BindingDB PrimarySearch

Found 617 hits with Last Name = 'pu' and Initial = 'x'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid \| (2S,4...) Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.663	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 4 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Binding affinity to rat cloned KA1 receptor				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid \| (2S,4...) Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	5.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	6.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252050 ((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM85807 (Beta-PEA \| CAS_60-12-8 \| NSC_6054) Show SMILES OCCc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	12.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Binding affinity to rat cloned KA2 receptor				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid \| (2S,4...) Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	32.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM29135 (CHEMBL11608 \| cid_5610 \| p-Tyramine \| tyramine) Show SMILES NCCc1ccc(O)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 4 (Rattus norvegicus)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Binding affinity to rat cloned KA1 receptor				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252048 ((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells				J Med Chem 51: 4085-92 (2008) Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	57.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	75.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344388 (2-((3-chlorophenyl)ethynyl)-6-isopropyl-7,8-dihydr...) Show SMILES CC(C)N1CCc2nc(ccc2C1=O)C#Cc1cccc(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50251893 ((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
Lundbeck Research USA, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344379 (2-((3-chlorophenyl)ethynyl)-6-methyl-7,8-dihydro-1...) Show SMILES CN1CCc2nc(ccc2C1=O)C#Cc1cccc(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat cloned iGluR7				J Med Chem 51: 4085-92 (2008) Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
Lundbeck Research USA, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
Lundbeck Research USA, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	422	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM22872 (1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...) Show SMILES CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	493	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	494	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344386 (6-isopropyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-nap...) Show SMILES CC(C)N1CCc2nc(ccc2C1=O)C#Cc1cccc(C)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252052 ((2S,4R)-2-amino-4-(3-(ethylamino)-3-oxopropyl)pent...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	641	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344398 (6-cyclopentyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-n...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344412 (6-cyclohexyl-2-(thiophen-2-ylethynyl)-7,8-dihydro-...) Show SMILES O=C1N(CCc2nc(ccc12)C#Cc1cccs1)C1CCCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344417 (6-Methyl-2-phenylethynyl-7,8-dihydro-6H-1,6-naphth...) Show SMILES CN1CCc2nc(ccc2C1=O)C#Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344419 (6-methyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-naphth...) Show SMILES CN1CCc2nc(ccc2C1=O)C#Cc1cccc(C)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344396 (6-cyclopentyl-2-(phenylethynyl)-7,8-dihydro-1,6-na...) Show SMILES O=C1N(CCc2nc(ccc12)C#Cc1ccccc1)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50252046 ((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells				J Med Chem 51: 4085-92 (2008) Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM50252048 ((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine \| 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344384 (6-isopropyl-2-(phenylethynyl)-7,8-dihydro-1,6-naph...) Show SMILES CC(C)N1CCc2nc(ccc2C1=O)C#Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus)	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344393 (6-cyclopentyl-2-(pyridin-2-ylethynyl)-7,8-dihydro-...) Show SMILES O=C1N(CCc2nc(ccc12)C#Cc1ccccn1)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344392 (6-isopropyl-2-(thiophen-2-ylethynyl)-7,8-dihydro-1...) Show SMILES CC(C)N1CCc2nc(ccc2C1=O)C#Cc1cccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50344383 (6-methyl-2-(thiophen-2-ylethynyl)-7,8-dihydro-1,6-...) Show SMILES CN1CCc2nc(ccc2C1=O)C#Cc1cccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrs				Bioorg Med Chem Lett 21: 3407-10 (2011) Article DOI: 10.1016/j.bmcl.2011.03.103 BindingDB Entry DOI: 10.7270/Q2HQ4075
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair

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