Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359981 (CHEMBL1927770) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359982 (CHEMBL1927771) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174413 (2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359981 (CHEMBL1927770) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 321 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Fibroblast growth factor receptor 3 | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174413 (2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Fibroblast growth factor receptor 3 | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359983 (CHEMBL1927769) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 559 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50004227 (5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174412 (9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359984 (CHEMBL1927768) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 607 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359982 (CHEMBL1927771) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359985 (CHEMBL1927772) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359986 (CHEMBL1927625) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 793 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174412 (9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359981 (CHEMBL1927770) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 811 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359982 (CHEMBL1927771) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174410 (1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174410 (1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Fibroblast growth factor receptor 3 | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359984 (CHEMBL1927768) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174411 (CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174407 (CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174411 (CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174407 (CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174408 (1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359981 (CHEMBL1927770) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of TPR-fused MET-mediated mouse BA/F3 cell proliferation after 48 hrs by cell titre blue based spectrophotometry | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359985 (CHEMBL1927772) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359987 (CHEMBL1927778) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50359984 (CHEMBL1927768) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6216 Curated by ChEMBL | Assay Description Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow... | Eur J Med Chem 47: 239-54 (2012) Article DOI: 10.1016/j.ejmech.2011.10.051 BindingDB Entry DOI: 10.7270/Q2XK8FZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174409 (9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50174409 (9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113 Curated by ChEMBL | Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus | J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR | |||||||||||
More data for this Ligand-Target Pair |