Found 76 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine receptor A1
(BOVINE) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Mus musculus (Mouse)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assay |
J Med Chem 61: 8299-8320 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00838
BindingDB Entry DOI: 10.7270/Q2QF8WH4 |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assay |
J Med Chem 61: 8299-8320 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00838
BindingDB Entry DOI: 10.7270/Q2QF8WH4 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of urokinase |
J Med Chem 52: 3159-65 (2009)
Article DOI: 10.1021/jm801444x
BindingDB Entry DOI: 10.7270/Q2FF3TM8 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description
Binding affinity for HA-tagged mutant human Adenosine A2A receptor (H250N) using [3H]-CGS-21,680 as radioligand expressed in COS-7 cells |
J Med Chem 40: 2588-95 (1997)
Article DOI: 10.1021/jm970084v
BindingDB Entry DOI: 10.7270/Q27M08MC |
More data for this
Ligand-Target Pair | |
Solute carrier family 22 member 2
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description
TP_TRANSPORTER: inhibition of TEA uptake in OCT2-expressing MDCK cells |
Pharm Res 18: 1528-34 (2001)
BindingDB Entry DOI: 10.7270/Q28G8N0T |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| 5.30E+3 | -30.1 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Max-Planck-Institut fuer Biochemie
| Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t... |
J Mol Biol 301: 465-75 (2000)
Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Solute carrier family 22 member 1
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description
TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing MDCK cells |
Pharm Res 18: 1528-34 (2001)
BindingDB Entry DOI: 10.7270/Q28G8N0T |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of uPA (unknown origin) using L-pyroglutamyl-glycyl-L-arginine-p-nitro-anilide as susbtrate by Lineweaver-Burk plot analysis |
J Med Chem 61: 8299-8320 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00838
BindingDB Entry DOI: 10.7270/Q2QF8WH4 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of uPA (unknown origin) using L-pyroglutamyl-glycyl-L-arginine-p-nitroanilide as substrate by Lineweaver-Burk plot analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01423
BindingDB Entry DOI: 10.7270/Q2639TNC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Voltage-dependent calcium channel gamma-1 subunit
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Calcium release-activated calcium channel protein 1
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
D(1A) dopamine receptor
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Glycine amidinotransferase, mitochondrial
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Protachykinin-1
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Pro-thyrotropin-releasing hormone
(RAT) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(PIG) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Rattus norvegicus (Rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound against porcine kidney amine oxidase |
Bioorg Med Chem Lett 11: 2565-8 (2001)
BindingDB Entry DOI: 10.7270/Q25T3JR2 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine 1D receptor
(Bos taurus (Bovine)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Center for Bio-Pharmaceutical Sciences
Curated by PDSP Ki Database
| |
J Recept Res 11: 891-907 (1991)
Article DOI: 10.3109/10799899109064686
BindingDB Entry DOI: 10.7270/Q2TH8K5J |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description
Binding affinity for HA-tagged mutant human Adenosine A2A receptor (V84L), using [3H]CGS-21680 as radioligand expressed in COS-7 cells |
J Med Chem 40: 2588-95 (1997)
Article DOI: 10.1021/jm970084v
BindingDB Entry DOI: 10.7270/Q27M08MC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description
Binding affinity for HA-tagged wild type human Adenosine A2A receptor (WT) using [3H]CGS-21680 as radioligand expressed in COS-7 cells |
J Med Chem 40: 2588-95 (1997)
Article DOI: 10.1021/jm970084v
BindingDB Entry DOI: 10.7270/Q27M08MC |
More data for this
Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 3.20E+4 | -25.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Max-Planck-Institut fuer Biochemie
| Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t... |
J Mol Biol 301: 465-75 (2000)
Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM |
More data for this
Ligand-Target Pair | |
Tissue-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+6 | >-17.1 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Max-Planck-Institut fuer Biochemie
| Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t... |
J Mol Biol 301: 465-75 (2000)
Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM |
More data for this
Ligand-Target Pair | |
Amiloride-sensitive sodium channel subunit alpha
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
Parion Sciences Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay |
J Med Chem 49: 4098-115 (2006)
Article DOI: 10.1021/jm051134w
BindingDB Entry DOI: 10.7270/Q2FT8KNH |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| US Patent
| n/a | n/a | 781 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
| Assay Description
One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi... |
J Med Chem 49: 1668-83 (2006)
BindingDB Entry DOI: 10.7270/Q2C24ZRP |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Mus musculus (Mouse)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of mouse uPA |
Bioorg Med Chem Lett 29: (2019)
Article DOI: 10.1016/j.bmcl.2019.126753
BindingDB Entry DOI: 10.7270/Q2BV7M3S |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of human kidney uPA using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrate |
Bioorg Med Chem Lett 29: (2019)
Article DOI: 10.1016/j.bmcl.2019.126753
BindingDB Entry DOI: 10.7270/Q2BV7M3S |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM16173
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong
Curated by ChEMBL
| Assay Description
Inhibition of human uPA |
Bioorg Med Chem Lett 29: (2019)
Article DOI: 10.1016/j.bmcl.2019.126753
BindingDB Entry DOI: 10.7270/Q2BV7M3S |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |