BindingDB PrimarySearch

Found 8 hits with Last Name = 'landergren' and Initial = 'mr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395319 (CHEMBL2164018) Show SMILES CCCCCC1CC(=O)c2cc(Br)cc(Br)c2O1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395320 (CHEMBL2164016) Show SMILES CCCCC[C@H]1CC(=O)c2cc(Cl)cc(Br)c2O1 \|r\| Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395314 (CHEMBL2164014) Show SMILES CCCCCC1CC(=O)c2cc(Cl)cc(Br)c2O1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395321 (CHEMBL2164015) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395315 (CHEMBL2164009) Show SMILES CCCCCc1cc(=O)c2cc(Cl)cc(Br)c2o1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395318 (CHEMBL2164019) Show SMILES CCCCCC1CC(=O)c2cc(C)cc(C)c2O1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395316 (CHEMBL2164005) Show SMILES Clc1cc(Br)c2OC(CCc3ccccc3)CC(=O)c2c1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50395317 (CHEMBL2164003) Show SMILES CCCC1CC(=O)c2cc(Cl)cc(Br)c2O1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assay				J Med Chem 55: 7104-13 (2012) Article DOI: 10.1021/jm3005288 BindingDB Entry DOI: 10.7270/Q2VT1T6N
University of Gothenburg Curated by ChEMBL					More data for this Ligand-Target Pair