Compile Data Set for Download or QSAR

Found 160 hits with Last Name = 'kramer' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308167 ((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308181 ((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308183 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...) Show SMILES NC1CN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C20H18N4O2S/c21-14-11-24(12-14)15-8-9-18-17(10-15)20(23-22-18)27(25,26)19-7-3-5-13-4-1-2-6-16(13)19/h1-10,14H,11-12,21H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308177 (1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES Cc1ccc(c2ccccc12)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C23H24N4O2S/c1-15-6-9-22(19-5-3-2-4-18(15)19)30(28,29)23-20-14-17(7-8-21(20)25-26-23)27-12-10-16(24)11-13-27/h2-9,14,16H,10-13,24H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308175 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c23-16-10-12-26(13-11-16)17-8-9-20-19(14-17)22(25-24-20)29(27,28)21-7-3-5-15-4-1-2-6-18(15)21/h1-9,14,16H,10-13,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308178 (1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2c(Cl)cccc12 Show InChI InChI=1S/C22H21ClN4O2S/c23-19-5-1-4-17-16(19)3-2-6-21(17)30(28,29)22-18-13-15(7-8-20(18)25-26-22)27-11-9-14(24)10-12-27/h1-8,13-14H,9-12,24H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308179 (1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H19ClN4O2S/c19-12-2-1-3-15(10-12)26(24,25)18-16-11-14(4-5-17(16)21-22-18)23-8-6-13(20)7-9-23/h1-5,10-11,13H,6-9,20H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308180 (1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C21H26N4O2S/c1-14(2)15-3-6-18(7-4-15)28(26,27)21-19-13-17(5-8-20(19)23-24-21)25-11-9-16(22)10-12-25/h3-8,13-14,16H,9-12,22H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308170 ((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-22-11-10-19(27-13-12-18(25)15-27)14-21(22)24(26-28)31(29,30)23-9-5-7-17-6-3-4-8-20(17)23/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308176 (1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4O2S/c23-17-9-11-26(12-10-17)18-6-8-21-20(14-18)22(25-24-21)29(27,28)19-7-5-15-3-1-2-4-16(15)13-19/h1-8,13-14,17H,9-12,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308181 ((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308169 ((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...) Show SMILES Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-12-11-16(23)14-26)13-19(20)22(24-25)29(27,28)21-8-4-6-15-5-2-3-7-18(15)21/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308168 ((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308171 ((3R)-1-[1-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-23-11-10-20(28-13-12-19(26)16-28)14-22(23)25(27-29)32(30,31)24-9-5-7-18-6-3-4-8-21(18)24/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50319673 (1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...) Show SMILES Fc1ccc(cc1)-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 Show InChI InChI=1S/C21H27FN4O/c22-18-8-6-17(7-9-18)20-11-10-19(16-24-20)25-21(27)23-12-2-5-15-26-13-3-1-4-14-26/h6-11,16H,1-5,12-15H2,(H2,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308173 ((3R)-1-[2-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-24(31(29,30)23-9-5-7-17-6-3-4-8-20(17)23)21-14-19(10-11-22(21)26-28)27-13-12-18(25)15-27/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308172 ((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...) Show SMILES Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-22(29(27,28)21-8-4-6-15-5-2-3-7-18(15)21)19-13-17(9-10-20(19)24-25)26-12-11-16(23)14-26/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	54.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308174 ((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-25(32(30,31)24-9-5-7-18-6-3-4-8-21(18)24)22-14-20(10-11-23(22)27-29)28-13-12-19(26)16-28/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308178 (1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2c(Cl)cccc12 Show InChI InChI=1S/C22H21ClN4O2S/c23-19-5-1-4-17-16(19)3-2-6-21(17)30(28,29)22-18-13-15(7-8-20(18)25-26-22)27-11-9-14(24)10-12-27/h1-8,13-14H,9-12,24H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308183 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...) Show SMILES NC1CN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C20H18N4O2S/c21-14-11-24(12-14)15-8-9-18-17(10-15)20(23-22-18)27(25,26)19-7-3-5-13-4-1-2-6-16(13)19/h1-10,14H,11-12,21H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308175 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c23-16-10-12-26(13-11-16)17-8-9-20-19(14-17)22(25-24-20)29(27,28)21-7-3-5-15-4-1-2-6-18(15)21/h1-9,14,16H,10-13,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308169 ((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...) Show SMILES Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-12-11-16(23)14-26)13-19(20)22(24-25)29(27,28)21-8-4-6-15-5-2-3-7-18(15)21/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308170 ((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-22-11-10-19(27-13-12-18(25)15-27)14-21(22)24(26-28)31(29,30)23-9-5-7-17-6-3-4-8-20(17)23/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308174 ((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-25(32(30,31)24-9-5-7-18-6-3-4-8-21(18)24)22-14-20(10-11-23(22)27-29)28-13-12-19(26)16-28/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308167 ((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308179 (1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H19ClN4O2S/c19-12-2-1-3-15(10-12)26(24,25)18-16-11-14(4-5-17(16)21-22-18)23-8-6-13(20)7-9-23/h1-5,10-11,13H,6-9,20H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	442	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308172 ((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...) Show SMILES Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-22(29(27,28)21-8-4-6-15-5-2-3-7-18(15)21)19-13-17(9-10-20(19)24-25)26-12-11-16(23)14-26/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	455	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308177 (1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES Cc1ccc(c2ccccc12)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C23H24N4O2S/c1-15-6-9-22(19-5-3-2-4-18(15)19)30(28,29)23-20-14-17(7-8-21(20)25-26-23)27-12-10-16(24)11-13-27/h2-9,14,16H,10-13,24H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	493	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308168 ((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308176 (1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4O2S/c23-17-9-11-26(12-10-17)18-6-8-21-20(14-18)22(25-24-21)29(27,28)19-7-5-15-3-1-2-4-16(15)13-19/h1-8,13-14,17H,9-12,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to 5HT1D receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to dopamine D2 receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308173 ((3R)-1-[2-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-24(31(29,30)23-9-5-7-17-6-3-4-8-20(17)23)21-14-19(10-11-22(21)26-28)27-13-12-18(25)15-27/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308171 ((3R)-1-[1-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-23-11-10-20(28-13-12-19(26)16-28)14-22(23)25(27-29)32(30,31)24-9-5-7-18-6-3-4-8-21(18)24/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50319673 (1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...) Show SMILES Fc1ccc(cc1)-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 Show InChI InChI=1S/C21H27FN4O/c22-18-8-6-17(7-9-18)20-11-10-19(16-24-20)25-21(27)23-12-2-5-15-26-13-3-1-4-14-26/h6-11,16H,1-5,12-15H2,(H2,23,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Binding affinity to 5HT4 receptor				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to 5HT1B receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308180 (1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C21H26N4O2S/c1-14(2)15-3-6-18(7-4-15)28(26,27)21-19-13-17(5-8-20(19)23-24-21)25-11-9-16(22)10-12-25/h3-8,13-14,16H,9-12,22H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to alpha2A adrenergic receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1 (Homo sapiens (Human))	BDBM50545573 (CHEMBL4635883 | US11530193, Example 54) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human CAMK1A using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1G (Homo sapiens (Human))	BDBM50545573 (CHEMBL4635883 | US11530193, Example 54) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human CAMK1G using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1 (Homo sapiens (Human))	BDBM50545576 (CHEMBL4640712 | US11530193, Example 50) Show SMILES CC(C)(C#N)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(c1)C(C)(C)C#N |r| Show InChI InChI=1S/C24H30N8O/c1-23(2,13-25)15-8-16(24(3,4)14-26)10-18(9-15)30-21-19(20(28)33)11-29-22(31-21)32-7-5-6-17(27)12-32/h8-11,17H,5-7,12,27H2,1-4H3,(H2,28,33)(H,29,30,31)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human CAMK1A using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM78940 (METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...) Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1B (Homo sapiens (Human))	BDBM50545573 (CHEMBL4635883 | US11530193, Example 54) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human CAMK1B using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50249319 (2-(2-aminoethylamino)-4-(3-(trifluoromethyl)phenyl...) Show SMILES NCCNc1ncc(C(N)=O)c(Nc2cccc(c2)C(F)(F)F)n1 Show InChI InChI=1S/C14H15F3N6O/c15-14(16,17)8-2-1-3-9(6-8)22-12-10(11(19)24)7-21-13(23-12)20-5-4-18/h1-3,6-7H,4-5,18H2,(H2,19,24)(H2,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM50545573 (CHEMBL4635883 | US11530193, Example 54) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM50545576 (CHEMBL4640712 | US11530193, Example 50) Show SMILES CC(C)(C#N)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(c1)C(C)(C)C#N |r| Show InChI InChI=1S/C24H30N8O/c1-23(2,13-25)15-8-16(24(3,4)14-26)10-18(9-15)30-21-19(20(28)33)11-29-22(31-21)32-7-5-6-17(27)12-32/h8-11,17H,5-7,12,27H2,1-4H3,(H2,28,33)(H,29,30,31)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured afte...				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM50545573 (CHEMBL4635883 | US11530193, Example 54) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human CAMK1D using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay				J Med Chem 63: 6784-6801 (2020) Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 160 total )  |  Next  |  Last  >>

Jump to: