Compile Data Set for Download or QSAR

Found 76 hits with Last Name = 'nemeth' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074439 (1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-p...) Show SMILES COc1cc(Br)c(c(OC)c1)-n1ccc2c(C)cc(C)nc12 |(12.47,-15.06,;10.97,-14.75,;10.48,-13.3,;11.5,-12.14,;11.01,-10.69,;12.02,-9.53,;9.5,-10.37,;8.48,-11.53,;6.98,-11.21,;5.96,-12.35,;8.97,-12.98,;9.03,-8.92,;9.92,-7.66,;9.01,-6.42,;7.54,-6.91,;6.21,-6.14,;6.21,-4.6,;4.88,-6.91,;4.88,-8.45,;3.55,-9.22,;6.21,-9.22,;7.56,-8.45,)| Show InChI InChI=1S/C17H17BrN2O2/c1-10-7-11(2)19-17-13(10)5-6-20(17)16-14(18)8-12(21-3)9-15(16)22-4/h5-9H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074411 ((2-Bromo-4,6-dimethoxy-phenyl)-(4,6-dimethyl-pyrim...) Show SMILES CCN(c1nc(C)cc(C)n1)c1c(Br)cc(OC)cc1OC Show InChI InChI=1S/C16H20BrN3O2/c1-6-20(16-18-10(2)7-11(3)19-16)15-13(17)8-12(21-4)9-14(15)22-5/h7-9H,6H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074372 ((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...) Show SMILES CCN(c1nc(C)cc(n1)N1CCOCC1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H27BrN4O/c1-5-25(18-7-6-16(14(2)3)13-17(18)21)20-22-15(4)12-19(23-20)24-8-10-26-11-9-24/h6-7,12-14H,5,8-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074435 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholi...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(cc(C)nc12)N1CCOCC1 Show InChI InChI=1S/C21H24BrN3O/c1-14(2)16-4-5-19(18(22)13-16)25-7-6-17-20(12-15(3)23-21(17)25)24-8-10-26-11-9-24/h4-7,12-14H,8-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074420 (1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-p...) Show SMILES COc1cc(Br)c(c(OC)c1)-n1cc(C#N)c2c(C)cc(C)nc12 |(12.47,-15.06,;10.97,-14.75,;10.48,-13.3,;11.5,-12.14,;11.01,-10.69,;12.02,-9.53,;9.5,-10.37,;8.48,-11.53,;6.98,-11.21,;5.96,-12.35,;8.97,-12.98,;9.03,-8.92,;9.92,-7.66,;9.01,-6.42,;9.48,-4.95,;9.95,-3.48,;7.54,-6.91,;6.21,-6.14,;6.21,-4.6,;4.88,-6.91,;4.88,-8.45,;3.55,-9.22,;6.21,-9.22,;7.56,-8.45,)| Show InChI InChI=1S/C18H16BrN3O2/c1-10-5-11(2)21-18-16(10)12(8-20)9-22(18)17-14(19)6-13(23-3)7-15(17)24-4/h5-7,9H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074425 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(cc(C)nc12)-c1ccccc1 Show InChI InChI=1S/C24H20BrN3/c1-15(2)18-9-10-22(21(25)12-18)28-14-19(13-26)23-20(11-16(3)27-24(23)28)17-7-5-4-6-8-17/h4-12,14-15H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074429 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(cc(C)nc12)-c1ccccc1 Show InChI InChI=1S/C23H21BrN2/c1-15(2)18-9-10-22(21(24)14-18)26-12-11-19-20(13-16(3)25-23(19)26)17-7-5-4-6-8-17/h4-15H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074351 ((4,6-Dimethyl-pyrimidin-2-yl)-ethyl-(2-iodo-4-isop...) Show SMILES CCN(c1nc(C)cc(C)n1)c1ccc(cc1I)C(C)C Show InChI InChI=1S/C17H22IN3/c1-6-21(17-19-12(4)9-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074353 ((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-m...) Show SMILES CCN(c1nc(C)nc(n1)N1CCOCC1)c1c(Br)cc(OC)cc1OC Show InChI InChI=1S/C18H24BrN5O3/c1-5-24(16-14(19)10-13(25-3)11-15(16)26-4)18-21-12(2)20-17(22-18)23-6-8-27-9-7-23/h10-11H,5-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074350 ((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...) Show SMILES CCN(c1nc(C)cc(C)n1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C17H22BrN3/c1-6-21(17-19-12(4)9-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074437 (1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(C)nc12 Show InChI InChI=1S/C18H19BrN2/c1-11(2)14-5-6-17(16(19)10-14)21-8-7-15-12(3)9-13(4)20-18(15)21/h5-11H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074432 ((4,6-Dimethyl-pyrimidin-2-yl)-(2-iodo-4-isopropyl-...) Show SMILES CC(C)c1ccc(N(C)c2nc(C)cc(C)n2)c(I)c1 Show InChI InChI=1S/C16H20IN3/c1-10(2)13-6-7-15(14(17)9-13)20(5)16-18-11(3)8-12(4)19-16/h6-10H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074430 (1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(Cl)cc(C)nc12 Show InChI InChI=1S/C17H16BrClN2/c1-10(2)12-4-5-16(14(18)9-12)21-7-6-13-15(19)8-11(3)20-17(13)21/h4-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074419 (1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(Cl)nc12 Show InChI InChI=1S/C17H16BrClN2/c1-10(2)12-4-5-15(14(18)9-12)21-7-6-13-11(3)8-16(19)20-17(13)21/h4-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074408 ((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...) Show SMILES CC(C)c1ccc(N(C)c2nc(C)cc(C)n2)c(Br)c1 Show InChI InChI=1S/C16H20BrN3/c1-10(2)13-6-7-15(14(17)9-13)20(5)16-18-11(3)8-12(4)19-16/h6-10H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074423 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholi...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(cc(C)nc12)N1CCOCC1 Show InChI InChI=1S/C22H23BrN4O/c1-14(2)16-4-5-19(18(23)11-16)27-13-17(12-24)21-20(10-15(3)25-22(21)27)26-6-8-28-9-7-26/h4-5,10-11,13-14H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074442 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2ccc(C)nc12 Show InChI InChI=1S/C17H17BrN2/c1-11(2)14-6-7-16(15(18)10-14)20-9-8-13-5-4-12(3)19-17(13)20/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	222	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074427 (1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(C)nc12 Show InChI InChI=1S/C19H18BrN3/c1-11(2)14-5-6-17(16(20)8-14)23-10-15(9-21)18-12(3)7-13(4)22-19(18)23/h5-8,10-11H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074417 (1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(Cl)nc12 Show InChI InChI=1S/C18H15BrClN3/c1-10(2)12-4-5-15(14(19)7-12)23-9-13(8-21)17-11(3)6-16(20)22-18(17)23/h4-7,9-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	446	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074440 (1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(Cl)cc(C)nc12 Show InChI InChI=1S/C18H15BrClN3/c1-10(2)12-4-5-16(14(19)7-12)23-9-13(8-21)17-15(20)6-11(3)22-18(17)23/h4-7,9-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	722	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074418 ((2-Bromo-4-isopropyl-phenyl)-(2,6-dimethyl-pyrimid...) Show SMILES CCN(c1cc(C)nc(C)n1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C17H22BrN3/c1-6-21(17-9-12(4)19-13(5)20-17)16-8-7-14(11(2)3)10-15(16)18/h7-11H,6H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074424 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2ccc(C)nc12 Show InChI InChI=1S/C18H16BrN3/c1-11(2)13-5-7-17(16(19)8-13)22-10-14(9-20)15-6-4-12(3)21-18(15)22/h4-8,10-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074433 (1-(4-Isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3...) Show SMILES CC(C)c1ccc(cc1)-n1ccc2c(C)cc(C)nc12 Show InChI InChI=1S/C18H20N2/c1-12(2)15-5-7-16(8-6-15)20-10-9-17-13(3)11-14(4)19-18(17)20/h5-12H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074421 (1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C(O)=O)c2c(C)cc(C)nc12 Show InChI InChI=1S/C19H19BrN2O2/c1-10(2)13-5-6-16(15(20)8-13)22-9-14(19(23)24)17-11(3)7-12(4)21-18(17)22/h5-10H,1-4H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074426 (1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)ccnc12 Show InChI InChI=1S/C17H17BrN2/c1-11(2)13-4-5-16(15(18)10-13)20-9-7-14-12(3)6-8-19-17(14)20/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074441 (1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C(N)=O)c2c(C)cc(C)nc12 Show InChI InChI=1S/C19H20BrN3O/c1-10(2)13-5-6-16(15(20)8-13)23-9-14(18(21)24)17-11(3)7-12(4)22-19(17)23/h5-10H,1-4H3,(H2,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074431 (1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-7-oxy-1H-p...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2ccc(C)[n+]([O-])c12 Show InChI InChI=1S/C18H16BrN3O/c1-11(2)13-5-7-17(16(19)8-13)21-10-14(9-20)15-6-4-12(3)22(23)18(15)21/h4-8,10-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074436 ((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...) Show SMILES CC(C)c1ccc(Nc2nc(C)cc(C)n2)c(Br)c1 Show InChI InChI=1S/C15H18BrN3/c1-9(2)12-5-6-14(13(16)8-12)19-15-17-10(3)7-11(4)18-15/h5-9H,1-4H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074438 (1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)ccnc12 Show InChI InChI=1S/C18H16BrN3/c1-11(2)13-4-5-16(15(19)8-13)22-10-14(9-20)17-12(3)6-7-21-18(17)22/h4-8,10-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074416 (1-(2-Bromo-4-isopropyl-phenyl)-6-hydroxy-4-methyl-...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(=O)[nH]c12 Show InChI InChI=1S/C18H16BrN3O/c1-10(2)12-4-5-15(14(19)7-12)22-9-13(8-20)17-11(3)6-16(23)21-18(17)22/h4-7,9-10H,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074422 (1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1ccc2c(C)cc(nc12)-c1ccccc1 Show InChI InChI=1S/C23H21BrN2/c1-15(2)18-9-10-22(20(24)14-18)26-12-11-19-16(3)13-21(25-23(19)26)17-7-5-4-6-8-17/h4-15H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50074415 (1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1cc(C#N)c2c(C)cc(nc12)-c1ccccc1 Show InChI InChI=1S/C24H20BrN3/c1-15(2)18-9-10-22(20(25)12-18)28-14-19(13-26)23-16(3)11-21(27-24(23)28)17-7-5-4-6-8-17/h4-12,14-15H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity was determined against corticotropin releasing factor receptor 1				J Med Chem 42: 819-32 (1999) Article DOI: 10.1021/jm980223o BindingDB Entry DOI: 10.7270/Q22V2GT5
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29466 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-35) Show SMILES CCC(CC)Nc1nc(C)nc2c(c(C)nn12)-c1cc(F)c(OC)cc1Cl |(2.48,7.45,;.99,7.08,;-.08,8.19,;.35,9.67,;1.85,10.04,;-1.57,7.83,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-2.99,-1.79,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C19H23ClFN5O/c1-6-12(7-2)24-19-23-11(4)22-18-17(10(3)25-26(18)19)13-8-15(21)16(27-5)9-14(13)20/h8-9,12H,6-7H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29452 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-21) Show SMILES COc1cc(C)c(-c2c(C)nn3c(nc(C)nc23)N(CC=C)CC=C)c(OC)c1 |(1.01,-4.1,;-.33,-3.33,;-.33,-1.79,;1.01,-1.02,;1.01,.52,;2.34,1.29,;-.33,1.29,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;-2.59,8.98,;-4.1,8.68,;-5.12,9.84,;-1.66,.52,;-2.99,1.29,;-4.33,.52,;-1.66,-1.02,)| Show InChI InChI=1S/C22H27N5O2/c1-8-10-26(11-9-2)22-24-16(5)23-21-20(15(4)25-27(21)22)19-14(3)12-17(28-6)13-18(19)29-7/h8-9,12-13H,1-2,10-11H2,3-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29468 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-37) Show SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1cc(F)c(OC)cc1Cl |(-2.73,13.03,;-3.19,11.56,;-2.15,10.43,;-2.61,8.96,;-1.57,7.83,;-.08,8.19,;.35,9.67,;1.85,10.04,;2.28,11.52,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-2.99,-1.79,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C20H25ClFN5O3/c1-12-18(14-10-16(22)17(30-5)11-15(14)21)19-23-13(2)24-20(27(19)25-12)26(6-8-28-3)7-9-29-4/h10-11H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29450 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-19) Show SMILES CCN(CC)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(.43,9.59,;-.06,8.13,;-1.57,7.83,;-2.59,8.98,;-4.1,8.68,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C20H27N5O2/c1-8-24(9-2)20-22-14(5)21-19-18(13(4)23-25(19)20)17-12(3)10-15(26-6)11-16(17)27-7/h10-11H,8-9H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29453 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-22) Show SMILES CCCN(CC1CC1)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(-5.12,9.84,;-4.1,8.68,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;.04,11.08,;1.52,10.67,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C23H31N5O2/c1-7-10-27(13-17-8-9-17)23-25-16(4)24-22-21(15(3)26-28(22)23)20-14(2)11-18(29-5)12-19(20)30-6/h11-12,17H,7-10,13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29467 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-36) Show SMILES CCN(CC)c1nc(C)nc2c(c(C)nn12)-c1cc(F)c(OC)cc1Cl |(-2.15,10.43,;-2.61,8.96,;-1.57,7.83,;-.08,8.19,;.35,9.67,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-2.99,-1.79,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C18H21ClFN5O/c1-6-24(7-2)18-22-11(4)21-17-16(10(3)23-25(17)18)12-8-14(20)15(26-5)9-13(12)19/h8-9H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29456 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-25) Show SMILES CCCCN(CC)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(2.43,11.35,;1.94,9.89,;.43,9.59,;-.06,8.13,;-1.57,7.83,;-2.59,8.98,;-4.1,8.68,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C22H31N5O2/c1-8-10-11-26(9-2)22-24-16(5)23-21-20(15(4)25-27(21)22)19-14(3)12-17(28-6)13-18(19)29-7/h12-13H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29457 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-26) Show SMILES CCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(-4.1,8.68,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;2.43,11.35,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C21H29N5O3/c1-8-25(9-10-27-5)21-23-15(4)22-20-19(14(3)24-26(20)21)18-13(2)11-16(28-6)12-17(18)29-7/h11-12H,8-10H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29458 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-27) Show SMILES COCCN(CC1CC1)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(2.43,11.35,;1.94,9.89,;.43,9.59,;-.06,8.13,;-1.57,7.83,;-2.59,8.98,;-4.1,8.68,;-5.55,9.2,;-5.28,7.69,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C23H31N5O3/c1-14-11-18(30-5)12-19(31-6)20(14)21-15(2)26-28-22(21)24-16(3)25-23(28)27(9-10-29-4)13-17-7-8-17/h11-12,17H,7-10,13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29440 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-9) Show SMILES COc1ccc(-c2c(C)nn3c(nc(C)nc23)N(CCC#N)C2CC2)c(C)c1 |(1.01,-4.1,;-.33,-3.33,;-.33,-1.79,;-1.66,-1.02,;-1.66,.52,;-.33,1.29,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;3.43,10.29,;-2.59,8.98,;-3.36,10.32,;-4.13,8.98,;1.01,.52,;2.34,1.29,;1.01,-1.02,)| Show InChI InChI=1S/C21H24N6O/c1-13-12-17(28-4)8-9-18(13)19-14(2)25-27-20(19)23-15(3)24-21(27)26(11-5-10-22)16-6-7-16/h8-9,12,16H,5-7,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29465 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-34) Show SMILES CCC(CC)Nc1nc(C)nc2c(c(C)nn12)-c1cc(F)c(OC)cc1C |(2.48,7.45,;.99,7.08,;-.08,8.19,;.35,9.67,;1.85,10.04,;-1.57,7.83,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-2.99,-1.79,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C20H26FN5O/c1-7-14(8-2)24-20-23-13(5)22-19-18(12(4)25-26(19)20)15-10-16(21)17(27-6)9-11(15)3/h9-10,14H,7-8H2,1-6H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29438 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-7) Show SMILES CCCN(CC1CC1)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C |(-3.11,11.6,;-2.1,10.44,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;.28,11.12,;1.68,10.48,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C22H29N5O/c1-6-11-26(13-17-7-8-17)22-24-16(4)23-21-20(15(3)25-27(21)22)19-10-9-18(28-5)12-14(19)2/h9-10,12,17H,6-8,11,13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29464 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-33) Show SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1cc(C)c(OC)cc1C |(2.28,11.52,;1.85,10.04,;.35,9.67,;-.08,8.19,;-1.57,7.83,;-2.64,8.94,;-2.24,10.43,;-3.33,11.51,;-2.93,13,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-2.99,-1.79,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C22H31N5O3/c1-14-13-19(30-7)15(2)12-18(14)20-16(3)25-27-21(20)23-17(4)24-22(27)26(8-10-28-5)9-11-29-6/h12-13H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29448 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-17) Show SMILES CCCC(C)Nc1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(3.51,6.21,;2.45,7.33,;.95,6.97,;-.06,8.13,;.43,9.59,;-1.57,7.83,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C21H29N5O2/c1-8-9-13(3)22-21-24-15(5)23-20-19(14(4)25-26(20)21)18-12(2)10-16(27-6)11-17(18)28-7/h10-11,13H,8-9H2,1-7H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29439 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-8) Show SMILES CCCN(CCC#N)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C |(-3.11,11.6,;-2.1,10.44,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;3.43,10.29,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C21H26N6O/c1-6-11-26(12-7-10-22)21-24-16(4)23-20-19(15(3)25-27(20)21)18-9-8-17(28-5)13-14(18)2/h8-9,13H,6-7,11-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29437 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-6) Show SMILES CCCCN(CC)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C |(2.43,11.35,;1.94,9.89,;.43,9.59,;-.06,8.13,;-1.57,7.83,;-2.59,8.98,;-2.1,10.44,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C21H29N5O/c1-7-9-12-25(8-2)21-23-16(5)22-20-19(15(4)24-26(20)21)18-11-10-17(27-6)13-14(18)3/h10-11,13H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29460 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-29) Show SMILES CCN(CCC#N)c1nc(C)nc2c(c(C)nn12)-c1c(C)cc(OC)cc1OC |(-2.1,10.44,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;3.43,10.29,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;1.01,.52,;2.34,1.29,;1.01,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;-1.66,-1.02,;-1.66,.52,;-2.99,1.29,;-4.33,.52,)| Show InChI InChI=1S/C21H26N6O2/c1-7-26(10-8-9-22)21-24-15(4)23-20-19(14(3)25-27(20)21)18-13(2)11-16(28-5)12-17(18)29-6/h11-12H,7-8,10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.48	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29436 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-5) Show SMILES CCCN(CCC)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C |(-3.11,11.6,;-2.1,10.44,;-2.59,8.98,;-1.57,7.83,;-.06,8.13,;.43,9.59,;1.94,9.89,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C21H29N5O/c1-7-11-25(12-8-2)21-23-16(5)22-20-19(15(4)24-26(20)21)18-10-9-17(27-6)13-14(18)3/h9-10,13H,7-8,11-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.58	n/a	n/a	n/a	n/a	7.2	23
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
					More data for this Ligand-Target Pair

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