| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium/glucose cotransporter 1 |
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| Ligand | BDBM50559531 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2069750 (CHEMBL4725003) |
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| IC50 | 1630±n/a nM |
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| Citation |  Shimizu, K; Fujikura, H; Fushimi, N; Nishimura, T; Tatani, K; Katsuno, K; Fujimori, Y; Watanabe, S; Hiratochi, M; Nakabayashi, T; Kamada, N; Arakawa, K; Hikawa, H; Azumaya, I; Isaji, M Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor. Bioorg Med Chem34:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium/glucose cotransporter 1 |
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| Name: | Sodium/glucose cotransporter 1 |
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| Synonyms: | High affinity sodium-glucose cotransporter | NAGT | Na(+)/glucose cotransporter 1 | SC5A1_HUMAN | SGLT1 | SLC5A1 | Sodium-dependent glucose cotransporter 1 (SGLT1) | Sodium/glucose cotransporter 1 | Sodium/glucose cotransporter 1 (SGLT1) | Solute carrier family 5 member 1 |
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| Type: | Protein |
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| Mol. Mass.: | 73503.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P13866 |
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| Residue: | 664 |
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| Sequence: | MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFL
AGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIY
IKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLA
IFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAI
PTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQR
CLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVG
CTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEK
ELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRV
NEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFIT
IVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKG
IFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCH
AYFA
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| BDBM50559531 |
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| n/a |
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| Name | BDBM50559531 |
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| Synonyms: | CHEMBL4750405 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24N2O6 |
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| Mol. Mass. | 364.393 |
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| SMILES | Cc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1C |r| |
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| Structure | 
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