BindingDB PrimarySearch

Found 119 hits with Last Name = 'katsuno' and Initial = 'k'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126775 BindingDB Entry DOI: 10.7270/Q2Q243K6
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126775 BindingDB Entry DOI: 10.7270/Q2Q243K6
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50232542 (CHEMBL4090531 \| US10323022, Example 135) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkA expressed in DHFR deficient CHO cells assessed as inhibition of human beta-nerve growth factor-induced calcium i...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of TRKA E735A mutant (unknown origin) expressed in baculovirus infected sf9 cells assessed as kinase domain dimerization by HTRF assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126775 BindingDB Entry DOI: 10.7270/Q2Q243K6
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559528 (CHEMBL3950588) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559538 (CHEMBL3908950) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50232542 (CHEMBL4090531 \| US10323022, Example 135) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkB expressed in DHFR deficient CHO cells assessed as inhibition of human brain-derived neurotrophic factor-induced ...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkC expressed in DHFR deficient CHO cells assessed as inhibition of human neurotrophin-3-induced calcium influx by F...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559527 (CHEMBL3907970) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50392788 (CHEMBL457614) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkA expressed in DHFR deficient CHO cells assessed as inhibition of human beta-nerve growth factor-induced calcium i...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559522 (CHEMBL3960449) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559524 (CHEMBL3923809) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559529 (CHEMBL3896936) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559525 (CHEMBL3934976) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559523 (CHEMBL3915296) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559526 (CHEMBL3969998) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559539 (CHEMBL3980689) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559517 (Remogliflozin \| Remogliflozin a) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559519 (CHEMBL4786882) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559537 (CHEMBL3972664) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559518 (CHEMBL4787524) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50022672 (CHEMBL3298266) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559532 (CHEMBL4765036) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559539 (CHEMBL3980689) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559520 (CHEMBL4785821) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50022672 (CHEMBL3298266) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50022672 (CHEMBL3298266) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkB expressed in DHFR deficient CHO cells assessed as inhibition of human brain-derived neurotrophic factor-induced ...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50022672 (CHEMBL3298266) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkC expressed in DHFR deficient CHO cells assessed as inhibition of human neurotrophin-3-induced calcium influx by F...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559532 (CHEMBL4765036) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559536 (CHEMBL4795938) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559535 (CHEMBL4793115) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50510995 (CHEMBL4556229) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126775 BindingDB Entry DOI: 10.7270/Q2Q243K6
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559528 (CHEMBL3950588) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50022672 (CHEMBL3298266) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	287	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559529 (CHEMBL3896936) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559527 (CHEMBL3907970) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559537 (CHEMBL3972664) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559538 (CHEMBL3908950) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559536 (CHEMBL4795938) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559525 (CHEMBL3934976) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	626	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559530 (CHEMBL4752053) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	757	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559531 (CHEMBL4750405) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559521 (CHEMBL4760667) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559524 (CHEMBL3923809) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50232542 (CHEMBL4090531 \| US10323022, Example 135) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of recombinant human TrkB expressed in DHFR deficient CHO cells assessed as inhibition of human brain-derived neurotrophic factor-induced ...				Bioorg Med Chem Lett 27: 1233-1236 (2017) Article DOI: 10.1016/j.bmcl.2017.01.056 BindingDB Entry DOI: 10.7270/Q2TT4T51
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559535 (CHEMBL4793115) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559531 (CHEMBL4750405) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
TBA					More data for this Ligand-Target Pair

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