Found 109 hits with Last Name = 'lapointe' and Initial = 'p' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444488
(CHEMBL3092613)Show SMILES CC(C)(C)CN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C27H29F3N4O3/c1-26(2,3)17-34-15-13-21-18(16-34)6-4-8-23(21)36-24-22(7-5-14-31-24)33-25(35)32-19-9-11-20(12-10-19)37-27(28,29)30/h4-12,14H,13,15-17H2,1-3H3,(H2,32,33,35) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444487
(CHEMBL3092631)Show SMILES CC(C)(C)CN1CCC(CC1)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C29H33F3N4O3/c1-28(2,3)19-36-17-14-20(15-18-36)23-7-4-5-9-25(23)38-26-24(8-6-16-33-26)35-27(37)34-21-10-12-22(13-11-21)39-29(30,31)32/h4-13,16,20H,14-15,17-19H2,1-3H3,(H2,34,35,37) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444486
(CHEMBL3091475)Show SMILES CC(C)(C)CN1Cc2cccc(Oc3ncccc3NC(=O)Nc3ccc(OC(F)(F)F)cc3)c2C1 Show InChI InChI=1S/C26H27F3N4O3/c1-25(2,3)16-33-14-17-6-4-8-22(20(17)15-33)35-23-21(7-5-13-30-23)32-24(34)31-18-9-11-19(12-10-18)36-26(27,28)29/h4-13H,14-16H2,1-3H3,(H2,31,32,34) | PDB
UniProtKB/SwissProt
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| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444485
(CHEMBL3092620)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(Cc4ccccc4)CCc23)cc1 Show InChI InChI=1S/C29H25F3N4O3/c30-29(31,32)39-23-13-11-22(12-14-23)34-28(37)35-25-9-5-16-33-27(25)38-26-10-4-8-21-19-36(17-15-24(21)26)18-20-6-2-1-3-7-20/h1-14,16H,15,17-19H2,(H2,34,35,37) | PDB
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PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444484
(CHEMBL3092629)Show SMILES CN1Cc2cccc(Oc3ncccc3NC(=O)Nc3ccc(OC(F)(F)F)cc3)c2C1C(C)(C)C Show InChI InChI=1S/C26H27F3N4O3/c1-25(2,3)22-21-16(15-33(22)4)7-5-9-20(21)35-23-19(8-6-14-30-23)32-24(34)31-17-10-12-18(13-11-17)36-26(27,28)29/h5-14,22H,15H2,1-4H3,(H2,31,32,34) | PDB
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| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444483
(CHEMBL3092614)Show SMILES CC(C)CN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H27F3N4O3/c1-17(2)15-33-14-12-21-18(16-33)5-3-7-23(21)35-24-22(6-4-13-30-24)32-25(34)31-19-8-10-20(11-9-19)36-26(27,28)29/h3-11,13,17H,12,14-16H2,1-2H3,(H2,31,32,34) | PDB
UniProtKB/SwissProt
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| Article
PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444482
(CHEMBL3092628)Show SMILES CC(C)CN1Cc2cccc(Oc3ncccc3NC(=O)Nc3ccc(OC(F)(F)F)cc3)c2C1 Show InChI InChI=1S/C25H25F3N4O3/c1-16(2)13-32-14-17-5-3-7-22(20(17)15-32)34-23-21(6-4-12-29-23)31-24(33)30-18-8-10-19(11-9-18)35-25(26,27)28/h3-12,16H,13-15H2,1-2H3,(H2,30,31,33) | PDB
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| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444481
(CHEMBL3092633)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2ccccc2C2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C31H29F3N4O3/c32-31(33,34)41-25-14-12-24(13-15-25)36-30(39)37-27-10-6-18-35-29(27)40-28-11-5-4-9-26(28)23-16-19-38(20-17-23)21-22-7-2-1-3-8-22/h1-15,18,23H,16-17,19-21H2,(H2,36,37,39) | PDB
UniProtKB/SwissProt
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PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444480
(CHEMBL3092632)Show SMILES CC(C)CN1CCC(CC1)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C28H31F3N4O3/c1-19(2)18-35-16-13-20(14-17-35)23-6-3-4-8-25(23)37-26-24(7-5-15-32-26)34-27(36)33-21-9-11-22(12-10-21)38-28(29,30)31/h3-12,15,19-20H,13-14,16-18H2,1-2H3,(H2,33,34,36) | PDB
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| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444479
(CHEMBL3092619)Show SMILES CC(C)(C)CCN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C28H31F3N4O3/c1-27(2,3)14-17-35-16-13-22-19(18-35)6-4-8-24(22)37-25-23(7-5-15-32-25)34-26(36)33-20-9-11-21(12-10-20)38-28(29,30)31/h4-12,15H,13-14,16-18H2,1-3H3,(H2,33,34,36) | PDB
UniProtKB/SwissProt
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| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444478
(CHEMBL3092625)Show SMILES Oc1ccccc1CN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C29H25F3N4O4/c30-29(31,32)40-22-12-10-21(11-13-22)34-28(38)35-24-7-4-15-33-27(24)39-26-9-3-6-19-17-36(16-14-23(19)26)18-20-5-1-2-8-25(20)37/h1-13,15,37H,14,16-18H2,(H2,34,35,38) | PDB
UniProtKB/SwissProt
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UniChem
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| Article
PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444477
(CHEMBL3092621)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(CCc4ccccc4)CCc23)cc1 Show InChI InChI=1S/C30H27F3N4O3/c31-30(32,33)40-24-13-11-23(12-14-24)35-29(38)36-26-9-5-17-34-28(26)39-27-10-4-8-22-20-37(19-16-25(22)27)18-15-21-6-2-1-3-7-21/h1-14,17H,15-16,18-20H2,(H2,35,36,38) | PDB
UniProtKB/SwissProt
antibodypedia
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PC sid
UniChem
Similars
| Article
PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444476
(CHEMBL3092617)Show SMILES CC(C)N1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H25F3N4O3/c1-16(2)32-14-12-20-17(15-32)5-3-7-22(20)34-23-21(6-4-13-29-23)31-24(33)30-18-8-10-19(11-9-18)35-25(26,27)28/h3-11,13,16H,12,14-15H2,1-2H3,(H2,30,31,33) | PDB
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444475
(CHEMBL3092615)Show SMILES CCCN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H25F3N4O3/c1-2-14-32-15-12-20-17(16-32)5-3-7-22(20)34-23-21(6-4-13-29-23)31-24(33)30-18-8-10-19(11-9-18)35-25(26,27)28/h3-11,13H,2,12,14-16H2,1H3,(H2,30,31,33) | PDB
UniProtKB/SwissProt
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PC sid
UniChem
Similars
| Article
PubMed
| 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444474
(CHEMBL3092624)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(Cc4ccncc4)CCc23)cc1 Show InChI InChI=1S/C28H24F3N5O3/c29-28(30,31)39-22-8-6-21(7-9-22)34-27(37)35-24-4-2-13-33-26(24)38-25-5-1-3-20-18-36(16-12-23(20)25)17-19-10-14-32-15-11-19/h1-11,13-15H,12,16-18H2,(H2,34,35,37) | PDB
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| 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444473
(CHEMBL3092622)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(Cc4ccccn4)CCc23)cc1 Show InChI InChI=1S/C28H24F3N5O3/c29-28(30,31)39-22-11-9-20(10-12-22)34-27(37)35-24-7-4-15-33-26(24)38-25-8-3-5-19-17-36(16-13-23(19)25)18-21-6-1-2-14-32-21/h1-12,14-15H,13,16-18H2,(H2,34,35,37) | PDB
UniProtKB/SwissProt
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UniChem
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PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444472
(CHEMBL3092623)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(Cc4cccnc4)CCc23)cc1 Show InChI InChI=1S/C28H24F3N5O3/c29-28(30,31)39-22-10-8-21(9-11-22)34-27(37)35-24-6-3-14-33-26(24)38-25-7-1-5-20-18-36(15-12-23(20)25)17-19-4-2-13-32-16-19/h1-11,13-14,16H,12,15,17-18H2,(H2,34,35,37) | PDB
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| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444471
(CHEMBL3092616)Show SMILES CCN1CCc2c(C1)cccc2Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C24H23F3N4O3/c1-2-31-14-12-19-16(15-31)5-3-7-21(19)33-22-20(6-4-13-28-22)30-23(32)29-17-8-10-18(11-9-17)34-24(25,26)27/h3-11,13H,2,12,14-15H2,1H3,(H2,29,30,32) | PDB
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| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444470
(CHEMBL3092626)Show SMILES Oc1cccc(CN2CCc3c(C2)cccc3Oc2ncccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C29H25F3N4O4/c30-29(31,32)40-23-11-9-21(10-12-23)34-28(38)35-25-7-3-14-33-27(25)39-26-8-2-5-20-18-36(15-13-24(20)26)17-19-4-1-6-22(37)16-19/h1-12,14,16,37H,13,15,17-18H2,(H2,34,35,38) | PDB
UniProtKB/SwissProt
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UniChem
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| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444469
(CHEMBL3092618)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CNCCc23)cc1 Show InChI InChI=1S/C22H19F3N4O3/c23-22(24,25)32-16-8-6-15(7-9-16)28-21(30)29-18-4-2-11-27-20(18)31-19-5-1-3-14-13-26-12-10-17(14)19/h1-9,11,26H,10,12-13H2,(H2,28,29,30) | PDB
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| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444468
(CHEMBL3092627)Show SMILES Oc1ccc(CN2CCc3c(C2)cccc3Oc2ncccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C29H25F3N4O4/c30-29(31,32)40-23-12-8-21(9-13-23)34-28(38)35-25-4-2-15-33-27(25)39-26-5-1-3-20-18-36(16-14-24(20)26)17-19-6-10-22(37)11-7-19/h1-13,15,37H,14,16-18H2,(H2,34,35,38) | PDB
UniProtKB/SwissProt
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| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50444467
(CHEMBL3092630)Show SMILES CN1Cc2cccc(Oc3ncccc3NC(=O)Nc3ccc(OC(F)(F)F)cc3)c2C1 Show InChI InChI=1S/C22H19F3N4O3/c1-29-12-14-4-2-6-19(17(14)13-29)31-20-18(5-3-11-26-20)28-21(30)27-15-7-9-16(10-8-15)32-22(23,24)25/h2-11H,12-13H2,1H3,(H2,27,28,30) | PDB
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| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor transfected in HEK293 cells after 1 hr by scintillation counting method |
Bioorg Med Chem Lett 23: 6825-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.009
BindingDB Entry DOI: 10.7270/Q2TQ630T |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176023
(US10047103, 56 | US9688695, 56)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCCOCC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H23N5O5S2/c1-29-15-8-18(32-12-14-13-34-21(24-14)27-4-3-6-31-7-5-27)16-10-20(33-19(16)9-15)17-11-28-22(25-17)35-23(26-28)30-2/h8-11,13H,3-7,12H2,1-2H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176082
(US10047103, 115 | US9688695, 115)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C3CCC(F)(F)CC3)cc(OC)cc2o1 Show InChI InChI=1S/C24H22F2N4O4S2/c1-31-15-7-18(33-11-14-12-35-21(27-14)13-3-5-24(25,26)6-4-13)16-9-20(34-19(16)8-15)17-10-30-22(28-17)36-23(29-30)32-2/h7-10,12-13H,3-6,11H2,1-2H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176053
(US10047103, 86 | US9688695, 86)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C(F)(F)F)N3CCOCC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H20F3N5O5S2/c1-32-12-7-16(35-11-15-19(23(24,25)26)37-20(28-15)30-3-5-34-6-4-30)13-9-18(36-17(13)8-12)14-10-31-21(27-14)38-22(29-31)33-2/h7-10H,3-6,11H2,1-2H3 | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM175970
(US10047103, 3 | US9605024, Example 3 | US9688695, ...)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccccc3)cc(OC)cc2o1 Show InChI InChI=1S/C24H18N4O4S2/c1-29-16-8-19(31-12-15-13-33-22(25-15)14-6-4-3-5-7-14)17-10-21(32-20(17)9-16)18-11-28-23(26-18)34-24(27-28)30-2/h3-11,13H,12H2,1-2H3 | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176039
(US10047103, 72 | US9688695, 72)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(N)=O)cc(OC)cc2o1 Show InChI InChI=1S/C25H19N5O5S2/c1-32-16-7-19(34-11-15-12-36-23(27-15)14-5-3-13(4-6-14)22(26)31)17-9-21(35-20(17)8-16)18-10-30-24(28-18)37-25(29-30)33-2/h3-10,12H,11H2,1-2H3,(H2,26,31) | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM50600788
(CHEMBL5206065)Show SMILES CCCc1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1 | UniProtKB/SwissProt
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| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176007
(US10047103, 40 | US9688695, 40)Show SMILES CNC(=O)c1ccc(cc1)-c1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1 Show InChI InChI=1S/C26H21N5O5S2/c1-27-23(32)14-4-6-15(7-5-14)24-28-16(13-37-24)12-35-20-8-17(33-2)9-21-18(20)10-22(36-21)19-11-31-25(29-19)38-26(30-31)34-3/h4-11,13H,12H2,1-3H3,(H,27,32) | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176003
(US10047103, 36 | US9688695, 36)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(=O)N(C)C)cc(OC)cc2o1 Show InChI InChI=1S/C27H23N5O5S2/c1-31(2)25(33)16-7-5-15(6-8-16)24-28-17(14-38-24)13-36-21-9-18(34-3)10-22-19(21)11-23(37-22)20-12-32-26(29-20)39-27(30-32)35-4/h5-12,14H,13H2,1-4H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176061
(US10047103, 94 | US9688695, 94)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)N3CCOCC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H23N5O5S2/c1-13-17(25-21(34-13)27-4-6-31-7-5-27)12-32-18-8-14(29-2)9-19-15(18)10-20(33-19)16-11-28-22(24-16)35-23(26-28)30-3/h8-11H,4-7,12H2,1-3H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM50600792
(CHEMBL5189522)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3ccnc(n3)N3CCOCC3)cc(OC)cc2o1 | UniProtKB/SwissProt
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| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM175988
(US10047103, 21 | US9688695, 21)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCCCC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H23N5O4S2/c1-29-15-8-18(31-12-14-13-33-21(24-14)27-6-4-3-5-7-27)16-10-20(32-19(16)9-15)17-11-28-22(25-17)34-23(26-28)30-2/h8-11,13H,3-7,12H2,1-2H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM286418
(US9518064, Example 34)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3ccc(OC)nc3)cc(OC)cc2o1 Show InChI InChI=1S/C27H22N4O5S/c1-32-19-10-22(35-15-16-5-4-6-17(9-16)18-7-8-25(33-2)28-13-18)20-12-24(36-23(20)11-19)21-14-31-26(29-21)37-27(30-31)34-3/h4-14H,15H2,1-3H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM286424
(US9518064, Example 40)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3ccc(OC)cn3)cc(OC)cc2o1 Show InChI InChI=1S/C27H22N4O5S/c1-32-18-7-8-21(28-13-18)17-6-4-5-16(9-17)15-35-23-10-19(33-2)11-24-20(23)12-25(36-24)22-14-31-26(29-22)37-27(30-31)34-3/h4-14H,15H2,1-3H3 | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM286419
(US9518064, Example 35)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3ccc(cn3)C#N)cc(OC)cc2o1 Show InChI InChI=1S/C27H19N5O4S/c1-33-19-9-23(35-15-16-4-3-5-18(8-16)21-7-6-17(12-28)13-29-21)20-11-25(36-24(20)10-19)22-14-32-26(30-22)37-27(31-32)34-2/h3-11,13-14H,15H2,1-2H3 | UniProtKB/SwissProt
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176019
(US10047103, 52 | US9688695, 52)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C(C)C)cc(OC)cc2o1 Show InChI InChI=1S/C21H20N4O4S2/c1-11(2)19-22-12(10-30-19)9-28-16-5-13(26-3)6-17-14(16)7-18(29-17)15-8-25-20(23-15)31-21(24-25)27-4/h5-8,10-11H,9H2,1-4H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176026
(US10047103, 59 | US9688695, 59)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C3CCSCC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H22N4O4S3/c1-28-15-7-18(30-11-14-12-33-21(24-14)13-3-5-32-6-4-13)16-9-20(31-19(16)8-15)17-10-27-22(25-17)34-23(26-27)29-2/h7-10,12-13H,3-6,11H2,1-2H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176258
(US10047103, 291 | US9688695, 291)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(=O)N3CCC(F)(F)C3)cc(OC)cc2o1 Show InChI InChI=1S/C29H23F2N5O5S2/c1-38-19-9-22(20-11-24(41-23(20)10-19)21-12-36-27(33-21)43-28(34-36)39-2)40-13-18-14-42-25(32-18)16-3-5-17(6-4-16)26(37)35-8-7-29(30,31)15-35/h3-6,9-12,14H,7-8,13,15H2,1-2H3 | UniProtKB/SwissProt
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| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM286427
(US9518064, Example 43)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3ccc(cn3)C(F)(F)F)cc(OC)cc2o1 Show InChI InChI=1S/C27H19F3N4O4S/c1-35-18-9-22(19-11-24(38-23(19)10-18)21-13-34-25(32-21)39-26(33-34)36-2)37-14-15-4-3-5-16(8-15)20-7-6-17(12-31-20)27(28,29)30/h3-13H,14H2,1-2H3 | UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM175990
(US10047103, 23 | US9688695, 23)Show SMILES CCc1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1 Show InChI InChI=1S/C20H18N4O4S2/c1-4-18-21-11(10-29-18)9-27-15-5-12(25-2)6-16-13(15)7-17(28-16)14-8-24-19(22-14)30-20(23-24)26-3/h5-8,10H,4,9H2,1-3H3 | UniProtKB/SwissProt
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GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM175972
(US10047103, 5 | US9688695, 5)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCOCC3)cc(OC)cc2o1 Show InChI InChI=1S/C22H21N5O5S2/c1-28-14-7-17(31-11-13-12-33-20(23-13)26-3-5-30-6-4-26)15-9-19(32-18(15)8-14)16-10-27-21(24-16)34-22(25-27)29-2/h7-10,12H,3-6,11H2,1-2H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176063
(US10047103, 96 | US9688695, 96)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3coc(n3)N3CCOCC3)cc(OC)cc2o1 Show InChI InChI=1S/C22H21N5O6S/c1-28-14-7-17(31-11-13-12-32-20(23-13)26-3-5-30-6-4-26)15-9-19(33-18(15)8-14)16-10-27-21(24-16)34-22(25-27)29-2/h7-10,12H,3-6,11H2,1-2H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM50600791
(CHEMBL5177223)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(n3)N3CCOCC3)cc(OC)cc2o1 | UniProtKB/SwissProt
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GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176059
(US10047103, 92 | US9688695, 92)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CC4CCC(C3)O4)cc(OC)cc2o1 Show InChI InChI=1S/C24H23N5O5S2/c1-30-16-5-19(32-11-13-12-35-22(25-13)28-8-14-3-4-15(9-28)33-14)17-7-21(34-20(17)6-16)18-10-29-23(26-18)36-24(27-29)31-2/h5-7,10,12,14-15H,3-4,8-9,11H2,1-2H3 | UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM176268
(US10047103, 301 | US9688695, 301)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(=O)N3CCCC3)cc(OC)cc2o1 Show InChI InChI=1S/C29H25N5O5S2/c1-36-20-11-23(21-13-25(39-24(21)12-20)22-14-34-28(31-22)41-29(32-34)37-2)38-15-19-16-40-26(30-19)17-5-7-18(8-6-17)27(35)33-9-3-4-10-33/h5-8,11-14,16H,3-4,9-10,15H2,1-2H3 | UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM50600784
(CHEMBL5184586)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cc(OC)cc(c3)C(F)(F)F)cc(OC)cc2o1 | UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM286431
(US9518064, Example 47)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnc(OC)nc3)cc(OC)cc2o1 Show InChI InChI=1S/C26H21N5O5S/c1-32-18-8-21(35-14-15-5-4-6-16(7-15)17-11-27-24(33-2)28-12-17)19-10-23(36-22(19)9-18)20-13-31-25(29-20)37-26(30-31)34-3/h4-13H,14H2,1-3H3 | UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM175989
(US10047103, 22 | US9688695, 22)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCN(C)CC3)cc(OC)cc2o1 Show InChI InChI=1S/C23H24N6O4S2/c1-27-4-6-28(7-5-27)21-24-14(13-34-21)12-32-18-8-15(30-2)9-19-16(18)10-20(33-19)17-11-29-22(25-17)35-23(26-29)31-3/h8-11,13H,4-7,12H2,1-3H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
Proteinase-activated receptor 4
(Homo sapiens (Human)) | BDBM50600790
(CHEMBL5171201)Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)N3CCOCC3)cc(OC)cc2o1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00359
BindingDB Entry DOI: 10.7270/Q2VH5SWM |
More data for this
Ligand-Target Pair | |
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