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Compile Data Set for Download or QSAR

Found 481 hits with Last Name = 'truchon' and Initial = 'jf'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134524
PNG
((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...)
Show SMILES Cc1cccc(\C=C\Cc2ccccc2\C=C\C(O)=O)c1OCc1ccccc1
Show InChI InChI=1S/C26H24O3/c1-20-9-7-15-24(26(20)29-19-21-10-3-2-4-11-21)16-8-14-22-12-5-6-13-23(22)17-18-25(27)28/h2-13,15-18H,14,19H2,1H3,(H,27,28)/b16-8+,18-17+
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7n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134516
PNG
(CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...)
Show SMILES O=C(CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C32H27NO4S2/c34-31(33-39(35,36)32-18-9-21-38-32)20-19-25-12-4-5-15-28(25)26-13-8-14-27(22-26)29-16-6-7-17-30(29)37-23-24-10-2-1-3-11-24/h1-18,21-22H,19-20,23H2,(H,33,34)
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16n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134522
PNG
(3-[2''-(2,6-Dichloro-benzyloxy)-[1,1';3',1'']terph...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1c(Cl)cccc1Cl
Show InChI InChI=1S/C28H22Cl2O3/c29-25-12-6-13-26(30)24(25)18-33-27-14-4-3-11-23(27)21-9-5-8-20(17-21)22-10-2-1-7-19(22)15-16-28(31)32/h1-14,17H,15-16,18H2,(H,31,32)
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21n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134519
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)15-14-20-10-4-5-11-22(20)21-16-25(30-18-21)23-12-6-7-13-24(23)29-17-19-8-2-1-3-9-19/h1-13,16,18H,14-15,17H2,(H,27,28)
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23n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50117689
PNG
(CHEMBL87371 | Thiophene-2-sulfonic acid [(E)-3-(3'...)
Show SMILES Clc1ccc(cc1Cl)-c1ccccc1\C=C\C(=O)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C19H13Cl2NO3S2/c20-16-9-7-14(12-17(16)21)15-5-2-1-4-13(15)8-10-18(23)22-27(24,25)19-6-3-11-26-19/h1-12H,(H,22,23)/b10-8+
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25n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134525
PNG
(3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1cc(cs1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)15-14-20-10-4-5-12-23(20)25-16-21(18-30-25)22-11-6-7-13-24(22)29-17-19-8-2-1-3-9-19/h1-13,16,18H,14-15,17H2,(H,27,28)
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27n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134517
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES CC(CC(O)=O)c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H24O3S/c1-19(15-27(28)29)22-11-5-6-12-23(22)21-16-26(31-18-21)24-13-7-8-14-25(24)30-17-20-9-3-2-4-10-20/h2-14,16,18-19H,15,17H2,1H3,(H,28,29)
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35n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134513
PNG
(CHEMBL124675 | {2-[5-(2-Benzyloxy-phenyl)-thiophen...)
Show SMILES OC(=O)CNc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C25H21NO3S/c27-25(28)15-26-22-12-6-4-10-20(22)19-14-24(30-17-19)21-11-5-7-13-23(21)29-16-18-8-2-1-3-9-18/h1-14,17,26H,15-16H2,(H,27,28)
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52n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134523
PNG
(3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-prop...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C28H24O3/c29-28(30)18-17-22-11-4-5-14-25(22)23-12-8-13-24(19-23)26-15-6-7-16-27(26)31-20-21-9-2-1-3-10-21/h1-16,19H,17-18,20H2,(H,29,30)
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55n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134521
PNG
((E)-3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-...)
Show SMILES OC(=O)\C=C\c1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C28H22O3/c29-28(30)18-17-22-11-4-5-14-25(22)23-12-8-13-24(19-23)26-15-6-7-16-27(26)31-20-21-9-2-1-3-10-21/h1-19H,20H2,(H,29,30)/b18-17+
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84n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134514
PNG
(3-(2-Phenoxymethyl-[1,1';3',1'']terphenyl-2''-yl)-...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1COc1ccccc1
Show InChI InChI=1S/C28H24O3/c29-28(30)18-17-21-9-4-6-15-26(21)22-11-8-12-23(19-22)27-16-7-5-10-24(27)20-31-25-13-2-1-3-14-25/h1-16,19H,17-18,20H2,(H,29,30)
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89n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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120n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of human DP receptor to PGD-2


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134515
PNG
(4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid | C...)
Show SMILES OC(=O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1
Show InChI InChI=1S/C23H22O3/c24-23(25)21-15-13-18(14-16-21)9-6-11-20-10-4-5-12-22(20)26-17-19-7-2-1-3-8-19/h1-5,7-8,10,12-16H,6,9,11,17H2,(H,24,25)
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150n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50134515
PNG
(4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid | C...)
Show SMILES OC(=O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1
Show InChI InChI=1S/C23H22O3/c24-23(25)21-15-13-18(14-16-21)9-6-11-20-10-4-5-12-22(20)26-17-19-7-2-1-3-8-19/h1-5,7-8,10,12-16H,6,9,11,17H2,(H,24,25)
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230n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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300n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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400n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Ability of the compound to inhibit the binding of human human Tthromboxane A2 receptor to TXA2


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134515
PNG
(4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid | C...)
Show SMILES OC(=O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1
Show InChI InChI=1S/C23H22O3/c24-23(25)21-15-13-18(14-16-21)9-6-11-20-10-4-5-12-22(20)26-17-19-7-2-1-3-8-19/h1-5,7-8,10,12-16H,6,9,11,17H2,(H,24,25)
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440n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134513
PNG
(CHEMBL124675 | {2-[5-(2-Benzyloxy-phenyl)-thiophen...)
Show SMILES OC(=O)CNc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C25H21NO3S/c27-25(28)15-26-22-12-6-4-10-20(22)19-14-24(30-17-19)21-11-5-7-13-23(21)29-16-18-8-2-1-3-9-18/h1-14,17,26H,15-16H2,(H,27,28)
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460n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134529
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1ccc(s1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)17-14-20-10-4-5-11-21(20)24-15-16-25(30-24)22-12-6-7-13-23(22)29-18-19-8-2-1-3-9-19/h1-13,15-16H,14,17-18H2,(H,27,28)
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520n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134518
PNG
(4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-buty...)
Show SMILES OC(=O)CCCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C29H26O3/c30-29(31)19-9-13-23-12-4-5-16-26(23)24-14-8-15-25(20-24)27-17-6-7-18-28(27)32-21-22-10-2-1-3-11-22/h1-8,10-12,14-18,20H,9,13,19,21H2,(H,30,31)
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590n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134528
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES CC(Cc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C27H24O3S/c1-19(27(28)29)15-21-11-5-6-12-23(21)22-16-26(31-18-22)24-13-7-8-14-25(24)30-17-20-9-3-2-4-10-20/h2-14,16,18-19H,15,17H2,1H3,(H,28,29)
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620n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134519
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)15-14-20-10-4-5-11-22(20)21-16-25(30-18-21)23-12-6-7-13-24(23)29-17-19-8-2-1-3-9-19/h1-13,16,18H,14-15,17H2,(H,27,28)
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650n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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710n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Ability of the compound to inhibit the binding of human human IP receptor to Prostaglandin I2 receptor


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134527
PNG
(3-[1,1';3',1'']Terphenyl-2-yl-propionic acid | CHE...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C21H18O2/c22-21(23)14-13-17-9-4-5-12-20(17)19-11-6-10-18(15-19)16-7-2-1-3-8-16/h1-12,15H,13-14H2,(H,22,23)
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750n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134525
PNG
(3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1cc(cs1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)15-14-20-10-4-5-12-23(20)25-16-21(18-30-25)22-11-6-7-13-24(22)29-17-19-8-2-1-3-9-19/h1-13,16,18H,14-15,17H2,(H,27,28)
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760n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134511
PNG
(3-(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-2-me...)
Show SMILES CC(Cc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H26O3/c1-21(29(30)31)18-23-12-5-6-15-26(23)24-13-9-14-25(19-24)27-16-7-8-17-28(27)32-20-22-10-3-2-4-11-22/h2-17,19,21H,18,20H2,1H3,(H,30,31)
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820n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134521
PNG
((E)-3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-...)
Show SMILES OC(=O)\C=C\c1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C28H22O3/c29-28(30)18-17-22-11-4-5-14-25(22)23-12-8-13-24(19-23)26-15-6-7-16-27(26)31-20-21-9-2-1-3-10-21/h1-19H,20H2,(H,29,30)/b18-17+
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830n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134528
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES CC(Cc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C27H24O3S/c1-19(27(28)29)15-21-11-5-6-12-23(21)22-16-26(31-18-22)24-13-7-8-14-25(24)30-17-20-9-3-2-4-10-20/h2-14,16,18-19H,15,17H2,1H3,(H,28,29)
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980n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134514
PNG
(3-(2-Phenoxymethyl-[1,1';3',1'']terphenyl-2''-yl)-...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1COc1ccccc1
Show InChI InChI=1S/C28H24O3/c29-28(30)18-17-21-9-4-6-15-26(21)22-11-8-12-23(19-22)27-16-7-5-10-24(27)20-31-25-13-2-1-3-14-25/h1-16,19H,17-18,20H2,(H,29,30)
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1.00E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134529
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1ccc(s1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)17-14-20-10-4-5-11-21(20)24-15-16-25(30-24)22-12-6-7-13-23(22)29-18-19-8-2-1-3-9-19/h1-13,15-16H,14,17-18H2,(H,27,28)
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1.10E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50134522
PNG
(3-[2''-(2,6-Dichloro-benzyloxy)-[1,1';3',1'']terph...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1c(Cl)cccc1Cl
Show InChI InChI=1S/C28H22Cl2O3/c29-25-12-6-13-26(30)24(25)18-33-27-14-4-3-11-23(27)21-9-5-8-20(17-21)22-10-2-1-7-19(22)15-16-28(31)32/h1-14,17H,15-16,18H2,(H,31,32)
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1.10E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134520
PNG
((2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-acetic...)
Show SMILES OC(=O)Cc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3/c28-27(29)18-23-11-4-5-14-24(23)21-12-8-13-22(17-21)25-15-6-7-16-26(25)30-19-20-9-2-1-3-10-20/h1-17H,18-19H2,(H,28,29)
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1.10E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134517
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES CC(CC(O)=O)c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H24O3S/c1-19(15-27(28)29)22-11-5-6-12-23(22)21-16-26(31-18-21)24-13-7-8-14-25(24)30-17-20-9-3-2-4-10-20/h2-14,16,18-19H,15,17H2,1H3,(H,28,29)
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1.10E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134522
PNG
(3-[2''-(2,6-Dichloro-benzyloxy)-[1,1';3',1'']terph...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1c(Cl)cccc1Cl
Show InChI InChI=1S/C28H22Cl2O3/c29-25-12-6-13-26(30)24(25)18-33-27-14-4-3-11-23(27)21-9-5-8-20(17-21)22-10-2-1-7-19(22)15-16-28(31)32/h1-14,17H,15-16,18H2,(H,31,32)
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1.10E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134511
PNG
(3-(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-2-me...)
Show SMILES CC(Cc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H26O3/c1-21(29(30)31)18-23-12-5-6-15-26(23)24-13-9-14-25(19-24)27-16-7-8-17-28(27)32-20-22-10-3-2-4-11-22/h2-17,19,21H,18,20H2,1H3,(H,30,31)
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1.20E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134510
PNG
(3-(4''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-prop...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C28H24O3/c29-28(30)18-15-23-9-4-5-12-27(23)25-11-6-10-24(19-25)22-13-16-26(17-14-22)31-20-21-7-2-1-3-8-21/h1-14,16-17,19H,15,18,20H2,(H,29,30)
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1.50E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134516
PNG
(CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...)
Show SMILES O=C(CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C32H27NO4S2/c34-31(33-39(35,36)32-18-9-21-38-32)20-19-25-12-4-5-15-28(25)26-13-8-14-27(22-26)29-16-6-7-17-30(29)37-23-24-10-2-1-3-11-24/h1-18,21-22H,19-20,23H2,(H,33,34)
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1.60E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134512
PNG
((E)-3-(3',4'-Dichloro-biphenyl-2-yl)-acrylic acid ...)
Show SMILES OC(=O)\C=C\c1ccccc1-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H10Cl2O2/c16-13-7-5-11(9-14(13)17)12-4-2-1-3-10(12)6-8-15(18)19/h1-9H,(H,18,19)/b8-6+
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1.60E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134516
PNG
(CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...)
Show SMILES O=C(CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C32H27NO4S2/c34-31(33-39(35,36)32-18-9-21-38-32)20-19-25-12-4-5-15-28(25)26-13-8-14-27(22-26)29-16-6-7-17-30(29)37-23-24-10-2-1-3-11-24/h1-18,21-22H,19-20,23H2,(H,33,34)
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1.70E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134521
PNG
((E)-3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-...)
Show SMILES OC(=O)\C=C\c1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C28H22O3/c29-28(30)18-17-22-11-4-5-14-25(22)23-12-8-13-24(19-23)26-15-6-7-16-27(26)31-20-21-9-2-1-3-10-21/h1-19H,20H2,(H,29,30)/b18-17+
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1.70E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134520
PNG
((2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-acetic...)
Show SMILES OC(=O)Cc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3/c28-27(29)18-23-11-4-5-14-24(23)21-12-8-13-22(17-21)25-15-6-7-16-26(25)30-19-20-9-2-1-3-10-20/h1-17H,18-19H2,(H,28,29)
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PubMed
1.70E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134523
PNG
(3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-prop...)
Show SMILES OC(=O)CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C28H24O3/c29-28(30)18-17-22-11-4-5-14-25(22)23-12-8-13-24(19-23)26-15-6-7-16-27(26)31-20-21-9-2-1-3-10-21/h1-16,19H,17-18,20H2,(H,29,30)
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PubMed
1.80E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134524
PNG
((E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-ally...)
Show SMILES Cc1cccc(\C=C\Cc2ccccc2\C=C\C(O)=O)c1OCc1ccccc1
Show InChI InChI=1S/C26H24O3/c1-20-9-7-15-24(26(20)29-19-21-10-3-2-4-11-21)16-8-14-22-12-5-6-13-23(22)17-18-25(27)28/h2-13,15-18H,14,19H2,1H3,(H,27,28)/b16-8+,18-17+
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1.90E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50134518
PNG
(4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-buty...)
Show SMILES OC(=O)CCCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C29H26O3/c30-29(31)19-9-13-23-12-4-5-16-26(23)24-14-8-15-25(20-24)27-17-6-7-18-28(27)32-21-22-10-2-1-3-11-22/h1-8,10-12,14-18,20H,9,13,19,21H2,(H,30,31)
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2.00E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50134515
PNG
(4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid | C...)
Show SMILES OC(=O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1
Show InChI InChI=1S/C23H22O3/c24-23(25)21-15-13-18(14-16-21)9-6-11-20-10-4-5-12-22(20)26-17-19-7-2-1-3-8-19/h1-5,7-8,10,12-16H,6,9,11,17H2,(H,24,25)
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PubMed
2.30E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134526
PNG
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
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2.30E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134513
PNG
(CHEMBL124675 | {2-[5-(2-Benzyloxy-phenyl)-thiophen...)
Show SMILES OC(=O)CNc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C25H21NO3S/c27-25(28)15-26-22-12-6-4-10-20(22)19-14-24(30-17-19)21-11-5-7-13-23(21)29-16-18-8-2-1-3-9-18/h1-14,17,26H,15-16H2,(H,27,28)
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2.50E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50134519
PNG
(3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Show SMILES OC(=O)CCc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C26H22O3S/c27-26(28)15-14-20-10-4-5-11-22(20)21-16-25(30-18-21)23-12-6-7-13-24(23)29-17-19-8-2-1-3-9-19/h1-13,16,18H,14-15,17H2,(H,27,28)
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2.50E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50134516
PNG
(CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...)
Show SMILES O=C(CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C32H27NO4S2/c34-31(33-39(35,36)32-18-9-21-38-32)20-19-25-12-4-5-15-28(25)26-13-8-14-27(22-26)29-16-6-7-17-30(29)37-23-24-10-2-1-3-11-24/h1-18,21-22H,19-20,23H2,(H,33,34)
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2.60E+3n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.


Bioorg Med Chem Lett 13: 3813-6 (2003)


BindingDB Entry DOI: 10.7270/Q26T0M1N
More data for this
Ligand-Target Pair
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