BindingDB PrimarySearch

Found 26 hits with Last Name = 'yajima' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082324 ((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082323 (4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride				J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD
Suntory Biomedical Research Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082320 (4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50082322 (1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 4 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50091592 (7-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride				J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD
Suntory Biomedical Research Limited Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082320 (4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082323 (4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 14 (Homo sapiens (Human))	BDBM50437694 (CHEMBL1410015) Show SMILES Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP14				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082324 ((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50082322 (1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes				Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50091591 ((2S)-1-(4-amino-2,3,5-trimethylphenoxy)-3-{4-[4-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride				J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD
Suntory Biomedical Research Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human UCH-L1 using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair