Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM209861 (5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nirma University Curated by ChEMBL | Assay Description Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition | Eur J Med Chem 140: 1-19 (2017) Article DOI: 10.1016/j.ejmech.2017.08.045 BindingDB Entry DOI: 10.7270/Q2WD4385 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50315769 (3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nirma University Curated by ChEMBL | Assay Description Inhibition of human Aurora B/INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 120 mins | Eur J Med Chem 140: 1-19 (2017) Article DOI: 10.1016/j.ejmech.2017.08.045 BindingDB Entry DOI: 10.7270/Q2WD4385 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465482 (CHEMBL4288628) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465481 (CHEMBL4291472) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465478 (CHEMBL4286130) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50341520 (3-(4-(Piperidin-1-yl)benzoylamino)-5-(pyridin-4-yl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465486 (CHEMBL4282263) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465490 (CHEMBL4280041) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465485 (CHEMBL4292538) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465488 (CHEMBL4295011) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50226223 (CHEMBL302219) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465492 (CHEMBL4292942) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50341532 (3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465484 (CHEMBL4280308) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM34651 (Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | 5.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465483 (CHEMBL4291350) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 6.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465487 (CHEMBL1605269) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465489 (CHEMBL1201292) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 9.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465495 (CHEMBL4278218) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465477 (CHEMBL4285109) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465494 (CHEMBL4279867) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465491 (CHEMBL4278538) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465493 (CHEMBL4281678) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM15296 (6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465480 (CHEMBL4282410) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50465479 (CHEMBL4286709) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM47224 (US9073917, 2-inventive) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50277545 (4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Berne Curated by ChEMBL | Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay | J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50175305 (CHEMBL3600873) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Berne Curated by ChEMBL | Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay | J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167515 (US9073917, 12- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167510 (US9073917, 7- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167506 (US9073917, 1-inventive) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM117012 (US8637532, 739) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167508 (US9073917, 5- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167507 (US9073917, 4- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574278 (CHEMBL4854144) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM116525 (US8637532, 211) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167513 (US9073917, 10- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167516 (US9073917, 13- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167509 (US9073917, 6- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM209861 (5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Nirma University Curated by ChEMBL | Assay Description Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition | Eur J Med Chem 140: 1-19 (2017) Article DOI: 10.1016/j.ejmech.2017.08.045 BindingDB Entry DOI: 10.7270/Q2WD4385 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50244953 (CHEMBL4063500) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Binding affinity towards [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in HG108-15 | J Med Chem 61: 3166-3192 (2018) Article DOI: 10.1021/acs.jmedchem.8b00209 BindingDB Entry DOI: 10.7270/Q2KS6TZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167511 (US9073917, 8- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574272 (CHEMBL4875416) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574268 (CHEMBL4851020) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574269 (CHEMBL4857965) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574270 (CHEMBL4855657) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574279 (CHEMBL4869229) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM50574274 (CHEMBL4860970) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01087 BindingDB Entry DOI: 10.7270/Q2N01BBH | |||||||||||
More data for this Ligand-Target Pair |
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