Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21995 (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0900 | -56.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21992 (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.310 | -53.7 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21996 (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.430 | -52.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21994 (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.520 | -52.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21987 (6-[(6-fluoroquinolin-4-yl)methyl]-5-{[(3R)-3-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.810 | -51.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21998 (6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | -50.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21997 (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | -49.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21993 (6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.20 | -48.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21985 (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 4.80 | -47.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21991 (5-{[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]carbonyl}...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 29 | -42.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21990 (5-(azetidin-1-ylcarbonyl)-3-methyl-6-{[2-(methylam...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 59 | -40.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21988 (N,N,3-trimethyl-2,4-dioxo-1-(propan-2-yl)-6-{[2-(t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 117 | -39.2 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21989 (3-{[3-methyl-2,4-dioxo-1-(propan-2-yl)-6-{[2-(trif...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >190 | >-38.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
