BindingDB PrimarySearch

Found 183 hits with Last Name = 'parsons' and Initial = 'cg'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	10.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine \| 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine \| 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	20.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296674 ((E)-1-Adamantan-1-yl-3-quinolin-3-yl-propenone \| C...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296665 (Adamantan-1-yl-[2-(6-morpholin-4-yl-2-pyridin-3-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	24.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	27.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM82270 (CAS_7424-00-2 \| DL-4-Chlorophenylalanine \| PCP) Show SMILES NC(Cc1ccc(Cl)cc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	42.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231755 (6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...) Show SMILES CC1(C)CCc2nc(ccc2C1=O)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50000663 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	53.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50296665 (Adamantan-1-yl-[2-(6-morpholin-4-yl-2-pyridin-3-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Binding affinity to human GluR1 by FLIPR assay				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296677 (Adamantan-1-yl-(2-quinolin-3-yl-cyclopropyl)-metha...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231728 (5-methoxy-2-phenylethynyl-5,6,7,8-tetrahydro-quino...) Show SMILES COC1CCCc2nc(ccc12)C#Cc1ccccc1 \|w:2.1\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM82270 (CAS_7424-00-2 \| DL-4-Chlorophenylalanine \| PCP) Show SMILES NC(Cc1ccc(Cl)cc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231738 (7,7-dimethyl-2-pyridin-2-ylethynyl-7,8-dihydro-6H-...) Show SMILES CC1(C)CC(=O)c2ccc(nc2C1)C#Cc1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296676 ((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	294	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296679 (Adamantan-1-yl-[2-(6-methoxy-pyridin-3-yl)-cyclopr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	304	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 1 (RAT)	BDBM50296675 ((E)-1-Adamantan-1-yl-3-(2,3-dihydro-benzo[1,4]diox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	641	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one \| CH...) Show SMILES O=C1CCCc2nc(ccc12)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50296674 ((E)-1-Adamantan-1-yl-3-quinolin-3-yl-propenone \| C...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	807	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation counting				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50044140 (2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone \| ...) Show SMILES CNC1(CCCCC1=O)c1ccccc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231751 (6-phenylethynyl-nicotinic acid methyl ester \| CHEM...) Show SMILES COC(=O)c1ccc(nc1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231753 (2-phenylethynyl-5,6,7,8-tetrahydro-quinoline \| CHE...) Show SMILES C1CCc2nc(ccc2C1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231721 (2-pyridin-2-ylethynyl-7,8-dihydro-6H-quinolin-5-on...) Show SMILES O=C1CCCc2nc(ccc12)C#Cc1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine \| CHEMBL807 \| EN3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50044140 (2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone \| ...) Show SMILES CNC1(CCCCC1=O)c1ccccc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231747 ((R)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...) Show SMILES O[C@@H]1CCCc2nc(ccc12)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50296676 ((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation counting				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296673 ((E)-4,4-Dimethyl-1-quinolin-3-yl-pent-1-en-3-one \|...) Show SMILES CC(C)(C)C(=O)\C=C\c1cnc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50296675 ((E)-1-Adamantan-1-yl-3-(2,3-dihydro-benzo[1,4]diox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation counting				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296678 (Adamantan-1-yl-(2-pyridin-3-yl-cyclopropyl)-methan...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231719 (2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-ol \|...) Show SMILES OC1CCCc2nc(ccc12)C#Cc1ccccc1 \|w:1.0\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296668 (3-(2-chloro-6-methylquinolin-3-yl)-1-phenylprop-2-...) Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccccc3)cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50231759 ((S)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...) Show SMILES O[C@H]1CCCc2nc(ccc12)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGluR5				J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296666 (3-(2-chloro-6-methylquinolin-3-yl)-1-(thiophen-2-y...) Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3cccs3)cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50033369 (AMANTADINE \| CHEMBL660 \| SYMADINE \| SYMMETREL) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP K_i Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
Merz Co. GmbH & Co. Curated by PDSP K_i Database					More data for this Ligand-Target Pair

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