Compile Data Set for Download or QSAR

Found 163 hits with Last Name = 'saitoh' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM150291 (US8987242, 105) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(cc1)N1CCO[C@H]([C@@H](O)C(=O)Nc2ccc(cc2)C(N)=N)C1=O Show InChI InChI=1S/C26H26N4O6S/c1-37(34,35)21-5-3-2-4-20(21)16-8-12-19(13-9-16)30-14-15-36-23(26(30)33)22(31)25(32)29-18-10-6-17(7-11-18)24(27)28/h2-13,22-23,31H,14-15H2,1H3,(H3,27,28)(H,29,32)/t22-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150295 (US8987242, aa144) Show SMILES OC([C@H]1OCCN(C1=O)c1ccc(F)c(c1)C(=O)N1CCOCC1)C(=O)Nc1ccc2C(=N)NCc2c1 Show InChI InChI=1S/C25H26FN5O6/c26-19-4-2-16(12-18(19)24(34)30-5-8-36-9-6-30)31-7-10-37-21(25(31)35)20(32)23(33)29-15-1-3-17-14(11-15)13-28-22(17)27/h1-4,11-12,20-21,32H,5-10,13H2,(H2,27,28)(H,29,33)/t20?,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150289 (US8987242, 15) Show SMILES NC(=N)c1ccc(NC(=O)[C@H](O)[C@H]2OCCN(C2=O)c2ccc(cc2)C2CCCCC2)cc1 Show InChI InChI=1S/C25H30N4O4/c26-23(27)18-6-10-19(11-7-18)28-24(31)21(30)22-25(32)29(14-15-33-22)20-12-8-17(9-13-20)16-4-2-1-3-5-16/h6-13,16,21-22,30H,1-5,14-15H2,(H3,26,27)(H,28,31)/t21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150285 (US8987242, 50) Show SMILES NC(=N)c1ccc(NC(=O)[C@H](O)[C@H]2OCCN(C2=O)c2cccc(NC(=O)CO)c2)cc1 |r| Show InChI InChI=1S/C21H23N5O6/c22-19(23)12-4-6-13(7-5-12)25-20(30)17(29)18-21(31)26(8-9-32-18)15-3-1-2-14(10-15)24-16(28)11-27/h1-7,10,17-18,27,29H,8-9,11H2,(H3,22,23)(H,24,28)(H,25,30)/t17-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150286 (US8987242, 62) Show SMILES Cc1ccc(cc1)N1CCO[C@H]([C@@H](O)C(=O)Nc2ccc3c(N)nccc3c2)C1=O |r| Show InChI InChI=1S/C22H22N4O4/c1-13-2-5-16(6-3-13)26-10-11-30-19(22(26)29)18(27)21(28)25-15-4-7-17-14(12-15)8-9-24-20(17)23/h2-9,12,18-19,27H,10-11H2,1H3,(H2,23,24)(H,25,28)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150293 (US8987242, 114) Show SMILES Cc1ccc(cc1)N1CCCO[C@H]([C@@H](O)C(=O)Nc2ccc(cc2)C(N)=N)C1=O Show InChI InChI=1S/C21H24N4O4/c1-13-3-9-16(10-4-13)25-11-2-12-29-18(21(25)28)17(26)20(27)24-15-7-5-14(6-8-15)19(22)23/h3-10,17-18,26H,2,11-12H2,1H3,(H3,22,23)(H,24,27)/t17-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150290 (US8987242, 2) Show SMILES Cc1ccc(cc1)N1CCOC(C(O)C(=O)Nc2ccc(cc2)C(N)=N)C1=O Show InChI InChI=1S/C20H22N4O4/c1-12-2-8-15(9-3-12)24-10-11-28-17(20(24)27)16(25)19(26)23-14-6-4-13(5-7-14)18(21)22/h2-9,16-17,25H,10-11H2,1H3,(H3,21,22)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM150288 (US8987242, 1) Show SMILES Cc1ccc(cc1)N1CCOC(C(O)C(=O)Nc2ccc3c(N)nccc3c2)C1=O Show InChI InChI=1S/C22H22N4O4/c1-13-2-5-16(6-3-13)26-10-11-30-19(22(26)29)18(27)21(28)25-15-4-7-17-14(12-15)8-9-24-20(17)23/h2-9,12,18-19,27H,10-11H2,1H3,(H2,23,24)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412264 (US10399945, Example 3 | US10399945, Example 9 | US...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H31N5O2/c1-18-14-24(27(20-10-6-5-7-11-20)34-26(18)21-16-31-19(2)32-17-21)33-29(37)35-28-22-12-8-9-13-23(22)30(3,4)15-25(28)36/h5-14,16-17,25,28,36H,15H2,1-4H3,(H2,33,35,37)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412265 (US10399945, Example 10 | US10399945, Example 4 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H31N5O2/c1-18-14-23(26(19-10-6-5-7-11-19)32-25(18)20-16-30-34(4)17-20)31-28(36)33-27-21-12-8-9-13-22(21)29(2,3)15-24(27)35/h5-14,16-17,24,27,35H,15H2,1-4H3,(H2,31,33,36)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412266 (US10399945, Example 18 | US10399945, Example 5 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cn[nH]c1)-c1ccccc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412267 (US10399945, Example 6 | US10669239, Compound 20 | ...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(O)nc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H30N4O3/c1-18-15-23(27(19-9-5-4-6-10-19)33-26(18)20-13-14-25(36)31-17-20)32-29(37)34-28-21-11-7-8-12-22(21)30(2,3)16-24(28)35/h4-15,17,24,28,35H,16H2,1-3H3,(H,31,36)(H2,32,34,37)/t24-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412263 (US10399945, Example 2 | US10399945, Example 7 | US...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H27N3O2/c1-16-13-20(22(26-15-16)17-9-5-4-6-10-17)27-24(30)28-23-18-11-7-8-12-19(18)25(2,3)14-21(23)29/h4-13,15,21,23,29H,14H2,1-3H3,(H2,27,28,30)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412272 (US10399945, Example 11 | US10927079, Compound 11) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cncc(c1)C(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C31H29F3N4O2/c1-18-13-24(36-29(40)38-28-22-11-7-8-12-23(22)30(2,3)15-25(28)39)27(19-9-5-4-6-10-19)37-26(18)20-14-21(17-35-16-20)31(32,33)34/h4-14,16-17,25,28,39H,15H2,1-3H3,(H2,36,38,40)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412273 (US10399945, Example 12 | US10927079, Compound 12) Show SMILES Cc1ccc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C31H32N4O2/c1-19-16-25(28(21-10-6-5-7-11-21)34-27(19)22-15-14-20(2)32-18-22)33-30(37)35-29-23-12-8-9-13-24(23)31(3,4)17-26(29)36/h5-16,18,26,29,36H,17H2,1-4H3,(H2,33,35,37)/t26-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412274 (US10399945, Example 13) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(nc1)C#C)-c1ccccc1 |r| Show InChI InChI=1S/C32H30N4O2/c1-5-23-16-15-22(19-33-23)28-20(2)17-26(29(35-28)21-11-7-6-8-12-21)34-31(38)36-30-24-13-9-10-14-25(24)32(3,4)18-27(30)37/h1,6-17,19,27,30,37H,18H2,2-4H3,(H2,34,36,38)/t27-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412275 (US10399945, Example 14 | US10927079, Compound 14) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(nc1)S(C)(=O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C31H32N4O4S/c1-19-16-24(33-30(37)35-29-22-12-8-9-13-23(22)31(2,3)17-25(29)36)28(20-10-6-5-7-11-20)34-27(19)21-14-15-26(32-18-21)40(4,38)39/h5-16,18,25,29,36H,17H2,1-4H3,(H2,33,35,37)/t25-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412276 (US10399945, Example 15 | US10927079, Compound 15) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C30H28F3N5O2/c1-17-13-22(36-28(40)38-26-20-11-7-8-12-21(20)29(2,3)14-23(26)39)25(18-9-5-4-6-10-18)37-24(17)19-15-34-27(35-16-19)30(31,32)33/h4-13,15-16,23,26,39H,14H2,1-3H3,(H2,36,38,40)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412269 (US10399945, Example 8 | US10669239, Compound 8 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1CO)-c1ccccc1 |r| Show InChI InChI=1S/C26H29N3O3/c1-16-13-20(23(27-21(16)15-30)17-9-5-4-6-10-17)28-25(32)29-24-18-11-7-8-12-19(18)26(2,3)14-22(24)31/h4-13,22,24,30-31H,14-15H2,1-3H3,(H2,28,29,32)/t22-,24-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412278 (US10399945, Example 17 | US10669239, Compound 17 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccnc(c1)C(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C31H29F3N4O2/c1-18-15-23(36-29(40)38-28-21-11-7-8-12-22(21)30(2,3)17-24(28)39)27(19-9-5-4-6-10-19)37-26(18)20-13-14-35-25(16-20)31(32,33)34/h4-16,24,28,39H,17H2,1-3H3,(H2,36,38,40)/t24-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412266 (US10399945, Example 18 | US10399945, Example 5 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cn[nH]c1)-c1ccccc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412280 (US10399945, Example 19 | US10669239, Compound 19 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(O)nc1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29N5O3/c1-17-13-22(25(18-9-5-4-6-10-18)33-24(17)19-15-30-27(36)31-16-19)32-28(37)34-26-20-11-7-8-12-21(20)29(2,3)14-23(26)35/h4-13,15-16,23,26,35H,14H2,1-3H3,(H,30,31,36)(H2,32,34,37)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412281 (US10399945, Example 20) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(O)nc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H30N4O3/c1-18-15-23(27(19-9-5-4-6-10-19)33-26(18)20-13-14-25(36)31-17-20)32-29(37)34-28-21-11-7-8-12-22(21)30(2,3)16-24(28)35/h4-15,17,24,28,35H,16H2,1-3H3,(H,31,36)(H2,32,34,37)/t24-,28?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412264 (US10399945, Example 3 | US10399945, Example 9 | US...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H31N5O2/c1-18-14-24(27(20-10-6-5-7-11-20)34-26(18)21-16-31-19(2)32-17-21)33-29(37)35-28-22-12-8-9-13-23(22)30(3,4)15-25(28)36/h5-14,16-17,25,28,36H,15H2,1-4H3,(H2,33,35,37)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412265 (US10399945, Example 10 | US10399945, Example 4 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H31N5O2/c1-18-14-23(26(19-10-6-5-7-11-19)32-25(18)20-16-30-34(4)17-20)31-28(36)33-27-21-12-8-9-13-22(21)29(2,3)15-24(27)35/h5-14,16-17,24,27,35H,15H2,1-4H3,(H2,31,33,36)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412262 (US10399945, Example 1 | US10669239, Compound 1 | U...) Show SMILES CC1(C)C[C@@H](O)[C@H](NC(=O)Nc2cccnc2-c2ccccc2)c2ccccc12 |r| Show InChI InChI=1S/C24H25N3O2/c1-24(2)15-20(28)22(17-11-6-7-12-18(17)24)27-23(29)26-19-13-8-14-25-21(19)16-9-4-3-5-10-16/h3-14,20,22,28H,15H2,1-2H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412263 (US10399945, Example 2 | US10399945, Example 7 | US...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H27N3O2/c1-16-13-20(22(26-15-16)17-9-5-4-6-10-17)27-24(30)28-23-18-11-7-8-12-19(18)25(2,3)14-21(23)29/h4-13,15,21,23,29H,14H2,1-3H3,(H2,27,28,30)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412277 (US10399945, Example 16 | US10669239, Compound 16 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(cc1)C#N)-c1ccccc1 |r| Show InChI InChI=1S/C32H30N4O2/c1-20-17-26(34-31(38)36-30-24-11-7-8-12-25(24)32(2,3)18-27(30)37)29(22-9-5-4-6-10-22)35-28(20)23-15-13-21(19-33)14-16-23/h4-17,27,30,37H,18H2,1-3H3,(H2,34,36,38)/t27-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412282 (US10399945, Example 21) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(C)(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C33H37N5O2/c1-20-16-25(36-31(40)38-29-23-14-10-11-15-24(23)33(5,6)17-26(29)39)28(21-12-8-7-9-13-21)37-27(20)22-18-34-30(35-19-22)32(2,3)4/h7-16,18-19,26,29,39H,17H2,1-6H3,(H2,36,38,40)/t26-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412283 (US10399945, Example 22 | US10669239, Compound 22 |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-10-9-17(26)12-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412284 (US10399945, Example 23 | US10669239, Compound 23 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c(nc1C(N)=O)-c1ccccc1 |r| Show InChI InChI=1S/C26H27BrN4O3/c1-14-11-19(22(30-21(14)24(28)33)15-7-5-4-6-8-15)29-25(34)31-23-17-10-9-16(27)12-18(17)26(2,3)13-20(23)32/h4-12,20,23,32H,13H2,1-3H3,(H2,28,33)(H2,29,31,34)/t20-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412285 (US10399945, Example 24 | US10669239, Compound 24 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1C(N)=O)-c1ccccc1 |r| Show InChI InChI=1S/C26H28N4O3/c1-15-13-19(22(29-21(15)24(27)32)16-9-5-4-6-10-16)28-25(33)30-23-17-11-7-8-12-18(17)26(2,3)14-20(23)31/h4-13,20,23,31H,14H2,1-3H3,(H2,27,32)(H2,28,30,33)/t20-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412286 (US10399945, Example 25 | US10669239, Compound 25 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1C(=O)NCC(C)(C)O)-c1ccccc1 |r| Show InChI InChI=1S/C30H36N4O4/c1-18-15-22(25(19-11-7-6-8-12-19)33-24(18)27(36)31-17-30(4,5)38)32-28(37)34-26-20-13-9-10-14-21(20)29(2,3)16-23(26)35/h6-15,23,26,35,38H,16-17H2,1-5H3,(H,31,36)(H2,32,34,37)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412287 (US10399945, Example 26 | US10669239, Compound 26 |...) Show SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1 |r| Show InChI InChI=1S/C24H31N3O3/c1-15-12-19(21(25-14-15)16-8-10-30-11-9-16)26-23(29)27-22-17-6-4-5-7-18(17)24(2,3)13-20(22)28/h4-7,12,14,16,20,22,28H,8-11,13H2,1-3H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412289 (US10399945, Example 28 | US10669239, Compound 28 |...) Show SMILES Cc1ncc(cn1)-c1nc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C |r| Show InChI InChI=1S/C29H35N5O3/c1-17-13-23(26(19-9-11-37-12-10-19)33-25(17)20-15-30-18(2)31-16-20)32-28(36)34-27-21-7-5-6-8-22(21)29(3,4)14-24(27)35/h5-8,13,15-16,19,24,27,35H,9-12,14H2,1-4H3,(H2,32,34,36)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412290 (US10399945, Example 29 | US10669239, Compound 29 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnn(C)c1)C1CCOCC1 |r| Show InChI InChI=1S/C28H35N5O3/c1-17-13-22(25(18-9-11-36-12-10-18)31-24(17)19-15-29-33(4)16-19)30-27(35)32-26-20-7-5-6-8-21(20)28(2,3)14-23(26)34/h5-8,13,15-16,18,23,26,34H,9-12,14H2,1-4H3,(H2,30,32,35)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412291 (US10399945, Example 30 | US10669239, Compound 30 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cn[nH]c1)C1CCOCC1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412292 (US10399945, Example 31 | US10669239, Compound 31 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(O)nc1)C1CCOCC1 |r| Show InChI InChI=1S/C29H34N4O4/c1-17-14-22(26(18-10-12-37-13-11-18)32-25(17)19-8-9-24(35)30-16-19)31-28(36)33-27-20-6-4-5-7-21(20)29(2,3)15-23(27)34/h4-9,14,16,18,23,27,34H,10-13,15H2,1-3H3,(H,30,35)(H2,31,33,36)/t23-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412293 (US10399945, Example 32 | US10927079, Compound 32) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccc(Br)cc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-12-17(26)9-10-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412294 (US10399945, Example 33) Show SMILES COc1ccc2c(c1)[C@@H](NC(=O)Nc1cc(C)cnc1C1CCOCC1)[C@H](O)CC2(C)C |r| Show InChI InChI=1S/C25H33N3O4/c1-15-11-20(22(26-14-15)16-7-9-32-10-8-16)27-24(30)28-23-18-12-17(31-4)5-6-19(18)25(2,3)13-21(23)29/h5-6,11-12,14,16,21,23,29H,7-10,13H2,1-4H3,(H2,27,28,30)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412295 (US10399945, Example 34a | US10669239, Compound 34a...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccc(F)cc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H30FN5O2/c1-17-12-24(27(19-8-6-5-7-9-19)35-26(17)20-15-32-18(2)33-16-20)34-29(38)36-28-22-13-21(31)10-11-23(22)30(3,4)14-25(28)37/h5-13,15-16,25,28,37H,14H2,1-4H3,(H2,34,36,38)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412296 (US10399945, Example 34b | US10669239, Compound 34b) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3ccc(F)cc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H30FN5O2/c1-17-12-24(27(19-8-6-5-7-9-19)35-26(17)20-15-32-18(2)33-16-20)34-29(38)36-28-22-13-21(31)10-11-23(22)30(3,4)14-25(28)37/h5-13,15-16,25,28,37H,14H2,1-4H3,(H2,34,36,38)/t25-,28+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412297 (US10399945, Example 35a | US10669239, Compound 35a...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)ccc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H30FN5O2/c1-17-12-24(27(19-8-6-5-7-9-19)35-26(17)20-15-32-18(2)33-16-20)34-29(38)36-28-22-11-10-21(31)13-23(22)30(3,4)14-25(28)37/h5-13,15-16,25,28,37H,14H2,1-4H3,(H2,34,36,38)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412298 (US10399945, Example 35b | US10669239, Compound 35b) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3cc(F)ccc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H30FN5O2/c1-17-12-24(27(19-8-6-5-7-9-19)35-26(17)20-15-32-18(2)33-16-20)34-29(38)36-28-22-11-10-21(31)13-23(22)30(3,4)14-25(28)37/h5-13,15-16,25,28,37H,14H2,1-4H3,(H2,34,36,38)/t25-,28+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412299 (US10399945, Example 36 | US10669239, Compound 36 |...) Show SMILES CC1(C)C[C@@H](O)[C@H](NC(=O)Nc2cccnc2-c2ccccc2)c2cc(F)c(F)cc12 |r| Show InChI InChI=1S/C24H23F2N3O2/c1-24(2)13-20(30)22(15-11-17(25)18(26)12-16(15)24)29-23(31)28-19-9-6-10-27-21(19)14-7-4-3-5-8-14/h3-12,20,22,30H,13H2,1-2H3,(H2,28,29,31)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412300 (US10399945, Example 37 | US10399945, Example 37a |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H25F2N3O2/c1-14-9-20(22(28-13-14)15-7-5-4-6-8-15)29-24(32)30-23-16-10-18(26)19(27)11-17(16)25(2,3)12-21(23)31/h4-11,13,21,23,31H,12H2,1-3H3,(H2,29,30,32)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412300 (US10399945, Example 37 | US10399945, Example 37a |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H25F2N3O2/c1-14-9-20(22(28-13-14)15-7-5-4-6-8-15)29-24(32)30-23-16-10-18(26)19(27)11-17(16)25(2,3)12-21(23)31/h4-11,13,21,23,31H,12H2,1-3H3,(H2,29,30,32)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412302 (US10399945, Example 37b | US10669239, Compound 37b) Show SMILES Cc1cnc(c(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H25F2N3O2/c1-14-9-20(22(28-13-14)15-7-5-4-6-8-15)29-24(32)30-23-16-10-18(26)19(27)11-17(16)25(2,3)12-21(23)31/h4-11,13,21,23,31H,12H2,1-3H3,(H2,29,30,32)/t21-,23+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412304 (US10399945, Example 39 | US10669239, Compound 39 |...) Show SMILES Cc1ccc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(n1)-c1ccccc1 |r| Show InChI InChI=1S/C25H25F2N3O2/c1-14-9-10-20(22(28-14)15-7-5-4-6-8-15)29-24(32)30-23-16-11-18(26)19(27)12-17(16)25(2,3)13-21(23)31/h4-12,21,23,31H,13H2,1-3H3,(H2,29,30,32)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412305 (US10399945, Example 40 | US10669239, Compound 40) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1C(N)=O)-c1ccccc1 |r| Show InChI InChI=1S/C26H26F2N4O3/c1-13-9-19(22(31-21(13)24(29)34)14-7-5-4-6-8-14)30-25(35)32-23-15-10-17(27)18(28)11-16(15)26(2,3)12-20(23)33/h4-11,20,23,33H,12H2,1-3H3,(H2,29,34)(H2,30,32,35)/t20-,23?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair

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