Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [50-359]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [50-359] (Homo sapiens (Human))	BDBM50433916 (PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...) Show SMILES O=C1c2ccccc2-c2[nH]nc3cccc1c23 Show InChI InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	7.4	n/a
Universitätsklinikum Frankfurt					Assay Description Titrations were performed by a 0.4 µl injection followed by 19 successive injections (2 µl) of each compound(adenosine 500 µM, PS653 250 µM) into a 2...				Cell Chem Biol 23: 1193-1205 (2016) Article DOI: 10.1016/j.chembiol.2016.06.017 BindingDB Entry DOI: 10.7270/Q23N226C
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 [50-359] (Homo sapiens (Human))	BDBM199118 ((2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymeth...) Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	7.4	n/a
Universitätsklinikum Frankfurt					Assay Description Titrations were performed by a 0.4 µl injection followed by 19 successive injections (2 µl) of each compound(adenosine 500 µM, PS653 250 µM) into a 2...				Cell Chem Biol 23: 1193-1205 (2016) Article DOI: 10.1016/j.chembiol.2016.06.017 BindingDB Entry DOI: 10.7270/Q23N226C
					More data for this Ligand-Target Pair				3D Structure (crystal)