Found 235 hits with Last Name = 'waki' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM84928
(CAS_125368 | FK 1052 | NSC_125368)Show InChI InChI=1S/C18H19N3O/c1-11-14-5-3-4-6-17(14)21-16(11)8-7-13(18(21)22)9-15-12(2)19-10-20-15/h3-6,10,13H,7-9H2,1-2H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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MCE PC cid PC sid UniChem
Patents
| PubMed
| 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co., Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 265: 752-8 (1993)
BindingDB Entry DOI: 10.7270/Q2CV4G73 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM84928
(CAS_125368 | FK 1052 | NSC_125368)Show InChI InChI=1S/C18H19N3O/c1-11-14-5-3-4-6-17(14)21-16(11)8-7-13(18(21)22)9-15-12(2)19-10-20-15/h3-6,10,13H,7-9H2,1-2H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
| PubMed
| 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co., Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 265: 752-8 (1993)
BindingDB Entry DOI: 10.7270/Q2CV4G73 |
More data for this Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(GUINEA PIG) | BDBM50084033
(1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-pheny...)Show SMILES Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| Show InChI InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m0/s1 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co. Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 268: 571-5 (1994)
BindingDB Entry DOI: 10.7270/Q2WQ029S |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | Reactome pathway
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(GUINEA PIG) | BDBM21147
((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co. Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 268: 571-5 (1994)
BindingDB Entry DOI: 10.7270/Q2WQ029S |
More data for this Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(RAT) | BDBM50084033
(1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-pheny...)Show SMILES Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| Show InChI InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co. Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 268: 571-5 (1994)
BindingDB Entry DOI: 10.7270/Q2WQ029S |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(GUINEA PIG) | BDBM21147
((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| PubMed
| 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Co. Ltd.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 268: 571-5 (1994)
BindingDB Entry DOI: 10.7270/Q2WQ029S |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187752
(3-(1-(4-(piperidin-1-yl)butyl)piperidin-4-yl)-1H-i...)Show InChI InChI=1S/C22H33N3/c1-4-12-24(13-5-1)14-6-7-15-25-16-10-19(11-17-25)21-18-23-22-9-3-2-8-20(21)22/h2-3,8-9,18-19,23H,1,4-7,10-17H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115121
(CHEMBL3609359)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCc2ccccc2C1 Show InChI InChI=1S/C25H31N3/c1-2-7-22-19-28(17-10-20(22)6-1)14-5-13-27-15-11-21(12-16-27)24-18-26-25-9-4-3-8-23(24)25/h1-4,6-9,18,21,26H,5,10-17,19H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115118
(CHEMBL3609357)Show SMILES C(CN1Cc2ccccc2C1)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-2-7-21-18-27(17-20(21)6-1)13-5-12-26-14-10-19(11-15-26)23-16-25-24-9-4-3-8-22(23)24/h1-4,6-9,16,19,25H,5,10-15,17-18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115188
(CHEMBL3609353)Show InChI InChI=1S/C18H27N3/c1-20(2)10-5-11-21-12-8-15(9-13-21)17-14-19-18-7-4-3-6-16(17)18/h3-4,6-7,14-15,19H,5,8-13H2,1-2H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115120
(CHEMBL3609358)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C27H35N3/c1-2-7-22(8-3-1)23-11-17-29(18-12-23)15-6-16-30-19-13-24(14-20-30)26-21-28-27-10-5-4-9-25(26)27/h1-5,7-10,21,23-24,28H,6,11-20H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115123
(CHEMBL3609354)Show SMILES O=C1N(CCCN2CCC(CC2)c2c[nH]c3ccccc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H25N3O2/c28-23-19-7-1-2-8-20(19)24(29)27(23)13-5-12-26-14-10-17(11-15-26)21-16-25-22-9-4-3-6-18(21)22/h1-4,6-9,16-17,25H,5,10-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115114
(CHEMBL3609356)Show SMILES C(CN1CCc2ccccc12)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-4-9-24-20(6-1)12-17-27(24)14-5-13-26-15-10-19(11-16-26)22-18-25-23-8-3-2-7-21(22)23/h1-4,6-9,18-19,25H,5,10-17H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187757
(1-(3-(4-(benzofuran-3-yl)piperidin-1-yl)propyl)pip...)Show InChI InChI=1S/C21H30N2O/c1-4-11-22(12-5-1)13-6-14-23-15-9-18(10-16-23)20-17-24-21-8-3-2-7-19(20)21/h2-3,7-8,17-18H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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| Article PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against Acetylcholinesterase |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against Acetylcholinesterase |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115113
(CHEMBL3609355)Show InChI InChI=1S/C20H25N3/c1-2-7-20-18(6-1)19(16-21-20)17-8-14-23(15-9-17)13-5-12-22-10-3-4-11-22/h1-4,6-7,10-11,16-17,21H,5,8-9,12-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115190
(CHEMBL3609351)Show InChI InChI=1S/C22H26N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h1-5,7-8,10-11,17,19,23H,6,9,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187754
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)benz...)Show InChI InChI=1S/C20H29N3O/c1-4-11-22(12-5-1)13-6-14-23-15-9-17(10-16-23)20-18-7-2-3-8-19(18)24-21-20/h2-3,7-8,17H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187748
(5-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-21-19(15-18)20(16-23-21)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115190
(CHEMBL3609351)Show InChI InChI=1S/C22H26N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h1-5,7-8,10-11,17,19,23H,6,9,12-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha1D adrenoceptor |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| 17.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-1) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-1) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50029941
(2-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,6-dimethox...)Show SMILES COc1cc2CC(CCC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC Show InChI InChI=1S/C25H31NO3/c1-28-23-15-21-14-20(25(27)22(21)16-24(23)29-2)9-8-18-10-12-26(13-11-18)17-19-6-4-3-5-7-19/h3-7,15-16,18,20H,8-14,17H2,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-1) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic Alpha-1D receptor |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50029941
(2-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,6-dimethox...)Show SMILES COc1cc2CC(CCC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC Show InChI InChI=1S/C25H31NO3/c1-28-23-15-21-14-20(25(27)22(21)16-24(23)29-2)9-8-18-10-12-26(13-11-18)17-19-6-4-3-5-7-19/h3-7,15-16,18,20H,8-14,17H2,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against Acetylcholinesterase |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic Alpha-1D receptor |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| 37.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-2) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50422179
(CHEMBL2093912)Show SMILES COc1cc2C[C@H](CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |r| Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-2) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50029941
(2-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,6-dimethox...)Show SMILES COc1cc2CC(CCC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC Show InChI InChI=1S/C25H31NO3/c1-28-23-15-21-14-20(25(27)22(21)16-24(23)29-2)9-8-18-10-12-26(13-11-18)17-19-6-4-3-5-7-19/h3-7,15-16,18,20H,8-14,17H2,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-2) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115189
(CHEMBL3609352)Show InChI InChI=1S/C22H32N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h4-5,10-11,17-19,23H,1-3,6-9,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115118
(CHEMBL3609357)Show SMILES C(CN1Cc2ccccc2C1)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-2-7-21-18-27(17-20(21)6-1)13-5-12-26-14-10-19(11-15-26)23-16-25-24-9-4-3-8-22(23)24/h1-4,6-9,16,19,25H,5,10-15,17-18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115114
(CHEMBL3609356)Show SMILES C(CN1CCc2ccccc12)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-4-9-24-20(6-1)12-17-27(24)14-5-13-26-15-10-19(11-16-26)22-18-25-23-8-3-2-7-21(22)23/h1-4,6-9,18-19,25H,5,10-17H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115123
(CHEMBL3609354)Show SMILES O=C1N(CCCN2CCC(CC2)c2c[nH]c3ccccc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H25N3O2/c28-23-19-7-1-2-8-20(19)24(29)27(23)13-5-12-26-14-10-17(11-15-26)21-16-25-22-9-4-3-6-18(21)22/h1-4,6-9,16-17,25H,5,10-15H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50029912
(2-(1-Benzyl-piperidin-4-yl)-5,6-dimethoxy-indan-1-...)Show InChI InChI=1S/C23H27NO3/c1-26-21-13-18-12-19(23(25)20(18)14-22(21)27-2)17-8-10-24(11-9-17)15-16-6-4-3-5-7-16/h3-7,13-14,17,19H,8-12,15H2,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against Acetylcholinesterase |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...) | BDBM50029912
(2-(1-Benzyl-piperidin-4-yl)-5,6-dimethoxy-indan-1-...)Show InChI InChI=1S/C23H27NO3/c1-26-21-13-18-12-19(23(25)20(18)14-22(21)27-2)17-8-10-24(11-9-17)15-16-6-4-3-5-7-16/h3-7,13-14,17,19H,8-12,15H2,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity was calculated for the model Acetylcholinesterase (Expt-2) |
J Med Chem 39: 4460-70 (1996)
Article DOI: 10.1021/jm950596e BindingDB Entry DOI: 10.7270/Q2HD7WB9 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187752
(3-(1-(4-(piperidin-1-yl)butyl)piperidin-4-yl)-1H-i...)Show InChI InChI=1S/C22H33N3/c1-4-12-24(13-5-1)14-6-7-15-25-16-10-19(11-17-25)21-18-23-22-9-3-2-8-20(21)22/h2-3,8-9,18-19,23H,1,4-7,10-17H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187754
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)benz...)Show InChI InChI=1S/C20H29N3O/c1-4-11-22(12-5-1)13-6-14-23-15-9-17(10-16-23)20-18-7-2-3-8-19(18)24-21-20/h2-3,7-8,17H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187757
(1-(3-(4-(benzofuran-3-yl)piperidin-1-yl)propyl)pip...)Show InChI InChI=1S/C21H30N2O/c1-4-11-22(12-5-1)13-6-14-23-15-9-18(10-16-23)20-17-24-21-8-3-2-7-19(20)21/h2-3,7-8,17-18H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |