Found 20 hits with Last Name = 'leborgne' and Initial = 'm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Squalene synthase
(Rattus norvegicus) | BDBM50031839
(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#6](P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C13H26O6P2/c1-11(2)7-6-9-12(3)8-4-5-10-13(20(14,15)16)21(17,18)19/h7-8,13H,4-6,9-10H2,1-3H3,(H2,14,15,16)(H2,17,18,19)/b12-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50059875
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287113
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(19-35(32,33)34)26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-16,24-25H,8-9,11,13,17-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,22-16?/t24?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287113
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(19-35(32,33)34)26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-16,24-25H,8-9,11,13,17-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,22-16?/t24?,25-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287115
((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6]=[#6](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(35(32,33)34)19-26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22,25H,8-9,11,13,16,18-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,24-17?/t22?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50059860
(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6](=O)P([#8])([#8])=O Show InChI InChI=1S/C15H27O4P/c1-12(2)7-5-8-13(3)9-6-10-14(4)11-15(16)20(17,18)19/h7,9,14H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)/b13-9+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287115
((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6]=[#6](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(35(32,33)34)19-26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22,25H,8-9,11,13,16,18-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,24-17?/t22?,25-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287116
(((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C25H38NO4P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(31(28,29)30)25(27)26-19-18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22H,8-9,11,13,16,18-19H2,1-4H3,(H,26,27)(H2,28,29,30)/b21-12+,24-17? | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287118
((R)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287118
((R)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50059875
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287117
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])P([#8])([#8])=O |w:16.17| Show InChI InChI=1S/C27H40NO6P/c1-20(2)11-9-12-21(3)13-10-14-22(4)17-18-25(35(31,32)33)26(29)28-24(27(30)34-5)19-23-15-7-6-8-16-23/h6-8,11,13,15-16,18,22,24H,9-10,12,14,17,19H2,1-5H3,(H,28,29)(H2,31,32,33)/b21-13+,25-18?/t22?,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50059860
(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6](=O)P([#8])([#8])=O Show InChI InChI=1S/C15H27O4P/c1-12(2)7-5-8-13(3)9-6-10-14(4)11-15(16)20(17,18)19/h7,9,14H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)/b13-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287114
((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C27H37NO5/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-23(26(30)31)25(29)28-24(27(32)33)18-22-14-6-5-7-15-22/h5-7,10,12,14-16,23-24H,8-9,11,13,17-18H2,1-4H3,(H,28,29)(H,30,31)(H,32,33)/b20-12+,21-16+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Squalene synthase
(Rattus norvegicus) | BDBM50287112
((S)-3-Phenyl-2-[(4E,8E)-5,9,13-trimethyl-2-(2-phos...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C28H42NO6P/c1-21(2)10-8-11-22(3)12-9-13-23(4)16-17-25(18-19-36(33,34)35)27(30)29-26(28(31)32)20-24-14-6-5-7-15-24/h5-7,10,12,14-16,25-26H,8-9,11,13,17-20H2,1-4H3,(H,29,30)(H,31,32)(H2,33,34,35)/b22-12+,23-16?/t25?,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of squalene synthase from rat liver microsomes |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287112
((S)-3-Phenyl-2-[(4E,8E)-5,9,13-trimethyl-2-(2-phos...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C28H42NO6P/c1-21(2)10-8-11-22(3)12-9-13-23(4)16-17-25(18-19-36(33,34)35)27(30)29-26(28(31)32)20-24-14-6-5-7-15-24/h5-7,10,12,14-16,25-26H,8-9,11,13,17-20H2,1-4H3,(H,29,30)(H,31,32)(H2,33,34,35)/b22-12+,23-16?/t25?,26-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287116
(((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C25H38NO4P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(31(28,29)30)25(27)26-19-18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22H,8-9,11,13,16,18-19H2,1-4H3,(H,26,27)(H2,28,29,30)/b21-12+,24-17? | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287114
((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C27H37NO5/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-23(26(30)31)25(29)28-24(27(32)33)18-22-14-6-5-7-15-22/h5-7,10,12,14-16,23-24H,8-9,11,13,17-18H2,1-4H3,(H,28,29)(H,30,31)(H,32,33)/b20-12+,21-16+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50031839
(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#6](P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C13H26O6P2/c1-11(2)7-6-9-12(3)8-4-5-10-13(20(14,15)16)21(17,18)19/h7-8,13H,4-6,9-10H2,1-3H3,(H2,14,15,16)(H2,17,18,19)/b12-8+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of farnesyl protein transferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50287117
((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])P([#8])([#8])=O |w:16.17| Show InChI InChI=1S/C27H40NO6P/c1-20(2)11-9-12-21(3)13-10-14-22(4)17-18-25(35(31,32)33)26(29)28-24(27(30)34-5)19-23-15-7-6-8-16-23/h6-8,11,13,15-16,18,22,24H,9-10,12,14,17,19H2,1-5H3,(H,28,29)(H2,31,32,33)/b21-13+,25-18?/t22?,24-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Farnesyltransferase from bovine brain |
Bioorg Med Chem Lett 6: 1291-1296 (1996)
Article DOI: 10.1016/0960-894X(96)00238-7
BindingDB Entry DOI: 10.7270/Q2ZC82TQ |
More data for this
Ligand-Target Pair | |
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