Found 44 hits with Last Name = 'zhao' and Initial = 'wm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069691
(Xanthoangelol | Xanthoangerol)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)\[#6]=[#6]\c2ccccc2)c1-[#8] Show InChI InChI=1S/C25H28O3/c1-18(2)8-7-9-19(3)12-14-21-24(27)17-15-22(25(21)28)23(26)16-13-20-10-5-4-6-11-20/h4-6,8,10-13,15-17,27-28H,7,9,14H2,1-3H3/b16-13+,19-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of FGFR1 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50263015
(CHEMBL478611 | epihematoxylol)Show SMILES O[C@@H]1c2ccc(O)c(O)c2OC[C@]1(O)Cc1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C16H16O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,15,17-22H,6-7H2/t15-,16-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Met (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50263015
(CHEMBL478611 | epihematoxylol)Show SMILES O[C@@H]1c2ccc(O)c(O)c2OC[C@]1(O)Cc1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C16H16O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,15,17-22H,6-7H2/t15-,16-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Src (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Met (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Src (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50036268
(CHEMBL3359316)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)=C)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@H](CO)CCC(=C)C(C)C |r| Show InChI InChI=1S/C31H50O3/c1-20(2)22(5)8-9-23(18-32)25-12-14-29(7)26-11-10-24(21(3)4)30(15-13-27(33)34)19-31(26,30)17-16-28(25,29)6/h20,23-26,32H,3,5,8-19H2,1-2,4,6-7H3,(H,33,34)/t23-,24-,25+,26-,28+,29-,30+,31-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of mouse 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50263015
(CHEMBL478611 | epihematoxylol)Show SMILES O[C@@H]1c2ccc(O)c(O)c2OC[C@]1(O)Cc1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C16H16O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,15,17-22H,6-7H2/t15-,16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of FGFR1 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50263016
(CHEMBL477560 | hematoxylene)Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of FGFR1 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50263015
(CHEMBL478611 | epihematoxylol)Show SMILES O[C@@H]1c2ccc(O)c(O)c2OC[C@]1(O)Cc1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C16H16O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,15,17-22H,6-7H2/t15-,16-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of cKit (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50263016
(CHEMBL477560 | hematoxylene)Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Met (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50263017
(CHEMBL477768 | hematoxylone)Show SMILES Oc1ccc(C[C@@]2(O)COc3c(O)c(O)ccc3C2=O)cc1O |r| Show InChI InChI=1S/C16H14O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,17-20,22H,6-7H2/t16-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Met (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of ErbB2 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50036268
(CHEMBL3359316)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)=C)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@H](CO)CCC(=C)C(C)C |r| Show InChI InChI=1S/C31H50O3/c1-20(2)22(5)8-9-23(18-32)25-12-14-29(7)26-11-10-24(21(3)4)30(15-13-27(33)34)19-31(26,30)17-16-28(25,29)6/h20,23-26,32H,3,5,8-19H2,1-2,4,6-7H3,(H,33,34)/t23-,24-,25+,26-,28+,29-,30+,31-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50263016
(CHEMBL477560 | hematoxylene)Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Src (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50263017
(CHEMBL477768 | hematoxylone)Show SMILES Oc1ccc(C[C@@]2(O)COc3c(O)c(O)ccc3C2=O)cc1O |r| Show InChI InChI=1S/C16H14O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,17-20,22H,6-7H2/t16-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of c-Src (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50263015
(CHEMBL478611 | epihematoxylol)Show SMILES O[C@@H]1c2ccc(O)c(O)c2OC[C@]1(O)Cc1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C16H16O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,15,17-22H,6-7H2/t15-,16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50036269
(CHEMBL3359319)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@]5(C[C@@]35CC[C@]12C)CCC(=O)C4(C)C)[C@@H](CCC(=C)C(C)C)C(O)=O |r| Show InChI InChI=1S/C31H48O3/c1-19(2)20(3)8-9-21(26(33)34)22-12-14-29(7)24-11-10-23-27(4,5)25(32)13-15-30(23)18-31(24,30)17-16-28(22,29)6/h19,21-24H,3,8-18H2,1-2,4-7H3,(H,33,34)/t21-,22-,23+,24+,28-,29+,30-,31+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069688
(CHEMBL3402548)Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)cc2)c(O)c1CC(=O)C(C)=C Show InChI InChI=1S/C21H20O5/c1-13(2)19(24)12-17-20(26-3)11-9-16(21(17)25)18(23)10-6-14-4-7-15(22)8-5-14/h4-11,22,25H,1,12H2,2-3H3/b10-6+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of cKit (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50036250
(CHEMBL3359317)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)=C)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@@H](CCC(=C)C(C)C)COC(C)=O |r| Show InChI InChI=1S/C33H52O4/c1-21(2)23(5)9-10-25(19-37-24(6)34)27-13-15-31(8)28-12-11-26(22(3)4)32(16-14-29(35)36)20-33(28,32)18-17-30(27,31)7/h21,25-28H,3,5,9-20H2,1-2,4,6-8H3,(H,35,36)/t25-,26-,27+,28-,30+,31-,32+,33-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of mouse 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50263017
(CHEMBL477768 | hematoxylone)Show SMILES Oc1ccc(C[C@@]2(O)COc3c(O)c(O)ccc3C2=O)cc1O |r| Show InChI InChI=1S/C16H14O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,17-20,22H,6-7H2/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of FGFR1 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of Flt1 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50263017
(CHEMBL477768 | hematoxylone)Show SMILES Oc1ccc(C[C@@]2(O)COc3c(O)c(O)ccc3C2=O)cc1O |r| Show InChI InChI=1S/C16H14O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,17-20,22H,6-7H2/t16-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of cKit (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of EGFR (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50036246
(CHEMBL3359318)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)(C)O)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@@H](CCC(=C)C(C)C)COC(C)=O |r| Show InChI InChI=1S/C33H54O5/c1-21(2)22(3)9-10-24(19-38-23(4)34)25-13-15-31(8)27-12-11-26(29(5,6)37)32(16-14-28(35)36)20-33(27,32)18-17-30(25,31)7/h21,24-27,37H,3,9-20H2,1-2,4-8H3,(H,35,36)/t24-,25+,26-,27-,30+,31-,32+,33-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069683
(CHEMBL1718454)Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)cc2)c(O)c1CC(OO)C(C)=C Show InChI InChI=1S/C21H22O6/c1-13(2)20(27-25)12-17-19(26-3)11-9-16(21(17)24)18(23)10-6-14-4-7-15(22)8-5-14/h4-11,20,22,24-25H,1,12H2,2-3H3/b10-6+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50352811
(CHEMBL1722838)Show SMILES [#6]-[#8]-c1ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2)c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6] Show InChI InChI=1S/C26H30O4/c1-18(2)6-5-7-19(3)8-14-23-25(30-4)17-15-22(26(23)29)24(28)16-11-20-9-12-21(27)13-10-20/h6,8-13,15-17,27,29H,5,7,14H2,1-4H3/b16-11+,19-8+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50036250
(CHEMBL3359317)Show SMILES [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)=C)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@@H](CCC(=C)C(C)C)COC(C)=O |r| Show InChI InChI=1S/C33H52O4/c1-21(2)23(5)9-10-25(19-37-24(6)34)27-13-15-31(8)28-12-11-26(22(3)4)32(16-14-29(35)36)20-33(28,32)18-17-30(27,31)7/h21,25-28H,3,5,9-20H2,1-2,4,6-8H3,(H,35,36)/t25-,26-,27+,28-,30+,31-,32+,33-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 in expressed in HEK293 cells microsomal fractions incubated with NADPH and [3H]-cortisone by scintillation proximity ... |
Bioorg Med Chem Lett 24: 5395-8 (2015)
Article DOI: 10.1016/j.bmcl.2014.10.036 BindingDB Entry DOI: 10.7270/Q2V989P6 |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50263016
(CHEMBL477560 | hematoxylene)Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of cKit (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50263017
(CHEMBL477768 | hematoxylone)Show SMILES Oc1ccc(C[C@@]2(O)COc3c(O)c(O)ccc3C2=O)cc1O |r| Show InChI InChI=1S/C16H14O7/c17-10-3-1-8(5-12(10)19)6-16(22)7-23-14-9(15(16)21)2-4-11(18)13(14)20/h1-5,17-20,22H,6-7H2/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50352809
(CHEMBL458094)Show SMILES [#6]-[#8]-c1ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2)c(-[#8])c1-[#6]\[#6]=[#6](\[#6])-[#6] Show InChI InChI=1S/C21H22O4/c1-14(2)4-10-18-20(25-3)13-11-17(21(18)24)19(23)12-7-15-5-8-16(22)9-6-15/h4-9,11-13,22,24H,10H2,1-3H3/b12-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50263016
(CHEMBL477560 | hematoxylene)Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Ephrin type-B receptor 2
(Homo sapiens (Human)) | BDBM50263183
((+)-haematoxylin | (+)-hematoxylin | (6aS,11bR)-7,...)Show SMILES Oc1ccc2[C@H]3c4cc(O)c(O)cc4C[C@@]3(O)COc2c1O |r| Show InChI InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica
Curated by ChEMBL
| Assay Description Inhibition of EphB2 (unknown origin) by ELISA |
J Med Chem 51: 4419-29 (2008)
Article DOI: 10.1021/jm701501x BindingDB Entry DOI: 10.7270/Q2N879MQ |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069689
(CHEMBL3402550)Show SMILES CCOC1C(Oc2c1c(OC)ccc2C(=O)\C=C\c1ccc(O)cc1)C(C)(C)O Show InChI InChI=1S/C23H26O6/c1-5-28-21-19-18(27-4)13-11-16(20(19)29-22(21)23(2,3)26)17(25)12-8-14-6-9-15(24)10-7-14/h6-13,21-22,24,26H,5H2,1-4H3/b12-8+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50352810
(CHEMBL1711961)Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)cc2)c(O)c1CC(O)C(C)=C Show InChI InChI=1S/C21H22O5/c1-13(2)19(24)12-17-20(26-3)11-9-16(21(17)25)18(23)10-6-14-4-7-15(22)8-5-14/h4-11,19,22,24-25H,1,12H2,2-3H3/b10-6+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50067880
(4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one | 4-me...)Show InChI InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069686
(CHEMBL3402554)Show SMILES CC(C)C(=O)O[C@H]1Cc2c(OC1(C)C)ccc1ccc(=O)oc21 |r| Show InChI InChI=1S/C18H20O5/c1-10(2)17(20)21-14-9-12-13(23-18(14,3)4)7-5-11-6-8-15(19)22-16(11)12/h5-8,10,14H,9H2,1-4H3/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50071370
((3R,8S)-falcarindiol | (3R,8S,)-heptadeca-1,9-dien...)Show InChI InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069685
(Jatamansin)Show SMILES C\C=C(\C)C(=O)O[C@@H]1Cc2c(OC1(C)C)ccc1ccc(=O)oc21 |r| Show InChI InChI=1S/C19H20O5/c1-5-11(2)18(21)22-15-10-13-14(24-19(15,3)4)8-6-12-7-9-16(20)23-17(12)13/h5-9,15H,10H2,1-4H3/b11-5-/t15-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50056315
(CHEBI:17558 | Quercitrin)Show SMILES C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-26,28-29H,1H3/t7-,15-,17+,18+,21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50069687
((+)-Cis-Khellactone | CHEMBL68727)Show SMILES CC1(C)Oc2ccc3ccc(=O)oc3c2[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C14H14O5/c1-14(2)13(17)11(16)10-8(19-14)5-3-7-4-6-9(15)18-12(7)10/h3-6,11,13,16-17H,1-2H3/t11-,13-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay |
Bioorg Med Chem Lett 25: 2028-32 (2015)
Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3 |
More data for this Ligand-Target Pair | |