Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin K (Homo sapiens (Human)) | BDBM50260286 (CHEMBL508746 | cycloaltilisin 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of cathepsin K (unknown origin) by fluorimetric assay | J Nat Prod 65: 624-7 (2002) BindingDB Entry DOI: 10.7270/Q2FT8KRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM50260285 (1-(2,4-dihydroxyphenyl)-3-(2-(3,7-dimethylocta-2,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of cathepsin K (unknown origin) by fluorimetric assay | J Nat Prod 65: 624-7 (2002) BindingDB Entry DOI: 10.7270/Q2FT8KRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM50260287 (CHEMBL494579 | cycloaltilisin 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of cathepsin K (unknown origin) by fluorimetric assay | J Nat Prod 65: 624-7 (2002) BindingDB Entry DOI: 10.7270/Q2FT8KRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage scavenger receptor types I and II (Homo sapiens (Human)) | BDBM50292390 (CHEMBL454185 | Rigidone) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full-length MSR1 transfected in HEK293 cells by fluorimetry | J Nat Prod 60: 309-11 (1997) Article DOI: 10.1021/np960653m BindingDB Entry DOI: 10.7270/Q2S182HP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage scavenger receptor types I and II (Homo sapiens (Human)) | BDBM50292391 ((S)-1-methyl-4-(6-methylhept-5-en-2-yl)phenazine-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full-length MSR1 transfected in HEK293 cells by fluorimetry | J Nat Prod 60: 309-11 (1997) Article DOI: 10.1021/np960653m BindingDB Entry DOI: 10.7270/Q2S182HP | |||||||||||
More data for this Ligand-Target Pair |