Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'oizumi' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472616 (CHEMBL65325) Show SMILES CN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(7)24(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472618 (CHEMBL303092) Show SMILES CON1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO4S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(24-7)25(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472632 (CHEMBL65140) Show SMILES CC(=O)N1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H29NO4S/c1-13(22)21-9-8-15(26(21,24)25)10-14-11-16(19(2,3)4)18(23)17(12-14)20(5,6)7/h10-12,23H,8-9H2,1-7H3/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472627 (CHEMBL304489) Show SMILES CC(C)(C)c1cc(\C=C2\CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C24H30ClNO3S/c1-23(2,3)20-14-16(15-21(22(20)27)24(4,5)6)13-19-11-12-26(30(19,28)29)18-9-7-17(25)8-10-18/h7-10,13-15,27H,11-12H2,1-6H3/b19-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472623 (CHEMBL294100) Show SMILES CC(C)(C)c1cc(\C=C2\CCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO3S/c1-17(2,3)14-10-12(9-13-7-8-19-23(13,21)22)11-15(16(14)20)18(4,5)6/h9-11,19-20H,7-8H2,1-6H3/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472624 (CHEMBL62439) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C24H30ClNO3S/c1-23(2,3)20-14-16(15-21(22(20)27)24(4,5)6)13-19-11-12-26(30(19,28)29)18-9-7-17(25)8-10-18/h7-10,13-15,27H,11-12H2,1-6H3/b19-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472613 (CHEMBL305076) Show SMILES CCN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H31NO3S/c1-8-21-10-9-15(25(21,23)24)11-14-12-16(19(2,3)4)18(22)17(13-14)20(5,6)7/h11-13,22H,8-10H2,1-7H3/b15-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472605 (CHEMBL64507) Show SMILES CON1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO4S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(24-7)25(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472612 (CHEMBL60496) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(C3CC3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C21H31NO3S/c1-20(2,3)17-12-14(13-18(19(17)23)21(4,5)6)11-16-9-10-22(15-7-8-15)26(16,24)25/h11-13,15,23H,7-10H2,1-6H3/b16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50024714 (2-(4-Carboxymethyl-5-oxo-3-thiophen-2-yl-[1,4]thia...) Show SMILES OC(=O)CN1C(CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1cccs1 Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)11-23-17(18-7-4-10-30-18)13-29-12-16(20(23)26)22-15(21(27)28)9-8-14-5-2-1-3-6-14/h1-7,10,15-17,22H,8-9,11-13H2,(H,24,25)(H,27,28)/t15-,16-,17?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023299 (2-(1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino...) Show SMILES OC(=O)CN1C[C@H](CC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C24H28N2O5/c27-22(28)16-26-15-19(18-9-5-2-6-10-18)12-14-20(23(26)29)25-21(24(30)31)13-11-17-7-3-1-4-8-17/h1-10,19-21,25H,11-16H2,(H,27,28)(H,30,31)/t19-,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023298 (2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1[C@@H](CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)13-25-20(17-9-5-2-6-10-17)15-31-14-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023298 (2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1[C@@H](CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)13-25-20(17-9-5-2-6-10-17)15-31-14-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50024710 (2-(4-Carboxymethyl-5-oxo-2-thiophen-2-yl-[1,4]thia...) Show SMILES OC(=O)CN1C[C@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1cccs1 Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)12-23-11-18(17-7-4-10-29-17)30-13-16(20(23)26)22-15(21(27)28)9-8-14-5-2-1-3-6-14/h1-7,10,15-16,18,22H,8-9,11-13H2,(H,24,25)(H,27,28)/t15-,16-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023296 (2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino...) Show SMILES OC(=O)CN1[C@@H](CCC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C24H28N2O5/c27-22(28)16-26-21(18-10-5-2-6-11-18)13-7-12-19(23(26)29)25-20(24(30)31)15-14-17-8-3-1-4-9-17/h1-6,8-11,19-21,25H,7,12-16H2,(H,27,28)(H,30,31)/t19-,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023295 (2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1C[C@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)14-25-13-20(17-9-5-2-6-10-17)31-15-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023295 (2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1C[C@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)14-25-13-20(17-9-5-2-6-10-17)31-15-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50024713 (2-(4-Carboxymethyl-5-oxo-2-thiophen-3-yl-[1,4]thia...) Show SMILES OC(=O)CN1C[C@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccsc1 Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)11-23-10-18(15-8-9-29-12-15)30-13-17(20(23)26)22-16(21(27)28)7-6-14-4-2-1-3-5-14/h1-5,8-9,12,16-18,22H,6-7,10-11,13H2,(H,24,25)(H,27,28)/t16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023300 (2-(1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino...) Show SMILES OC(=O)CN1C[C@@H](CC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C24H28N2O5/c27-22(28)16-26-15-19(18-9-5-2-6-10-18)12-14-20(23(26)29)25-21(24(30)31)13-11-17-7-3-1-4-8-17/h1-10,19-21,25H,11-16H2,(H,27,28)(H,30,31)/t19-,20+,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50011192 ((R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylamino)-...) Show SMILES CC(NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12?,14?,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50367254 (ENALAPRILAT) Show SMILES C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472615 (CHEMBL64813) Show SMILES CC(C)(C)c1cc(\C=C2/CCCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-7-9-20-24(14,22)23/h10-12,20-21H,7-9H2,1-6H3/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472610 (CHEMBL60725) Show SMILES CN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(7)24(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472622 (CHEMBL291543) Show SMILES CCN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H31NO3S/c1-8-21-10-9-15(25(21,23)24)11-14-12-16(19(2,3)4)18(22)17(13-14)20(5,6)7/h11-13,22H,8-10H2,1-7H3/b15-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472631 (CHEMBL60738) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(O)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO4S/c1-17(2,3)14-10-12(11-15(16(14)20)18(4,5)6)9-13-7-8-19(21)24(13,22)23/h9-11,20-21H,7-8H2,1-6H3/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472619 (CHEMBL62990) Show SMILES CCCN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H33NO3S/c1-8-10-22-11-9-16(26(22,24)25)12-15-13-17(20(2,3)4)19(23)18(14-15)21(5,6)7/h12-14,23H,8-11H2,1-7H3/b16-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472625 (CHEMBL62920) Show SMILES CCCN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H33NO3S/c1-8-10-22-11-9-16(26(22,24)25)12-15-13-17(20(2,3)4)19(23)18(14-15)21(5,6)7/h12-14,23H,8-11H2,1-7H3/b16-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023302 (2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino...) Show SMILES OC(=O)CN1[C@H](CCC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C24H28N2O5/c27-22(28)16-26-21(18-10-5-2-6-11-18)13-7-12-19(23(26)29)25-20(24(30)31)15-14-17-8-3-1-4-9-17/h1-6,8-11,19-21,25H,7,12-16H2,(H,27,28)(H,30,31)/t19-,20-,21+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472603 (CHEMBL65330) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(C(=O)NO)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C19H28N2O5S/c1-18(2,3)14-10-12(11-15(16(14)22)19(4,5)6)9-13-7-8-21(17(23)20-24)27(13,25)26/h9-11,22,24H,7-8H2,1-6H3,(H,20,23)/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472609 (CHEMBL64585) Show SMILES CC(C)(C)c1cc(\C=C2/CCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO3S/c1-17(2,3)14-10-12(9-13-7-8-19-23(13,21)22)11-15(16(14)20)18(4,5)6/h9-11,19-20H,7-8H2,1-6H3/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023303 (2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1C[C@@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)14-25-13-20(17-9-5-2-6-10-17)31-15-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023303 (2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1C[C@@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)14-25-13-20(17-9-5-2-6-10-17)31-15-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472604 (CHEBI:35847 | CP-66,248 | Tenidap) Show SMILES NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12 Show InChI InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50024712 (2-(4-Carboxymethyl-5-oxo-2-thiophen-2-yl-[1,4]thia...) Show SMILES OC(=O)CN1C[C@@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1cccs1 Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)12-23-11-18(17-7-4-10-29-17)30-13-16(20(23)26)22-15(21(27)28)9-8-14-5-2-1-3-6-14/h1-7,10,15-16,18,22H,8-9,11-13H2,(H,24,25)(H,27,28)/t15-,16-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023301 (2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1[C@H](CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)13-25-20(17-9-5-2-6-10-17)15-31-14-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50023301 (2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...) Show SMILES OC(=O)CN1[C@H](CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26N2O5S/c26-21(27)13-25-20(17-9-5-2-6-10-17)15-31-14-19(22(25)28)24-18(23(29)30)12-11-16-7-3-1-4-8-16/h1-10,18-20,24H,11-15H2,(H,26,27)(H,29,30)/t18-,19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate				J Med Chem 31: 422-8 (1988) BindingDB Entry DOI: 10.7270/Q2S75GWH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50024711 (2-(4-Carboxymethyl-5-oxo-2-thiophen-3-yl-[1,4]thia...) Show SMILES OC(=O)CN1C[C@@H](SC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccsc1 Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)11-23-10-18(15-8-9-29-12-15)30-13-17(20(23)26)22-16(21(27)28)7-6-14-4-2-1-3-5-14/h1-5,8-9,12,16-18,22H,6-7,10-11,13H2,(H,24,25)(H,27,28)/t16-,17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate				J Med Chem 30: 1984-91 (1987) BindingDB Entry DOI: 10.7270/Q2Q52NMJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472608 (CHEMBL60793) Show SMILES CON(C)C(=O)N1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H32N2O5S/c1-20(2,3)16-12-14(13-17(18(16)24)21(4,5)6)11-15-9-10-23(29(15,26)27)19(25)22(7)28-8/h11-13,24H,9-10H2,1-8H3/b15-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472607 (CHEMBL302441) Show SMILES CN1OCC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO4S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-24-20(7)25(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472621 (CHEMBL62632) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(CCO)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C20H31NO4S/c1-19(2,3)16-12-14(13-17(18(16)23)20(4,5)6)11-15-7-8-21(9-10-22)26(15,24)25/h11-13,22-23H,7-10H2,1-6H3/b15-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472620 (CHEMBL64759) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3cccnc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H30N2O3S/c1-22(2,3)19-13-16(14-20(21(19)26)23(4,5)6)12-18-9-11-25(29(18,27)28)17-8-7-10-24-15-17/h7-8,10,12-15,26H,9,11H2,1-6H3/b18-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472611 (CHEMBL293689) Show SMILES CC(C)N1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H33NO3S/c1-14(2)22-10-9-16(26(22,24)25)11-15-12-17(20(3,4)5)19(23)18(13-15)21(6,7)8/h11-14,23H,9-10H2,1-8H3/b16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472614 (CHEMBL64182) Show SMILES CN(C)CCN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C22H36N2O3S/c1-21(2,3)18-14-16(15-19(20(18)25)22(4,5)6)13-17-9-10-24(28(17,26)27)12-11-23(7)8/h13-15,25H,9-12H2,1-8H3/b17-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472617 (CHEMBL61731) Show SMILES CC(C)CN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C22H35NO3S/c1-15(2)14-23-10-9-17(27(23,25)26)11-16-12-18(21(3,4)5)20(24)19(13-16)22(6,7)8/h11-13,15,24H,9-10,14H2,1-8H3/b17-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472628 (CHEMBL62723) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3ccncc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H30N2O3S/c1-22(2,3)19-14-16(15-20(21(19)26)23(4,5)6)13-18-9-12-25(29(18,27)28)17-7-10-24-11-8-17/h7-8,10-11,13-15,26H,9,12H2,1-6H3/b18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472629 (CHEMBL62874) Show SMILES CC(C)(C)c1cc(\C=C2\CCN(O)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO4S/c1-17(2,3)14-10-12(11-15(16(14)20)18(4,5)6)9-13-7-8-19(21)24(13,22)23/h9-11,20-21H,7-8H2,1-6H3/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472626 (CHEMBL302155) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3ccccn3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H30N2O3S/c1-22(2,3)18-14-16(15-19(21(18)26)23(4,5)6)13-17-10-12-25(29(17,27)28)20-9-7-8-11-24-20/h7-9,11,13-15,26H,10,12H2,1-6H3/b17-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472606 (CHEMBL303365) Show SMILES CC(C)(C)c1cc(\C=C2/CCN(CC(O)=O)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C20H29NO5S/c1-19(2,3)15-10-13(11-16(18(15)24)20(4,5)6)9-14-7-8-21(12-17(22)23)27(14,25)26/h9-11,24H,7-8,12H2,1-6H3,(H,22,23)/b14-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50472630 (CHEMBL64891) Show SMILES CC(C)(C)c1cc(\C=C2\CCN(c3ccccn3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H30N2O3S/c1-22(2,3)18-14-16(15-19(21(18)26)23(4,5)6)13-17-10-12-25(29(17,27)28)20-9-7-8-11-24-20/h7-9,11,13-15,26H,10,12H2,1-6H3/b17-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.				J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8
					More data for this Ligand-Target Pair