Found 37 hits with Last Name = 'snyder' and Initial = 'kr' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002186
(CHEMBL440987 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(25-14-17-35-86-48(7)101)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(27-19-37-88-77(84)85)93-67(107)55(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.00420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002182
(CHEMBL415617 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(24-13-16-34-78)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(26-18-36-86-75(83)84)91-65(104)53(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.00670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002185
(CHEMBL438741 | Tyr-Gly-Gly-Phe-Leu-Lys(Ac)-Arg-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-55(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(26-18-36-87-76(82)83)93-67(107)54(25-14-17-35-86-48(7)101)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002181
(CHEMBL266717 | Tyr-Gly-Gly-Phe-Leu-Lys-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-53(24-13-16-34-78)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(25-17-35-85-74(81)82)91-65(104)52(23-12-15-33-77)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002183
(CHEMBL266515 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)53(24-13-16-34-78)91-65(104)54(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002185
(CHEMBL438741 | Tyr-Gly-Gly-Phe-Leu-Lys(Ac)-Arg-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-55(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(26-18-36-87-76(82)83)93-67(107)54(25-14-17-35-86-48(7)101)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002178
(CHEMBL440446 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-13-15-33-87-47(7)103)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-12-14-32-78)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002186
(CHEMBL440987 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(25-14-17-35-86-48(7)101)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(27-19-37-88-77(84)85)93-67(107)55(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002182
(CHEMBL415617 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(24-13-16-34-78)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(26-18-36-86-75(83)84)91-65(104)53(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002178
(CHEMBL440446 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-13-15-33-87-47(7)103)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-12-14-32-78)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002183
(CHEMBL266515 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)53(24-13-16-34-78)91-65(104)54(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002179
(CHEMBL263597 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)=O)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-12-14-32-78)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-13-15-33-87-47(7)103)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002181
(CHEMBL266717 | Tyr-Gly-Gly-Phe-Leu-Lys-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-53(24-13-16-34-78)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(25-17-35-85-74(81)82)91-65(104)52(23-12-15-33-77)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002180
(CHEMBL263583 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys(Ac)-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)55(25-14-17-35-86-48(7)101)93-67(107)56(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards kappa opioid receptor in guinea pig cerebellar membrane using [3H]-bremazocine |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50002179
(CHEMBL263597 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)=O)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-12-14-32-78)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-13-15-33-87-47(7)103)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002180
(CHEMBL263583 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys(Ac)-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)55(25-14-17-35-86-48(7)101)93-67(107)56(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards mu-opioid receptor in rat forebrain membrane using [3H]-DAMGO |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO to opioid receptor mu of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002185
(CHEMBL438741 | Tyr-Gly-Gly-Phe-Leu-Lys(Ac)-Arg-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-55(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(26-18-36-87-76(82)83)93-67(107)54(25-14-17-35-86-48(7)101)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002178
(CHEMBL440446 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-13-15-33-87-47(7)103)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-12-14-32-78)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002180
(CHEMBL263583 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys(Ac)-Ile...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(27-19-37-88-77(84)85)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)55(25-14-17-35-86-48(7)101)93-67(107)56(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002186
(CHEMBL440987 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H129N23O15/c1-8-47(6)64(74(114)96-57(25-14-17-35-86-48(7)101)75(115)100-38-20-28-61(100)73(113)95-54(24-13-16-34-79)68(108)97-58(39-45(2)3)70(110)92-53(65(81)105)23-12-15-33-78)99-69(109)56(27-19-37-88-77(84)85)93-67(107)55(26-18-36-87-76(82)83)94-71(111)59(40-46(4)5)98-72(112)60(42-49-21-10-9-11-22-49)91-63(104)44-89-62(103)43-90-66(106)52(80)41-50-29-31-51(102)32-30-50/h9-11,21-22,29-32,45-47,52-61,64,102H,8,12-20,23-28,33-44,78-80H2,1-7H3,(H2,81,105)(H,86,101)(H,89,103)(H,90,106)(H,91,104)(H,92,110)(H,93,107)(H,94,111)(H,95,113)(H,96,114)(H,97,108)(H,98,112)(H,99,109)(H4,82,83,87)(H4,84,85,88)/t47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002183
(CHEMBL266515 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)53(24-13-16-34-78)91-65(104)54(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002182
(CHEMBL415617 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Lys...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(24-13-16-34-78)73(112)98-37-19-27-59(98)71(110)93-52(23-12-15-33-77)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(26-18-36-86-75(83)84)91-65(104)53(25-17-35-85-74(81)82)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002184
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards delta-opioid receptor in rat forebrain membrane using [3H]-DPDPE |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002179
(CHEMBL263597 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)=O)C(N)=O Show InChI InChI=1S/C77H129N25O15/c1-8-46(6)63(73(116)98-56(26-18-36-90-77(85)86)74(117)102-37-19-27-60(102)72(115)97-53(23-12-14-32-78)67(110)99-57(38-44(2)3)69(112)94-52(64(80)107)22-13-15-33-87-47(7)103)101-68(111)55(25-17-35-89-76(83)84)95-66(109)54(24-16-34-88-75(81)82)96-70(113)58(39-45(4)5)100-71(114)59(41-48-20-10-9-11-21-48)93-62(106)43-91-61(105)42-92-65(108)51(79)40-49-28-30-50(104)31-29-49/h9-11,20-21,28-31,44-46,51-60,63,104H,8,12-19,22-27,32-43,78-79H2,1-7H3,(H2,80,107)(H,87,103)(H,91,105)(H,92,108)(H,93,106)(H,94,112)(H,95,109)(H,96,113)(H,97,115)(H,98,116)(H,99,110)(H,100,114)(H,101,111)(H4,81,82,88)(H4,83,84,89)(H4,85,86,90)/t46-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50002181
(CHEMBL266717 | Tyr-Gly-Gly-Phe-Leu-Lys-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C75H127N23O14/c1-7-46(6)62(72(111)94-55(26-18-36-86-75(83)84)73(112)98-37-19-27-59(98)71(110)93-53(24-13-16-34-78)66(105)95-56(38-44(2)3)68(107)90-51(63(80)102)22-11-14-32-76)97-67(106)54(25-17-35-85-74(81)82)91-65(104)52(23-12-15-33-77)92-69(108)57(39-45(4)5)96-70(109)58(41-47-20-9-8-10-21-47)89-61(101)43-87-60(100)42-88-64(103)50(79)40-48-28-30-49(99)31-29-48/h8-10,20-21,28-31,44-46,50-59,62,99H,7,11-19,22-27,32-43,76-79H2,1-6H3,(H2,80,102)(H,87,100)(H,88,103)(H,89,101)(H,90,107)(H,91,104)(H,92,108)(H,93,110)(H,94,111)(H,95,105)(H,96,109)(H,97,106)(H4,81,82,85)(H4,83,84,86)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DPDPE to opioid receptor delta of rat fore brain membranes was determined |
J Med Chem 35: 4330-3 (1992)
BindingDB Entry DOI: 10.7270/Q2FB51W2 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50040187
(CHEMBL404976 | Tyr-Aib-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H131N25O14/c1-9-46(6)61(71(114)97-55(27-19-37-90-76(86)87)72(115)102-38-20-28-59(102)70(113)96-52(24-14-16-34-79)65(108)98-56(39-44(2)3)67(110)93-51(62(81)105)23-13-15-33-78)100-66(109)54(26-18-36-89-75(84)85)94-64(107)53(25-17-35-88-74(82)83)95-68(111)57(40-45(4)5)99-69(112)58(42-47-21-11-10-12-22-47)92-60(104)43-91-73(116)77(7,8)101-63(106)50(80)41-48-29-31-49(103)32-30-48/h10-12,21-22,29-32,44-46,50-59,61,103H,9,13-20,23-28,33-43,78-80H2,1-8H3,(H2,81,105)(H,91,116)(H,92,104)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,108)(H,99,112)(H,100,109)(H,101,106)(H4,82,83,88)(H4,84,85,89)(H4,86,87,90)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards mu-opioid receptor in rat forebrain membrane using [3H]-DAMGO |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50040188
((cis)Tyr-1-Amino-CycloHexylcarbonyl-Phe-Leu-Arg-Ar...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCC(CC1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |wU:4.4,98.101,106.109,38.38,19.19,wD:85.89,71.73,89.92,30.30,58.61,8.8,2.2,(17.35,.41,;17.35,-.83,;18.68,-1.6,;19.75,-.98,;18.68,-3.14,;17.34,-3.9,;16.01,-3.13,;16.01,-1.9,;14.67,-3.89,;14.66,-5.43,;13.33,-6.2,;13.32,-7.74,;11.98,-8.5,;11.97,-10.04,;10.9,-10.66,;13.03,-10.66,;13.34,-3.12,;12,-3.88,;12,-5.12,;10.67,-3.11,;10.67,-1.57,;9.34,-.8,;9.34,.74,;8.01,1.52,;8.01,3.06,;6.95,3.68,;9.08,3.67,;9.33,-3.88,;8,-3.1,;8,-1.87,;6.66,-3.87,;6.66,-5.41,;5.32,-6.17,;4.25,-5.55,;5.31,-7.4,;5.33,-3.09,;4,-3.86,;3.99,-5.09,;2.66,-3.08,;2.67,-1.54,;4,-.77,;4,.77,;5.34,1.54,;6.67,.76,;6.66,-.78,;5.33,-1.54,;1.33,-3.85,;-.01,-3.07,;-0,-1.84,;-1.34,-3.84,;-2.68,-3.07,;-4.01,-3.83,;-4.01,-5.37,;-2.68,-6.15,;-1.35,-5.38,;-5.35,-6.14,;-5.35,-7.69,;-4.28,-8.3,;-6.68,-8.46,;-7.75,-7.84,;-6.68,-10,;-8.01,-10.77,;-8.02,-12.31,;-9.35,-13.08,;-10.69,-12.3,;-11.75,-12.92,;-10.68,-10.76,;-9.35,-10,;20.01,-3.91,;20.01,-5.15,;21.35,-3.15,;22.68,-3.92,;22.67,-5.46,;21.33,-6.22,;21.32,-7.77,;19.99,-8.53,;19.98,-10.07,;18.91,-10.68,;21.04,-10.69,;24.02,-3.16,;24.02,-1.92,;25.35,-3.93,;25.48,-5.45,;26.99,-5.78,;27.76,-4.45,;26.74,-3.3,;27.05,-1.8,;28.22,-1.41,;25.9,-.77,;26.22,.74,;27.68,1.22,;28.83,.19,;30.3,.67,;31.44,-.36,;32.61,.03,;25.07,1.77,;23.9,1.38,;25.38,3.28,;24.23,4.3,;22.77,3.82,;22.46,2.31,;21.29,1.92,;23.38,1.49,;24.55,5.8,;25.71,6.19,;23.4,6.83,;23.71,8.34,;22.56,9.37,;22.87,10.88,;21.73,11.91,;22.04,13.41,;21.12,14.23,;25.17,8.83,;26.09,8.01,;25.42,10.04,)| Show InChI InChI=1S/C78H132N24O13/c1-7-47(6)63(74(114)97-58(25-17-39-91-78(87)88)75(115)102-40-18-26-62(102)73(113)96-55(22-12-14-36-80)68(108)99-59(41-45(2)3)70(110)93-54(64(82)104)21-11-13-35-79)101-69(109)57(24-16-38-90-77(85)86)94-67(107)56(23-15-37-89-76(83)84)95-71(111)60(42-46(4)5)100-72(112)61(44-48-19-9-8-10-20-48)98-65(105)50-29-31-51(32-30-50)92-66(106)53(81)43-49-27-33-52(103)34-28-49/h8-10,19-20,27-28,33-34,45-47,50-51,53-63,103H,7,11-18,21-26,29-32,35-44,79-81H2,1-6H3,(H2,82,104)(H,92,106)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,105)(H,99,108)(H,100,112)(H,101,109)(H4,83,84,89)(H4,85,86,90)(H4,87,88,91)/t47-,50?,51?,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards kappa opioid receptor in guinea pig cerebellar membrane using [3H]-bremazocine |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50040188
((cis)Tyr-1-Amino-CycloHexylcarbonyl-Phe-Leu-Arg-Ar...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCC(CC1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |wU:4.4,98.101,106.109,38.38,19.19,wD:85.89,71.73,89.92,30.30,58.61,8.8,2.2,(17.35,.41,;17.35,-.83,;18.68,-1.6,;19.75,-.98,;18.68,-3.14,;17.34,-3.9,;16.01,-3.13,;16.01,-1.9,;14.67,-3.89,;14.66,-5.43,;13.33,-6.2,;13.32,-7.74,;11.98,-8.5,;11.97,-10.04,;10.9,-10.66,;13.03,-10.66,;13.34,-3.12,;12,-3.88,;12,-5.12,;10.67,-3.11,;10.67,-1.57,;9.34,-.8,;9.34,.74,;8.01,1.52,;8.01,3.06,;6.95,3.68,;9.08,3.67,;9.33,-3.88,;8,-3.1,;8,-1.87,;6.66,-3.87,;6.66,-5.41,;5.32,-6.17,;4.25,-5.55,;5.31,-7.4,;5.33,-3.09,;4,-3.86,;3.99,-5.09,;2.66,-3.08,;2.67,-1.54,;4,-.77,;4,.77,;5.34,1.54,;6.67,.76,;6.66,-.78,;5.33,-1.54,;1.33,-3.85,;-.01,-3.07,;-0,-1.84,;-1.34,-3.84,;-2.68,-3.07,;-4.01,-3.83,;-4.01,-5.37,;-2.68,-6.15,;-1.35,-5.38,;-5.35,-6.14,;-5.35,-7.69,;-4.28,-8.3,;-6.68,-8.46,;-7.75,-7.84,;-6.68,-10,;-8.01,-10.77,;-8.02,-12.31,;-9.35,-13.08,;-10.69,-12.3,;-11.75,-12.92,;-10.68,-10.76,;-9.35,-10,;20.01,-3.91,;20.01,-5.15,;21.35,-3.15,;22.68,-3.92,;22.67,-5.46,;21.33,-6.22,;21.32,-7.77,;19.99,-8.53,;19.98,-10.07,;18.91,-10.68,;21.04,-10.69,;24.02,-3.16,;24.02,-1.92,;25.35,-3.93,;25.48,-5.45,;26.99,-5.78,;27.76,-4.45,;26.74,-3.3,;27.05,-1.8,;28.22,-1.41,;25.9,-.77,;26.22,.74,;27.68,1.22,;28.83,.19,;30.3,.67,;31.44,-.36,;32.61,.03,;25.07,1.77,;23.9,1.38,;25.38,3.28,;24.23,4.3,;22.77,3.82,;22.46,2.31,;21.29,1.92,;23.38,1.49,;24.55,5.8,;25.71,6.19,;23.4,6.83,;23.71,8.34,;22.56,9.37,;22.87,10.88,;21.73,11.91,;22.04,13.41,;21.12,14.23,;25.17,8.83,;26.09,8.01,;25.42,10.04,)| Show InChI InChI=1S/C78H132N24O13/c1-7-47(6)63(74(114)97-58(25-17-39-91-78(87)88)75(115)102-40-18-26-62(102)73(113)96-55(22-12-14-36-80)68(108)99-59(41-45(2)3)70(110)93-54(64(82)104)21-11-13-35-79)101-69(109)57(24-16-38-90-77(85)86)94-67(107)56(23-15-37-89-76(83)84)95-71(111)60(42-46(4)5)100-72(112)61(44-48-19-9-8-10-20-48)98-65(105)50-29-31-51(32-30-50)92-66(106)53(81)43-49-27-33-52(103)34-28-49/h8-10,19-20,27-28,33-34,45-47,50-51,53-63,103H,7,11-18,21-26,29-32,35-44,79-81H2,1-6H3,(H2,82,104)(H,92,106)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,105)(H,99,108)(H,100,112)(H,101,109)(H4,83,84,89)(H4,85,86,90)(H4,87,88,91)/t47-,50?,51?,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards kappa opioid receptor in guinea pig cerebellar membrane using [3H]-bremazocine |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50040187
(CHEMBL404976 | Tyr-Aib-Gly-Phe-Leu-Arg-Arg-Ile-Arg...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C77H131N25O14/c1-9-46(6)61(71(114)97-55(27-19-37-90-76(86)87)72(115)102-38-20-28-59(102)70(113)96-52(24-14-16-34-79)65(108)98-56(39-44(2)3)67(110)93-51(62(81)105)23-13-15-33-78)100-66(109)54(26-18-36-89-75(84)85)94-64(107)53(25-17-35-88-74(82)83)95-68(111)57(40-45(4)5)99-69(112)58(42-47-21-11-10-12-22-47)92-60(104)43-91-73(116)77(7,8)101-63(106)50(80)41-48-29-31-49(103)32-30-48/h10-12,21-22,29-32,44-46,50-59,61,103H,9,13-20,23-28,33-43,78-80H2,1-8H3,(H2,81,105)(H,91,116)(H,92,104)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,108)(H,99,112)(H,100,109)(H,101,106)(H4,82,83,88)(H4,84,85,89)(H4,86,87,90)/t46-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards kappa opioid receptor in guinea pig cerebellar membrane using [3H]-bremazocine |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50040188
((cis)Tyr-1-Amino-CycloHexylcarbonyl-Phe-Leu-Arg-Ar...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCC(CC1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |wU:4.4,98.101,106.109,38.38,19.19,wD:85.89,71.73,89.92,30.30,58.61,8.8,2.2,(17.35,.41,;17.35,-.83,;18.68,-1.6,;19.75,-.98,;18.68,-3.14,;17.34,-3.9,;16.01,-3.13,;16.01,-1.9,;14.67,-3.89,;14.66,-5.43,;13.33,-6.2,;13.32,-7.74,;11.98,-8.5,;11.97,-10.04,;10.9,-10.66,;13.03,-10.66,;13.34,-3.12,;12,-3.88,;12,-5.12,;10.67,-3.11,;10.67,-1.57,;9.34,-.8,;9.34,.74,;8.01,1.52,;8.01,3.06,;6.95,3.68,;9.08,3.67,;9.33,-3.88,;8,-3.1,;8,-1.87,;6.66,-3.87,;6.66,-5.41,;5.32,-6.17,;4.25,-5.55,;5.31,-7.4,;5.33,-3.09,;4,-3.86,;3.99,-5.09,;2.66,-3.08,;2.67,-1.54,;4,-.77,;4,.77,;5.34,1.54,;6.67,.76,;6.66,-.78,;5.33,-1.54,;1.33,-3.85,;-.01,-3.07,;-0,-1.84,;-1.34,-3.84,;-2.68,-3.07,;-4.01,-3.83,;-4.01,-5.37,;-2.68,-6.15,;-1.35,-5.38,;-5.35,-6.14,;-5.35,-7.69,;-4.28,-8.3,;-6.68,-8.46,;-7.75,-7.84,;-6.68,-10,;-8.01,-10.77,;-8.02,-12.31,;-9.35,-13.08,;-10.69,-12.3,;-11.75,-12.92,;-10.68,-10.76,;-9.35,-10,;20.01,-3.91,;20.01,-5.15,;21.35,-3.15,;22.68,-3.92,;22.67,-5.46,;21.33,-6.22,;21.32,-7.77,;19.99,-8.53,;19.98,-10.07,;18.91,-10.68,;21.04,-10.69,;24.02,-3.16,;24.02,-1.92,;25.35,-3.93,;25.48,-5.45,;26.99,-5.78,;27.76,-4.45,;26.74,-3.3,;27.05,-1.8,;28.22,-1.41,;25.9,-.77,;26.22,.74,;27.68,1.22,;28.83,.19,;30.3,.67,;31.44,-.36,;32.61,.03,;25.07,1.77,;23.9,1.38,;25.38,3.28,;24.23,4.3,;22.77,3.82,;22.46,2.31,;21.29,1.92,;23.38,1.49,;24.55,5.8,;25.71,6.19,;23.4,6.83,;23.71,8.34,;22.56,9.37,;22.87,10.88,;21.73,11.91,;22.04,13.41,;21.12,14.23,;25.17,8.83,;26.09,8.01,;25.42,10.04,)| Show InChI InChI=1S/C78H132N24O13/c1-7-47(6)63(74(114)97-58(25-17-39-91-78(87)88)75(115)102-40-18-26-62(102)73(113)96-55(22-12-14-36-80)68(108)99-59(41-45(2)3)70(110)93-54(64(82)104)21-11-13-35-79)101-69(109)57(24-16-38-90-77(85)86)94-67(107)56(23-15-37-89-76(83)84)95-71(111)60(42-46(4)5)100-72(112)61(44-48-19-9-8-10-20-48)98-65(105)50-29-31-51(32-30-50)92-66(106)53(81)43-49-27-33-52(103)34-28-49/h8-10,19-20,27-28,33-34,45-47,50-51,53-63,103H,7,11-18,21-26,29-32,35-44,79-81H2,1-6H3,(H2,82,104)(H,92,106)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,105)(H,99,108)(H,100,112)(H,101,109)(H4,83,84,89)(H4,85,86,90)(H4,87,88,91)/t47-,50?,51?,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 117 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards delta-opioid receptor in rat forebrain membrane using [3H]-DPDPE |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50040188
((cis)Tyr-1-Amino-CycloHexylcarbonyl-Phe-Leu-Arg-Ar...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCC(CC1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |wU:4.4,98.101,106.109,38.38,19.19,wD:85.89,71.73,89.92,30.30,58.61,8.8,2.2,(17.35,.41,;17.35,-.83,;18.68,-1.6,;19.75,-.98,;18.68,-3.14,;17.34,-3.9,;16.01,-3.13,;16.01,-1.9,;14.67,-3.89,;14.66,-5.43,;13.33,-6.2,;13.32,-7.74,;11.98,-8.5,;11.97,-10.04,;10.9,-10.66,;13.03,-10.66,;13.34,-3.12,;12,-3.88,;12,-5.12,;10.67,-3.11,;10.67,-1.57,;9.34,-.8,;9.34,.74,;8.01,1.52,;8.01,3.06,;6.95,3.68,;9.08,3.67,;9.33,-3.88,;8,-3.1,;8,-1.87,;6.66,-3.87,;6.66,-5.41,;5.32,-6.17,;4.25,-5.55,;5.31,-7.4,;5.33,-3.09,;4,-3.86,;3.99,-5.09,;2.66,-3.08,;2.67,-1.54,;4,-.77,;4,.77,;5.34,1.54,;6.67,.76,;6.66,-.78,;5.33,-1.54,;1.33,-3.85,;-.01,-3.07,;-0,-1.84,;-1.34,-3.84,;-2.68,-3.07,;-4.01,-3.83,;-4.01,-5.37,;-2.68,-6.15,;-1.35,-5.38,;-5.35,-6.14,;-5.35,-7.69,;-4.28,-8.3,;-6.68,-8.46,;-7.75,-7.84,;-6.68,-10,;-8.01,-10.77,;-8.02,-12.31,;-9.35,-13.08,;-10.69,-12.3,;-11.75,-12.92,;-10.68,-10.76,;-9.35,-10,;20.01,-3.91,;20.01,-5.15,;21.35,-3.15,;22.68,-3.92,;22.67,-5.46,;21.33,-6.22,;21.32,-7.77,;19.99,-8.53,;19.98,-10.07,;18.91,-10.68,;21.04,-10.69,;24.02,-3.16,;24.02,-1.92,;25.35,-3.93,;25.48,-5.45,;26.99,-5.78,;27.76,-4.45,;26.74,-3.3,;27.05,-1.8,;28.22,-1.41,;25.9,-.77,;26.22,.74,;27.68,1.22,;28.83,.19,;30.3,.67,;31.44,-.36,;32.61,.03,;25.07,1.77,;23.9,1.38,;25.38,3.28,;24.23,4.3,;22.77,3.82,;22.46,2.31,;21.29,1.92,;23.38,1.49,;24.55,5.8,;25.71,6.19,;23.4,6.83,;23.71,8.34,;22.56,9.37,;22.87,10.88,;21.73,11.91,;22.04,13.41,;21.12,14.23,;25.17,8.83,;26.09,8.01,;25.42,10.04,)| Show InChI InChI=1S/C78H132N24O13/c1-7-47(6)63(74(114)97-58(25-17-39-91-78(87)88)75(115)102-40-18-26-62(102)73(113)96-55(22-12-14-36-80)68(108)99-59(41-45(2)3)70(110)93-54(64(82)104)21-11-13-35-79)101-69(109)57(24-16-38-90-77(85)86)94-67(107)56(23-15-37-89-76(83)84)95-71(111)60(42-46(4)5)100-72(112)61(44-48-19-9-8-10-20-48)98-65(105)50-29-31-51(32-30-50)92-66(106)53(81)43-49-27-33-52(103)34-28-49/h8-10,19-20,27-28,33-34,45-47,50-51,53-63,103H,7,11-18,21-26,29-32,35-44,79-81H2,1-6H3,(H2,82,104)(H,92,106)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,105)(H,99,108)(H,100,112)(H,101,109)(H4,83,84,89)(H4,85,86,90)(H4,87,88,91)/t47-,50?,51?,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards mu-opioid receptor in rat forebrain membrane using [3H]-DAMGO |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50040188
((cis)Tyr-1-Amino-CycloHexylcarbonyl-Phe-Leu-Arg-Ar...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCC(CC1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |wU:4.4,98.101,106.109,38.38,19.19,wD:85.89,71.73,89.92,30.30,58.61,8.8,2.2,(17.35,.41,;17.35,-.83,;18.68,-1.6,;19.75,-.98,;18.68,-3.14,;17.34,-3.9,;16.01,-3.13,;16.01,-1.9,;14.67,-3.89,;14.66,-5.43,;13.33,-6.2,;13.32,-7.74,;11.98,-8.5,;11.97,-10.04,;10.9,-10.66,;13.03,-10.66,;13.34,-3.12,;12,-3.88,;12,-5.12,;10.67,-3.11,;10.67,-1.57,;9.34,-.8,;9.34,.74,;8.01,1.52,;8.01,3.06,;6.95,3.68,;9.08,3.67,;9.33,-3.88,;8,-3.1,;8,-1.87,;6.66,-3.87,;6.66,-5.41,;5.32,-6.17,;4.25,-5.55,;5.31,-7.4,;5.33,-3.09,;4,-3.86,;3.99,-5.09,;2.66,-3.08,;2.67,-1.54,;4,-.77,;4,.77,;5.34,1.54,;6.67,.76,;6.66,-.78,;5.33,-1.54,;1.33,-3.85,;-.01,-3.07,;-0,-1.84,;-1.34,-3.84,;-2.68,-3.07,;-4.01,-3.83,;-4.01,-5.37,;-2.68,-6.15,;-1.35,-5.38,;-5.35,-6.14,;-5.35,-7.69,;-4.28,-8.3,;-6.68,-8.46,;-7.75,-7.84,;-6.68,-10,;-8.01,-10.77,;-8.02,-12.31,;-9.35,-13.08,;-10.69,-12.3,;-11.75,-12.92,;-10.68,-10.76,;-9.35,-10,;20.01,-3.91,;20.01,-5.15,;21.35,-3.15,;22.68,-3.92,;22.67,-5.46,;21.33,-6.22,;21.32,-7.77,;19.99,-8.53,;19.98,-10.07,;18.91,-10.68,;21.04,-10.69,;24.02,-3.16,;24.02,-1.92,;25.35,-3.93,;25.48,-5.45,;26.99,-5.78,;27.76,-4.45,;26.74,-3.3,;27.05,-1.8,;28.22,-1.41,;25.9,-.77,;26.22,.74,;27.68,1.22,;28.83,.19,;30.3,.67,;31.44,-.36,;32.61,.03,;25.07,1.77,;23.9,1.38,;25.38,3.28,;24.23,4.3,;22.77,3.82,;22.46,2.31,;21.29,1.92,;23.38,1.49,;24.55,5.8,;25.71,6.19,;23.4,6.83,;23.71,8.34,;22.56,9.37,;22.87,10.88,;21.73,11.91,;22.04,13.41,;21.12,14.23,;25.17,8.83,;26.09,8.01,;25.42,10.04,)| Show InChI InChI=1S/C78H132N24O13/c1-7-47(6)63(74(114)97-58(25-17-39-91-78(87)88)75(115)102-40-18-26-62(102)73(113)96-55(22-12-14-36-80)68(108)99-59(41-45(2)3)70(110)93-54(64(82)104)21-11-13-35-79)101-69(109)57(24-16-38-90-77(85)86)94-67(107)56(23-15-37-89-76(83)84)95-71(111)60(42-46(4)5)100-72(112)61(44-48-19-9-8-10-20-48)98-65(105)50-29-31-51(32-30-50)92-66(106)53(81)43-49-27-33-52(103)34-28-49/h8-10,19-20,27-28,33-34,45-47,50-51,53-63,103H,7,11-18,21-26,29-32,35-44,79-81H2,1-6H3,(H2,82,104)(H,92,106)(H,93,110)(H,94,107)(H,95,111)(H,96,113)(H,97,114)(H,98,105)(H,99,108)(H,100,112)(H,101,109)(H4,83,84,89)(H4,85,86,90)(H4,87,88,91)/t47-,50?,51?,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity towards delta-opioid receptor in rat forebrain membrane using [3H]-DPDPE |
J Med Chem 36: 1100-3 (1993)
BindingDB Entry DOI: 10.7270/Q2639NS3 |
More data for this
Ligand-Target Pair | |
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