Compile Data Set for Download or QSAR

Found 20 hits with Last Name = 'sola' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC6				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214702 (US9296728, 25) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H19NO4/c26-23(27)21-13-19-11-12-20(14-22(19)29-24(21)28)25(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 3282-3286 (2016) Article DOI: 10.1016/j.bmcl.2016.05.054 BindingDB Entry DOI: 10.7270/Q2BP04QP
					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214700 (US9296728, 23) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC=C)CC=C Show InChI InChI=1S/C16H15NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h3-6,9-10H,1-2,7-8H2,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 3282-3286 (2016) Article DOI: 10.1016/j.bmcl.2016.05.054 BindingDB Entry DOI: 10.7270/Q2BP04QP
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC1				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC3				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC10				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214701 (US9296728, 24) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC#C)CC#C Show InChI InChI=1S/C16H11NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h1-2,5-6,9-10H,7-8H2,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 3282-3286 (2016) Article DOI: 10.1016/j.bmcl.2016.05.054 BindingDB Entry DOI: 10.7270/Q2BP04QP
					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50442702 (CHEMBL2442511 | US9296728, 26) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1 Show InChI InChI=1S/C14H13NO4/c16-13(17)11-7-9-3-4-10(15-5-1-2-6-15)8-12(9)19-14(11)18/h3-4,7-8H,1-2,5-6H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 3282-3286 (2016) Article DOI: 10.1016/j.bmcl.2016.05.054 BindingDB Entry DOI: 10.7270/Q2BP04QP
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC2				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50326167 (CHEMBL1243261 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)c1cc(CCCCC(=O)Nc2ccccc2)on1 Show InChI InChI=1S/C15H17N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,10,21H,4-5,8-9H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC6				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214699 (US9296728, 22) Show SMILES CCCN(CCC)c1ccc2cc(C(O)=O)c(=O)oc2c1 Show InChI InChI=1S/C16H19NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h5-6,9-10H,3-4,7-8H2,1-2H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 3282-3286 (2016) Article DOI: 10.1016/j.bmcl.2016.05.054 BindingDB Entry DOI: 10.7270/Q2BP04QP
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50326168 (CHEMBL1243289 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)C1=NOC(CCCCC(=O)Nc2ccccc2)C1 |t:4| Show InChI InChI=1S/C15H19N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,12,21H,4-5,8-10H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC6				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50326167 (CHEMBL1243261 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)c1cc(CCCCC(=O)Nc2ccccc2)on1 Show InChI InChI=1S/C15H17N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,10,21H,4-5,8-9H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC1				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50326167 (CHEMBL1243261 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)c1cc(CCCCC(=O)Nc2ccccc2)on1 Show InChI InChI=1S/C15H17N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,10,21H,4-5,8-9H2,(H,16,19)(H,17,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC10				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50326168 (CHEMBL1243289 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)C1=NOC(CCCCC(=O)Nc2ccccc2)C1 |t:4| Show InChI InChI=1S/C15H19N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,12,21H,4-5,8-10H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC1				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50326167 (CHEMBL1243261 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)c1cc(CCCCC(=O)Nc2ccccc2)on1 Show InChI InChI=1S/C15H17N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,10,21H,4-5,8-9H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC2				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50326168 (CHEMBL1243289 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)C1=NOC(CCCCC(=O)Nc2ccccc2)C1 |t:4| Show InChI InChI=1S/C15H19N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,12,21H,4-5,8-10H2,(H,16,19)(H,17,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC10				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50326167 (CHEMBL1243261 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)c1cc(CCCCC(=O)Nc2ccccc2)on1 Show InChI InChI=1S/C15H17N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,10,21H,4-5,8-9H2,(H,16,19)(H,17,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC3				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50326168 (CHEMBL1243289 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)C1=NOC(CCCCC(=O)Nc2ccccc2)C1 |t:4| Show InChI InChI=1S/C15H19N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,12,21H,4-5,8-10H2,(H,16,19)(H,17,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC3				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50326168 (CHEMBL1243289 | N-Hydroxy-5-[5-oxo-5-(phenylamino)...) Show SMILES ONC(=O)C1=NOC(CCCCC(=O)Nc2ccccc2)C1 |t:4| Show InChI InChI=1S/C15H19N3O4/c19-14(16-11-6-2-1-3-7-11)9-5-4-8-12-10-13(18-22-12)15(20)17-21/h1-3,6-7,12,21H,4-5,8-10H2,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC2				Eur J Med Chem 45: 4331-8 (2010) Article DOI: 10.1016/j.ejmech.2010.06.035 BindingDB Entry DOI: 10.7270/Q20Z73GF
					More data for this Ligand-Target Pair