Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'temelkoff' and Initial = 'dp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50170870 (CHEMBL3805182) Show SMILES [H][C@@]12CCCCN1C(=O)c1c2c(C(N)=O)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-14-5-3-4-12(19(14)25)8-11-9-13-16(22(26)30)17-15-6-1-2-7-28(15)23(31)18(17)21(29)20(13)27-10-11/h3-5,9-10,15,29H,1-2,6-8H2,(H2,26,30)/t15-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170867 (CHEMBL3806067) Show SMILES [H][C@]12CCCCN1C(=O)c1c2c(C(N)=O)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-14-5-3-4-12(19(14)25)8-11-9-13-16(22(26)30)17-15-6-1-2-7-28(15)23(31)18(17)21(29)20(13)27-10-11/h3-5,9-10,15,29H,1-2,6-8H2,(H2,26,30)/t15-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170867 (CHEMBL3806067) Show SMILES [H][C@]12CCCCN1C(=O)c1c2c(C(N)=O)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-14-5-3-4-12(19(14)25)8-11-9-13-16(22(26)30)17-15-6-1-2-7-28(15)23(31)18(17)21(29)20(13)27-10-11/h3-5,9-10,15,29H,1-2,6-8H2,(H2,26,30)/t15-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170591 (CHEMBL2403116) Show SMILES [H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4)c(=O)c(O)c3C(=O)N1CCCO2 |r| Show InChI InChI=1S/C19H18FN3O5/c20-12-4-2-11(3-5-12)8-21-18(26)13-9-22-10-14-23(6-1-7-28-14)19(27)15(22)17(25)16(13)24/h2-5,9,14,25H,1,6-8,10H2,(H,21,26)/t14-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170870 (CHEMBL3805182) Show SMILES [H][C@@]12CCCCN1C(=O)c1c2c(C(N)=O)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-14-5-3-4-12(19(14)25)8-11-9-13-16(22(26)30)17-15-6-1-2-7-28(15)23(31)18(17)21(29)20(13)27-10-11/h3-5,9-10,15,29H,1-2,6-8H2,(H2,26,30)/t15-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170604 (CHEMBL3805585) Show SMILES Oc1c2C(=O)N3CCCN3Cc2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc12 Show InChI InChI=1S/C22H16ClFN4O2/c23-17-4-1-3-13(19(17)24)7-12-8-14-15(9-25)16-11-27-5-2-6-28(27)22(30)18(16)21(29)20(14)26-10-12/h1,3-4,8,10,29H,2,5-7,11H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50062551 (CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572) Show SMILES [H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N1[C@H](C)CCO2 |r| Show InChI InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...				J Med Chem 56: 5901-16 (2013) Article DOI: 10.1021/jm400645w BindingDB Entry DOI: 10.7270/Q21G0Q64
					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrase (Human immunodeficiency virus 1)	BDBM50045107 (CHEMBL1256978 | GSK364735) Show SMILES Cn1c2cc(Cc3ccc(F)cc3)cnc2c(O)c(C(=O)NCCO)c1=O Show InChI InChI=1S/C19H18FN3O4/c1-23-14-9-12(8-11-2-4-13(20)5-3-11)10-22-16(14)17(25)15(19(23)27)18(26)21-6-7-24/h2-5,9-10,24-25H,6-8H2,1H3,(H,21,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170865 (CHEMBL3805145) Show SMILES [H][C@@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C(N)=O)c1C2 |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-16-5-1-3-12(19(16)25)7-11-8-15-17(22(26)30)14-9-13-4-2-6-28(13)23(31)18(14)21(29)20(15)27-10-11/h1,3,5,8,10,13,29H,2,4,6-7,9H2,(H2,26,30)/t13-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50492496 (Cabotegravir | GSK-1265744A | GSK1265744 | GSK1265...) Show SMILES [H][C@@]12Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N1[C@@H](C)CO2 |r| Show InChI InChI=1S/C19H17F2N3O5/c1-9-8-29-14-7-23-6-12(16(25)17(26)15(23)19(28)24(9)14)18(27)22-5-10-2-3-11(20)4-13(10)21/h2-4,6,9,14,26H,5,7-8H2,1H3,(H,22,27)/t9-,14+/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...				J Med Chem 56: 5901-16 (2013) Article DOI: 10.1021/jm400645w BindingDB Entry DOI: 10.7270/Q21G0Q64
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170819 (CHEMBL3805531) Show SMILES [H][C@]12CCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C22H15ClFN3O2/c23-15-4-1-3-12(19(15)24)7-11-8-13-14(9-25)17-16-5-2-6-27(16)22(29)18(17)21(28)20(13)26-10-11/h1,3-4,8,10,16,28H,2,5-7H2/t16-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50492497 (CHEMBL2403118) Show SMILES [H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4)c(=O)c(O)c3C(=O)N1CC[C@@H](C)O2 |r| Show InChI InChI=1S/C20H20FN3O5/c1-11-6-7-24-15(29-11)10-23-9-14(17(25)18(26)16(23)20(24)28)19(27)22-8-12-2-4-13(21)5-3-12/h2-5,9,11,15,26H,6-8,10H2,1H3,(H,22,27)/t11-,15+/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...				J Med Chem 56: 5901-16 (2013) Article DOI: 10.1021/jm400645w BindingDB Entry DOI: 10.7270/Q21G0Q64
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170607 (CHEMBL3805498) Show SMILES [H][C@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C#N)c1C2 |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-18-5-1-3-13(20(18)25)7-12-8-16-17(10-26)15-9-14-4-2-6-28(14)23(30)19(15)22(29)21(16)27-11-12/h1,3,5,8,11,14,29H,2,4,6-7,9H2/t14-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170864 (CHEMBL3805726) Show SMILES [H][C@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C(N)=O)c1C2 |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-16-5-1-3-12(19(16)25)7-11-8-15-17(22(26)30)14-9-13-4-2-6-28(13)23(31)18(14)21(29)20(15)27-10-11/h1,3,5,8,10,13,29H,2,4,6-7,9H2,(H2,26,30)/t13-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170835 (CHEMBL3804966) Show SMILES [H][C@@]12CCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C22H15ClFN3O2/c23-15-4-1-3-12(19(15)24)7-11-8-13-14(9-25)17-16-5-2-6-27(16)22(29)18(17)21(28)20(13)26-10-11/h1,3-4,8,10,16,28H,2,5-7H2/t16-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170725 (CHEMBL3805132) Show SMILES [H][C@@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C#N)c1C2 |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-18-5-1-3-13(20(18)25)7-12-8-16-17(10-26)15-9-14-4-2-6-28(14)23(30)19(15)22(29)21(16)27-11-12/h1,3,5,8,11,14,29H,2,4,6-7,9H2/t14-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170772 (CHEMBL3805269) Show SMILES [H][C@]12CCCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-16-5-3-4-13(20(16)25)8-12-9-14-15(10-26)18-17-6-1-2-7-28(17)23(30)19(18)22(29)21(14)27-11-12/h3-5,9,11,17,29H,1-2,6-8H2/t17-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170865 (CHEMBL3805145) Show SMILES [H][C@@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C(N)=O)c1C2 |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-16-5-1-3-12(19(16)25)7-11-8-15-17(22(26)30)14-9-13-4-2-6-28(13)23(31)18(14)21(29)20(15)27-10-11/h1,3,5,8,10,13,29H,2,4,6-7,9H2,(H2,26,30)/t13-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170596 (CHEMBL3805532) Show SMILES Oc1c2C(=O)N3CCCN3Cc2cc2cc(Cc3cccc(Cl)c3F)cnc12 Show InChI InChI=1S/C21H17ClFN3O2/c22-16-4-1-3-13(18(16)23)7-12-8-14-9-15-11-25-5-2-6-26(25)21(28)17(15)20(27)19(14)24-10-12/h1,3-4,8-10,27H,2,5-7,11H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170778 (CHEMBL3806308) Show SMILES [H][C@@]12CCCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-16-5-3-4-13(20(16)25)8-12-9-14-15(10-26)18-17-6-1-2-7-28(17)23(30)19(18)22(29)21(14)27-11-12/h3-5,9,11,17,29H,1-2,6-8H2/t17-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170864 (CHEMBL3805726) Show SMILES [H][C@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C(N)=O)c1C2 |r| Show InChI InChI=1S/C23H19ClFN3O3/c24-16-5-1-3-12(19(16)25)7-11-8-15-17(22(26)30)14-9-13-4-2-6-28(13)23(31)18(14)21(29)20(15)27-10-11/h1,3,5,8,10,13,29H,2,4,6-7,9H2,(H2,26,30)/t13-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170725 (CHEMBL3805132) Show SMILES [H][C@@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C#N)c1C2 |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-18-5-1-3-13(20(18)25)7-12-8-16-17(10-26)15-9-14-4-2-6-28(14)23(30)19(15)22(29)21(16)27-11-12/h1,3,5,8,11,14,29H,2,4,6-7,9H2/t14-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170596 (CHEMBL3805532) Show SMILES Oc1c2C(=O)N3CCCN3Cc2cc2cc(Cc3cccc(Cl)c3F)cnc12 Show InChI InChI=1S/C21H17ClFN3O2/c22-16-4-1-3-13(18(16)23)7-12-8-14-9-15-11-25-5-2-6-26(25)21(28)17(15)20(27)19(14)24-10-12/h1,3-4,8-10,27H,2,5-7,11H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170819 (CHEMBL3805531) Show SMILES [H][C@]12CCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C22H15ClFN3O2/c23-15-4-1-3-12(19(15)24)7-11-8-13-14(9-25)17-16-5-2-6-27(16)22(29)18(17)21(28)20(13)26-10-11/h1,3-4,8,10,16,28H,2,5-7H2/t16-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170604 (CHEMBL3805585) Show SMILES Oc1c2C(=O)N3CCCN3Cc2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc12 Show InChI InChI=1S/C22H16ClFN4O2/c23-17-4-1-3-13(19(17)24)7-12-8-14-15(9-25)16-11-27-5-2-6-28(27)22(30)18(16)21(29)20(14)26-10-12/h1,3-4,8,10,29H,2,5-7,11H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	415	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170772 (CHEMBL3805269) Show SMILES [H][C@]12CCCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-16-5-3-4-13(20(16)25)8-12-9-14-15(10-26)18-17-6-1-2-7-28(17)23(30)19(18)22(29)21(14)27-11-12/h3-5,9,11,17,29H,1-2,6-8H2/t17-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170778 (CHEMBL3806308) Show SMILES [H][C@@]12CCCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-16-5-3-4-13(20(16)25)8-12-9-14-15(10-26)18-17-6-1-2-7-28(17)23(30)19(18)22(29)21(14)27-11-12/h3-5,9,11,17,29H,1-2,6-8H2/t17-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170835 (CHEMBL3804966) Show SMILES [H][C@@]12CCCN1C(=O)c1c2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc2c1O |r| Show InChI InChI=1S/C22H15ClFN3O2/c23-15-4-1-3-12(19(15)24)7-11-8-13-14(9-25)17-16-5-2-6-27(16)22(29)18(17)21(28)20(13)26-10-11/h1,3-4,8,10,16,28H,2,5-7H2/t16-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50170607 (CHEMBL3805498) Show SMILES [H][C@]12CCCN1C(=O)c1c(O)c3ncc(Cc4cccc(Cl)c4F)cc3c(C#N)c1C2 |r| Show InChI InChI=1S/C23H17ClFN3O2/c24-18-5-1-3-13(20(18)25)7-12-8-16-17(10-26)15-9-14-4-2-6-28(14)23(30)19(15)22(29)21(16)27-11-12/h1,3,5,8,11,14,29H,2,4,6-7,9H2/t14-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...				Eur J Med Chem 117: 99-112 (2016) Article DOI: 10.1016/j.ejmech.2016.03.038 BindingDB Entry DOI: 10.7270/Q2G162R8
					More data for this Ligand-Target Pair