Compile Data Set for Download or QSAR

Found 46 hits with Last Name = 'wolfangel' and Initial = 'cd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3354 (2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...) Show SMILES CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2Se2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3361 ((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...) Show SMILES N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3362 ((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...) Show SMILES N[C@@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3351 (2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl...) Show SMILES NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3352 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc12 Show InChI InChI=1S/C28H32N2O4Se2/c1-27(2,3)33-25(31)21-17-13-9-11-15-19(17)29(7)23(21)35-36-24-22(26(32)34-28(4,5)6)18-14-10-12-16-20(18)30(24)8/h9-16H,1-8H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3358 (1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...) Show SMILES CCN(CC)CCn1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2CCN(CC)CC)c(C(=O)NC)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-35(8-2)19-21-37-25-17-13-11-15-23(25)27(29(39)33-5)31(37)41-42-32-28(30(40)34-6)24-16-12-14-18-26(24)38(32)22-20-36(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3355 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1-methy...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2c(C(=O)NCCN(CC)CC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-37(8-2)21-19-33-29(39)27-23-15-11-13-17-25(23)35(5)31(27)41-42-32-28(24-16-12-14-18-26(24)36(32)6)30(40)34-20-22-38(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3361 ((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...) Show SMILES N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3353 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12 Show InChI InChI=1S/C20H16N2O4Se2/c1-21-13-9-5-3-7-11(13)15(19(23)24)17(21)27-28-18-16(20(25)26)12-8-4-6-10-14(12)22(18)2/h3-10H,1-2H3,(H,23,24)(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3356 (2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...) Show SMILES CNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NC)[nH]c2ccccc12 Show InChI InChI=1S/C20H18N4O2Se2/c1-21-17(25)15-11-7-3-5-9-13(11)23-19(15)27-28-20-16(18(26)22-2)12-8-4-6-10-14(12)24-20/h3-10,23-24H,1-2H3,(H,21,25)(H,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3355 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1-methy...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2c(C(=O)NCCN(CC)CC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-37(8-2)21-19-33-29(39)27-23-15-11-13-17-25(23)35(5)31(27)41-42-32-28(24-16-12-14-18-26(24)36(32)6)30(40)34-20-22-38(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3353 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12 Show InChI InChI=1S/C20H16N2O4Se2/c1-21-13-9-5-3-7-11(13)15(19(23)24)17(21)27-28-18-16(20(25)26)12-8-4-6-10-14(12)22(18)2/h3-10H,1-2H3,(H,23,24)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3357 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1H-indo...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NCCN(CC)CC)[nH]c2ccccc12 Show InChI InChI=1S/C30H40N6O2Se2/c1-5-35(6-2)19-17-31-27(37)25-21-13-9-11-15-23(21)33-29(25)39-40-30-26(22-14-10-12-16-24(22)34-30)28(38)32-18-20-36(7-3)8-4/h9-16,33-34H,5-8,17-20H2,1-4H3,(H,31,37)(H,32,38)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Binding affinity to 5-HT1A receptor (unknown origin) by radioligand displacement assay				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3362 ((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...) Show SMILES N[C@@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3357 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1H-indo...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NCCN(CC)CC)[nH]c2ccccc12 Show InChI InChI=1S/C30H40N6O2Se2/c1-5-35(6-2)19-17-31-27(37)25-21-13-9-11-15-23(21)33-29(25)39-40-30-26(22-14-10-12-16-24(22)34-30)28(38)32-18-20-36(7-3)8-4/h9-16,33-34H,5-8,17-20H2,1-4H3,(H,31,37)(H,32,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3355 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1-methy...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2c(C(=O)NCCN(CC)CC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-37(8-2)21-19-33-29(39)27-23-15-11-13-17-25(23)35(5)31(27)41-42-32-28(24-16-12-14-18-26(24)36(32)6)30(40)34-20-22-38(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3354 (2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...) Show SMILES CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2Se2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3354 (2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...) Show SMILES CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2Se2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3360 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3350 (CHEMBL342929 | N,1-dimethyl-2-{[1-methyl-3-(methyl...) Show SMILES CNC(=O)c1c(SSc2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2S2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3358 (1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...) Show SMILES CCN(CC)CCn1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2CCN(CC)CC)c(C(=O)NC)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-35(8-2)19-21-37-25-17-13-11-15-23(25)27(29(39)33-5)31(37)41-42-32-28(30(40)34-6)24-16-12-14-18-26(24)38(32)22-20-36(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3350 (CHEMBL342929 | N,1-dimethyl-2-{[1-methyl-3-(methyl...) Show SMILES CNC(=O)c1c(SSc2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2S2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3360 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3351 (2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl...) Show SMILES NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3356 (2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...) Show SMILES CNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NC)[nH]c2ccccc12 Show InChI InChI=1S/C20H18N4O2Se2/c1-21-17(25)15-11-7-3-5-9-13(11)23-19(15)27-28-20-16(18(26)22-2)12-8-4-6-10-14(12)24-20/h3-10,23-24H,1-2H3,(H,21,25)(H,22,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3357 (2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1H-indo...) Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NCCN(CC)CC)[nH]c2ccccc12 Show InChI InChI=1S/C30H40N6O2Se2/c1-5-35(6-2)19-17-31-27(37)25-21-13-9-11-15-23(21)33-29(25)39-40-30-26(22-14-10-12-16-24(22)34-30)28(38)32-18-20-36(7-3)8-4/h9-16,33-34H,5-8,17-20H2,1-4H3,(H,31,37)(H,32,38)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3356 (2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...) Show SMILES CNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NC)[nH]c2ccccc12 Show InChI InChI=1S/C20H18N4O2Se2/c1-21-17(25)15-11-7-3-5-9-13(11)23-19(15)27-28-20-16(18(26)22-2)12-8-4-6-10-14(12)24-20/h3-10,23-24H,1-2H3,(H,21,25)(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3361 ((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...) Show SMILES N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3353 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12 Show InChI InChI=1S/C20H16N2O4Se2/c1-21-13-9-5-3-7-11(13)15(19(23)24)17(21)27-28-18-16(20(25)26)12-8-4-6-10-14(12)22(18)2/h3-10H,1-2H3,(H,23,24)(H,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3362 ((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...) Show SMILES N[C@@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3350 (CHEMBL342929 | N,1-dimethyl-2-{[1-methyl-3-(methyl...) Show SMILES CNC(=O)c1c(SSc2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12 Show InChI InChI=1S/C22H22N4O2S2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3352 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc12 Show InChI InChI=1S/C28H32N2O4Se2/c1-27(2,3)33-25(31)21-17-13-9-11-15-19(17)29(7)23(21)35-36-24-22(26(32)34-28(4,5)6)18-14-10-12-16-20(18)30(24)8/h9-16H,1-8H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.10E+4	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM3359 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3359 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3358 (1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...) Show SMILES CCN(CC)CCn1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2CCN(CC)CC)c(C(=O)NC)c2ccccc12 Show InChI InChI=1S/C32H44N6O2Se2/c1-7-35(8-2)19-21-37-25-17-13-11-15-23(25)27(29(39)33-5)31(37)41-42-32-28(30(40)34-6)24-16-12-14-18-26(24)38(32)22-20-36(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3359 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM3360 ((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...) Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H34F6N6O4Se2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3352 (2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...) Show SMILES Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc12 Show InChI InChI=1S/C28H32N2O4Se2/c1-27(2,3)33-25(31)21-17-13-9-11-15-19(17)29(7)23(21)35-36-24-22(26(32)34-28(4,5)6)18-14-10-12-16-20(18)30(24)8/h9-16H,1-8H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	22
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 413-26 (1997) Article DOI: 10.1021/jm960689b BindingDB Entry DOI: 10.7270/Q2TH8JWJ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50509149 (CHEMBL3421836) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C23H27Cl2NO3/c1-14-17-7-4-6-15(12-23(2,3)29)18(17)10-16(13-27)26(14)22(28)11-19-20(24)8-5-9-21(19)25/h4-9,14,16,27,29H,10-13H2,1-3H3/t14-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human D5 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50509151 (CHEMBL3421730) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2C(C)(C)O)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C22H25Cl2NO3/c1-13-15-6-4-7-18(22(2,3)28)16(15)10-14(12-26)25(13)21(27)11-17-19(23)8-5-9-20(17)24/h4-9,13-14,26,28H,10-12H2,1-3H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Agonist activity at human D1 receptor stably expressed in HEK293 cells assessed as induction of cAMP accumulation incubated for 60 mins by HTRF assay				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human D1 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (Mus musculus (Mouse))	BDBM50509150 (LY-3154207 | Ly3154207 | Mevidalen) Show SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C24H29Cl2NO3/c1-15-18-7-4-6-16(10-11-24(2,3)30)19(18)12-17(14-28)27(15)23(29)13-20-21(25)8-5-9-22(20)26/h4-9,15,17,28,30H,10-14H2,1-3H3/t15-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
AMRI UK Ltd Curated by ChEMBL					Assay Description Positive allosteric modulator activity at mouse D1 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...				J Med Chem 62: 8711-8732 (2019) Article DOI: 10.1021/acs.jmedchem.9b01234 BindingDB Entry DOI: 10.7270/Q2CC140V
					More data for this Ligand-Target Pair				3D Structure (crystal)