Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'keats' and Initial = 'ja'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132351 (({4-[6-(2,6-Dichloro-phenyl)-8-(3-dimethylamino-pr...) Show SMILES CN(C)CCCn1c2nc(Nc3ccc(cc3)P(O)(=O)CP(O)(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(3.9,-7.22,;3.9,-5.68,;2.57,-4.91,;5.23,-4.91,;5.23,-3.37,;6.56,-2.59,;6.56,-1.05,;5.21,-.28,;3.88,-1.05,;2.55,-.29,;1.22,-1.06,;-.11,-.29,;-.11,1.25,;-1.44,2.01,;-2.78,1.23,;-2.77,-.31,;-1.44,-1.07,;-4.12,2,;-4.89,.67,;-3.35,3.34,;-5.45,2.77,;-5.45,4.31,;-6.99,4.32,;-5.86,5.8,;-4.12,5.09,;2.55,1.26,;3.88,2.03,;5.21,1.26,;6.54,2.03,;7.89,1.25,;9.22,2.02,;9.22,3.57,;7.89,4.33,;10.55,4.36,;11.88,3.57,;11.88,2.02,;10.55,1.25,;10.55,-.29,;7.89,-.28,;9.22,-1.05,)| Show InChI InChI=1S/C25H27Cl2N5O6P2/c1-31(2)11-4-12-32-23-16(13-19(24(32)33)22-20(26)5-3-6-21(22)27)14-28-25(30-23)29-17-7-9-18(10-8-17)39(34,35)15-40(36,37)38/h3,5-10,13-14H,4,11-12,15H2,1-2H3,(H,34,35)(H,28,29,30)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132348 (({4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...) Show SMILES Cn1c2nc(Nc3ccc(cc3)P(O)(=O)CP(O)(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(3.94,-2.74,;3.93,-1.2,;2.6,-.43,;1.27,-1.2,;-.06,-.43,;-1.39,-1.21,;-2.73,-.45,;-2.73,1.1,;-4.06,1.86,;-5.41,1.09,;-5.38,-.47,;-4.05,-1.22,;-6.74,1.86,;-7.53,.53,;-5.97,3.19,;-8.09,2.61,;-9.4,1.82,;-10.19,3.17,;-10.91,1.42,;-9.02,.34,;-.07,1.11,;1.27,1.88,;2.6,1.11,;3.93,1.88,;5.26,1.11,;6.59,1.88,;6.59,3.42,;5.26,4.19,;7.92,4.19,;9.26,3.42,;9.26,1.88,;7.92,1.11,;7.92,-.43,;5.26,-.43,;6.6,-1.2,)| Show InChI InChI=1S/C21H18Cl2N4O6P2/c1-27-19-12(9-15(20(27)28)18-16(22)3-2-4-17(18)23)10-24-21(26-19)25-13-5-7-14(8-6-13)34(29,30)11-35(31,32)33/h2-10H,11H2,1H3,(H,29,30)(H,24,25,26)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132322 (({2-[(2-{4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2...) Show SMILES CN(CCOP(O)(=O)CP(O)(O)=O)CCc1ccc(cc1)-n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C24H29N5O7P2/c1-28(11-12-36-38(34,35)16-37(31,32)33)10-9-17-5-7-19(8-6-17)29-14-21(18-3-2-4-20(30)13-18)22-23(25)26-15-27-24(22)29/h2-8,13-15,30H,9-12,16H2,1H3,(H,34,35)(H2,25,26,27)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3071 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 38 | 2-ani...) Show SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.81,-2.74,;-6.81,-4.28,;-8.14,-5.05,;-9.48,-4.29,;-9.48,-2.75,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)| Show InChI InChI=1S/C20H14Cl2N4O/c1-26-18-12(11-23-20(25-18)24-13-6-3-2-4-7-13)10-14(19(26)27)17-15(21)8-5-9-16(17)22/h2-11H,1H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221656 (CHEMBL3706663) Show SMILES Nc1ncnc2n(nc(-c3cccc(O)c3)c12)-c1cccc(c1)P(O)(=O)CC(O)=O Show InChI InChI=1S/C19H16N5O5P/c20-18-16-17(11-3-1-5-13(25)7-11)23-24(19(16)22-10-21-18)12-4-2-6-14(8-12)30(28,29)9-15(26)27/h1-8,10,25H,9H2,(H,26,27)(H,28,29)(H2,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132324 (3-{4-Amino-7-[4-(2-hydroxy-ethyl)-phenyl]-7H-pyrro...) Show SMILES Nc1ncnc2n(cc(-c3cccc(O)c3)c12)-c1ccc(CCO)cc1 Show InChI InChI=1S/C20H18N4O2/c21-19-18-17(14-2-1-3-16(26)10-14)11-24(20(18)23-12-22-19)15-6-4-13(5-7-15)8-9-25/h1-7,10-12,25-26H,8-9H2,(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132339 (3-[4-Amino-7-(4-{2-[(2-hydroxy-ethyl)-methyl-amino...) Show SMILES CN(CCO)CCc1ccc(cc1)-n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H25N5O2/c1-27(11-12-29)10-9-16-5-7-18(8-6-16)28-14-20(17-3-2-4-19(30)13-17)21-22(24)25-15-26-23(21)28/h2-8,13-15,29-30H,9-12H2,1H3,(H2,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132334 (CHEMBL104215 | [(2-{4-[4-Amino-5-(3-hydroxy-phenyl...) Show SMILES Nc1ncnc2n(cc(-c3cccc(O)c3)c12)-c1ccc(CCOP(O)(=O)CP(O)(O)=O)cc1 Show InChI InChI=1S/C21H22N4O7P2/c22-20-19-18(15-2-1-3-17(26)10-15)11-25(21(19)24-12-23-20)16-6-4-14(5-7-16)8-9-32-34(30,31)13-33(27,28)29/h1-7,10-12,26H,8-9,13H2,(H,30,31)(H2,22,23,24)(H2,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132352 (({3-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...) Show SMILES Cn1c2nc(Nc3cccc(c3)P(O)(=O)CP(O)(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(2.81,-5.78,;2.81,-4.24,;1.47,-3.47,;.14,-4.24,;-1.19,-3.48,;-2.53,-4.26,;-3.87,-3.49,;-5.19,-4.26,;-6.52,-3.52,;-6.54,-1.96,;-5.21,-1.18,;-3.87,-1.95,;-5.21,.37,;-6.75,.39,;-3.66,.37,;-5.21,1.91,;-6.55,2.68,;-5.78,4.01,;-7.64,3.78,;-7.66,1.61,;-1.21,-1.93,;.14,-1.15,;1.47,-1.93,;2.81,-1.15,;4.15,-1.94,;5.48,-1.17,;6.81,-1.94,;6.81,-3.48,;8.14,-1.17,;8.14,.39,;6.81,1.16,;5.48,.37,;4.15,1.15,;4.15,-3.47,;5.48,-4.24,)| Show InChI InChI=1S/C21H18Cl2N4O6P2/c1-27-19-12(8-15(20(27)28)18-16(22)6-3-7-17(18)23)10-24-21(26-19)25-13-4-2-5-14(9-13)34(29,30)11-35(31,32)33/h2-10H,11H2,1H3,(H,29,30)(H,24,25,26)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132330 (7-tert-Butyl-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-...) Show SMILES Cc1ccc(cc1)-c1cn(c2ncnc(N)c12)C(C)(C)C Show InChI InChI=1S/C17H20N4/c1-11-5-7-12(8-6-11)13-9-21(17(2,3)4)16-14(13)15(18)19-10-20-16/h5-10H,1-4H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN(C)CCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C24H27N5O2/c1-28(12-13-30)11-10-17-6-8-19(9-7-17)29-15-21(18-4-3-5-20(14-18)31-2)22-23(25)26-16-27-24(22)29/h3-9,14-16,30H,10-13H2,1-2H3,(H2,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132353 (CHEMBL102801 | {4-[6-(2,6-Dichloro-phenyl)-8-methy...) Show SMILES Cn1c2nc(Nc3ccc(OCC(O)=O)c(c3)P(O)(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(4.7,-3.27,;4.67,-1.73,;3.34,-.96,;2.01,-1.73,;.68,-.96,;-.65,-1.73,;-1.98,-.98,;-1.98,.58,;-3.31,1.33,;-4.64,.55,;-5.99,1.32,;-5.99,2.86,;-7.33,3.63,;-8.67,2.85,;-7.34,5.17,;-4.64,-.99,;-3.31,-1.75,;-5.97,-1.77,;-7.3,-2.57,;-7.46,-.86,;-5.3,-3.15,;.68,.58,;2.01,1.35,;3.34,.58,;4.67,1.35,;6.02,.58,;7.35,1.35,;7.35,2.89,;6.02,3.66,;8.68,3.66,;10.02,2.89,;10.02,1.35,;8.68,.58,;8.68,-.96,;6.02,-.96,;7.36,-1.73,)| Show InChI InChI=1S/C22H17Cl2N4O7P/c1-28-20-11(7-13(21(28)31)19-14(23)3-2-4-15(19)24)9-25-22(27-20)26-12-5-6-16(35-10-18(29)30)17(8-12)36(32,33)34/h2-9H,10H2,1H3,(H,29,30)(H,25,26,27)(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132335 (CHEMBL104857 | [(3-{4-[4-Amino-5-(3-methoxy-phenyl...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(cc2)C(=O)NCCCP(O)(=O)CP(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C24H27N5O7P2/c1-36-19-5-2-4-17(12-19)20-13-29(23-21(20)22(25)27-14-28-23)18-8-6-16(7-9-18)24(30)26-10-3-11-37(31,32)15-38(33,34)35/h2,4-9,12-14H,3,10-11,15H2,1H3,(H,26,30)(H,31,32)(H2,25,27,28)(H2,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132333 (({2-[(2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN(C)CCOP(O)(=O)CP(O)(O)=O)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C25H31N5O7P2/c1-29(12-13-37-39(34,35)17-38(31,32)33)11-10-18-6-8-20(9-7-18)30-15-22(19-4-3-5-21(14-19)36-2)23-24(26)27-16-28-25(23)30/h3-9,14-16H,10-13,17H2,1-2H3,(H,34,35)(H2,26,27,28)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221655 (CHEMBL3706661) Show SMILES Cc1ccc(cc1)-c1nn(-c2cccc(c2)C(=O)NCc2ccc(c(c2)P(O)(O)=O)P(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C26H24N6O7P2/c1-15-5-8-17(9-6-15)23-22-24(27)29-14-30-25(22)32(31-23)19-4-2-3-18(12-19)26(33)28-13-16-7-10-20(40(34,35)36)21(11-16)41(37,38)39/h2-12,14H,13H2,1H3,(H,28,33)(H2,27,29,30)(H2,34,35,36)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132328 (CHEMBL321116 | [(3-{3-[4-Amino-5-(3-methoxy-phenyl...) Show SMILES COc1cccc(c1)-c1cn(-c2cccc(c2)C(=O)NCCCP(O)(=O)CP(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C24H27N5O7P2/c1-36-19-8-3-5-16(12-19)20-13-29(23-21(20)22(25)27-14-28-23)18-7-2-6-17(11-18)24(30)26-9-4-10-37(31,32)15-38(33,34)35/h2-3,5-8,11-14H,4,9-10,15H2,1H3,(H,26,30)(H,31,32)(H2,25,27,28)(H2,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221654 (CHEMBL3706662) Show SMILES Cc1ccc(cc1)-c1nn(-c2cccc(c2)C(=O)NCCCP(O)(=O)CP(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C23H26N6O6P2/c1-15-6-8-16(9-7-15)20-19-21(24)26-13-27-22(19)29(28-20)18-5-2-4-17(12-18)23(30)25-10-3-11-36(31,32)14-37(33,34)35/h2,4-9,12-13H,3,10-11,14H2,1H3,(H,25,30)(H,31,32)(H2,24,26,27)(H2,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132326 (CHEMBL421405 | {[4-(4-Amino-3-p-tolyl-pyrazolo[3,4...) Show SMILES Cc1ccc(cc1)-c1nn(CCCCOP(O)(=O)CP(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C17H23N5O6P2/c1-12-4-6-13(7-5-12)15-14-16(18)19-10-20-17(14)22(21-15)8-2-3-9-28-30(26,27)11-29(23,24)25/h4-7,10H,2-3,8-9,11H2,1H3,(H,26,27)(H2,18,19,20)(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132338 (CHEMBL102183 | [(2-{4-[4-Amino-5-(3-methoxy-phenyl...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCOP(O)(=O)CP(O)(O)=O)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C22H24N4O7P2/c1-32-18-4-2-3-16(11-18)19-12-26(22-20(19)21(23)24-13-25-22)17-7-5-15(6-8-17)9-10-33-35(30,31)14-34(27,28)29/h2-8,11-13H,9-10,14H2,1H3,(H,30,31)(H2,23,24,25)(H2,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132350 (({4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...) Show SMILES Cn1c2nc(Nc3ccc(CP(O)(=O)CP(O)(O)=O)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(5.26,-5.02,;5.25,-3.48,;3.9,-2.71,;2.57,-3.48,;1.24,-2.71,;-.09,-3.5,;-1.42,-2.74,;-1.42,-1.19,;-2.75,-.43,;-4.08,-1.2,;-5.43,-.43,;-5.43,1.11,;-6.97,1.16,;-3.89,1.09,;-5.41,2.64,;-6.74,3.42,;-5.94,4.76,;-7.81,4.54,;-7.86,2.37,;-4.08,-2.75,;-2.75,-3.51,;1.24,-1.17,;2.57,-.4,;3.9,-1.17,;5.23,-.4,;6.58,-1.17,;7.91,-.4,;9.24,-1.17,;9.24,-2.71,;10.58,-.4,;10.58,1.14,;9.24,1.91,;7.91,1.14,;6.58,1.91,;6.58,-2.71,;7.92,-3.48,)| Show InChI InChI=1S/C22H20Cl2N4O6P2/c1-28-20-14(9-16(21(28)29)19-17(23)3-2-4-18(19)24)10-25-22(27-20)26-15-7-5-13(6-8-15)11-35(30,31)12-36(32,33)34/h2-10H,11-12H2,1H3,(H,30,31)(H,25,26,27)(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132325 ((4-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(cc2)C(=O)Nc2ccc(c(c2)P(O)(O)=O)P(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C26H23N5O8P2/c1-39-19-4-2-3-16(11-19)20-13-31(25-23(20)24(27)28-14-29-25)18-8-5-15(6-9-18)26(32)30-17-7-10-21(40(33,34)35)22(12-17)41(36,37)38/h2-14H,1H3,(H,30,32)(H2,27,28,29)(H2,33,34,35)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132329 (2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C21H20N4O2/c1-27-17-4-2-3-15(11-17)18-12-25(21-19(18)20(22)23-13-24-21)16-7-5-14(6-8-16)9-10-26/h2-8,11-13,26H,9-10H2,1H3,(H2,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132349 (CHEMBL320374 | {5-[6-(2,6-Dichloro-phenyl)-8-methy...) Show SMILES Cn1c2nc(Nc3ccc(c(c3)P(O)(O)=O)P(O)(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(3.82,-1.69,;3.82,-.15,;2.48,.62,;1.15,-.15,;-.19,.61,;-1.52,-.17,;-2.87,.6,;-2.87,2.14,;-4.2,2.91,;-5.53,2.13,;-5.52,.58,;-4.19,-.17,;-6.85,-.19,;-8.2,-.99,;-8.36,.72,;-6.19,-1.57,;-6.87,2.9,;-6.07,4.25,;-7.94,4.02,;-7.99,1.84,;-.2,2.17,;1.15,2.94,;2.48,2.17,;3.81,2.94,;5.15,2.15,;6.48,2.92,;6.48,4.48,;5.15,5.24,;7.82,5.25,;9.15,4.48,;9.15,2.92,;7.82,2.15,;7.82,.61,;5.15,.62,;6.48,-.15,)| Show InChI InChI=1S/C20H16Cl2N4O7P2/c1-26-18-10(7-12(19(26)27)17-13(21)3-2-4-14(17)22)9-23-20(25-18)24-11-5-6-15(34(28,29)30)16(8-11)35(31,32)33/h2-9H,1H3,(H,23,24,25)(H2,28,29,30)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 13: 3071-4 (2003) BindingDB Entry DOI: 10.7270/Q21J995T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132332 (4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(cc2)C(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C20H16N4O3/c1-27-15-4-2-3-13(9-15)16-10-24(19-17(16)18(21)22-11-23-19)14-7-5-12(6-8-14)20(25)26/h2-11H,1H3,(H,25,26)(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221653 (CHEMBL3706664) Show SMILES COc1cccc(c1)-c1nn(-c2cccc(c2)P(O)(=O)CC(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C20H18N5O5P/c1-30-14-6-2-4-12(8-14)18-17-19(21)22-11-23-20(17)25(24-18)13-5-3-7-15(9-13)31(28,29)10-16(26)27/h2-9,11H,10H2,1H3,(H,26,27)(H,28,29)(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132331 ((4-{3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]...) Show SMILES COc1cccc(c1)-c1cn(-c2cccc(c2)C(=O)Nc2ccc(c(c2)P(O)(O)=O)P(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C26H23N5O8P2/c1-39-19-7-3-4-15(11-19)20-13-31(25-23(20)24(27)28-14-29-25)18-6-2-5-16(10-18)26(32)30-17-8-9-21(40(33,34)35)22(12-17)41(36,37)38/h2-14H,1H3,(H,30,32)(H2,27,28,29)(H2,33,34,35)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132327 (3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...) Show SMILES COc1cccc(c1)-c1cn(-c2cccc(c2)C(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C20H16N4O3/c1-27-15-7-3-4-12(9-15)16-10-24(19-17(16)18(21)22-11-23-19)14-6-2-5-13(8-14)20(25)26/h2-11H,1H3,(H,25,26)(H2,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132323 (CHEMBL104077 | [(4-{3-[4-Amino-5-(3-methoxy-phenyl...) Show SMILES COc1cccc(c1)-c1cn(-c2cccc(c2)C(=O)Nc2ccc(cc2)C(P(O)(O)=O)P(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C27H25N5O8P2/c1-40-21-7-3-4-17(13-21)22-14-32(25-23(22)24(28)29-15-30-25)20-6-2-5-18(12-20)26(33)31-19-10-8-16(9-11-19)27(41(34,35)36)42(37,38)39/h2-15,27H,1H3,(H,31,33)(H2,28,29,30)(H2,34,35,36)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50132337 (CHEMBL101795 | [(4-{4-[4-Amino-5-(3-methoxy-phenyl...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(cc2)C(=O)Nc2ccc(cc2)C(P(O)(O)=O)P(O)(O)=O)c2ncnc(N)c12 Show InChI InChI=1S/C27H25N5O8P2/c1-40-21-4-2-3-18(13-21)22-14-32(25-23(22)24(28)29-15-30-25)20-11-7-16(8-12-20)26(33)31-19-9-5-17(6-10-19)27(41(34,35)36)42(37,38)39/h2-15,27H,1H3,(H,31,33)(H2,28,29,30)(H2,34,35,36)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
					More data for this Ligand-Target Pair