BindingDB PrimarySearch

Found 17 hits with Last Name = 'pettus' and Initial = 'tr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin \| C...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50126186 (2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assay				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin \| C...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50157547 (2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4...) Show SMILES Oc1ccc(cc1O)-c1cc(=O)c2ccc(O)c(O)c2o1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HEK293 cells by flashplate assay				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50157547 (2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4...) Show SMILES Oc1ccc(cc1O)-c1cc(=O)c2ccc(O)c(O)c2o1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50157547 (2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4...) Show SMILES Oc1ccc(cc1O)-c1cc(=O)c2ccc(O)c(O)c2o1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396097 (CHEMBL2170856) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human U937 cells by telomeric repeat amplification protocol				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human U937 cells				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396098 (CHEMBL2170857) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396098 (CHEMBL2170857) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396098 (CHEMBL2170857) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human K562 cells by modified telomeric repeat amplification protocol				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50126186 (2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50126186 (2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396097 (CHEMBL2170856) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50396097 (CHEMBL2170856) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...				J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair