(H,31,37)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.67E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokushima Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic condition				Bioorg Med Chem 16: 8661-9 (2008) Article DOI: 10.1016/j.bmc.2008.07.087 BindingDB Entry DOI: 10.7270/Q2W66KKP
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.177	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MMP-9 by fluorometric assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01215 BindingDB Entry DOI: 10.7270/Q2Q81HPF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.422	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MMP-2 by fluorometric assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01215 BindingDB Entry DOI: 10.7270/Q2Q81HPF
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM29994 (2-Cyclohexylcarbonylbenzimidazole, 7e) Show SMILES CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@]1(CC)CC[C@@](C)(O)CC1 |r,wU:20.23,25.29,wD:20.22,25.28,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;6.37,4.44,;5.83,2.84,;6.66,1.54,;5.96,.17,;5.96,-1.37,;7.45,-.23,;4.42,.1,;3.59,1.39,)| Show InChI InChI=1S/C23H33ClN4O2/c1-4-23(8-6-22(3,30)7-9-23)20(29)21-25-17-14-16(24)19(15-18(17)26-21)28-12-10-27(5-2)11-13-28/h14-15,30H,4-13H2,1-3H3,(H,25,26)/t22-,23-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	2.40	n/a	n/a	7.4	37
Banyu Pharmaceutical Co.					Assay Description Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...				Bioorg Med Chem Lett 19: 3096-9 (2009) Article DOI: 10.1016/j.bmcl.2009.04.023 BindingDB Entry DOI: 10.7270/Q24J0CFR
					More data for this Ligand-Target Pair

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