Compile Data Set for Download or QSAR

Found 53 hits with Last Name = 'tesfai' and Initial = 'z'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111316 (8-[4-(3,6-Dioxo-5-{4-[(thiophene-2-carbonyl)-amino...) Show SMILES OC(=O)CCCCCCCOc1ccc(\C=c2\[nH]c(=O)\c(=C\c3ccc(NC(=O)c4cccs4)cc3)[nH]c2=O)cc1 Show InChI InChI=1S/C31H31N3O6S/c35-28(36)8-4-2-1-3-5-17-40-24-15-11-22(12-16-24)20-26-30(38)33-25(29(37)34-26)19-21-9-13-23(14-10-21)32-31(39)27-7-6-18-41-27/h6-7,9-16,18-20H,1-5,8,17H2,(H,32,39)(H,33,38)(H,34,37)(H,35,36)/b25-19-,26-20+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111273 (6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2-dihydr...) Show SMILES Oc1c(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)c(=O)[nH]c2ccc(cc12)-c1cc2ccccc2s1 Show InChI InChI=1S/C32H30N6O4S/c39-30-25-18-22(28-19-21-8-4-5-9-27(21)43-28)10-15-26(25)35-32(41)29(30)31(40)34-23-11-13-24(14-12-23)42-17-7-3-1-2-6-16-38-20-33-36-37-38/h4-5,8-15,18-20H,1-3,6-7,16-17H2,(H,34,40)(H2,35,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111280 (1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dihydro-1H...) Show SMILES Clc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)C1=O Show InChI InChI=1S/C25H27ClN6O4/c26-18-6-10-20(11-7-18)32-16-22(33)23(25(32)35)24(34)28-19-8-12-21(13-9-19)36-15-5-3-1-2-4-14-31-17-27-29-30-31/h6-13,17,23H,1-5,14-16H2,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111298 (8-{4-[(7-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3ccc(cc3[nH]c2=O)-c2cc3ccccc3s2)cc1 Show InChI InChI=1S/C32H30N2O6S/c35-28(36)10-4-2-1-3-7-17-40-23-14-12-22(13-15-23)33-31(38)29-30(37)24-16-11-21(18-25(24)34-32(29)39)27-19-20-8-5-6-9-26(20)41-27/h5-6,8-9,11-16,18-19H,1-4,7,10,17H2,(H,33,38)(H,35,36)(H2,34,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111292 (8-{4-[(6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)-c2cc3ccccc3s2)cc1 Show InChI InChI=1S/C32H30N2O6S/c35-28(36)10-4-2-1-3-7-17-40-23-14-12-22(13-15-23)33-31(38)29-30(37)24-18-21(11-16-25(24)34-32(29)39)27-19-20-8-5-6-9-26(20)41-27/h5-6,8-9,11-16,18-19H,1-4,7,10,17H2,(H,33,38)(H,35,36)(H2,34,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111309 (8-{4-[(6-Benzo[b]thiophen-3-yl-4-hydroxy-2-oxo-1,2...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)-c2csc3ccccc23)cc1 Show InChI InChI=1S/C32H30N2O6S/c35-28(36)10-4-2-1-3-7-17-40-22-14-12-21(13-15-22)33-31(38)29-30(37)24-18-20(11-16-26(24)34-32(29)39)25-19-41-27-9-6-5-8-23(25)27/h5-6,8-9,11-16,18-19H,1-4,7,10,17H2,(H,33,38)(H,35,36)(H2,34,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111316 (8-[4-(3,6-Dioxo-5-{4-[(thiophene-2-carbonyl)-amino...) Show SMILES OC(=O)CCCCCCCOc1ccc(\C=c2\[nH]c(=O)\c(=C\c3ccc(NC(=O)c4cccs4)cc3)[nH]c2=O)cc1 Show InChI InChI=1S/C31H31N3O6S/c35-28(36)8-4-2-1-3-5-17-40-24-15-11-22(12-16-24)20-26-30(38)33-25(29(37)34-26)19-21-9-13-23(14-10-21)32-31(39)27-7-6-18-41-27/h6-7,9-16,18-20H,1-5,8,17H2,(H,32,39)(H,33,38)(H,34,37)(H,35,36)/b25-19-,26-20+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111281 (8-{4-[(4-Hydroxy-7-naphthalen-2-yl-2-oxo-1,2-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3ccc(cc3[nH]c2=O)-c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C34H32N2O6/c37-30(38)10-4-2-1-3-7-19-42-27-16-14-26(15-17-27)35-33(40)31-32(39)28-18-13-25(21-29(28)36-34(31)41)24-12-11-22-8-5-6-9-23(22)20-24/h5-6,8-9,11-18,20-21H,1-4,7,10,19H2,(H,35,40)(H,37,38)(H2,36,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111282 (8-{4-[(4-Hydroxy-6-naphthalen-2-yl-2-oxo-1,2-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)-c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C34H32N2O6/c37-30(38)10-4-2-1-3-7-19-42-27-16-14-26(15-17-27)35-33(40)31-32(39)28-21-25(13-18-29(28)36-34(31)41)24-12-11-22-8-5-6-9-23(22)20-24/h5-6,8-9,11-18,20-21H,1-4,7,10,19H2,(H,35,40)(H,37,38)(H2,36,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111280 (1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dihydro-1H...) Show SMILES Clc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)C1=O Show InChI InChI=1S/C25H27ClN6O4/c26-18-6-10-20(11-7-18)32-16-22(33)23(25(32)35)24(34)28-19-8-12-21(13-9-19)36-15-5-3-1-2-4-14-31-17-27-29-30-31/h6-13,17,23H,1-5,14-16H2,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111279 (4-Hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyrrole-3...) Show SMILES Cc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)C1=O Show InChI InChI=1S/C26H30N6O4/c1-19-7-11-21(12-8-19)32-17-23(33)24(26(32)35)25(34)28-20-9-13-22(14-10-20)36-16-6-4-2-3-5-15-31-18-27-29-30-31/h7-14,18,24H,2-6,15-17H2,1H3,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111279 (4-Hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyrrole-3...) Show SMILES Cc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)C1=O Show InChI InChI=1S/C26H30N6O4/c1-19-7-11-21(12-8-19)32-17-23(33)24(26(32)35)25(34)28-20-9-13-22(14-10-20)36-16-6-4-2-3-5-15-31-18-27-29-30-31/h7-14,18,24H,2-6,15-17H2,1H3,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111286 (8-{4-[(7-Cyano-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3ccc(cc3[nH]c2=O)C#N)cc1 Show InChI InChI=1S/C25H25N3O6/c26-15-16-7-12-19-20(14-16)28-25(33)22(23(19)31)24(32)27-17-8-10-18(11-9-17)34-13-5-3-1-2-4-6-21(29)30/h7-12,14H,1-6,13H2,(H,27,32)(H,29,30)(H2,28,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111309 (8-{4-[(6-Benzo[b]thiophen-3-yl-4-hydroxy-2-oxo-1,2...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)-c2csc3ccccc23)cc1 Show InChI InChI=1S/C32H30N2O6S/c35-28(36)10-4-2-1-3-7-17-40-22-14-12-21(13-15-22)33-31(38)29-30(37)24-18-20(11-16-26(24)34-32(29)39)25-19-41-27-9-6-5-8-23(25)27/h5-6,8-9,11-16,18-19H,1-4,7,10,17H2,(H,33,38)(H,35,36)(H2,34,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111273 (6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2-dihydr...) Show SMILES Oc1c(C(=O)Nc2ccc(OCCCCCCCn3cnnn3)cc2)c(=O)[nH]c2ccc(cc12)-c1cc2ccccc2s1 Show InChI InChI=1S/C32H30N6O4S/c39-30-25-18-22(28-19-21-8-4-5-9-27(21)43-28)10-15-26(25)35-32(41)29(30)31(40)34-23-11-13-24(14-12-23)42-17-7-3-1-2-6-16-38-20-33-36-37-38/h4-5,8-15,18-20H,1-3,6-7,16-17H2,(H,34,40)(H2,35,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111284 (8-{4-[(4-Hydroxy-2-oxo-7-trifluoromethyl-1,2-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3ccc(cc3[nH]c2=O)C(F)(F)F)cc1 Show InChI InChI=1S/C25H25F3N2O6/c26-25(27,28)15-7-12-18-19(14-15)30-24(35)21(22(18)33)23(34)29-16-8-10-17(11-9-16)36-13-5-3-1-2-4-6-20(31)32/h7-12,14H,1-6,13H2,(H,29,34)(H,31,32)(H2,30,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111299 (8-{4-[(4-Hydroxy-6,7-dimethoxy-2-oxo-1,2-dihydro-q...) Show SMILES COc1cc2[nH]c(=O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(O)c2cc1OC Show InChI InChI=1S/C26H30N2O8/c1-34-20-14-18-19(15-21(20)35-2)28-26(33)23(24(18)31)25(32)27-16-9-11-17(12-10-16)36-13-7-5-3-4-6-8-22(29)30/h9-12,14-15H,3-8,13H2,1-2H3,(H,27,32)(H,29,30)(H2,28,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111319 (8-{4-[(4-Hydroxy-2-oxo-6-pentyl-1,2-dihydro-quinol...) Show SMILES CCCCCc1ccc2[nH]c(=O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(O)c2c1 Show InChI InChI=1S/C29H36N2O6/c1-2-3-7-10-20-12-17-24-23(19-20)27(34)26(29(36)31-24)28(35)30-21-13-15-22(16-14-21)37-18-9-6-4-5-8-11-25(32)33/h12-17,19H,2-11,18H2,1H3,(H,30,35)(H,32,33)(H2,31,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111306 (8-{4-[(4-Hydroxy-2-oxo-1,2-dihydro-quinoline-3-car...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3ccccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H26N2O6/c27-20(28)10-4-2-1-3-7-15-32-17-13-11-16(12-14-17)25-23(30)21-22(29)18-8-5-6-9-19(18)26-24(21)31/h5-6,8-9,11-14H,1-4,7,10,15H2,(H,25,30)(H,27,28)(H2,26,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111313 (8-{4-[(6-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinol...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(Cl)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H25ClN2O6/c25-15-7-12-19-18(14-15)22(30)21(24(32)27-19)23(31)26-16-8-10-17(11-9-16)33-13-5-3-1-2-4-6-20(28)29/h7-12,14H,1-6,13H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111285 (8-(4-(4-hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyr...) Show SMILES Cc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C26H30N2O6/c1-18-8-12-20(13-9-18)28-17-22(29)24(26(28)33)25(32)27-19-10-14-21(15-11-19)34-16-6-4-2-3-5-7-23(30)31/h8-15,24H,2-7,16-17H2,1H3,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111288 (8-(4-{[1-(4-Bromo-phenyl)-4-hydroxy-2-oxo-2,5-dihy...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C25H27BrN2O6/c26-17-7-11-19(12-8-17)28-16-21(29)23(25(28)33)24(32)27-18-9-13-20(14-10-18)34-15-5-3-1-2-4-6-22(30)31/h7-14,23H,1-6,15-16H2,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111295 (8-(4-{[6-(4-Chloro-phenyl)-4-hydroxy-2-oxo-1,2-dih...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)-c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C30H29ClN2O6/c31-21-10-7-19(8-11-21)20-9-16-25-24(18-20)28(36)27(30(38)33-25)29(37)32-22-12-14-23(15-13-22)39-17-5-3-1-2-4-6-26(34)35/h7-16,18H,1-6,17H2,(H,32,37)(H,34,35)(H2,33,36,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111308 (8-{4-[(4-Hydroxy-6-iodo-2-oxo-1,2-dihydro-quinolin...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(I)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H25IN2O6/c25-15-7-12-19-18(14-15)22(30)21(24(32)27-19)23(31)26-16-8-10-17(11-9-16)33-13-5-3-1-2-4-6-20(28)29/h7-12,14H,1-6,13H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111296 (8-(4-{[4-Hydroxy-1-(4-isopropyl-phenyl)-2-oxo-2,5-...) Show SMILES CC(C)c1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C28H34N2O6/c1-19(2)20-9-13-22(14-10-20)30-18-24(31)26(28(30)35)27(34)29-21-11-15-23(16-12-21)36-17-7-5-3-4-6-8-25(32)33/h9-16,19,26H,3-8,17-18H2,1-2H3,(H,29,34)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111314 (8-{4-[(6,7-Difluoro-4-hydroxy-2-oxo-1,2-dihydro-qu...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(F)c(F)cc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H24F2N2O6/c25-17-12-16-19(13-18(17)26)28-24(33)21(22(16)31)23(32)27-14-7-9-15(10-8-14)34-11-5-3-1-2-4-6-20(29)30/h7-10,12-13H,1-6,11H2,(H,27,32)(H,29,30)(H2,28,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111303 (8-{4-[(5-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinol...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3c(Cl)cccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H25ClN2O6/c25-17-7-6-8-18-20(17)22(30)21(24(32)27-18)23(31)26-15-10-12-16(13-11-15)33-14-5-3-1-2-4-9-19(28)29/h6-8,10-13H,1-5,9,14H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111277 (8-{4-[(4-Hydroxy-6-nitro-2-oxo-1,2-dihydro-quinoli...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(ccc3[nH]c2=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C24H25N3O8/c28-20(29)6-4-2-1-3-5-13-35-17-10-7-15(8-11-17)25-23(31)21-22(30)18-14-16(27(33)34)9-12-19(18)26-24(21)32/h7-12,14H,1-6,13H2,(H,25,31)(H,28,29)(H2,26,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111283 (8-(4-{[4-Hydroxy-1-(4-methoxy-phenyl)-2-oxo-2,5-di...) Show SMILES COc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C26H30N2O7/c1-34-20-14-10-19(11-15-20)28-17-22(29)24(26(28)33)25(32)27-18-8-12-21(13-9-18)35-16-6-4-2-3-5-7-23(30)31/h8-15,24H,2-7,16-17H2,1H3,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111304 (8-{4-[(4-Hydroxy-1-naphthalen-2-yl-2-oxo-2,5-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C29H30N2O6/c32-25-19-31(23-14-11-20-8-5-6-9-21(20)18-23)29(36)27(25)28(35)30-22-12-15-24(16-13-22)37-17-7-3-1-2-4-10-26(33)34/h5-6,8-9,11-16,18,27H,1-4,7,10,17,19H2,(H,30,35)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111312 (8-(4-{[4-Hydroxy-1-(4-nitro-phenyl)-2-oxo-2,5-dihy...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C25H27N3O8/c29-21-16-27(18-9-11-19(12-10-18)28(34)35)25(33)23(21)24(32)26-17-7-13-20(14-8-17)36-15-5-3-1-2-4-6-22(30)31/h7-14,23H,1-6,15-16H2,(H,26,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111300 (8-{4-[(5-Amino-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES Nc1cccc2[nH]c(=O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(O)c12 Show InChI InChI=1S/C24H27N3O6/c25-17-7-6-8-18-20(17)22(30)21(24(32)27-18)23(31)26-15-10-12-16(13-11-15)33-14-5-3-1-2-4-9-19(28)29/h6-8,10-13H,1-5,9,14,25H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111289 (8-{4-[(6-Fluoro-4-hydroxy-2-oxo-1,2-dihydro-quinol...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cc(F)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H25FN2O6/c25-15-7-12-19-18(14-15)22(30)21(24(32)27-19)23(31)26-16-8-10-17(11-9-16)33-13-5-3-1-2-4-6-20(28)29/h7-12,14H,1-6,13H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111274 (8-(4-(1-(4-chlorophenyl)-4-hydroxy-2-oxo-2,5-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C25H27ClN2O6/c26-17-7-11-19(12-8-17)28-16-21(29)23(25(28)33)24(32)27-18-9-13-20(14-10-18)34-15-5-3-1-2-4-6-22(30)31/h7-14,23H,1-6,15-16H2,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111318 (8-{4-[(4-Hydroxy-5-iodo-2-oxo-1,2-dihydro-quinolin...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3c(I)cccc3[nH]c2=O)cc1 Show InChI InChI=1S/C24H25IN2O6/c25-17-7-6-8-18-20(17)22(30)21(24(32)27-18)23(31)26-15-10-12-16(13-11-15)33-14-5-3-1-2-4-9-19(28)29/h6-8,10-13H,1-5,9,14H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111305 (8-{4-[(4-Hydroxy-5-nitro-2-oxo-1,2-dihydro-quinoli...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3c(cccc3[nH]c2=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C24H25N3O8/c28-19(29)9-4-2-1-3-5-14-35-16-12-10-15(11-13-16)25-23(31)21-22(30)20-17(26-24(21)32)7-6-8-18(20)27(33)34/h6-8,10-13H,1-5,9,14H2,(H,25,31)(H,28,29)(H2,26,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111276 (8-(4-{[1-(3,4-Dichloro-phenyl)-4-hydroxy-2-oxo-2,5...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C25H26Cl2N2O6/c26-19-12-9-17(14-20(19)27)29-15-21(30)23(25(29)34)24(33)28-16-7-10-18(11-8-16)35-13-5-3-1-2-4-6-22(31)32/h7-12,14,23H,1-6,13,15H2,(H,28,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111317 (3-{3-[4-(7-Carboxy-heptyloxy)-phenylcarbamoyl]-4-h...) Show SMILES COC(=O)c1cccc(c1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C27H30N2O8/c1-36-27(35)18-8-7-9-20(16-18)29-17-22(30)24(26(29)34)25(33)28-19-11-13-21(14-12-19)37-15-6-4-2-3-5-10-23(31)32/h7-9,11-14,16,24H,2-6,10,15,17H2,1H3,(H,28,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111310 (8-{4-[(6-Amino-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES Nc1ccc2[nH]c(=O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(O)c2c1 Show InChI InChI=1S/C24H27N3O6/c25-15-7-12-19-18(14-15)22(30)21(24(32)27-19)23(31)26-16-8-10-17(11-9-16)33-13-5-3-1-2-4-6-20(28)29/h7-12,14H,1-6,13,25H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111287 (8-{4-[(4-Hydroxy-2-oxo-1-phenyl-2,5-dihydro-1H-pyr...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H28N2O6/c28-21-17-27(19-9-5-4-6-10-19)25(32)23(21)24(31)26-18-12-14-20(15-13-18)33-16-8-3-1-2-7-11-22(29)30/h4-6,9-10,12-15,23H,1-3,7-8,11,16-17H2,(H,26,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111307 (8-(4-{[4-Hydroxy-8-(4-methoxy-phenyl)-2-oxo-1,2-di...) Show SMILES COc1ccc(cc1)-c1cccc2c(O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(=O)[nH]c12 Show InChI InChI=1S/C31H32N2O7/c1-39-22-15-11-20(12-16-22)24-8-7-9-25-28(24)33-31(38)27(29(25)36)30(37)32-21-13-17-23(18-14-21)40-19-6-4-2-3-5-10-26(34)35/h7-9,11-18H,2-6,10,19H2,1H3,(H,32,37)(H,34,35)(H2,33,36,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111272 (8-{4-[(7-Amino-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES Nc1ccc2c(O)c(C(=O)Nc3ccc(OCCCCCCCC(O)=O)cc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C24H27N3O6/c25-15-7-12-18-19(14-15)27-24(32)21(22(18)30)23(31)26-16-8-10-17(11-9-16)33-13-5-3-1-2-4-6-20(28)29/h7-12,14H,1-6,13,25H2,(H,26,31)(H,28,29)(H2,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111291 (8-{4-[(4-Hydroxy-2-oxo-5-phenyl-2,5-dihydro-1H-pyr...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)NC(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H28N2O6/c28-20(29)11-7-2-1-3-8-16-33-19-14-12-18(13-15-19)26-24(31)21-23(30)22(27-25(21)32)17-9-5-4-6-10-17/h4-6,9-10,12-15,21-22H,1-3,7-8,11,16H2,(H,26,31)(H,27,32)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111278 (8-{4-[(1-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-1H-pyr...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(Cc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C26H30N2O6/c29-22-18-28(17-19-9-5-4-6-10-19)26(33)24(22)25(32)27-20-12-14-21(15-13-20)34-16-8-3-1-2-7-11-23(30)31/h4-6,9-10,12-15,24H,1-3,7-8,11,16-18H2,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111290 (8-(4-{[4-Hydroxy-1-(4-morpholin-4-yl-phenyl)-2-oxo...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(cc2)N2CCOCC2)cc1 Show InChI InChI=1S/C29H35N3O7/c33-25-20-32(23-11-9-22(10-12-23)31-15-18-38-19-16-31)29(37)27(25)28(36)30-21-7-13-24(14-8-21)39-17-5-3-1-2-4-6-26(34)35/h7-14,27H,1-6,15-20H2,(H,30,36)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111293 (8-(4-{[4-Hydroxy-1-(2-methoxy-phenyl)-2-oxo-2,5-di...) Show SMILES COc1ccccc1N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C26H30N2O7/c1-34-22-10-7-6-9-20(22)28-17-21(29)24(26(28)33)25(32)27-18-12-14-19(15-13-18)35-16-8-4-2-3-5-11-23(30)31/h6-7,9-10,12-15,24H,2-5,8,11,16-17H2,1H3,(H,27,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111302 (8-(4-{[1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dih...) Show SMILES COC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)CN(C2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C26H29ClN2O6/c1-34-23(31)7-5-3-2-4-6-16-35-21-14-10-19(11-15-21)28-25(32)24-22(30)17-29(26(24)33)20-12-8-18(27)9-13-20/h8-15,24H,2-7,16-17H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111315 (8-(4-{[1-(4-Acetylamino-phenyl)-4-hydroxy-2-oxo-2,...) Show SMILES CC(=O)Nc1ccc(cc1)N1CC(=O)C(C(=O)Nc2ccc(OCCCCCCCC(O)=O)cc2)C1=O Show InChI InChI=1S/C27H31N3O7/c1-18(31)28-19-8-12-21(13-9-19)30-17-23(32)25(27(30)36)26(35)29-20-10-14-22(15-11-20)37-16-6-4-2-3-5-7-24(33)34/h8-15,25H,2-7,16-17H2,1H3,(H,28,31)(H,29,35)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111294 (8-(4-{[4-Hydroxy-5-(4-hydroxy-benzyl)-2-oxo-2,5-di...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)C2C(=O)NC(Cc3ccc(O)cc3)C2=O)cc1 Show InChI InChI=1S/C26H30N2O7/c29-19-11-7-17(8-12-19)16-21-24(32)23(26(34)28-21)25(33)27-18-9-13-20(14-10-18)35-15-5-3-1-2-4-6-22(30)31/h7-14,21,23,29H,1-6,15-16H2,(H,27,33)(H,28,34)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50111301 (8-{4-[(4-Hydroxy-8-naphthalen-1-yl-2-oxo-1,2-dihyd...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3cccc(-c4cccc5ccccc45)c3[nH]c2=O)cc1 Show InChI InChI=1S/C34H32N2O6/c37-29(38)16-4-2-1-3-7-21-42-24-19-17-23(18-20-24)35-33(40)30-32(39)28-15-9-14-27(31(28)36-34(30)41)26-13-8-11-22-10-5-6-12-25(22)26/h5-6,8-15,17-20H,1-4,7,16,21H2,(H,35,40)(H,37,38)(H2,36,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair

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